Prospectus, September 25, 1996

https://spark.parkland.edu/prospectus_1996/1022/thumbnail.jp

Prospectus, October 16, 1996

https://spark.parkland.edu/prospectus_1996/1025/thumbnail.jp

Pacts and Alliances: Why They Succeed, Why They Fail, and Why We Should Care

Streaming video requires RealPlayer to view.The University Archives has determined that this item is of continuing value to OSU's history.This conference brings together scholars and advanced graduate students to explore pacts and alliances, the mechanics of which have shaped history in fundamental ways, but whose presence has most often been ignored, taken for granted, and clearly understudied. Although sometimes pointing out reasons why a particular pact or alliance failed or succeeded in achieving its goals, historians largely have failed to say anything broader about the requisites necessary for the successful implementation of alliances. Drawing on both the nuanced work of historians and the structural expertise of social scientists, this conference aims to draw broad conclusions about the inner workings of this significant issue related to international security. Pacts and Alliances is organized around four fundamental but crucial questions. First, why do pacts and alliances generally fail in their aims? Second, what common denominators are shared by alliances and pacts that succeed in their objectives? Third, is it inevitable that pacts or alliances are destined to break down? And finally, what are the implications of these results on pact and alliance-making in the 21st century? The answers to these questions are critically important for the next generation of policy makers and international historians.Ohio State University. Mershon Center for International Security StudiesEvent Web page, streaming video, event photo

Prospectus, September 18, 1996

https://spark.parkland.edu/prospectus_1996/1021/thumbnail.jp

Prospectus, August 28, 1996

https://spark.parkland.edu/prospectus_1996/1018/thumbnail.jp

Prospectus, September 4, 1996

https://spark.parkland.edu/prospectus_1996/1019/thumbnail.jp

Diagnostic and prognostic value of procalcitonin among febrile critically ill patients with prolonged ICU stay

<p>Abstract</p> <p>Background</p> <p>Procalcitonin (PCT) has been proposed as a diagnostic and prognostic sepsis marker, but has never been validated in febrile patients with prolonged ICU stay.</p> <p>Methods</p> <p>Patients were included in the study provided they were hospitalised in the ICU for > 10 days, were free of infection and presented a new episode of SIRS, with fever >38°C being obligatory. Fifty patients fulfilled the above criteria. PCT was measured daily during the ICU stay. The primary outcome was proven infection.</p> <p>Results</p> <p>Twenty-seven out of 50 patients were diagnosed with infection. Median PCT on the day of fever was 1.18 and 0.17 ng/ml for patients with and without proven infections (p < 0.001). The area under the curve for PCT was 0.85 (95% CI; 0.71-0.93), for CRP 0.65 (0.46-0.78) and for WBC 0.68 (0.49-0.81). A PCT level of 1 ng/mL yielded a negative predictive value of 72% for the presence of infection, while a PCT of 1.16 had a specificity of 100%. A two-fold increase of PCT between fever onset and the previous day was associated with proven infection (p 0.001) (OR = 8.55; 2.4-31.1), whereas a four-fold increase of PCT of any of the 6 preceding days was associated with a positive predictive value exceeding 69.65%. A PCT value less than 0.5 ng/ml on the third day after the advent of fever was associated with favorable survival (p 0.01).</p> <p>Conclusion</p> <p>The reported data support that serial serum PCT may be a valuable diagnostic and prognostic marker in febrile chronic critically ill patients.</p

Serum procalcitonin for the early recognition of nosocomial infection in the critically ill patients: a preliminary report

