7,428 research outputs found
Sustainable Success: Motives and Small-Scale Charity Sport Events
Charity sport events are an effective and fun way to raise money for non-profit organizations and charitable causes. As more annual events are occurring, it is crucial to understand the primary consumers and contributors of charity sport events. Specifically, understanding the motives of charity event participants and sponsors is fundamental to not only increasing the event popularity but also sustaining it. Previous charity sport researchers have indicated that participant motives generally fall into three categories: social, health, and advocacy (Won et al., 2010), while sponsor motives are primarily philanthropy or social responsibility and increased brand recognition (Abratt et al., 1987). The purpose of this study was to discover if these same participant and sponsor motives hold true for a small-scale charity sport event. Participants and sponsors of the 2018 CoopStrong 4-Miler (n=256) were asked to complete an online survey consisting of demographic and open-ended questions regarding motives and their involvement in the CoopStrong event. The survey data were then analyzed using Nvivo 12 software. Using open-coding the researcher determined the most salient participant and sponsor motives. The results indicated that both participants and sponsors were motivated by four main themes. These themes were categorized as Personal Connection, ALS Awareness, F3/FiA Involvement, and Fitness. Due to underperformance and lack of participation, almost 1,000 charity sport events were cancelled in 2017 (Kadet, 2011). Consequently, CoopStrong and other charities must continue to better understand event sponsor and participant motives to ensure future and sustainable success
Assessing Medication Error Rates in Pediatrics Pre and Post Implementation of the Handtevy App within the San Antonio Fire Department
Goal: The goal of this project was to determine if the implementation of the Handtevy app reduced medication error rates on calls run by the San Antonio Fire Department in the pediatric population with a diagnosis involving pain management or seizure. Background: Prior to the implementation of the Handtevy app, first responders used a tool called the Broselow tape to estimate a child’s weight and to determine the appropriate medication dose. Run reports were analyzed prior to the implementation of the Handtevy pediatric standard to determine medication error rates for Fentanyl and Versed in pediatric patients 13 years or younger. Run reports were also analyzed after the implementation of the Handtevy app to determine medication error rates for Fentanyl and Versed in pediatric patients 13 years or younger. Medication error rates were compared pre and post Handtevy app implementation to determine if there was a difference. Methods: This was a retrospective study comparing a 3-month time period prior to the deployment of the Handtevy pediatric standard with a 3-month time period following full implementation of Handtevy. The dates of data being used were calls run from January 1, 2016 through March 31, 2016 and January 1, 2018 through March 31, 2018. 2017 was the implementation period. A call was defined as any response where the San Antonio Fire Department treated a pediatric patient for pain or seizure. No intervention was implemented in this study and no in-person recruitment of subjects was needed. SAFD electronic medical records were collected from the Southwest Texas Regional Advisory Council (STRAC) database. Data extraction begun by selecting all SAFD EMS run reports in the STRAC region involving pain management or a seizure within the time period of January 1, 2016 through March 31, 2016 and January 1, 2018 through March 31, 2018. Eligibility criteria included: children 13 years or younger treated by the San Antonio Fire Department. Children not treated for pain or seizure or children over the age of 13 and adults were excluded from data collection and analysis. Impact: Cumulative medication error rates decreased from 83% in Q1 2016 to 44.4% in Q1 2018 and medication usage increased by 58% from 2016 to 2018. This could be due to the increase in patients seen in 2018 versus 2016. This study revealed a disproportionate use of narcotics to reported pain in children and in turn may promote more frequent use of narcotics in children with the use of the Handtevy app in the future. The results of this study could also potentially encourage the shift from using the Broselow Tape for weight estimation leading to medication dosage calculations to using only the Handtevy app to provide predetermined medication dosages
Research-active therapists and therapy trainees: The need for continuity and clinical significance in our research
Mick Cooper is Professor of Counselling Psychology, as well as Acting Director of the Centre for Research in Psychological Wellbeing (CREW) at the University of Roehampton. Aside from being a research-active practitioner, with research interests in counselling with children and young people as well as humanistic, existential and relational approaches to therapy, Mick is co-developer of the pluralistic approach to therapeutic practice. He has published numerous research articles and texts including his latest book ‘Psychology at the Heart of Social Change: Developing a Progressive Vision for Society’. Mick kindly agreed to be interviewed by two of our editors (Deborah Bailey-Rodriguez & Eva Fragkiadaki) to discuss qualitative research within psychotherapy and counselling research, his own research journey as a therapist and to give us tips and pointers for therapy trainees and bridging the gap between research and therapeutic practice for our Special Issue
Perceptually smooth timbral guides by state-space analysis of phase-vocoder parameters
Sculptor is a phase-vocoder-based package of programs
that allows users to explore timbral manipulation
of sound in real time. It is the product
of a research program seeking ultimately to perform
gestural capture by analysis of the sound a
performer makes using a conventional instrument.
