Patients without colonoscopic follow-up after abnormal fecal immunochemical tests are often unaware of the abnormal result and report several barriers to colonoscopy.

BackgroundThe fecal immunochemical test (FIT) is the second most commonly used colorectal cancer (CRC) screening modality in the United States; yet, follow-up of abnormal FIT results with diagnostic colonoscopy is underutilized. Our objective was to determine patient-reported barriers to diagnostic colonoscopy following abnormal FIT in an academic healthcare setting.MethodsWe included patients age 50-75 with an abnormal FIT result between 1/1/2015 and 10/31/2017 and no documented follow-up diagnostic colonoscopy. We abstracted demographic data from the electronic health record (EHR). Study personnel conducted telephone surveys with patients to confirm colonoscopy completion and elicit data on notification of FIT results and barriers to colonoscopy. We also provided brief verbal education about diagnostic colonoscopy. We calculated frequencies of demographic data and survey responses and compared survey responses by interest in colonoscopy after education.ResultsWe surveyed 67 patients. Fifty-one were aware of the abnormal FIT result, and a majority learned of the abnormal FIT result by direct communication with providers (19, 37.3%) or EHR messaging (11, 21.6%). Overall, fifty-three patients (79.1%) confirmed lack of colonoscopy, citing provider-related (19, 35.8%), patient-related (16, 30.2%), system-related (1, 1.9%), or multifactorial (17, 32.1%) reasons. Lack of knowledge of FIT result (14, 26.4%) was most common. After brief education, 20 (37.7%) patients requested colonoscopy.ConclusionPatients with an abnormal FIT reported various multi-level barriers to diagnostic colonoscopy after abnormal FIT, including knowledge of FIT results. When provided with brief education, participants expressed interest in diagnostic colonoscopy. Future efforts will evaluate interventions to improve colonoscopy follow-up

Prototipo de vehículo autónomo; fase 1

Este proyecto cuenta con una tecnología parecida al dron, la única diferencia es que este es un vehículo terrestre. El objetivo principal es que se pueda manejar de forma manual y/o autónoma, para esto se necesita un controlador para manipular el GPS, Motores y Servos. El módulo de GPS se utiliza para conocer la ubicación exacta del vehículo en tiempo real, un transmisor RC de mínimo 4 canales para manejar el vehículo a largas distancias, y por último, un transmisor en el vehículo enviar información a una PC. Se necesita el programa Mission Planner para recibir dicha información y así conocer la ubicación actual del vehículo en todo momento para posibles ajustes o modificaciones.ITESO, A.C

Reproducción campesina, recursos naturales y género en una comunidad campesina en Puebla, México.

Men and women fulfill different functions in the reproduction oftheir domestic groups (DG) and in access, use and managementof natural resources to face limitations frequently imposed by thesocio-economic system and the natural environment. This essaypresents results of research conducted in San Antonio Juárez,Municipality of Tzicatlayocan, Puebla, where use and managementof natural resources were analyzed, as well as the reproductionstrategies that the inhabitants develop differentially by gender.The methodology used included applying a survey, performingin-depth interviews and participant observation. The mainreproduction strategies identified are production of crafts madeof palm, Mexican bamboo and giant reed, commercialized intraditional markets, agricultural activities associated to a systemof soil conservation with the construction of terraces or parapetsfor the cultivation of basic foods, extensive small-scale cattleproduction, production and sale of barbecued meat, and collectionand sale of forest resources such as firewood and medicinal plants,all of them activities where a clear gender division of labor isobserved.Hombres y mujeres desempeñan funciones diferentes en la reproducciónde sus grupos domésticos (GD) y en el acceso, uso ymanejo de recursos naturales para hacer frente a limitacionesimpuestas frecuentemente por el sistema socioeconómico y losentornos naturales. En este ensayo se presentan resultados deuna investigación realizada en San Antonio Juárez, Municipio deTzicatlacoyan, Puebla, en donde se analizó el uso y manejo derecursos naturales y las estrategias de reproducción que desarrollansus habitantes en forma diferencial por género. La metodologíaempleada incluyó la aplicación de una encuesta, entrevistasa profundidad y observación participante. Las principalesestrategias de reproducción identificadas son la producciónartesanal de palma, otate y carrizo, comercializados en mercadostradicionales, actividades agrícolas asociadas a un sistema de conservaciónde suelos con la construcción de terrazas o "pretiles"para el cultivo de alimentos básicos, la ganadería extensiva apequeña escala, la producción y venta de barbacoa y la recoleccióny venta de recursos forestales como leña y plantas medicinales,actividades en las que se observa una clara división genéricadel trabajo

Síntesis y evaluación catalítica de la zirconia sulfatada soportada en MCM-41 y SBA-16

El presente trabajo tiene la finalidad de realizar el estudio del comportamiento catalítico de un material súper-ácido el cual es zirconia sulfatada soportada en dos materiales mesoporosos con área específica considerable como son MCM-41 y SBA-16. Ambos sólidos fueron caracterizados por DRX, fisisorción de y SEM-EDS. Para comparar la actividad catalítica se realizó en una reacción de apertura nucleofílica de un epóxido con anilina para la obtención de un β-aminoalcohol.In the this work mineral zeolitic samples was analyzed, in powder form and heat treated 250, 350 and 500 ° C, respectively, which are of particular interest due to their catalytic properties. The treatment process consists of mechanical grinding of solid samples, process conducted for 3 hours, subsequently calcining the sample for 4 hours. The structural characterization of the materials was carried out by XRD, while morphology was determined by SEM and width bandgap materials by using RD-UV-Vis and Kubelka-Munk transform. Photo-degradation reaction of textile compound called, reactive black 5 dye (RB-5) was carried out in a batch reactor with a white light lamp of λ = 570 nm, ambient temperature and pressure; the kinetics of degradation reaction was monitored by checking the variation on absorption band (λ = 595 and 310 nm) with UV -Vis spectroscopy