<p>Abstract</p> <p>Background</p> <p>The usefulness of procalcitonin (PCT) measurement in critically ill medical patients with suspected nosocomial infection is unclear. The aim of the study was to assess PCT value for the early diagnosis of bacterial nosocomial infection in selected critically ill patients.</p> <p>Methods</p> <p>An observational cohort study in a 15-bed intensive care unit was performed. Seventy patients with either proven (n = 47) or clinically suspected but not confirmed (n = 23) nosocomial infection were included. Procalcitonin measurements were obtained the day when the infection was suspected (D0) and at least one time within the 3 previous days (D-3 to D0). Patients with proven infection were compared to those without. The diagnostic value of PCT on D0 was determined through the construction of the corresponding receiver operating characteristic (ROC) curve. In addition, the predictive value of PCT variations preceding the clinical suspicion of infection was assessed.</p> <p>Results</p> <p>PCT on D0 was the best predictor of proven infection in this population of ICU patients with a clinical suspicion of infection (AUROCC = 0.80; 95% CI, 0.68–0.91). Thus, a cut-off value of 0.44 ng/mL provides sensitivity and specificity of 65.2% and 83.0%, respectively. Procalcitonin variation between D-1 and D0 was calculated in 45 patients and was also found to be predictive of nosocomial infection (AUROCC = 0.89; 95% CI, 0.79–0.98) with a 100% positive predictive value if the +0.26 ng/mL threshold value was applied. Comparable results were obtained when PCT variation between D-2 and D0, or D-3 and D0 were considered. In contrast, CRP elevation, leukocyte count and fever had a poor predictive value in our population.</p> <p>Conclusion</p> <p>PCT monitoring could be helpful in the early diagnosis of nosocomial infection in the ICU. Both absolute values and variations should be considered and evaluated in further studies.</p

Quenched Cold Accretion of a Large Scale Metal-Poor Filament due to Virial Shocking in the Halo of a Massive z=0.7 Galaxy

Using HST/COS/STIS and HIRES/Keck high-resolution spectra, we have studied a remarkable HI absorbing complex at z=0.672 toward the quasar Q1317+277. The HI absorption has a velocity spread of 1600 km/s, comprises 21 Voigt profile components, and resides at an impact parameter of D=58 kpc from a bright, high mass [log(M_vir/M_sun) ~ 13.7] elliptical galaxy that is deduced to have a 6 Gyr old, solar metallicity stellar population. Ionization models suggest the majority of the structure is cold gas surrounding a shock heated cloud that is kinematically adjacent to a multi-phase group of clouds with detected CIII, CIV and OVI absorption, suggestive of a conductive interface near the shock. The deduced metallicities are consistent with the moderate in situ enrichment relative to the levels observed in the z ~ 3 Ly-alpha forest. We interpret the HI complex as a metal-poor filamentary structure being shock heated as it accretes into the halo of the galaxy. The data support the scenario of an early formation period (z > 4) in which the galaxy was presumably fed by cold-mode gas accretion that was later quenched via virial shocking by the hot halo such that, by intermediate redshift, the cold filamentary accreting gas is continuing to be disrupted by shock heating. Thus, continued filamentary accretion is being mixed into the hot halo, indicating that the star formation of the galaxy will likely remain quenched. To date, the galaxy and the HI absorption complex provide some of the most compelling observational data supporting the theoretical picture in which accretion is virial shocked in the hot coronal halos of high mass galaxies.Comment: 20 pages, 9 figures, submitted to Ap

A comparison of observed and simulated absorption from H i, C iv, and Si iv around z ≈ 2 star-forming galaxies suggests redshift–space distortions are due to inflows

We study H I and metal-line absorption around z ≈ 2 star-forming galaxies by comparing an analysis of data from the Keck Baryonic Structure Survey to mock spectra generated from the Evolution and Assembly of Galaxies and their Environments (EAGLE) cosmological, hydrodynamical simulations. We extract sightlines from the simulations and compare the properties of the absorption by H I, C IV, and Si IV around simulated and observed galaxies using pixel optical depths. We mimic the resolution, pixel size, and signal-to-noise ratio of the observations, as well as the distributions of impact parameters and galaxy redshift errors. We find that the EAGLE reference model is in excellent agreement with the observations. In particular, the simulation reproduces the high metal-line optical depths found at small galactocentric distances, the optical depth enhancements out to impact parameters of 2 proper Mpc, and the prominent redshift–space distortions which we find are due to peculiar velocities rather than redshift errors. The agreement is best for halo masses ∼1012.0 M⊙, for which the observed and simulated stellar masses also agree most closely. We examine the median ion mass-weighted radial gas velocities around the galaxies, and find that most of the gas is infalling, with the infall velocity depending on halo rather than stellar mass. From this, we conclude that the observed redshift–space distortions are predominantly caused by infall rather than outflows