¿Cuál es la crisis de los intelectuales en crisis? : algunos apuntes sobre la política y la cultura en el fin de siglo argentino

La ponencia en forma de apuntes, pone el foco de atención en algunas de las condiciones políticas y culturales que hicieron posible un estado del campo intelectual actual, mostrando cuáles han sido algunas de las notas salientes del debate intelectual sobre la política en los últimos años.Fil: Casco, José M.. Universidad de Buenos Aire

Diseño de servicios cuánticos a través de la especificación AsyncAPI

La computación cuántica ha evolucionado de ser una idea teórica a convertirse en una realidad tangible. Aunque no es posible acceder directamente a un ordenador cuántico de la misma manera que a los ordenadores convencionales, existen proveedores de servicios que ofrecen la posibilidad de utilizar esta tecnología. Sin embargo, estos servicios presentan ciertas limitaciones, especialmente la falta de herramientas que simplifiquen su uso y manejo. Este trabajo se enfoca en Amazon Braket, un servicio de computación cuántica ofrecido por Amazon, el cual procesa las solicitudes en colas de espera, lo que puede resultar en tiempos prolongados para obtener los resultados. Además, los resultados se almacenan en un servicio de almacenamiento proporcionado por el proveedor, lo que permite a los desarrolladores verificar el estado de las tareas cuánticas y recuperar los resultados obtenidos. No obstante, dado que el tiempo de finalización de la operación es incierto, este enfoque puede resultar ineficiente. Por lo tanto, se propone una solución alternativa que utiliza una arquitectura asíncrona e se integra con otro servicio, mediante una modificación de la especificación AsyncAPI. El objetivo es generar sistemas basados en eventos para integrar de manera programática los servicios cuánticos como parte de otros sistemas de software. Esto implica enviar el código cuántico a ejecutar al proveedor y obtener los datos resultantes de manera asíncrona.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Alternative Feeding in Iberian Pigs during Growth Period: Incorporation of Olive Cake in a Dry or Wet (silage) Form

During the last years, the high growth of the livestock production sector has caused a high demand of raw material in order to feed the animals. This higher demand has environmental consequences and a more sustainable strategy is required for livestock production. Some agro-industrial by-products such as olive cake may be beneficially used without a decrease in production traits. Here, we studied the effect of three different dietary regimens given to Iberian pigs in growing period (42 kg to 95 kg) on several growth and slaughter traits. A control standard diet group (CD) was compared with two diets based on olive by-products, one incorporating dry olive pulp in the feed (DD), and the other one incorporating olive cake in wet form (WD). This last one consisted of olive cake in a silage presentation offered ad libitum and supplemented with a specific feed given once a day in a restricted regimen as the CD and DD diets. A significantly higher average daily gain during the growing period was observed for WD diet compared with DD diet. However, this was compensated with a higher average daily gain of DD pigs during the fattening period (acorn and grass). Carcass yield was lower in DD than CD and WD pigs, but no significant differences were observed for premium cut yields, which are more important for the Iberian industry. Therefore, the diets based on olive cake does not seem to alter the growth and slaughter traits studied, however, before its implementation in feeds used for the growing period, further studies analyzing their effects on meat quality and production costs should be carried out

Local pig breeds: Nutritional requirements, innovative practices and local feeding resources as challenges in project TREASURE

TREASURE is a research and innovation project of European Union’s Horizon 2020 programme which is devoted to traditional genetic resources in pig production with aim to improve their potentials for enhanced use. Studying and improving management of local pig breeds in their production systems is one of the challenges in which we address their performances and nutrition with special attention on locally available feeding resources and innovative practices aiming to improved welfare. For that purpose 15 experiments on 12 breeds were designed in the project, which are hereafter shortly presented. Their concepts and main objectives with some highlights on already available results are described. © 2017, University of Zagreb. All rights reserved

