12 research outputs found

    Rapport II.10. De quelques problèmes posés par l'utilisation de ventilateurs de tirage dans les grands réfrigérants

    No full text
    A few problems linked to the use of fans in draught cooling towers. This communication goes into a few problems linked to the use of fans in induced draught cooling towers. First, the choice of the ventilation must be made considering criteria of plume and noise. We then deal with the study of a single fan, especially its characteristics determination from tests on a model or on the site. Finally, we consider the problems resulting from the parallel grouping of several fans .Cette communication passe en revue un certain nombre de problèmes liés à l'utilisation des ventilateurs dans les réfrigérants à tirage induit de grande puissance. Tout d'abord, le choix global de la ventilation sera fait en tenant compte de la montée du panache et du bruit des ventilateurs. L'étude d'un ventilateur isolé de réfrigérant est abordée, et notamment en ce qui concerne la détermination de ses caractéristiques à partir d'essais sur maquette ou sur site. On aborde enfin les problèmes résultant du groupement en parallèle de plusieurs ventilateurs sur une alimentation commune .Combès J.-F., Montussaint D. de, Amiard P., Barat M., Cavaillé Y. Rapport II.10. De quelques problèmes posés par l'utilisation de ventilateurs de tirage dans les grands réfrigérants. In: Rejets de chaleur à l'atmosphère. Gestion des calories et hydraulique associée. Compte rendu des XVIes journées de l'hydraulique. Paris, 16-18 septembre 1980. Tome 1, 1980

    Online coupling of immunoextraction, digestion, and microliquid chromatography-tandem mass spectrometry for the analysis of sarin and soman-butyrylcholinesterase adducts in human plasma

    No full text
    International audienceOrganophosphorus nerve agent (OPNA) adducts formed with human butyrylcholinesterase (HuBuChE) can be used as biomarker of OPNAs exposure. Indeed, intoxication by OPNAs can be confirmed by the LC/MS 2 analysis of a specific HuBuChE nonapeptide on which OPNAs covalently bind. A fast, selective and highly sensitive on‐line method was developed to detect sarin and soman‐adducts in plasma, including immunoextraction by anti‐HuBuChE antibodies, pepsin digestion on Immobilized Enzyme Reactors (IMER) and microLC‐MS 2 analysis of the OPNA‐adducts. The potential of three different monoclonal antibodies, covalently grafted on sepharose, were compared for the extraction of HuBuChE. The on‐line method developed with the most promising antibodies allowed to extract up to 100% of HuBuChE contained in plasma and to digest 45% of it in less than 40 min. Moreover, OPNA‐HuBuChE adducts, aged OPNA‐adducts and unadducted HuBuChE could be detected (with S/N> 2000), even in plasma spiked with low concentration of OPNA (10 ng.mL ‐1). Finally, the potential of this method was compared to approaches involving other affinity sorbents, already described for HuBuChE extraction

    Introduction

    No full text
    corecore