681 research outputs found
The Spitzer c2d Survey Of Nearby Dense Cores. VII. Chemistry And Dynamics In L43
We present results from the Spitzer Space Telescope and molecular line observations of nine species toward the dark cloud L43. The Spitzer images and molecular line maps suggest that it has a starless core and a Class I protostar evolving in the same environment. CO depletion is seen in both sources, and DCO(+) lines are stronger toward the starless core. With a goal of testing the chemical characteristics from pre- to protostellar stages, we adopt an evolutionary chemical model to calculate the molecular abundances and compare with our observations. Among the different model parameters we tested, the best-fit model suggests a longer total timescale at the pre-protostellar stage, but with faster evolution at the later steps with higher densities.NSF AST-0307250, AST0607793NASA NNX07AJ72GNational Research Foundation of Korea (NRF) government (MEST) 2009-0062865KOSEF R012007- 000-20336-0Astronom
The Spitzer c2d Survey Of Nearby Dense Cores. XI. Infrared And Submillimeter Observations Of CB130
We present new observations of the CB130 region composed of three separate cores. Using the Spitzer Space Telescope, we detected a Class 0 and a Class II object in one of these, CB130-1. The observed photometric data from Spitzer and ground-based telescopes are used to establish the physical parameters of the Class 0 object. Spectral energy distribution fitting with a radiative transfer model shows that the luminosity of the Class 0 object is 0.14-0.16 L-circle dot, which is low for a protostellar object. In order to constrain the chemical characteristics of the core having the low-luminosity object, we compare our molecular line observations to models of lines including abundance variations. We tested both ad hoc step function abundance models and a series of self-consistent chemical evolution models. In the chemical evolution models, we consider a continuous accretion model and an episodic accretion model to explore how variable luminosity affects the chemistry. The step function abundance models can match observed lines reasonably well. The best-fitting chemical evolution model requires episodic accretion and the formation of CO2 ice from CO ice during the low-luminosity periods. This process removes C from the gas phase, providing a much improved fit to the observed gas-phase molecular lines and the CO2 ice absorption feature. Based on the chemical model result, the low luminosity of CB130-1 is explained better as a quiescent stage between episodic accretion bursts rather than being at the first hydrostatic core stage.NASA 1224608, 1288664, 1407, NNX07AJ72G, 1279198, 1288806, 1342425NSF AST-0607793, AST-0708158Korea government (MEST) 2009-0062866Ministry of Education, Science and Technology 2010-0008704Astronom
Feasibility of CO2 mitigation and carbohydrate production by microalga Scenedesmus obliquus CNW-N used for bioethanol fermentation under outdoor conditions: effects of seasonal changes
Differential Gene Expression in Response to Papayaringspot virus Infection in Cucumis metuliferus UsingcDNA- Amplified Fragment Length PolymorphismAnalysis
A better understanding of virus resistance mechanisms can offer more effective strategies to control virus diseases. Papayaringspot virus (PRSV), Potyviridae, causes severe economical losses in papaya and cucurbit production worldwide. However,no resistance gene against PRSV has been identified to date. This study aimed to identify candidate PRSV resistance genesusing cDNA-AFLP analysis and offered an open architecture and transcriptomic method to study those transcriptsdifferentially expressed after virus inoculation. The whole genome expression profile of Cucumis metuliferus inoculated withPRSV was generated using cDNA-amplified fragment length polymorphism (cDNA-AFLP) method. Transcript derivedfragments (TDFs) identified from the resistant line PI 292190 may represent genes involved in the mechanism of PRSVresistance. C. metuliferus susceptible Acc. 2459 and resistant PI 292190 lines were inoculated with PRSV and subsequentlytotal RNA was isolated for cDNA-AFLP analysis. More than 400 TDFs were expressed specifically in resistant line PI 292190. Atotal of 116 TDFs were cloned and their expression patterns and putative functions in the PRSV-resistance mechanism werefurther characterized. Subsequently, 28 out of 116 candidates which showed two-fold higher expression levels in resistant PI292190 than those in susceptible Acc. 2459 after virus inoculation were selected from the reverse northern blot andbioinformatic analysis. Furthermore, the time point expression profiles of these candidates by northern blot analysissuggested that they might play roles in resistance against PRSV and could potentially provide valuable information forcontrolling PRSV disease in the future
An Analysis of the Environments of FU Orionis Objects with Herschel
We present Herschel-HIFI, SPIRE, and PACS 50-670 {\mu}m imaging and
spectroscopy of six FU Orionis-type objects and candidates (FU Orionis, V1735
Cyg, V1515 Cyg, V1057 Cyg, V1331 Cyg, and HBC 722), ranging in outburst date
from 1936-2010, from the "FOOSH" (FU Orionis Objects Surveyed with Herschel)
program, as well as ancillary results from Spitzer-IRS and the Caltech
Submillimeter Observatory. In their system properties (Lbol, Tbol, line
emission), we find that FUors are in a variety of evolutionary states.