The recycling of chromitites in ophiolites from southwestern North America

Podiform chromitites occur in mantle peridotites of the Late Triassic Puerto Nuevo Ophiolite, Baja California Sur State, Mexico. These are high-Cr chromitites [Cr# (Cr/Cr + Al atomic ratio = 0.61–0.69)] that contain a range of minor- and trace-elements and show whole-rock enrichment in IPGE (Os, Ir, Ru). That are similar to those of high-Cr ophiolitic chromitites crystallised from melts similar to high-Mg island-arc tholeiites (IAT) and boninites in supra-subduction-zone mantle wedges. Crystallisation of these chromitites from S-undersaturated melts is consistent with the presence of abundant inclusions of platinum-group minerals (PGM) such as laurite (RuS)-erlichmanite (OsS), osmium and irarsite (IrAsS) in chromite, that yield T ≈ T model ages peaking at ~ 325 Ma. Thirty-three xenocrystic zircons recovered from mineral concentrates of these chromitites yield ages (2263 ± 44 Ma to 278 ± 4 Ma) and Hf-O compositions [ɛ(t) = − 18.7 to + 9.1 and O values < 12.4‰] that broadly match those of zircons reported in nearby exposed crustal blocks of southwestern North America. We interpret these chromitite zircons as remnants of partly digested continental crust or continent-derived sediments on oceanic crust delivered into the mantle via subduction. They were captured by the parental melts of the chromitites when the latter formed in a supra-subduction zone mantle wedge polluted with crustal material. In addition, the Puerto Nuevo chromites have clinopyroxene lamellae with preferred crystallographic orientation, which we interpret as evidence that chromitites have experienced high-temperature and ultra high-pressure conditions (< 12 GPa and ~ 1600 °C). We propose a tectonic scenario that involves the formation of chromitite in the supra-subduction zone mantle wedge underlying the Vizcaino intra-oceanic arc ca. 250 Ma ago, deep-mantle recycling, and subsequent diapiric exhumation in the intra-oceanic basin (the San Hipólito marginal sea) generated during an extensional stage of the Vizcaino intra-oceanic arc ca. 221 Ma ago. The T ages at ~ 325 Ma record a partial melting event in the mantle prior to the construction of the Vizcaino intra-oceanic arc, which is probably related to the Permian continental subduction, dated at ~ 311 Ma.Funding for this research was provided through the CONACyT research project number 155662 and internal budget of the Instituto de Geología (UNAM) to AC, the Ramón y Cajal Fellowship RYC-2015-17596 to JMGJ, and by the project CGL2015-65824-P granted by the Spanish “Ministerio de Economía y Competitividad” to JAP. Additional funding for chromite microanalyses were provided by the DGAPA-UNAM postdoctoral fellowship to VC. This is also a contribution from the ARC National Key Centre for Geochemical Evolution and Metallogeny of Continents ( www.es.mq.edu.au /GEMOC) and the ARC Centre of Excellence for Core to Crust Fluid Systems. The SHRIMP facility lab and technical staff at Curtin University are also thanked for their support in the data acquisition. We also thank to Carlos Linares (Petrology Laboratory of the, UNAM, Mexico) for his help with the EMPA analyses on chromite. Michelangelo Martini, Luis Abel Jiménez-Galindo and all the personnel at the Fishermen's Cooperative Society at Bahía Tortugas (Baja California Sur) are wholeheartedly thanked for their kind assistance during our fieldwork

Acute effects of isosorbide mononitrate on circulation and the ischemic myocardium in patients with coronary artery disease

