29,196 research outputs found

    Rigidly Rotating Strings in Stationary Spacetimes

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    In this paper we study the motion of a rigidly rotating Nambu-Goto test string in a stationary axisymmetric background spacetime. As special examples we consider the rigid rotation of strings in flat spacetime, where explicit analytic solutions can be obtained, and in the Kerr spacetime where we find an interesting new family of test string solutions. We present a detailed classification of these solutions in the Kerr background.Comment: 19 pages, Latex, 9 figures, revised for publication in Classical and Quantum Gravit

    Propagation of perturbations along strings

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    A covariant formalism for physical perturbations propagating along a string in an arbitrary curved spacetime is developed. In the case of a stationary string in a static background the propagation of the perturbations is described by a wave-equation with a potential consisting of 2 terms: The first term describing the time-dilation and the second is connected with the curvature of space. As applications of the developed approach the propagation of perturbations along a stationary string in Rindler, de Sitter, Schwarzschild and Reissner-Nordstrom spacetimes are investigated.Comment: 18 pages, LaTeX, Nordita-93/17

    MHC-I genotype drives early immune selection of oncogenic mutations.

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    MHC-I exposes the intracellular contents to immune cells for surveillance of cellular health. Due to high genomic variation, individuals' immune systems differ in their ability to expose and eliminate cancer-causing mutations. These personalized immune blind spots create specific oncogenic mutation predispositions within patients and influence their prevalence across populations

    Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake

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    It has long been established that the Trypanosoma brucei TbAT1/P2 aminopurine transporter is involved in the uptake of diamidine and arsenical drugs including pentamidine, diminazene aceturate and melarsoprol. Accordingly, it was proposed that the closest Trypanosoma congolense paralogue, TcoAT1, might perform the same function in this parasite, and an apparent correlation between a Single Nucleotide Polymorphism (SNP) in that gene and diminazene tolerance was reported for the strains examined. Here, we report the functional cloning and expression of TcoAT1 and show that in fact it is the syntenic homologue of another T. brucei gene of the same Equilibrative Nucleoside Transporter (ENT) family: TbNT10. The T. congolense genome does not seem to contain a syntenic equivalent to TbAT1. Two TcoAT1 alleles, differentiated by three independent SNPs, were expressed in the T. brucei clone B48, a TbAT1-null strain that further lacks the High Affinity Pentamidine Transporter (HAPT1); TbAT1 was also expressed as a control. The TbAT1 and TcoAT1 transporters were functional and increased sensitivity to cytotoxic nucleoside analogues. However, only TbAT1 increased sensitivity to diamidines and to cymelarsan. Uptake of [3H]-diminazene was detectable only in the B48 cells expressing TbAT1 but not TcoAT1, whereas uptake of [3H]-inosine was increased by both TcoAT1 alleles but not by TbAT1. Uptake of [3H]-adenosine was increased by all three ENT genes. We conclude that TcoAT1 is a P1-type purine nucleoside transporter and the syntenic equivalent to the previously characterised TbNT10; it does not mediate diminazene uptake and is therefore unlikely to play a role in diminazene resistance in T. congolense

    Quantum integrability of quadratic Killing tensors

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    Quantum integrability of classical integrable systems given by quadratic Killing tensors on curved configuration spaces is investigated. It is proven that, using a "minimal" quantization scheme, quantum integrability is insured for a large class of classic examples.Comment: LaTeX 2e, no figure, 35 p., references added, minor modifications. To appear in the J. Math. Phy

    Bogomol'nyi Limit For Magnetic Vortices In Rotating Superconductor

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    This work is the sequel of a previous investigation of stationary and cylindrically symmetric vortex configurations for simple models representing an incompressible non-relativistic superconductor in a rigidly rotating background. In the present paper, we carry out our analysis with a generalized Ginzburg-Landau description of the superconductor, which provides a prescription for the radial profile of the normal density within the vortex. Within this framework, it is shown that the Bogomol'nyi limit condition marking the boundary between type I and type II behavior is unaffected by the rotation of the background.Comment: 7 pages, uses RevTeX, submitted to Phys.Rev.

    Search Tracker: Human-derived object tracking in-the-wild through large-scale search and retrieval

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    Humans use context and scene knowledge to easily localize moving objects in conditions of complex illumination changes, scene clutter and occlusions. In this paper, we present a method to leverage human knowledge in the form of annotated video libraries in a novel search and retrieval based setting to track objects in unseen video sequences. For every video sequence, a document that represents motion information is generated. Documents of the unseen video are queried against the library at multiple scales to find videos with similar motion characteristics. This provides us with coarse localization of objects in the unseen video. We further adapt these retrieved object locations to the new video using an efficient warping scheme. The proposed method is validated on in-the-wild video surveillance datasets where we outperform state-of-the-art appearance-based trackers. We also introduce a new challenging dataset with complex object appearance changes.Comment: Under review with the IEEE Transactions on Circuits and Systems for Video Technolog

    Critical Points in the QCD Phase Diagram with Two Flavors of Quarks

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    We employ the linear sigma model to study the chiral dynamics of two flavors of quarks at finite temperature and density. Our calculations include thermal fluctuations of both the bosonic and fermionic fields. In particular, we determine the phase diagram in the plane of temperature and baryon chemical potential as a function of the pion mass. An interesting phase structure occurs that results in zero, one, or two critical points depending on the value of the vacuum pion mass.Comment: 4 pages, Quark Matter 2009 proceeding

    Killing tensors and a new geometric duality

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    We present a theorem describing a dual relation between the local geometry of a space admitting a symmetric second-rank Killing tensor, and the local geometry of a space with a metric specified by this Killing tensor. The relation can be generalized to spinning spaces, but only at the expense of introducing torsion. This introduces new supersymmetries in their geometry. Interesting examples in four dimensions include the Kerr-Newman metric of spinning black-holes and self-dual Taub-NUT.Comment: 20 pages (a4), standard LaTeX, no figure

    The impact of hybridization on morphological variation on Xiphophorus fishes

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    Hybridization can produce novel phenotypic variation which may allow hybrid populations to evolve in novel directions relative to parentals. Hybridization can produce intermediate as well as extreme phenotypes with respect to the parent species. Furthermore, separate hybridization events may create phenotypically divergent populations compared to the parentals but also to other hybrid zones. The hybrid system of Xiphophorus birchmanni and X. malinche has been shown to be replicated independently in seven streams along an elevation gradient. The sword sexual ornament is an extension of the ventral portion of the caudal fin that has been secondarily lost in X. birchmanni but persists in X. malinche and is polymorphic in hybrids. Female X. birchmanni have lost a preference for the sword and female X. malinche and hybrids are indifferent to males with swords. To determine if these replicated hybrid zones have unique introgression of the sword, morphometric data of the parental species and hybrids were collected across the hybrid zones. Though there was a general trend for the increase of the sword as one moved towards a more X. malinche-like population, the hybrid zones displayed variation for the introgression of the sword
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