A comparison of semi-deterministic and stochastic search techniques

This paper presents an investigation of two search techniques, tabu search (TS) and simulated annealing (SA), to assess their relative merits when applied to engineering design optimisation. Design optimisation problems are generally characterised as having multi-modal search spaces and discontinuities making global optimisation techniques beneficial. Both techniques claim to be capable of locating globally optimum solutions on a range of problems but this capability is derived from different underlying philosophies. While tabu search uses a semi-deterministic approach to escape local optima, simulated annealing uses a complete stochastic approach. The performance of each technique is investigated using a structural optimisation problem. These performances are then compared to each other as well as a steepest descent (SD) method

Assessing Mesopelagic Zooplankton Food Web Connections at Ocean Station Papa Using Stable Isotope Analysis of Individual Amino Acids

M.S

The Story of Here: A Graphic Guide to Holy Cross and College Hill

This illustrated guide captures the history of the section of Worcester where the College of the Holy Cross is located. Historical sources and imaginative interpretations based on historical research are combined to create a unique then and now approach and experience of double vision to tell the story of College Hill. This guide was a project of Montserrat Seminar 111N, taught by Prof. Sarah Luria in Spring 2020.https://crossworks.holycross.edu/hc_books/1051/thumbnail.jp

Retinal vascular function in asymptomatic individuals with a positive family history of cardiovascular disease

Purpose To compare retinal microvascular function in healthy individuals with and without a positive family history (FH) of cardiovascular disease (CVD). Methods Retinal vessel reactivity was assessed by means of dynamic retinal vessel analysis in 38 healthy subjects aged between 30 and 66 years with a positive FH of CVD and 37 age‐ and gender‐matched control subjects. Other assessments included blood pressure (BP) profiles, blood glucose and lipid metabolism markers, Framingham risk scores (FRS), carotid intima‐media thickness (c‐IMT) and brachial flow‐mediated dilation (FMD). Results Family history‐positive subjects showed decreased retinal arterial baseline diameter fluctuation, dilation amplitude, percent dilation, and overall constriction response slope (p = 0.001; p = 0.015; p = 0.001; and p 0.05). The arterial MC% correlated negatively with decreased high‐density lipoprotein cholesterol (r = −0.52, p = 0.002) in only FH‐positive group. Conclusion Although macrovascular function is preserved in individuals with FH positive for CVD but with low FRS, there are, however, functional impairments at the retinal microvascular level that correlate with established plasma markers for cardiovascular risk

Heterogeneous Relationships between Labor Income and Health by Race/Ethnicity

Objective. To examine the race-stratified relationships between labor income and health among working-age adults in the United States. Data Sources. Data from eight waves of the Panel Study of Income Dynamics from 1999 through 2013 were used for this study. Study Design. The study utilized a retrospective observational longitudinal design with repeated measures of labor income and health measures. System-generalized method of moment and heteroscedasticity-based instrument regressions were used to examine the relationships between labor income and physical and mental health measures, respectively. Dynamic panel models were used to examine the effect of loss in income on health measures. Data Collection/Extraction Methods. We performed secondary data analysis. Principal Findings. Adults in higher labor income quartiles had better self-rated health than those in the lowest quartile regardless of racial group. The relationship between labor income and psychological distress varied by race groups. Reductions in labor income were associated with increases in psychological distress among whites only. Conclusion. These findings suggest heterogeneous relationships between labor income and overall health across racial groups. Our results highlight the need to provide safety nets for adults who experience a decline in income to prevent deterioration in health

Mapping post-glacial expansions: The peopling of Southwest Asia

Archaeological, palaeontological and geological evidence shows that post-glacial warming released human populations from their various climate-bound refugia. Yet specific connections between these refugia and the timing and routes of post-glacial migrations that ultimately established modern patterns of genetic variation remain elusive. Here, we use Y-chromosome markers combined with autosomal data to reconstruct population expansions from regional refugia in Southwest Asia. Populations from three regions in particular possess distinctive autosomal genetic signatures indicative of likely refugia: one, in the north, centered around the eastern coast of the Black Sea, the second, with a more Levantine focus, and the third in the southern Arabian Peninsula. Modern populations from these three regions carry the widest diversity and may indeed represent the most likely descendants of the populations responsible for the Neolithic cultures of Southwest Asia. We reveal the distinct and datable expansion routes of populations from these three refugia throughout Southwest Asia and into Europe and North Africa and discuss the possible correlations of these migrations to various cultural and climatic events evident in the archaeological record of the past 15,000 years