Stages for the More Sustainable Farm

Currently, agricultural farm units are faced with a double and most times contradictory challenge, in order to be successful: on the one hand the invested capital has to be profitable and the economic performance has to be maximised. On the other hand, given the socio-environmental situation, it is necessary to preserve and to protect the environment and natural resources. Given the potential conflict of the two aims, since the satisfaction of one implies the underperformance of the other (and vice versa), the question then is: which is the solution to choose? We intend, in this work, to formulate a farm plan with the purpose of reconciling the criteria of environmental sustainability with that of economic competitiveness. For this achievement we proceed to the comparative study of sustainability of different groups of farms identified in the study area (first evaluation cycle) through MESMIS (“Marco para la Evaluación de Sistemas de Manejo de Recursos Naturales Mediante Indicadores de Sustentabilidad” - Framework for Evaluation of Natural-Resource Systems Handling through Sustainability Indicators) methodology, that allowed to select the more sustainable group of farms. Based on the found potentialities and weakness on these production systems, we stepped to the planning of a production unit of bovine meat, which obeys simultaneously to economic and environmental objectives, using Multicriteria Decision. We finished the work with the sustainability evaluation between groups of farms identified previously and the planned farms (second evaluation cycle), based, again, in the MESMIS methodology, to confirm (or not) the greatest sustainability of the last ones. Analyses of the results allow us to confirm the greatest relative sustainability of the planned farm, for the diverse traced scenarios.Decision taking, planning, sustainability, Environmental Economics and Policy, Farm Management,

Judicial Risk and Credit Market Performance: Micro Evidence from Brazil Payroll Loans

A large body of literature has stressed the institution-development nexus as critical in explaining differences in countries' economic performance. The empirical evidence, however, has been mainly at the aggregate level, associating macro performance with measures of quality of institutions. This paper, by relating a judicial decision on the legality of payroll debit loans in Brazil to bank-level decision variables, provides micro evidence on how creditor legal protection affects market performance. Payroll loans are personal loans with principal and interests payments directly deducted from the borrowers' payroll check, which, in practice, makes a collateral out of future income. In June 2004, a high-level federal court upheld a regional court ruling that had declared payroll deduction illegal. Using personal loans without payroll deduction as a control group, we assess whether the ruling had an impact on market performance. Evidence indicates that it had an adverse impact on risk perception, interest rates, and amount lent.

Biomarkers: a strategic tool in the assessment of environmental quality of coastal waters

Ecosystems are under the pressure of complex mixtures of contaminants whose effects are not always simple to assess. Biomarkers, acting as early warning signals of the presence of potentially toxic xenobiotics, are useful tools for assessing either exposure to, or the effects of these compounds providing information about the toxicant bioavailability. In fact, it has been argued that a full understanding of ecotoxicological processes must consider an integrated multi-level approach, in which molecular impact is related with higher-order biological consequences at the individual, population and community levels. Monitoring programs should make use of this tool to link contaminants and ecological responses fulfilling strategies like those launched by OSPAR (Commissions of Oslo and Paris) Convention on the protection of the marine environment of the North-East Atlantic and the International Council for the Exploration of the Sea (ICES). An overview of the work done in the past few years using biomarkers as in situ tools for pollution assessment in Portuguese coastal waters is presented as a contribution to the set up of a biomonitoring program for the Portuguese coastal zone. Considering the data set available the biomonitoring proposal should include the analysis of biomarkers and effects at individual levels. The aim of the program will include a spatial and temporal characterization of the biomarkers acetyl-cholinesterase, metallothioneins, DNA damage, adenylate energy charge and scope-for-growth levels. The investigation of the spatial variation of biomarkers is crucial to define sites for long term monitoring, which will be integrated with a chemical monitoring program. This framework will be a major contribution to the implementation of a national database for the use of biomarkers along the Portuguese coast.info:eu-repo/semantics/publishedVersio

An evaluation study for improving gap flow simulations in coastal areas on Portugal

Winds inferred by Synthetic Aperture Radar (SAR) satellites are a very important source of spatial wind field behavior along coastal areas particularly on small coastal areas that are temporary affected by strong flow disturbances mainly driven from land to the ocean. Gap flow circulations, among others, are an example of such wind phenomena disturbances which are not yet described by regional atmospheric models nor by CFD modeling. Such situations could compromise both offshore wind resource and park deployment studies on places affected by the presence of these phenomena types. A possible way to overcome this situation is the usage of SAR images assimilated into regional atmospheric models using certain type of assimilation techniques. In this work, a real case occurred in a coastal area in Portugal will be taken into account. A strong gap flow occurred during the beginning of the night 9 December 2010 was captured by a SAR image which was assimilated into the model. Some validation meteorological stations were used for validation purposes taken into account scenarios performed with and without wind SAR assimilation. Spatial results lead to the conclusion that the assimilation of SAR images improves the wind pattern results which reflects how SAR assimilation into the mesoscale models are important for simulating the coastal wind flow patterns

