Impact of paracetamol pack size restrictions on poisoning from paracetamol in England and Wales: an observational study.

BACKGROUND: About 500 drug poisoning deaths involving paracetamol (acetaminophen) occur every year in England and Wales. To reduce the number of deaths, regulations were introduced in 1998 to restrict the sale of paracetamol. In this paper, we evaluate the impact of these regulations. METHODS: Mortality data for England and Wales were provided by the Office for National Statistics. Deaths were defined as due to compound paracetamol (paracetamol in combination with another analgesic, a low dose opioid or other ingredients) or paracetamol only, with or without alcohol or other drugs. The Department of Health provided data on all hospital admissions with a primary diagnosis of paracetamol poisoning. RESULTS: Mortality rates for paracetamol only were similar for males and females, and decreased from about 4.5 to 2.8 per million between 1997 and 1999 and again from about 3.1 to 2.2 per million between 2001 and 2002. These falls may be attributable to random variation in the rates. Deaths involving compound paracetamol, which were not subject to the 1998 regulations, remained relatively constant over the study period. There was evidence of a decreasing trend in paracetamol only mortality rates and this followed overall trends for other drug poisoning excluding opioids and drugs of misuse. Hospital admissions due to paracetamol poisoning increased from about 27 000 to 33 000 between 1995/1996 and 1997/1998 and then decreased to 25 000 in 2001/2002. There were almost 50 per cent more admissions for females than males, with the highest admission rates amongst females aged 15-24 years old. CONCLUSIONS: Between 1993 and 2002, mortality rates and hospital admissions due to paracetamol poisoning declined. However, the contribution of the 1998 regulations to this decline is not clear. Paracetamol poisoning continues to be an important public health issue in England and Wales and represents significant workload for the NHS in England

Continued and intensified hostility: The problematisation of immigration in the UK government’s 2021 New Plan for Immigration

Drawing on Bacchi’s (2009) ‘What’s the problem represented to be?’ framework, this article provides a critical analysis of HM Government’s (2021a) New Plan for Immigration. We explore how immigration is problematised, the assumptions that underlie these problematisations, alternative ways of representing the ‘problem’ of immigration, and the possible effects of the proposed reforms. Our article demonstrates how the New Plan is increasingly hostile towards, not only ‘illegal’ migrants, but an ever-widening group of people and organisations who may be viewed as facilitating illegal entry (organised criminals, hauliers) and/or those held responsible for preventing/delaying their removal (lawyers). The government’s proposals risk creating a two-tiered system, increasing the exclusion experienced by those seeking asylum, and widening the net of those held responsible for immigration control. Ultimately, we conclude that while the sentiments behind the government’s New Plan may not be all that ‘new’, they are nevertheless significant for their continuation and intensification of existing hostile policies and practices relating to immigration in the UK. This is especially so, given a number of recent global events that could have provided an opportunity to disrupt the government’s problematisation of, and hostility towards, people seeking refuge

The disjuncture between confidence and cooperation: Police contact amongst Polish migrants and established residents

Trust and confidence in such criminal justice institutions as the police is considered crucial for the successful functioning of society and to allow for greater voluntary compliance and cooperation with institutions of control. There is a plethora of existing research however that shows the often strained relationships between the police and particular ethnic minority groups in the UK, Europe and the US, with such groups exhibiting a great deal of mistrust and lack of cooperation. This article aims to add to this body of literature by presenting the findings of a case study that used quantitative and qualitative methods to explore new Polish migrants' and established local residents' trust and cooperation with the police following a period of mass migration in a small working class town in the North West of England. The key results show that, contrary to expectation, Polish migrants in fact hold greater trust in the police than do the more established local residents in the area. Notwithstanding this high confidence, Polish migrants remain reluctant to contact the police. Adding greater complexity to Tyler's (2006; Tyler and Fagan, 2008) 'normative' model of police contact, the article presents the nuances of police relations with majority and minority groups in this working class town

Student motivations for studying criminology: a narrative inquiry

The number of students studying criminology at university has significantly increased. Yet, criminology students have been all but ignored in research, despite being key stakeholders and ambassadors in the criminological enterprise. Drawing on the analysis of twelve in-depth interviews, we explore why students are motivated to study criminology and how these motivations are linked to their past experiences and future aspirations. Using a narrative inquiry, three types of stories emerged through our analysis: stories about (1) building on existing interests; (2) understanding the 'self'; and (3) securing 'justice' and ‘helping’ others. The stories students tell about their exposure to ‘crime’ help motivate their decision to study criminology, while their engagement with the discipline, enables them to make sense of these previous experiences and of themselves

Cost-effectiveness of eye care services in Zambia.

