Energy and variance optimization of many body wave functions

We present a simple, robust and efficient method for varying the parameters in a many-body wave function to optimize the expectation value of the energy. The effectiveness of the method is demonstrated by optimizing the parameters in flexible Jastrow factors, that include 3-body electron-electron-nucleus correlation terms, for the NO$_2$ and decapentaene (C$_{10}$H$_{12}$) molecules. The basic idea is to add terms to the straightforward expression for the Hessian that are zero when the integrals are performed exactly, but that cancel much of the statistical fluctuations for a finite Monte Carlo sample. The method is compared to what is currently the most popular method for optimizing many-body wave functions, namely minimization of the variance of the local energy. The most efficient wave function is obtained by optimizing a linear combination of the energy and the variance.Comment: 4 pages, 4 figures, minor corrections of inexact statements, missing

Developing enterprise culture in a northern educational authority in the UK: involving trainee teachers in learning-orientated evaluation

In this paper we discuss our use of innovative methods - at least in the context of regeneration evaluation - to help evaluate an enterprise project in northern England, paying particular attention to the involvement of trainee teachers. We discuss the methods used and critically appraise the methods and methodology, present some emerging findings from the trainee teachers strand and conclude by discussing the place of what might be termed 'learning-orientated evaluation' in relation to the currently dominant output-focussed evaluation paradigm.</p

Academic citizenship and wellbeing: An exploratory cross-cultural study of South African and Swedish academic perceptions

Academic citizenship is, conceptually speaking, closely related to organisational citizenship behaviour, as both concepts can be regarded as consisting essentially of personal co-worker and organisational support behaviours. Academics across the world operate in widely divergent settings in different socioeconomic and political situations and higher education environments. Such differing circumstances might be expected to have a bearing on the priorities that academics face in different countries and the ways academic citizenship is understood. This paper uses a mixed methods approach to analyse perceptions of academic citizenship and employee well-being in one Swedish and one South African university which operate in starkly different socioeconomic circumstances. The findings of the exploratory study suggest that despite wide-ranging differences in socioeconomic environments between the two countries, there is a high degree of common understanding of the form and substance of academic citizenship and its bearing on well-being. Key words Academic citizenship, organisational citizenship behaviour, South African and Swedish universities, well-bein

Using evidence-informed logic models to bridge methods in educational evaluation

Designs combining different types of data are increasingly used in educational evaluation, to provide both evidence of impact and an explanation of the processes by which impacts are created. Logic models are visual representations of how an intervention leads via a set of steps from resources and inputs to outputs and then sets of outcomes. Their use has become widespread to underpin evaluations; and they have become of more interest in education as they have been promoted by policy makers and funders including the Education Endowment Foundation (EEF) in England. This paper addresses the question: how can logic models be used to frame and implement educational evaluations using combinations of methods? To do so, the paper draws on theory-based evaluation literature to identify a set of issues to be considered: the role of implementation logic; causal mechanisms; the context of interventions; and the importance of considering and addressing issues around complexity. Using detailed examples from two study designs for EEF evaluations, the paper presents an evidence-informed logic model approach to deal with these issues. The paper concludes by reflecting on the practical and theoretical implications of this approach, laying out a set of key issues to address in future evaluations for which a design framed by an evidence-informed logic model may be appropriate

Evidence-informed teaching: self-assessment tool for teachers

This tool for teachers is a product of the data collection and analysis, including interviews with 82 teachers, carried out as part of a DfE-funded study Evidence-informed teaching: an evaluation of progress in England (Coldwell et al, 2017). It is designed to help teachers evaluate and consider their levels of interaction with evidence in terms of awareness, engagement and use; and illustrate, based on real examples and quotes, what different levels of interaction look like in more or less evidence-informed schools. It is jointly published with The Chartered College of Teachers and is freely available for download on its website

SMART precision interferometry at 794 nm

Single-mode fibers have been used in the near-infrared to dramatically reduce calibration error for long-baseline interferometry. We have begun an effort to apply the advantages of spatial filtering at visible wavelengths for precision measurements of pulsating Cepheids using the IOTA interferometer. Rather than employing photometric taps to calibrate fluctuating coupling efficiency, we are using an "asymmetric" coupler which allows this calibration to be done without losing photons. The Single-Mode Asymmetric Recombination Technique (SMART) experiment has finished lab-testing, and has been installed at IOTA for full commissioning in Summer 2002. We report the results of lab characterization and first sky tests, as well as first fringes on a star using a visible-wavelength single-mode coupler. With both lab and sky experience using unpolarized light, we have found that circular silica fibers are quite practical for precision interferometric measurements. We conclude that circular fibers (as opposed to polarization maintaining fibers) have an undeserved poor reputation and that birefringence effects pose no significant difficulty

Phenomemology of a Realistic Accelerating Universe Using Tracker Fields

We present a realistic scenario of tracking of scalar fields with varying equation of state. The astrophysical constraints on the evolution of scalar fields in the physical universe are discussed. The nucleosynthesis and the galaxy formation constraints have been used to put limits on $\Omega_\phi$ and estimate $\epsilon$ during cosmic evolution. Interpolation techniques have been applied to estimate $\epsilon\simeq0.772$ at the present epoch. The epoch of transition from matter to quintessence dominated era and consequent onset of acceleration in cosmic expansion is calculated and taking the lower limit $\Omega_n^0 = 0.2$ as estimated from $SN_e I_a$ data, it is shown that the supernova observations beyond redshift $z=1$ would reveal deceleration in cosmic expansion.Comment: 10 pages, 4 figures, late

The human insulin receptor mRNA contains a functional internal ribosome entry segment.

Regulation of mRNA translation is an important mechanism determining the level of expression of proteins in eukaryotic cells. Translation is most commonly initiated by cap-dependent scanning, but many eukaryotic mRNAs contain internal ribosome entry segments (IRESs), providing an alternative means of initiation capable of independent regulation. Here, we show by using dicistronic luciferase reporter vectors that the 5'-UTR of the mRNA encoding human insulin receptor (hIR) contains a functional IRES. RNAi-mediated knockdown showed that the protein PTB was required for maximum IRES activity. Electrophoretic mobility shift assays confirmed that PTB1, PTB2 and nPTB, but not unr or PTB4, bound to hIR mRNA, and deletion mapping implicated a CCU motif 448 nt upstream of the initiator AUG in PTB binding. The IR-IRES was functional in a number of cell lines, and most active in cells of neuronal origin, as assessed by luciferase reporter assays. The IRES was more active in confluent than sub-confluent cells, but activity did not change during differentiation of 3T3-L1 fibroblasts to adipocytes. IRES activity was stimulated by insulin in sub-confluent cells. The IRES may function to maintain expression of IR protein in tissues such as the brain where mRNA translation by cap-dependent scanning is less effective