Multiple rendezvous maneuvers at synchronous altitude

Rendezvous techniques between synchronous satellites were found using a cotangential elliptic phasing (CEP) transfer. This transfer is a closed elliptic orbit which is cotangent to the synchronous orbits of the chase vehicle and target satellite. The cotangent point lies on the line of apsides of the transfer orbit which coincides with the line of intersection of the synchronous orbits. The rendezvous maneuvers accomplish plane changes and phase shifts simultaneously, and these maneuvers are found to be optimal when the plane change is split equally between the velocity increments. The CEP transfer can be extended to several revolutions for a further reduction of fuel usage. A set of synchronous satellites was used in a simulated mission. An optimal sequence for rendezvous among these satellites was established such that the total sum of velocity increments is within the realm of estimated 1980 technology

The role of slag chemistry in dephosphorization : an equilibrium and kinetic study

Imperial Users onl

Effects of Δ⁹-tetrahydrocannabinol (THC) vapor inhalation in Sprague-Dawley and Wistar rats.

An inhalation system based on e-cigarette technology produces hypothermic and antinociceptive effects of Δ⁹-tetrahydrocannabinol (THC) in rats. Indirect comparison of some prior investigations suggested differential impact of inhaled THC between Wistar (WI) and Sprague-Dawley (SD) rats; thus, this study was conducted to directly compare the strains across inhaled and injected routes of administration. Groups (N = 8 per strain) of age-matched male SD and WI rats were prepared with radiotelemetry devices to measure temperature and then exposed to vapor from the propylene glycol (PG) vehicle or THC (25-200 mg/mL of PG) for 30 or 40 min. Additional studies evaluated effects of THC inhalation on plasma THC (50-200 mg/mL) and nociception (100-200 mg/mL) as well as the thermoregulatory effect of intraperitoneal injection of THC (5-30 mg/kg). Hypothermic effects of THC were more pronounced in SD rats, where plasma levels of THC were identical across strains, under either fixed inhalation conditions or injection of a mg/kg equivalent dose. Strain differences in hypothermia were largest after i.p. injection of THC, with SD rats exhibiting dose-dependent temperature reduction after 5 or 10 mg/kg, i.p. and the WI rats only exhibiting significant hypothermia after 20 mg/kg, i.p. The antinociceptive effects of inhaled THC (100, 200 mg/mL) did not differ significantly across the strains. These studies confirm an insensitivity of WI rats, compared with SD rats, to hypothermia induced by THC following inhalation conditions that produced identical plasma THC and antinociception. Thus, quantitative, albeit not qualitative, strain differences may be obtained when studying thermoregulatory effects of THC. (PsycInfo Database Record (c) 2021 APA, all rights reserved)

PITCH FUNCTION COMPARISON METHODOLOGY FOR SUPPORTING A SMART 3D SCANNER SELECTION

When working with 3Dscanner devices, one of the most critical problems is usually the low quality of the point cloud provided by the scanning device. This problem mainly consists of the following two aspects. The first one is surely the choice of the strategy used to acquire the object shape. Most of the times, the selected strategy is based on selective sampling. This choice proved to be valid, especially when working with Free-Form surfaces: by using a selective sampling strategy is in fact possible to limit point density increase to those regions showing high morphological complexity. The second aspect is the difficulty of identifying which 3Dscanner device is the one that better fulfils the specific application needs, which vary depending on the specific scenario in which the costumer/user works (resolution, accuracy, …). As far as this last issue is concerned, the presence of many different acquisition technologies and devices on the market is a source of confusion for the users, who sometimes choose the wrong solution instead of finding the most efficient one. Hence, in order to support the potential users in their selection, this paper aims to propose a solution able to integrate the morphological analysis of the object acquired with the costumer needs (resolution, accuracy, …) and with the 3Dscanner performances in order to help users to identify the optimal solutio

The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue

In recent years, use of psychoactive synthetic stimulants has grown rapidly. 5-(2-Aminopropyl)indole (5-IT) is a synthetic drug associated with a number of fatalities, that appears to be one of the newest 3,4-methylenedioxymethamphetamine (MDMA) replacements. Here, the monoamine-releasing properties of 5-IT, its structural isomer 6-(2-aminopropyl)indole (6-IT), and MDMA were compared using in vitro release assays at transporters for dopamine (DAT), norepinephrine (NET), and serotonin (SERT) in rat brain synaptosomes. In vivo pharmacology was assessed by locomotor activity and a functional observational battery (FOB) in mice. 5-IT and 6-IT were potent substrates at DAT, NET, and SERT. In contrast with the non-selective releasing properties of MDMA, 5-IT displayed greater potency for release at DAT over SERT, while 6-IT displayed greater potency for release at SERT over DAT. 5-IT produced locomotor stimulation and typical stimulant effects in the FOB similar to those produced by MDMA. Conversely, 6-IT increased behaviors associated with 5-HT toxicity. 5-IT likely has high abuse potential, which may be somewhat diminished by its slow onset of in vivo effects, whereas 6-IT may have low abuse liability, but enhanced risk for adverse effects. Results indicate that subtle differences in the chemical structure of transporter ligands can have profound effects on biological activity. The potent monoamine-releasing actions of 5-IT, coupled with its known inhibition of MAO A, could underlie its dangerous effects when administered alone, and in combination with other monoaminergic drugs or medications. Consequently, 5-IT and related compounds may pose substantial risk for abuse and serious adverse effects in human users

Alien Registration- Creehan, Michael C. (Millinocket, Penobscot County)

https://digitalmaine.com/alien_docs/7545/thumbnail.jp

Alien Registration- Creehan, Michael C. (Millinocket, Penobscot County)

https://digitalmaine.com/alien_docs/7545/thumbnail.jp