198 research outputs found

    Comparison between two state estimation techniqueds for linear systems

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    20th World Congress of the International Federation of Automatic Control, Jul 2017, Toulouse, FranceThis paper presents a comparison in terms of accuracy and complexity between two approaches used for state estimation of linear systems: a classic Kalman filter and a guaranteed set-membership state estimation technique. The main goal of this paper is to analyze the advantages of these techniques and to combine them in the future in a new accurate and simple extension that handles system uncertainties and chance constraints. Two academic examples illustrate the main differences between the compared techniques

    A new approach for Guaranteed ellipsoidal state estimation

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    The 19th World Congress of the International Federation of Automatic Control 2014. Cape Town, SudáfricaThis paper proposes a new ellipsoid-based guaranteed state estimation approach for linear discrete-time systems with bounded perturbations and bounded measurement noise. This approach is based on the minimization of the radius of the ellipsoidal state estimation set. Firstly, the ellipsoidal state estimation is computed by off-line solving a Linear Matrix Inequality optimization problem. Secondly, a new online method is developed in order to improve the accuracy of the estimation but it leads to an increase of the online computation load. A new scaling technique is proposed to reduce the computation time, while keeping a good accuracy of the state estimation. An illustrative example is analyzed in order to show the advantages of the proposed approach

    GEOTECHNICAL AND CHEMICAL STUDY AND ANALYSIS OF THE MARBLE QUARRY IN THE ALENTEJO AREA, PORTUGAL

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    This work is a part of an economic project where the knowledge of the surface layers morphology and composed phases identification is essential for the control of any industrial process. In order to improve and increase the production, the quality and the quantity of a marble industry chain. A detailed study of the filling materials of the quarry aimed of this work has been carried out using a different, innovative, and economic methodology. With the intention to determine the nature, composition, and quality of the marble in the quarry of the Alentejo area, we proceed to many physical, mechanical tests, structural and chemical analysis. This work will be divided into two major parts which concern: i) the geotechnical study and ii) the structural and chemical analysis of the marble collect in the quarry. Geological observation and geotechnical study [1, 2] allowed us to determine the geological nature (color, size shape, and hardness),physical (mass, porosity, density and saturation coefficient) and mechanical properties (strength, impact and wear resistance tests). Chemical part [3, 4], consists in the determination of the constitution of the material including phases and elemental composition. Hence, the characterization of the material will be carried out using X-ray diffraction, X-ray fluorescence (XRF), and Energy dispersive Spectrometer (EDS). When, morphology, distribution of the formed phases and structural defects will be determined by mean of the electronic scanning microscope. This work is a part of the project "Quality Control of Ornamental Stone Blocks" with the reference ALT20-03-0247- FEDER-017659 BRO.Project "Quality Control of Ornamental Stone Blocks" with the reference ALT20-03-0247- FEDER-017659 BRO and ICT-ref a UIDB/0468

    Numerical study of eddy current by Finite Element Method for cracks detection in structures

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    In this paper, we try to use the finite element method of 2-D axisymmetry to solve problems in eddy current testing problems where the main idea is detecting crack's shape using the NDT-EC. Results are given for a simple eddy current problem using the finite element method as a tool to control cracks and defects in materials and eventually, to study their propagation as well as their shape classification. These latest can be described as the task of reconstructing the cracks and damage in a tube’s profile of an inspected specimen in order to estimate its material properties. This is accomplished by inverting eddy current probe impedance measurements which are recorded as a function of probe position. This approach has been used in the aircraft industry to control cracks. Besides, it makes it possible to highlight the defects of parts while preserving the integrity of the controlled products

    Étude phytochimique et évaluation de l’activité anti-oxydante de Thymus CIliatus ssp. Coloratus

