Understanding Older Vehicle Users: An Interpretative Approach

Future adaptations in vehicle design should be linked in some parts to the age-related changes often faced by the older users. The aim of this research is to investigate the multiple age-related changes of Chinese older vehicle users in order to assist designers to better understand current and future older users’ needs. Although qualitative interpretative approaches have rarely been applied in the field of traffic gerontology research, they are widely used in current design research to explore persons’ lived experiences, behaviours and emotions. Therefore, this study employed qualitative research methods consisting of observation, interview, travel logbook and co-discovery to explore older vehicle users’ travel needs. The interpretative analysis confirmed that multiple methods such as interview, travel logbook, and co-discovery are useful to gain a holistic understanding of older drivers’ travel needs. However, the one journey driving observation cannot provide valuable categories to explore older users’ multiple travel needs due to daily living context absence in the one trip experiment. It is clear that the useful methods for determining research for older users will depend on the product. The findings demonstrate that Chinese future older generations are more concerned about their age-related differences from social and cultural perspective rather than physiological perspective. Social and cultural context play important role to shape older vehicle users’ future travel needs. From design a point of view, understanding the social activity and cultural context surrounds older vehicle users should make it possible to predict older drivers’ needs related to vehicle property. Keywords: Older Vehicle Users; Cultural Context; Social Context; Vehicle Design; Qualitative Research</p

Angle stability and outflow in dual blade ab interno trabeculectomy with active versus passive chamber management.

PurposeTo compare intraoperative angle stability and postoperative outflow of two ab interno trabeculectomy devices that excise the trabecular meshwork with or without active aspiration and irrigation. We hypothesized that anterior segment optical coherence tomography (AS-OCT) allows for a quantitative comparison of intraoperative angle stability in a microincisional glaucoma surgery (MIGS) pig eye training model.MethodsTwelve freshly enucleated porcine eyes were measured with AS-OCT at baseline, at the beginning of the procedure and at its conclusion to determine the anterior chamber depth (ACD) and the nasal angle α in degrees. The right and left eye of pairs were randomly assigned to an active dual blade goniectome (aDBG) and a passive dual blade goniectome (pDBG) group, respectively. The aDBG had irrigation and aspiration ports while the pDBG required surgery under viscoelastic. We performed the procedures using our MIGS training system with a standard, motorized ophthalmic operating microscope. We estimated outflow by obtaining canalograms with fluorescent spheres.ResultsIn aDBG, the nasal angle remained wide open during the procedure at above 90° and did not change towards the end (100±10%, p = 0.9). In contrast, in pDBG, ACD decreased by 51±19% to 21% below baseline (p&lt;0.01) while the angle progressively narrowed by 40±12% (p&lt;0.001). Canalograms showed a similar extent of access to the outflow tract with the aDBG and the pDBG (p = 0.513). The average increase for the aDBG in the superonasal and inferonasal quadrants was between 27 to 31% and for the pDBG between 15 to 18%.ConclusionAS-OCT demonstrated that active irrigation and aspiration improved anterior chamber maintenance and ease of handling with the aDBG in this MIGS training model. The immediate postoperative outflow was equally good with both devices

Numerical Modeling of Flow and Water Quality in an Oxbow Lake in the Mississippi Delta

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchive

Improving the Channel Utilization of Basic Safety Message in VANETs with Superposition Coded Modulation

In this paper, we propose a broadcast scheme to effectively utilize the scarce and shared wireless medium for vehicular ad-hoc networks (VANETs). By using superposition coded modulation (SCM), information elements that comprise basic safety messages (BSMs) were delivered with different service qualities determined by real-time traffic situations. The optimal power allocation strategy and achievable performance gain of the proposed method were first theoretically analyzed. To apply the proposed method into practice, the hierarchical quadrature amplitude modulation technology was then employed to implement the proposed SCM-based broadcast scheme for VANETs. To evaluate the performance of the proposed method in real-time traffic environments, a joint traffic-communication simulation was further conducted. Results agree that the proposed method extends the coverage of the BSM broadcast while maintaining an acceptable communication reliability to meet the requirement of driving safety

Impacts of Agricultural Activities on Water Quality in Oxbow Lakes in the Mississippi Delta

Mini-Symposium: Modeling Methodology for Agricultural Researc

Numerical Modeling of Salinity and Sediement Transport in Lake Pontchartrain During the Bonnet Carre Spillway Flood Release

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Numerical Simulation of Chemical Spills and Assessment of Environmental Impacts

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

miRNAs as Regulators of Antidiabetic Effects of Fucoidans

open access articleDiabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying gene expression toward up- or down-regulation. miRNAs have become compelling therapeutic targets and play crucial roles in regulating the process of insulin resistance. Fucoidan has shown potential function as an a-amylase inhibitor, which may be beneficial in the management of type 2 diabetes mellitus. In recent years, many studies on fucoidan focused on the decrease in blood glucose levels caused by ingesting low-glucose food or glucose-lowering components. However, the importance of miRNAs as regulators of antidiabetic effects was rarely recognized. Hence, this review emphasizes the antidiabetic mechanisms of fucoidan through regulation of miRNAs. Fucoidan exerts a vital antidiabetic effect by regulation of miRNA expression and thus provides a novel biological target for future research