2,774 research outputs found

    Using Non-Parametric Tests to Evaluate Traffic Forecasting Performance.

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    This paper proposes the use of a number of nonparametric comparison methods for evaluating traffic flow forecasting techniques. The advantage to these methods is that they are free of any distributional assumptions and can be legitimately used on small datasets. To demonstrate the applicability of these tests, a number of models for the forecasting of traffic flows are developed. The one-step-ahead forecasts produced are then assessed using nonparametric methods. Consideration is given as to whether a method is universally good or good at reproducing a particular aspect of the original series. That choice will be dictated, to a degree, by the user’s purpose for assessing traffic flow

    Detection of eight different tospovirus species by a monoclonal antibody against the common epitope of NSs protein

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    Rabbit antisera against the nucleocapsid protein (NP) have been commonly used for detection of tospoviruses and classification into serogroups or serotypes. Mouse monoclonal antibodies (MAbs) with high specificity to the NPs have also been widely used to identify tospovirus species. Recently, a serogroup-specific MAb against the NSs protein of Watermelon silver mottle virus (WSMoV) was produced by our laboratory to react with five members of WSMoV serogroup, i.e., WSMoV, Capsicum chlorosis virus (CaCV), Calla lily chlorotic spot virus (CCSV), Peanut bud necrosis virus (PBNV) and Watermelon bud necrosis virus (WBNV). The epitope recognized by the NSs MAb was determined and the comparison with the reported sequences of tospoviral NSs proteins revealed that the epitope is highly conserved at the N-terminal region of NSs proteins among members of WSMoV and Iris yellow spot virus (IYSV) serogroups, and Melon yellow spot virus (MYSV) serotype. When the NSs MAb was further used to react with the crude antigens of MYSV serotype, IYSV and Tomato yellow ring virus (TYRV) of IYSV serogroup, strong serological reactions, both in ELISA and western blotting, were observed. Thus, our results indicated that the NSs MAb is a useful and convenient tool for detection of the eight tospovirus species. It is also suggested that these eight Asian-type tospoviruses, i.e., WSMoV, CaCV, CCSV, PBNV, WBNV, MYSV, IYSV and TYRV, may share a common evolutionary ancesto

    The PMS project: Poor Man's Supercomputer

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    We briefly describe the Poor Man's Supercomputer (PMS) project carried out at Eotvos University, Budapest. The goal was to develop a cost effective, scalable, fast parallel computer to perform numerical calculations of physical problems that can be implemented on a lattice with nearest neighbour interactions. To this end we developed the PMS architecture using PC components and designed a special, low cost communication hardware and the driver software for Linux OS. Our first implementation of PMS includes 32 nodes (PMS1). The performance of PMS1 was tested by Lattice Gauge Theory simulations. Using SU(3) pure gauge theory or bosonic MSSM on PMS1 we obtained 3/Mflopand0.45/Mflop and 0.45Mflop price-to-sustained performance for double and single precision operations, respectively. The design of the special hardware and the communication driver are freely available upon request for non-profit organizations.Comment: Latex, 13 pages, 6 figures included, minor additions, typos correcte

    Permutation Randomization Methods for Testing Measurement Equivalence and Detecting Differential Item Functioning in Multiple-Group Confirmatory Factor Analysis

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    In multigroup factor analysis, different levels of measurement invariance are accepted as tenable when researchers observe a nonsignificant (Δ)χ2 test after imposing certain equality constraints across groups. Large samples yield high power to detect negligible misspecifications, so many researchers prefer alternative fit indices (AFIs). Fixed cutoffs have been proposed for evaluating the effect of invariance constraints on change in AFIs (e.g., Chen, 2007; Cheung & Rensvold, 2002; Meade, Johnson, & Braddy, 2008). We demonstrate that all of these cutoffs have inconsistent Type I error rates. As a solution, we propose replacing χ2 and fixed AFI cutoffs with permutation tests. Randomly permuting group assignment results in average between-group differences of zero, so iterative permutation yields an empirical distribution of any fit measure under the null hypothesis of invariance across groups. Our simulations show that the permutation test of configural invariance controls Type I error rates better than χ2 or AFIs when the model contains parsimony error (i.e., negligible misspecification) but the factor structure is equivalent across groups (i.e., the null hypothesis is true). For testing metric and scalar invariance, Δχ2 and permutation yield similar power and nominal Type I error rates, whereas ΔAFIs yield inflated errors in smaller samples. Permuting the maximum modification index among equality constraints control familywise Type I error rates when testing multiple indicators for lack of invariance, but provide similar power as using a Bonferroni adjustment. An applied example and syntax for software are provided

    The Principle Library Buildings of the University of North Carolina in Chapel Hill in Context

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    This paper is a history of the four library buildings that housed the principle library over the course of the University of North Carolina at Chapel Hill's history. The four buildings are Smith Hall, Carnegie Library, Louis Round Wilson Library, and Walter Royal Davis Library. The histories of these buildings are examined in the context of general academic library buildings trends in the United States. Special interest is devoted to the effects from increasing enrollment at universities, complementary growth in the size of collections, and the changing pedagogy of higher education. As enrollment and collections increased, and educational techniques changed, new library buildings were needed to replace existing buildings at the University of North Carolina at Chapel Hill. The period covered is 1853-1984

    Multigluon tree amplitudes with a pair of massive fermions

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    We consider the calculation of n-point multigluon tree amplitudes with a pair of massive fermions in QCD. We give the explicit transformation rules of this kind of massive fermion-pair amplitudes with respect to different reference momenta and check the correctness of them by SUSY Ward identities. Using these rules and onshell BCFW recursion relation, we calculate the analytic results of several n-point multigluon amplitudes.Comment: 15page

    Towards laser based improved experimental schemes for multiphoton e+ e- pair production from vacuum

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    Numerical estimates for pair production from vacuum in the presence of strong electromagnetic fields are derived, for two experimental schemes : the First concerns a laser based X-FEL and the other imitates the E144 experiment. The approximation adopted in this work is that of two level multiphoton on resonance. Utilizing achievable values of laser beam parameters, an enhancedproduction efficiency of up to 10^11 and 10^15 pairs can be obtained, for the two schemes respectively.Comment: 6 pages, 4 figure

    Targeted molecular therapeutics for Parkinson's Disease: A role for antisense oligonucleotides?

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    Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by marked heterogeneity in clinical symptoms and a complex genetic background..
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