50 research outputs found

    Culture Care Needs of Puerto Rican Women Receiving HIV Care from Nurse Practitioners in New York City

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    The purpose of this mini-ethnonursing research study was to discover, describe, and interpret culture care values, beliefs, expressions, practices and needs of Puerto Rican women receiving HIV care from nurse practitioners (NPs) and other providers in New York City. The emic, or insider, perspective of Puerto Rican women living with HIV was the focus of this study and Leininger’s Culture Care Theory (CCT) provided the theoretical framework. Various enablers of the CCT, including Leininger’s Sunrise Enabler to Discover Culture Care, guided the design andimplementation of the study. Six key and twelve general informantswere interviewed and data from the interviews were coded using the QSR NVIVO10 software. Categories of data discovered through analysis included Puerto Rican female identity; self-care; caring for others; family and familismo; culture; personalismo and professional care; and, living with HIV. Other important data focused on experiences of various forms of discrimination; substance use; and, intimate partner violence. Sixteen patterns; and, five universal and one diverse theme emerged through analysis. Culture care decision and action modes were identified to assist providers to preserve and/or maintain, accommodate and/or negotiate, and repattern and/or restructure culture care practices, patterns, and experiences of Puerto Rican women receiving HIV care. Current HIV care practice emphasizes engaging patients in the HIV continuum of care and the culture care decision and action modes can enhance desired engagement. Implications for theory, research, practice, education, healthcare administration and healthcare policy were made based on the findings and analysis. These recommendations can improve delivery of care for diverse communities living with HIV

    A randomised trial of subcutaneous intermittent interleukin-2 without antiretroviral therapy in HIV-infected patients: the UK-Vanguard Study

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    Objective: The objective of the trial was to evaluate in a pilot setting the safety and efficacy of interleukin-2 (IL-2) therapy when used without concomitant antiretroviral therapy as a treatment for HIV infection. Design and Setting: This was a multicentre randomised three-arm trial conducted between September 1998 and March 2001 at three clinical centres in the United Kingdom. Participants: Participants were 36 antiretroviral treatment naive HIV-1-infected patients with baseline CD4 T lymphocyte counts of at least 350 cells/mm(3). Interventions: Participants were randomly assigned to receive IL-2 at 15 million international units (MIU) per day ( 12 participants) or 9 MIU/day ( 12 participants) or no treatment ( 12 participants). IL-2 was administered by twice-daily subcutaneous injections for five consecutive days every 8 wk. Outcome Measures: Primary outcome was the change from baseline CD4 T lymphocyte count at 24 wk. Safety and plasma HIV RNA levels were also monitored every 4 wk through 24 wk. The two IL-2 dose groups were combined for the primary analysis. Results: Area under curve (AUC) for change in the mean CD4 T lymphocyte count through 24 wk was 129 cells/mm(3) for those assigned IL-2 ( both dose groups combined) and 13 cells/mm(3) for control participants (95% CI for difference, 51.3 - 181.2 cells/mm(3); p = 0.0009). Compared to the control group, significant increases in CD4 cell count were observed for both IL-2 dose groups: 104.2/mm(3) ( p = 0.008) and 128.4 cells/mm(3) ( p = 0.002) for the 4.5 and 7.5 MIU dose groups, respectively. There were no significant differences between the IL-2 (0.13 log(10) copies/ ml) and control (0.09 log(10) copies/ml) groups for AUC of change in plasma HIV RNA over the 24-wk period of follow- up ( 95% CI for difference, - 0.17 to 0.26; p = 0.70). Grade 4 and dose-limiting side effects were in keeping with those previously reported for IL-2 therapy. Conclusions: In participants with HIV infection and baseline CD4 T lymphocyte counts of at least 350 cells/mm(3), intermittent subcutaneous IL-2 without concomitant antiretroviral therapy was well tolerated and produced significant increases in CD4 T lymphocyte counts and did not adversely affect plasma HIV RNA levels

    Surface and porous characterisation of activated carbons made from a novelbiomass precursor, the esparto grass

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    In the work now reported the production of activated carbons from a novel precursor, esparto grass, by activation with carbon dioxide is presented. The results show that the materials produced have interesting properties, namely BET apparent surface area and pore volume up to 1122 m(2) g(-1) and 0.46 cm(3) g(-1), respectively. The activated carbons have basic characteristics with point of zero charge between 9.25 and 10.27 and show a very fascinating structure, as shown by the SEM images. (C) 2012 Elsevier B.V. All rights reserved.The authors are grateful to the Fundacao para a Ciencia e Tecnologia (Portugal) and the European Regional Development Fund (FEDER) through the Operational Programme for Competitiveness Factors (COMPETE) and QREN for financial support through Project PTDC/CTM/66552/2006 (FCOMP-01-0124-FEDER-007142) and under the Strategic Project PEst-OE/QUI/UI0619/2011 (CQE/UE).Valente Nabais, J.; Laginhas, C.; Ribeiro Carrott, MML.; Carrott, PJM.; Crespo Amorós, JE.; Nadal Gisbert, AV. (2013). Surface and porous characterisation of activated carbons made from a novelbiomass precursor, the esparto grass. Applied Surface Science. 265:919-924. doi:10.1016/j.apsusc.2012.11.164S91992426