Since the phase-vocoder output is of high dimensionality —
typically more than 1,000 channels per
analysis frame—mapping phase-vocoder output to
appropriate input parameters for a synthesizer is
only feasible in theory
Enantioselective synthesis of non-proteinogenic 2-arylallyl-α-amino acids via Pd/In catalytic cascades
An efficient synthesis of both R- and S-enantiomers of 2-arylallyl-α-amino acids via a diastereoselective Pd/In mediated catalytic allylation of chiral N-sulfinyl-α-imino esters is described. The potential for further enhancement of molecular complexity and creating contiguous chiral centres by interfacing these processes with catalytic cyclisation–anion capture methodology is demonstrated
SLoMo: automated site localization of modifications from ETD/ECD mass spectra
Recently, software has become available to automate localization of phosphorylation sites from CID data and to assign associated confidence scores. We present an algorithm, SLoMo (Site Localization of Modifications), which extends this capability to ETD/ECD mass spectra. Furthermore, SLoMo caters for both high and low resolution data and allows for site-localization of any UniMod post-translational modification. SLoMo accepts input data from a variety of formats (e.g., Sequest, OMSSA). We validate SLoMo with high and low resolution ETD, ECD, and CID data
Sprint-based exercise and cognitive function in adolescents.
Moderate intensity exercise has been shown to enhance cognition in an adolescent population, yet the effect of high-intensity sprint-based exercise remains unknown and was therefore examined in the present study. Following ethical approval and familiarisation, 44 adolescents (12.6 ± 0.6 y) completed an exercise (E) and resting (R) trial in a counter-balanced, randomised crossover design. The exercise trial comprised of 10 × 10 s running sprints, interspersed by 50 s active recovery (walking). A battery of cognitive function tests (Stroop, Digit Symbol Substitution (DSST) and Corsi blocks tests) were completed 30 min pre-exercise, immediately post-exercise and 45 min post-exercise. Data were analysed using mixed effect models with repeated measures. Response times on the simple level of the Stroop test were significantly quicker 45 min following sprint-based exercise (R: 818 ± 33 ms, E: 772 ± 26 ms; p = 0.027) and response times on the complex level of the Stroop test were quicker immediately following the sprint-based exercise (R: 1095 ± 36 ms, E: 1043 ± 37 ms; p = 0.038), while accuracy was maintained. Sprint-based exercise had no immediate or delayed effects on the number of items recalled on the Corsi blocks test (p = 0.289) or substitutions made during the DSST (p = 0.689). The effect of high intensity sprint-based exercise on adolescents' cognitive function was dependant on the component of cognitive function examined. Executive function was enhanced following exercise, demonstrated by improved response times on the Stroop test, whilst visuo-spatial memory and general psycho-motor speed were unaffected. These data support the inclusion of high-intensity sprint-based exercise for adolescents during the school day to enhance cognition
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
We used on-line electron capture dissociation (ECD) for the large scale identification and localization of sites of phosphorylation. Each FT-ICR ECD event was paired with a linear ion trap collision-induced dissociation (CID) event, allowing a direct comparison of the relative merits of ECD and CID for phosphopeptide identification and site localization. Linear ion trap CID was shown to be most efficient for phosphopeptide identification, whereas FT-ICR ECD was superior for localization of sites of phosphorylation. The combination of confident CID and ECD identification and confident CID and ECD localization is particularly valuable in cases where a phosphopeptide is identified just once within a phosphoproteomics experiment
Serum neuron-specific enolase in children's cancer.
To test its diagnostic potential and sensitivity in paediatric malignancy, serum NSE was measured at diagnosis in 191 children with solid tumours and 25 with acute leukaemia. In stages I + II, III + IV and IVs neuroblastoma median levels were 18.0, 91.0 and 24.0 ng ml-1 respectively. For Wilms' patients, median values for stages I, II, III and IV disease were 16.6, 18.0, 29.0 and 47.0 ng ml-1 respectively. High levels of NSE were also found in patients with other types of tumour. Children in clinical remission after treatment for neuroblastoma invariably had normal NSE levels (mean +/- s.d. = 9.2 +/- 3.0 ng ml-1) even though the majority had radiologically identifiable residual disease. The values rose when relapse was radiologically or clinically obvious. We conclude (a) that, though levels of greater than 100 ng ml-1 are highly suggestive of advanced neuroblastoma, caution should be exercised in using serum NSE as a diagnostic test in children with cancer and (b) that serum NSE levels are not a sensitive index of residual neuroblastoma in patients, with initially elevated levels, that are receiving treatment
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The co-development and feasibility-testing of an innovative digital animation intervention (DAISI) to reduce the risk of maternal sepsis in the postnatal period
YesIntroduction: Sepsis is one of the most common causes of mortality in postnatal women globally and many other women
who develop sepsis are left with severe morbidity. Women’s knowledge of postnatal sepsis and how it can be prevented by
simple changes to behaviour is lacking.
Methods: This paper describes the co-development and feasibility testing of a digital animation intervention called DAISI
(digital animation in service improvement). This DAISI is designed to enhance postnatal women’s awareness of sepsis and
how to reduce their risk of developing the condition. We co-designed the digital animation over a six-month period underpinned
by theory, best evidence and key stakeholders, translated it into Urdu then assessed its use, firstly in a focus group
with women from different Black, Asian and Minority Ethnic (BAME) groups and secondly with 15 clinical midwives and
15 women (including BAME women). Following exposure to the intervention, midwives completed a questionnaire developed
from the COM-B behaviour change model and women participated in individual and focus group interviews using
similar questions.
Results: The animation was considered acceptable, culturally sensitive and simple to implement and follow.
Discussion: DAISI appears to be an innovative solution for use in maternity care to address difficulties with the postnatal
hospital discharge process. We could find no evidence of digital animation being used in this context and recommend a study
to test it in practice prior to adopting its use more widely. If effective, the DAISI principle could be used in other maternity
contexts and other areas of the NHS to communicate health promotion information.This study was funded by Translate Medtech, Leeds City Region. DAISI was developed by HMA Digital, Barnsley, UK
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