191 research outputs found

    Interaction protocols for human-driven crisis resolution processes

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    This work aims at providing a crisis cell with process-oriented tools to manage crisis resolutions. Indeed, the crisis cell members have to define the crisis resolution process, adapt it to face crisis evolutions, and guide its execution. Crisis resolution processes are interaction-intensive processes: they not only coordinate the performance of tasks to be undertaken on the impacted world, but they also support regulatory interactions between possibly geographically distributed crisis cell members. In order to deal with such an interweaving, this paper proposes to use Interaction Protocols to both model formal interactions and ease a cooperative adaptation and guidance of crisis resolution processes. After highlighting the benefits of Interaction Protocols to support this human and collective dimension, the paper presents a protocol meta-model for their specification. It then shows how to suitably integrate specified protocols into crisis resolution processes and how to implement this conceptual framework into a service oriented architecture

    Emergent semantics in distributed knowledge management

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    Organizations and enterprises have developed complex data and information exchange systems that are now vital for their daily operations. Currently available systems, however, face a major challenge. On todays global information infrastructure, data semantics is more and more context- and time-dependent, and cannot be fixed once and for all at design time. Identifying emerging relationships among previously unrelated information items (e.g., during data interchange) may dramatically increase their business value. This chapter introduce and discuss the notion of Emergent Semantics (ES), where both the representation of semantics and the discovery of the proper interpretation of symbols are seen as the result of a selforganizing process performed by distributed agents, exchanging symbols and adaptively developing the proper interpretation via multi-party cooperation and conflict resolution. Emergent data semantics is dynamically dependent on the collective behaviour of large communities of agents, which may have different and even conflicting interests and agendas. This is a research paradigm interpreting semantics from a pragmatic prospective. The chapter introduce this notion providing a discussion on the principles, research area and current state of the art

    DNA barcodes reveal species-specific mercury levels in tuna sushi that pose a health risk to consumers

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    Excessive ingestion of mercury—a health hazard associated with consuming predatory fishes—damages neurological, sensory-motor and cardiovascular functioning. The mercury levels found in Bigeye Tuna (Thunnus obesus) and bluefin tuna species (Thunnus maccoyii, Thunnus orientalis, and Thunnus thynnus), exceed or approach levels permissible by Canada, the European Union, Japan, the US, and the World Health Organization. We used DNA barcodes to identify tuna sushi samples analysed for mercury and demonstrate that the ability to identify cryptic samples in the market place allows regulatory agencies to more accurately measure the risk faced by fish consumers and enact policies that better safeguard their health

    The future of Cybersecurity in Italy: Strategic focus area

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    This volume has been created as a continuation of the previous one, with the aim of outlining a set of focus areas and actions that the Italian Nation research community considers essential. The book touches many aspects of cyber security, ranging from the definition of the infrastructure and controls needed to organize cyberdefence to the actions and technologies to be developed to be better protected, from the identification of the main technologies to be defended to the proposal of a set of horizontal actions for training, awareness raising, and risk management

    Contemporary snapshot of tumor regression grade (TRG) distribution in locally advanced rectal cancer: a cross sectional multicentric experience.

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    Pre-operative chemoradiotherapy (CRT) followed by surgical resection is still the standard treatment for locally advanced low rectal cancer. Nowadays new strategies are emerging to treat patients with a complete response to pre-operative treatment, rendering the optimal management still controversial and under debate. The primary aim of this study was to obtain a snapshot of tumor regression grade (TRG) distribution after standard CRT. Second, we aimed to identify a correlation between clinical tumor stage (cT) and TRG, and to define the accuracy of magnetic resonance imaging (MRI) in the restaging setting. Between January 2017 and June 2019, a cross sectional multicentric study was performed in 22 referral centers of colon-rectal surgery including all patients with cT3-4Nx/cTxN1-2 rectal cancer who underwent pre-operative CRT. Shapiro-Wilk test was used for continuous data. Categorical variables were compared with Chi-squared test or Fisher's exact test, where appropriate. Accuracy of restaging MRI in the identification of pathologic complete response (pCR) was determined evaluating the correspondence with the histopathological examination of surgical specimens.In the present study, 689 patients were enrolled. Complete tumor regression rate was 16.9%. The "watch and wait" strategy was applied in 4.3% of TRG4 patients. A clinical correlation between more advanced tumors and moderate to absent tumor regression was found (p = 0.03). Post-neoadjuvant MRI had low sensibility (55%) and high specificity (83%) with accuracy of 82.8% in identifying TRG4 and pCR.Our data provided a contemporary description of the effects of pre-operative CRT on a large pool of locally advanced low rectal cancer patients treated in different colon-rectal surgical centers
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