Additionally, some FUors have features of both Class I and II sources: warm
continuum consistent with Class II sources, but rotational line emission
typical of Class I, far higher than Class II sources of similar
mass/luminosity. Combining several classification techniques, we find an
evolutionary sequence consistent with previous mid-IR indicators. We detect [O
I] in every source at luminosities consistent with Class 0/I protostars, much
greater than in Class II disks. We detect transitions of 13CO (J_up of 5 to 8)
around two sources (V1735 Cyg and HBC 722) but attribute them to nearby
protostars. Of the remaining sources, three (FU Ori, V1515 Cyg, and V1331 Cyg)
exhibit only low-lying CO, but one (V1057 Cyg) shows CO up to J = 23 - 22 and
evidence for H2O and OH emission, at strengths typical of protostars rather
than T Tauri stars. Rotational temperatures for "cool" CO components range from
20-81 K, for ~ 10^50 total CO molecules. We detect [C I] and [N II] primarily
as diffuse emission.Comment: 31 pages, 15 figures; accepted to Ap
Herschel HIFI observations of O toward Orion: special conditions for shock enhanced emission
We report observations of molecular oxygen (O) rotational transitions at
487 GHz, 774 GHz, and 1121 GHz toward Orion Peak A. The O2 lines at 487 GHz and
774 GHz are detected at velocities of 10-12 km/s with line widths 3 km/s;
however, the transition at 1121 GHz is not detected. The observed line
characteristics, combined with the results of earlier observations, suggest
that the region responsible for the O emission is 9" (6e16 cm) in size, and
is located close to the H2 Peak 1position (where vibrationally-excited H
emission peaks), and not at Peak A, 23" away. The peak O2 column density is
1.1e18/cm2. The line velocity is close to that of 621 GHz water maser emission
found in this portion of the Orion Molecular Cloud, and having a shock with
velocity vector lying nearly in the plane of the sky is consistent with
producing maximum maser gain along the line-of-sight. The enhanced O
abundance compared to that generally found in dense interstellar clouds can be
explained by passage of a low-velocity C-shock through a clump with preshock
density 2e4/cm3, if a reasonable flux of UV radiation is present. The postshock
O can explain the emission from the source if its line of sight dimension
is ~10 times larger than its size on the plane of the sky. The special geometry
and conditions required may explain why O emission has not been detected in
the cores of other massive star-forming molecular clouds.Comment: 28 pages, 13 figure
Non-vitamin K antagonist oral anticoagulants in atrial fibrillation patients without previous oral anticoagulants or stable under warfarin: a nationwide cohort study.