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    Thymus ciliatus ssp. Coloratus, plante aromatique, spontanée et répandue en régions méditerranéennes et dans le nord de l’Algérie est très utilisée par les populations locales pour ses vertus médicinales. Les tests phytochimiques appliqués au Thymus ciliatus ssp coloratus ont montré la présence de quelques familles de composés chimiques et notamment les flavonoïdes. L'activité antioxydante in vitro de l’extrait de flavonoïdes a été évaluée par la technique de réduction du fer « FRAP » (ferric reducing antioxydant power) et par le test de DPPH. La première méthode a montré que la fraction acétate d’éthyle de la partie aérienne a une capacité à réduire le fer plus marquée que celles de l’acide ascorbique et le BHA et que celle des racines, est nettement inférieure. Quant aux fractions butanoliques des flavonoïdes de la partie aérienne et des racines, elles ont une capacité à réduire le fer largement inférieure à celles de l’acide ascorbique et le BHA. L’activité antioxydante, obtenue par la second procédé et relative à la fraction acétate d’éthyle des flavonoïdes de la partie aérienne de la plante est plus importante (I.C₅₀=0,85 mg/mL) que celles obtenues à partir d’antioxydants utilisés dans les industries alimentaire et pharmaceutique en l’occurrence l’acide ascorbique (I.C₅₀ = 1,12 mg/mL) et le BHA (I.C₅₀=1,61 mg/mL).Mots-clés : Thymus coloratus, activité antioxydant, flavonoïde, FRAP, DPPH.Phytochemical study and evaluation of the antioxidant activity of thymus ciliatus ssp. Coloratus Thymus ciliatus ssp. coloratus, aromatic plant, spontaneous and widespread in the Mediterranean and in northern Algeria is widely used by local people for its medicinal properties. Phytochemical tests applied for Thymus sciliatus ssp coloratus showed the presence of several families of chemical compounds including flavonoïds. The in vitro antioxidant activity of flavonoïds extract was evaluated by the iron reduction technique "FRAP" (ferric reducing antioxidant power) and DPPH test. The first method showed that the ethyl acetate fraction of the aerial part has an ability to reduce the iron greater than ascorbic acid and BHA and the roots, is significantly lower. As for butanol fractions of flavonoïds from the aerial part and roots, they have an ability to reduce iron significantly lower than those of ascorbic acid and BHA. The antioxidant activity obtained by the second method and on the ethyl acetate fraction of flavonoïds from the aerial part of the plant is more important (I.C₅₀ = 0.85 mg / mL) than those obtained from 'antioxidants used in food and pharmaceutical industries namely ascorbic acid (I.C₅₀ = 1.12 mg / mL) and BHA (I.C₅₀ = 1.61 mg / mL).Keywords : Thymus coloratus, antioxidant activity, flavonoïd, FRAP, DPPH

    Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study

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    PURPOSE: We aimed to study the association of body temperature and other admission factors with outcomes of herpes simplex encephalitis (HSE) adult patients requiring ICU admission. METHODS: We conducted a retrospective multicenter study on patients diagnosed with HSE in 47 ICUs in France, between 2007 and 2017. Fever was defined as a body temperature higher or equal to 38.3 °C. Multivariate logistic regression analysis was used to identify factors associated with poor outcome at 90 days, defined by a score of 3-6 (indicating moderate-to-severe disability or death) on the modified Rankin scale. RESULTS: Overall, 259 patients with a score on the Glasgow coma scale of 9 (6-12) and a body temperature of 38.7 (38.1-39.2) °C at admission were studied. At 90 days, 185 (71%) patients had a poor outcome, including 44 (17%) deaths. After adjusting for age, fever (OR = 2.21; 95% CI 1.18-4.16), mechanical ventilation (OR = 2.21; 95% CI 1.21-4.03), and MRI brain lesions > 3 lobes (OR = 3.04; 95% CI 1.35-6.81) were independently associated with poor outcome. By contrast, a direct ICU admission, as compared to initial admission to the hospital wards (i.e., indirect ICU admission), was protective (OR = 0.52; 95% CI 0.28-0.95). Sensitivity analyses performed after adjustment for functional status before admission and reason for ICU admission yielded similar results. CONCLUSIONS: In HSE adult patients requiring ICU admission, several admission factors are associated with an increased risk of poor functional outcome. The identification of potentially modifiable factors, namely, elevated admission body temperature and indirect ICU admission, provides an opportunity for testing further intervention strategies

    Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.