OBJECTIVE: To estimate the cost-effectiveness of cataract surgery and refractive error/presbyopia correction in Zambia. METHODS: Primary data on costs and health related quality of life were collected in a prospective cohort study of 170 cataract and 113 refractive error/presbyopia patients recruited from three health facilities. Six months later, follow-up data were available from 77 and 41 patients who had received cataract surgery and spectacles, respectively. Costs were determined from patient interviews and micro-costing at the three health facilities. Utility values were gathered by administering the EQ-5D quality of life instrument immediately before and six months after cataract surgery or acquiring spectacles. A probabilistic state-transition model was used to generate cost-effectiveness estimates with uncertainty ranges. RESULTS: Utility values significantly improved across the patient sample after cataract surgery and acquiring spectacles. Incremental costs per Quality Adjusted Life Years gained were US$259 for cataract surgery and US$ 375 for refractive error correction. The probabilities of the incremental cost-effectiveness ratios being below the Zambian gross national income per capita were 95% for both cataract surgery and refractive error correction. CONCLUSION: In spite of proven cost-effectiveness, severe health system constraints are likely to hamper scaling up of the interventions

Generation ZX(X)

This document discusses the design and development of Generation ZX(X), a hybrid multi-media event which explored how video games and performance can enhance and complement one another and enliven different types of historical data: oral herstories, lived experience, collective memory and audio-video archives.Generation ZX(X) was a hybrid of live and virtual components: an audiowalk, a social play session (3 video games were developed and played in a pop-up arcade), a film projection and a musical performance. For Generation ZX(X), I worked with third year Games and Art students and staff from Abertay University. The event took place on the 4th May 2018, in Camperdown Park, and at the JTC Furniture Group – the former Timex Camperdown factory. The event was developed as part of Mona Bozdog’s SGSAH ARCS (Applied Research Collaborative Studentship) PhD - Playing with Performance/ Performing Play. Creating hybrid experiences at the fringes of video games and performance.The project engaged with the living memory and heritage of the Timex factory in Dundee, and its aim was to reclaim and rewrite the history of the charged site on Harrison Road and to challenge the ‘official’ history of the local games industry. The project explored the hidden figures of the video games industry: the women who assembled the ZX Spectrum computers in the Timex factory in Dundee, and the ramifications that this labour had for the city’s development as one of UK’s leading games development and education centres. <br/

A Synthetic 21-cm Galactic Plane Survey of an SPH Galaxy Simulation

We have created synthetic neutral hydrogen (HI) Galactic Plane Survey data cubes covering 90 degrees < l < 180 degrees, using a model spiral galaxy from SPH simulations and the radiative transfer code TORUS. The density, temperature and other physical parameters are fed from the SPH simulation into TORUS, where the HI emissivity and opacity are calculated before the 21-cm line emission profile is determined. Our main focus is the observation of Outer Galaxy `Perseus Arm' HI, with a view to tracing atomic gas as it encounters shock motions as it enters a spiral arm interface, an early step in the formation of molecular clouds. The observation of HI self-absorption features at these shock sites (in both real observations and our synthetic data) allows us to investigate further the connection between cold atomic gas and the onset of molecular cloud formation.Comment: MNRAS accepted; 11 pages, 12 figure

Statistics on indigenous peoples: International effort needed

In 2007, the UN General Assembly endorsed the United Nations Declaration on the Rights of Indigenous Peoples. In the following years, there has been a strong call from a range United Nations agencies and spokespersons for countries to act to improve their statistics relating to Indigenous peoples as part of their response to the Declaration. These calls have emphasised the need for a holistic approach, describing strengths and resilience of Indigenous peoples and not just a focus on gaps and disadvantage. National responses have been mixed and overall statistics remain inadequate. Significantly, there has been no international statistical effort through the United Nations statistical structures to respond to the Declaration and the increasing array of calls for improved statistics. The United Nations Statistical Commission in particular has an array of mechanisms to study statistical needs and develop solutions across a broad international statistical agenda. It is time for countries to make a concerted effort to improve their own statistics on Indigenous peoples, and to insist that the Statistical Commission work in partnership with the Permanent Forum on Indigenous Issues and other stakeholders to lead a major international drive to improve statistics on and for Indigenous peoples

Experiences of shame and intellectual disabilities:two case studies

Abstract Background Shame is a trans-diagnostic phenomenon which underlies a variety of mental health difficulties. People with Intellectual Disabilities (ID) are reported to be one of the most stigmatised and excluded groups in society, and are more likely to experience mental health problems than the general population. Consequently, this group may be at significant risk of shame-related distress. However, a lack of research has been conducted which investigates the experience of shame in people with ID, and there is currently a lack of interventions targeting shame in people with ID. Method Two case studies were undertaken to document the experiences of stigma, discrimination and shame in people with ID, and to explore how shame may present in this population. Results Shame was found to be a significant barrier to social inclusion and can contribute towards poor psychological health in people with ID. Conclusions The development of interventions which specifically target shame in this population are required