Objetivo - Avaliar, durante estudo hemodinâmico e cineangiocardiográfico, os efeitos agudos do mononitrato de isosorbitol, via sistêmica, sobre a circulação e presença de áreas viáveis de isquemia miocárdica, em portadores de cardiopatia isquêmica por aterosclerose coronária obstrutiva. Métodos - Foram estudados, durante estudo hemodinâmico e cineangiocardiográfico, 24 pacientes, 10 mulheres, com média de idade de 58 anos, portadores de cardiopatia isquêmica, em condições basais e 5min após infusão de 0,3mg/kg/peso de mononitrato de isosorbitol por via venosa, para avaliar os efeitos do medicamento sobre a circulação, o desempenho cardíaco e a motilidade segmentar do ventrículo esquerdo (VE). Resultados - Após o uso do medicamento, constatou-se redução significante da pressão média do átrio direito (p<0,01), da pressão média na artéria pulmonar (p<0,000), da pressão sistólica do VE (p<0,002), da pressão diastólica final do VE (p<0,0004), da pressão aórtica máxima (p<0,002), da pressão aórtica média (p<0,008), do volume sistólico final do VE (p<0,004) e aumento da fração de ejeção do VE (p<0,001) e da velocidade média do encurtamento circunferencial (p<0,001). Não houve modificação significante da pressão aórtica mínima, da freqüência cardíaca, do débito cardíaco e do volume diastólico final do VE. Quanto ao comportamento da motilidade segmentar, após o uso do medicamento, os 38 segmentos hipocinéticos normalizaram sua motilidade, os 4 segmentos acinéticos não se alteraram e, dos 21 segmentos discinéticos, 6 normalizaram, 8 se tornaram hipocinéticos e 7 não alteraram sua motilidade segmentar. Constatou-se ainda que o medicamento desenvolveu ação efetiva sobre a circulação, 30s após sua infusão. Conclusão - O mononitrato de isosorbide produziu ação rápida e efetiva sobre a circulação, a motilidade segmentar e desempenho do VE, identificando áreas viáveis com isquemia miocárdica.Purpose - To evaluate the acute effects of isosorbide mononitrate on circulation, cardiac function and left ventricular segmental motility in patients with isquemic heart disease due to coronary artery disease. Methods - Twenty-four patients with ischemic heart disease, 10 women, with mean age of 58 years, were studied during cardiac catheterization, at baseline condition and 5min after intravenous infusion of 0,3mg/kg of isosorbide mononitrate. Results - After infusion of isosorbide mononitrate there were significant reduction in mean right atrial pressure (p<0,01), mean pulmonary artery pressure (p<0,0001), left ventricular and diastolic pressure (p<0,004), left ventricular systolic pressure (p<0,002), maximum (p<0,002) and mean (p<0,008) aortic pressure, and left ventricular systolic volume (p<0,004), as well as significant increase in the left ventricular ejection fraction (p<0,001) and mean velocity of circunferential fibers shortening (p<0,001). There was no significant modification of minimum aortic pressure, heart rate, cardiac output nor of left ventricular and diastolic volume. With respect of segmental motility of the left ventricle after medication, 38 kypokinetic segments normalized their motility, 4 akinetic segments remained intact, and of the 21 dyskinetic segments, 6 normalized, 8 became hypokinetic and 7 remained dyskinetic. Conclusion - Isosorbide mononitrate, when used as intravenous infusion, have a rapid and direct effect on systemic and pulmonary circulation, and improving segmental motility and left ventricular performance in patients with impaired left ventricular motility caused by ischemic heart disease

Diversity across major and candidate genes in European local pig breeds

The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel employed for elucidating the genetic structure and relationships among breeds was evaluated. Most relevant genes and mutations associated with pig morphological, productive, meat quality, reproductive and disease resistance traits were prioritized and analyzed in a maximum of 47 blood samples from each of the breeds (Alentejana, Apulo-Calabrese, Basque, Bísara, Majorcan Black, Black Slavonian (Crna slavonska), Casertana, Cinta Senese, Gascon, Iberian, Krškopolje (Krškopoljski), Lithuanian indigenous wattle, Lithuanian White Old Type, Mora Romagnola, Moravka, Nero Siciliano, Sarda, Schwäbisch-Hällisches Schwein (Swabian Hall pig), Swallow-Bellied Mangalitsa and Turopolje). We successfully analyzed allelic variation in 39 polymorphisms, located in 33 candidate genes. Results provide relevant information regarding genetic diversity and segregation of SNPs associated to production and quality traits. Coat color and morphological trait-genes that show low level of segregation, and fixed SNPs may be useful for traceability. On the other hand, we detected SNPs which may be useful for association studies as well as breeding programs. For instance, we observed predominance of alleles that might be unfavorable for disease resistance and boar taint in most breeds and segregation of many alleles involved in meat quality, fatness and growth traits. Overall, these findings provide a detailed catalogue of segregating candidate SNPs in 20 European local pig breeds that may be useful for traceability purposes, for association studies and for breeding schemes. Population genetic analyses based on these candidate genes are able to uncover some clues regarding the hidden genetic substructure of these populations, as the extreme genetic closeness between Iberian and Alentejana breeds and an uneven admixture of the breeds studied. The results are in agreement with available knowledge regarding breed history and management, although largest panels of neutral markers should be employed to get a deeper understanding of the population's structure and relationships