    Nivel de cumplimiento del dossier de cuidados en el Hospital Clínic

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    Màster en Administració i Gestió en Cures d'Infermeria de l'E.U. Santa Madrona, 1996, Director: Ferran Ferre

    Treatment Fatigue

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    Factores de riesgo predictores de la asimetría de miembros inferiores en jugadores de deportes de conjunto: ultimate fresbee

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    Objetivo: determinar los factores de riesgo predictores de la asimetría de los miembros inferiores en jugadores de Ultimate Frisbee. Metodología: Investigación con enfoque empírico analítico, estudio descriptivo correlacional, con una fase multivariada, los participantes corresponden a una muestra de 113 deportistas de 15 a 20 años pertenecientes a los clubes y ligas de Ultimate Frisbee. Resultados: los datos establecen características sociodemográficas y deportivas de los participantes del estudio, se determinó la asimetría de los miembros inferiores en jugadores de Ultimate Frisbee, se analizó los factores de riesgo intrínsecos y extrínsecos en los deportistas y sus relaciones con las asimetrías de miembros inferiores y finalmente se estimó un modelo predictivo de la asimetría en los participantes del estudio. Conclusiones: describen situaciones particulares a nivel de preparación deportiva, responsabilidades del deportista y seguimiento de los objetivos gubernamentales en el ámbito deportivo.Objective: to determine the predictive risk factors of lower limb asymmetry in Ultimate Frisbee players. Methodology: Research with an analytical empirical approach, correlational descriptive study, with a multivariate phase, the participants correspond to a sample of 113 athletes aged 15 to 20 years belonging to Ultimate Frisbee clubs and leagues. Results: the data establish sociodemographic and sports characteristics of the study participants, the asymmetry of the lower limbs was determined in Ultimate Frisbee players, the intrinsic and extrinsic risk factors in the athletes and their relationships with lower limb asymmetries were analyzed. and finally, a predictive model of asymmetry was estimated in the study participants. Conclusions: they describe particular situations at the level of sports preparation, responsibilities of the athlete and monitoring of government objectives in the sports field

    Metal contents in house geckos (Squamata: Gekkonidae) from industrial and urban areas of southern Tamaulipas, Mexico and western Andalucía, Spain, may reflect airborne metal pollution

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    House geckos share living quarters with humans in the tropical and subtropical regions inhabited by these reptiles. Gecko behavior, biological traits, continuous exposure to suspended particulate matter 0 µm in diameter (PM10) and dust, as well as status as exotic species, motivated the choice of these species to examine environmental exposure to ambient air pollutants, in particular metals, and subsequent accumulation in these organisms. One part of the study was conducted in Tamaulipas (Mexico) where Hemydactylus frenatus is abundant in urban and industrial environments, the other part was conducted in Andalucia (Spain) where Tarentola mauritanica is found in similar environments. Adult geckos were collected on buildings in locations affected by various air pollution sources. For both species, higher metal contents were observed in whole-body (including digestive tracts) analysis and were markedly different between collection sites. Contents in tails, digestive tracts, and carcasses without digestive tracts were not correlated. Based on contamination factor values, bioaccumulation in H. frenatus tissues occurred for 12 of the 15 metals analyzed. Data suggest that H. frenatus might serve as a biomonitor for Cu, Ni, Pb, Cr, Li, and V, whereas T. mauritanica might be a biomonitor for Cu, Ni, Pb, and Cr. To our knowledge, metal contents for H. frenatus are reported here for the first time. House gecko data could be integrated into a highly representative monitoring system and health risk assessments related to air quality in residential areas

    Hallmarks of gastrointestinal neuroendocrine tumours: implications for treatment

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    In the past few years, there have been advances in the treatment of neuroendocrine tumours (NETs) and improvements in our understanding of NET biology. However, the benefits to patients have been relatively modest and much remains yet to be done. The 'Hallmarks of Cancer', as defined by Hanahan and Weinberg, provide a conceptual framework for understanding the aberrations that underlie tumourigenesis and to help identify potential targets for therapy. In this study, our objective is to review the major molecular characteristics of NETs, based on the recently modified 'Hallmarks of Cancer', and highlight areas that require further research
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