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    International audienceSHANK3 (also known as ProSAP2) regulates the structural organization of dendritic spines and is a binding partner of neuroligins; genes encoding neuroligins are mutated in autism and Asperger syndrome. Here, we report that a mutation of a single copy of SHANK3 on chromosome 22q13 can result in language and/or social communication disorders. These mutations concern only a small number of individuals, but they shed light on one gene dosage-sensitive synaptic pathway that is involved in autism spectrum disorders

    Mining and validating grape (Vitis L.) ESTs to develop EST-SSR markers for genotyping and mapping

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    Grape expressed sequence tags (ESTs) are a new resource for developing simple sequence repeat (SSR) functional markers for genotyping and genetic mapping. An integrated pipeline including several computational tools for SSR identification and functional annotation was developed to identify 6,447 EST-SSR sequences from a total collection of 215,609 grape ESTs retrieved from NCBI. The 6,447 EST-SSRs were further reduced to 1,701 non-redundant sequences via clustering analysis, and 1,037 of them were successfully designed with primer pairs flanking the SSR motifs. From them, 150 pairs of primers were randomly selected for PCR amplification, polymorphism and heterozygosity analysis in V. vinifera cvs. Riesling and Cabernet Sauvignon, and V. rotundifolia (muscadine grape) cvs. Summit and Noble, and 145 pairs of these primers yielded PCR products. Pairwise comparisons of loci between the parents Riesling and Cabernet Sauvignon showed that 72 were homozygous in both cultivars, while 70 loci were heterozygous in at least one cultivar of the two. Muscadine parents Noble and Summit had 90 homozygous SSR loci in both parents and contained 50 heterozygous loci in at least one of the two. These EST-SSR functional markers are a useful addition for grape genotyping and genome mapping

    The Complete Chloroplast Genome Sequence of Date Palm (Phoenix dactylifera L.)

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    BACKGROUND: Date palm (Phoenix dactylifera L.), a member of Arecaceae family, is one of the three major economically important woody palms--the two other palms being oil palm and coconut tree--and its fruit is a staple food among Middle East and North African nations, as well as many other tropical and subtropical regions. Here we report a complete sequence of the data palm chloroplast (cp) genome based on pyrosequencing. METHODOLOGY/PRINCIPAL FINDINGS: After extracting 369,022 cp sequencing reads from our whole-genome-shotgun data, we put together an assembly and validated it with intensive PCR-based verification, coupled with PCR product sequencing. The date palm cp genome is 158,462 bp in length and has a typical quadripartite structure of the large (LSC, 86,198 bp) and small single-copy (SSC, 17,712 bp) regions separated by a pair of inverted repeats (IRs, 27,276 bp). Similar to what has been found among most angiosperms, the date palm cp genome harbors 112 unique genes and 19 duplicated fragments in the IR regions. The junctions between LSC/IRs and SSC/IRs show different features of sequence expansion in evolution. We identified 78 SNPs as major intravarietal polymorphisms within the population of a specific cp genome, most of which were located in genes with vital functions. Based on RNA-sequencing data, we also found 18 polycistronic transcription units and three highly expression-biased genes--atpF, trnA-UGC, and rrn23. CONCLUSIONS: Unlike most monocots, date palm has a typical cp genome similar to that of tobacco--with little rearrangement and gene loss or gain. High-throughput sequencing technology facilitates the identification of intravarietal variations in cp genomes among different cultivars. Moreover, transcriptomic analysis of cp genes provides clues for uncovering regulatory mechanisms of transcription and translation in chloroplasts
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