AimsInvestigations on non-VKA oral anticoagulants (NOACs) for atrial fibrillation (AF) patients without taking any oral anticoagulants (OACs) or staying well on warfarin were limited. We aimed to investigate the associations between stroke prevention strategies and clinical outcomes among AF patients who were previously well without taking any OACs or stayed well on warfarin for years.Methods and resultsThe retrospective analysis included a total of 54 803 AF patients who did not experience an ischaemic stroke or intra-cranial haemorrhage (ICH) for years after AF was diagnosed. Among these patients, 32 917 patients who did not receive OACs were defined as the 'original non-OAC cohort' (group 1), and 8007 patients who continuously received warfarin were defined as the 'original warfarin cohort' (group 2). In group 1, compared to non-OAC, warfarin showed no significant difference in ischaemic stroke (aHR 0.979, 95%CI 0.863-1.110, P = 0.137) while those initiated NOACs were associated with lower risk (aHR 0.867, 95%CI 0.786-0.956, P = 0.043). When compared to warfarin, the composite of 'ischaemic stroke or ICH' and 'ischaemic stroke or major bleeding' was significantly lower in the NOAC initiator with an aHR of 0.927 (95%CI 0.865-0.994; P = 0.042) and 0.912 (95%CI 0.837-0.994; P ConclusionsThe NOACs should be considered for AF patients who were previously well without taking OACs and those who were free of ischaemic stroke and ICH under warfarin for years
Herschel observations of EXtraordinary Sources: Analysis of the full Herschel/HIFI molecular line survey of Sagittarius B2(N)
A sensitive broadband molecular line survey of the Sagittarius B2(N)
star-forming region has been obtained with the HIFI instrument on the Herschel
Space Observatory, offering the first high-spectral resolution look at this
well-studied source in a wavelength region largely inaccessible from the ground
(625-157 um). From the roughly 8,000 spectral features in the survey, a total
of 72 isotopologues arising from 44 different molecules have been identified,
ranging from light hydrides to complex organics, and arising from a variety of
environments from cold and diffuse to hot and dense gas. We present an LTE
model to the spectral signatures of each molecule, constraining the source
sizes for hot core species with complementary SMA interferometric observations,
and assuming that molecules with related functional group composition are
cospatial. For each molecule, a single model is given to fit all of the
emission and absorption features of that species across the entire 480-1910 GHz
spectral range, accounting for multiple temperature and velocity components
when needed to describe the spectrum. As with other HIFI surveys toward massive
star forming regions, methanol is found to contribute more integrated line
intensity to the spectrum than any other species. We discuss the molecular
abundances derived for the hot core, where the local thermodynamic equilibrium
approximation is generally found to describe the spectrum well, in comparison
to abundances derived for the same molecules in the Orion KL region from a
similar HIFI survey.Comment: Accepted to ApJ. 64 pages, 14 figures. Truncated abstrac
Clinical Study Clinical Evaluation of CyberKnife in the Treatment of Vestibular Schwannomas
Objective. This study assessed the posttreatment tumor control and auditory function of vestibular schwannoma (VS) patients after CyberKnife (CK) and analyzed the possible prognostic factors of hearing loss. Methods. We retrospectively studied 117 VS patients, with Gardner-Robertson (GR) classification grades I to IV, who underwent CK between 2006 and 2012. Data including radiosurgery treatment parameters, pre-and postoperative tumor size, and auditory function were collected and examined. Results. With CK, 117 patients had excellent tumor control rates (99.1%), with a mean imaging followup of 61.1 months. Excluding 52 patients (GR III-IV pretreatment), 53 (81.5%) of the remaining 65 patients (initial GR I-II) maintained GR I or II hearing after CK, with a mean audiometric followup of 64.5 months. Twelve patients experienced hearing degradation (91.6% were GR II pretreatment); they appeared to have significantly larger tumor sizes, significantly smaller cochlear sizes, and higher prescribed cochlear doses, compared to the patients with preserved hearing. Conclusion. Our data showed that CK treatment provided an excellent tumor control rate and a comparable hearing preservation rate in VS patients. Patients with pretreatment GR II hearing levels, larger tumor volumes, smaller cochlear sizes, and higher prescribed cochlear doses may have poor hearing prognoses
- …