Garantía de participación democrática en Ecuador, gobiernos estudiantiles y consejos de aulas

El presente trabajo de investigación, logra dar mayor sentido de satisfacción a las actividades realizadas por parte de los estudiantes. Toda institución requiere de estrategias comunicacionales, el objetivo del presente proyecto de investigación consiste en el estudio de un plan de comunicación para solucionar inconvenientes suscitados en la socialización de los reglamentos de los gobiernos estudiantiles y consejos de aula. Para fundamentar la investigación se utilizó el método deductivo y el método inductivo, así como las técnicas de la encuesta que fueron aplicadas a los estudiantes de varias instituciones educativas y las entrevistas que fueron dirigidas a las autoridades y personal responsable de las escuelas seleccionadas. La literatura que sostiene el marco teórico fue bibliográfica, que involucra fuentes primarias, secundarias y sitios de internet. De toda la revisión de los argumentos y aplicación de los métodos inciden en la falta de comunicación de las políticas internas. Se aplicó estrategias de comunicación, que permitió ampliar la socialización de los reglamentos de los gobiernos estudiantiles y consejos de aula para su posicionamiento en los estudiantes. La investigación es conveniente, porque aportará la vinculación entre autoridades, personal administrativo, estudiantes y padres de familia.The present research work, gives a greater sense of satisfaction to the activities carried out by students. Every institution requires communication strategies, the objective of this research project is the study of a communication plan to solve problems raised in the socialization of student government regulations and classroom councils. To base the investigation, the deductive method and the inductive method were used, as well as the survey techniques that were applied to the students of several educational institutions and the interviews that were directed to the authorities and responsible personnel of the selected schools. The literature that supports the theoretical framework was bibliographic, involving primary, secondary and Internet sites. All the review of the arguments and application of the methods affect the lack of communication of internal policies. Communication strategies were applied, which allowed to expand the socialization of the regulations of the student governments and classroom councils for their positioning in the students. The investigation is convenient, because it will provide the link between authorities, administrative staff, students and parents

Effective antimicrobial activity of ZnO and Yb-doped ZnO nanoparticles against Staphylococcus aureus and Escherichia coli

Nanostructured Zn1-xYbxO (0.0 ≤ x ≤ 0.1) powders were prepared by the solution method using polyvinyl alcohol (PVA) and sucrose. The effect of the ytterbium doping content on the structural, morphological, optical and antimicrobial properties was analyzed. X-ray diffraction (XRD) analysis revealed that the hexagonal wurtzite structure was retained, and no secondary phases due to doping were observed. The crystallite size was under 20nm for all the Zn1-xYbxO (0.0 ≤ x ≤ 0.1) powders. The optical band gap was calculated, and the results revealed that this value increased with the ytterbium content, and the Eg values varied from 3.06 to 3.10 eV. The surface chemistry of the powders was analyzed using X-ray photoelectron spectroscopy (XPS), and the results confirmed the oxidation state of ytterbium as 3+ for all the samples. Zn1-xYbxO (0.0 ≤ x ≤ 0.1) nanoparticles were tested as antimicrobial agents against Staphylococcus aureus and Escherichia coli, resulting in a potential antimicrobial effect at most of the tested concentrations. These results were used in an artificial neural network (ANN). The results showed that it is possible to generate a model capable of forecasting the absorbance with good precision (error of 1–2%)

Síntesis multicomponentes (MCR) de propargil aminas asistidas por microondas y catalizada por Cu-SBA-15

El presente trabajo muestra el comportamiento catalítico del material mesoporoso Cu-SBA-15 seco y calcinado, el cual fue caracterizado mediante DRX y SEM-EDS. El material se evaluó en una reacción multicomponentes asistida por microondas. Los resultados demostraron que el material sin calcinar tiene una mayor actividad catalítica en cada uno de los casos evaluados.The this work the catalytic behavior of dry and calcined Cu-SBA-15 are shown. The mesoporous salid was characterized by DRX and SEM¬EDS and then was evaluated in a multicomponent reaction assisted by microwaves. The results had that the material without calcining had greater catalytic activity in each of the evaluated cases

EL BONCHE año 4 Nº 10

Revista estudiantil de la Corporación Universitaria del Caribe

CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs

Mitochondria are essential organelles that host crucial metabolic pathways and produce adenosine triphosphate. The mitochondrial proteome is heterogeneous among tissues and can dynamically change in response to different metabolic conditions. Although the transcriptional programs that govern mitochondrial biogenesis and respiratory function are well known, posttranscriptional regulatory mechanisms remain unclear. In this study, we show that the cytosolic RNA-binding protein clustered mitochondria homologue (CLUH) regulates the expression of a mitochondrial protein network supporting key metabolic programs required under nutrient deprivation. CLUH exerts its function by controlling the stability and translation of target messenger RNAs. In the absence of Cluh, mitochondria are severely depleted of crucial enzymes involved in catabolic energy-converting pathways. CLUH preserves oxidative mitochondrial function and glucose homeostasis, thus preventing death at the fetal–neonatal transition. In the adult liver, CLUH ensures maximal respiration capacity and the metabolic response to starvation. Our results shed new light on the posttranscriptional mechanisms controlling the expression of mitochondrial proteins and suggest novel strategies to tailor mitochondrial function to physiological and pathological conditions.Peer reviewe