Determinants of self-medication with NSAIDs in a Portuguese community pharmacy

Licence CC BY-NC-ND http://creativecommons.org/licenses/by-nc-nd/4.0/"Background: Non-steroid anti-inflammatory drugs (NSAIDs) are a widely used therapeutic group in the world, and particularly in the Portuguese population. Objective: To compare NSAID’s use by prescription and self-medication acquisition and to determine the pattern of indication of NSAIDs, their usage profile and possible implications for patients’ safety. Methods: A cross-sectional design was used where individuals presenting at a community pharmacy requesting NSAIDs during the study period (one month) were invited to answer a face-to-face interview where socio-demographic characteristics, the indication pattern and previous experience of side effects were assessed. A follow-up interview was performed one week later to assess the incidence of adverse effects. The study was ethically approved. Results: A sample of 130 NSAIDs users was recruited, comprising mostly women (n=87; 66.9%), actively employed (n=77; 59.2%) and presenting a mean age of 49.5 years old (SD=20.49). An equal proportion of individuals acquired NSAIDs by self-medication and with medical prescription (n=65; 50%). Over 4/5 of patients (n=57; 87.7%) acquiring NSAIDs without a prescription were self-medicated by their own initiative, and only 10.8% (n=7) had been advised by the pharmacist. The most commonly acquired active substances were ibuprofen and diclofenac. Self-medicated users more frequently resorted to topical NSAIDs following short term treatments. The major underlying condition motivating NSAIDs sought were musculoskeletal disorders (45.0%), regardless of the regimen. An important proportion of prevalent users of NSAIDs reported previous experience of adverse effects (11.3%). One week after initiating NSAID therapy, a small proportion of patients reported incidence of adverse effects. Conclusion: Self-medication with NSAIDs is sought for numerous medical conditions. Reported adverse effects (prevalent and incident) confirm the need for a more rational use of NSAIDs and ongoing pharmacovigilance.

Feature selection optimization of risk factors for coronary heart disease

Cardiovascular disease is a worldwide problem and is the main cause of mortality when coronary heart disease leads to a heart attack. Hence, it is important to evaluate how to prevent this disease considering the symptoms description and physical examinations.This study points out the application and comparison of different performance measures for the classification of heart disease. Firstly, a feedforward neural network was applied to classify heart disease risk, using the well-known Framingham database. Feature selection optimization was performed to identify the most important variables to take into consideration, minimizing the Type II error and maximizing the accuracy. In addition, a multi-objective optimization algorithm was carried out to simultaneously optimize both performance measures. A set of non-dominated solutions representing the trade-offs between objectives were obtained, and gender, age, systolic blood pressure, and glucose level emerged as the principal factors to take into consideration to predict heart disease. The results obtained are promising and show the importance of considering more than one criterion to identify the most important variables.This work has been supported by FCT -Fundacao para a Ciencia e Tecnologia within the R&D Units Project Scope: UIDB/00319/2020

Implementation of robust multi-objective optimization in the build orientation problem

Additive manufacturing (AM) is an emerging technology to create 3D objects layer-by-layer directly from a 3D CAD model. The build orientation is a critical issue in AM and its optimization will significantly reduce the building costs and improve object accuracy. This paper aims to optimize the build orientation problem of a 3D CAD model using a robust multi-objective approach, taking into account the staircase effect and the support area characteristics. Thus, themain objective is to obtain a robust Pareto optimal front, composed of solutions that are not quite sensitive to perturbations in the variables. In this manner, a set of robust solutions is presented as alternatives and the decision-maker can identify the compromise solutions and choose according to his/her preferences.This work has been developed under the FIBR3D project - Hybrid processes based on additive manufacturing of composites with long or short fibers reinforced thermoplastic matrix (POCI-01-0145-FEDER-016414), supported by the Lisbon Regional Operational Programme 2020, under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). This work has been supported by FCT - Fundacao para a Ciencia e Tecnologia within the R&D Units Project Scope: UIDB/00319/2020

Environmental risk assessment in a contaminated estuary: an integrated weight of evidence approach as a decision support tool

Environmental risk assessment of complex ecosystems such as estuaries is a challenge, where innovative and integrated approaches are needed. The present work aimed at developing an innovative integrative methodology to evaluate in an impacted estuary (the Sado, in Portugal, was taken as case study), the adverse effects onto both ecosystem and human health. For the purpose, new standardized lines of evidence based on multiple quantitative data were integrated into a weight of evidence according to a best expert judgment approach. The best professional judgment for a weight of evidence approach in the present study was based on the following lines of evidence: i) human contamination pathways; ii) human health effects: chronic disease; iii) human health effects: reproductive health; iv) human health effects: health care; v) human exposure through consumption of local agriculture produce; vi) exposure to contaminated of water wells and agriculture soils; vii) contamination of the estuarine sedimentary environment (metal and organic contaminants); viii) effects on benthic organisms with commercial value; and ix) genotoxic potential of sediments. Each line of evidence was then ordinally ranked by levels of ecological or human health risk, according to a tabular decision matrix and expert judgment. Fifteen experts scored two fishing areas of the Sado estuary and a control estuarine area, in a scale of increasing environmental risk and management actions to be taken. The integrated assessment allowed concluding that the estuary should not be regarded as impacted by a specific toxicant, such as metals and organic compounds hitherto measured, but by the cumulative risk of a complex mixture of contaminants. The proven adverse effects on species with commercial value may be used to witness the environmental quality of the estuarine ecosystem. This method argues in favor of expert judgment and qualitative assessment as a decision support tool to the integrative management of estuaries. Namely it allows communicating environmental risk and proposing mitigation measures to local authorities and population under a holistic perspective as an alternative to narrow single line of evidence approaches, which is mandatory to understand cause and effect relationships in complex areas like estuaries.info:eu-repo/semantics/publishedVersio

Can you hear me now? The quest for better guidance on omega-3 fatty acid consumption to combat hearing loss

Pontifícia Universidade Católica de São Paulo (PUC-SP), Programa de Estudos Pós-Graduado em Fonoaudiologia, São Paulo/SP, BrazilEscola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), Departamento de Fonoaudiologia, São Paulo/SP, BrazilUniversidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Fonoaudiologia, Bauru/SP, BrazilEscola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), Disciplina de Neurociência, São Paulo/SP, BrazilEscola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), Departamento de Fonoaudiologia, São Paulo/SP, BrazilEscola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), Disciplina de Neurociência, São Paulo/SP, BrazilWeb of Scienc