High Accuracy Correlator.

Abstract not availableJRC.H-Institute for environment and sustainability (Ispra

Computational Methods and Software Tools for Functional Analysis of miRNA Data

miRNAs are important regulators of gene expression that play a key role in many biological processes. High-throughput techniques allow researchers to discover and characterize large sets of miRNAs, and enrichment analysis tools are becoming increasingly important in decoding which miRNAs are implicated in biological processes. Enrichment analysis of miRNA targets is the standard technique for functional analysis, but this approach carries limitations and bias; alternatives are currently being proposed, based on direct and curated annotations. In this review, we describe the two workflows of miRNAs enrichment analysis, based on target gene or miRNA annotations, highlighting statistical tests, software tools, up-to-date databases, and functional annotations resources in the study of metazoan miRNAs.Junta de Andalucia PI-0173-2017 CV20.3672

Cultura organizacional del sistema empresarial de la comunidad indígena de Nuevo San Juan Parangaricutiro: un manejo sustentable forestal

Hoy, es de vital importaocia considerar los ejemplos exitosos que manejan de manera sustentable losrecursos naturales, y la Comunidad Indígena Nuevo San Juan Parangaricutlro, objeto de estudio, es un ejemplo nacional e internacional de esta práctica de aprovechamiento del recurso forestal y sus derivados, asl como de los recursos que se relacionan con éste, por ejemplo el paisaje, el agus y losfrutales, entre otros. Entonces, la pregunta que deriva este trabajo es ¿Cómo la cultura organizacional al interior del sistema productivo empresarial influye en lasformas de manejo delrecurso forestal y en el reconocimiento a escala nacional e internacional? Por ello, como objetivo a desarrollar es: mostrar la relación entre las variables de la cultura organizacional del sistema de empresas de la comunidad indígena de Nuevo San Juan Parangaricutlro, Michoacán y las formas de manejo forestal a través del análisis situacional, para lo cual se aplica un instrumento que rescata la cultura organizacional en el liderazgo, estructura orgánica funcional, comunicación, profesionalización, vinculación,formalización, innovación y tecnología

Proceedings of the ACEWATER2 Scientific Workshop Accra (Ghana) 31 Oct – 3 Nov 2016

The African Centers of Excellence on Water (ACEWATER2) project, in its second phase (2016/19), promoted by the African Ministers of Water and financed by DG DEVCO, aims at supporting the establishment of Human Capacity Development Programme of the AMCOW (African Ministers’ Council on Water) in the Water Sector, strengthens institutional networking and improving research support to policy making by scaling up the approach of the pilot phase (phase I). The main activities of the project consist in: • Strengthening of two existing NEPAD water Centers of Excellence networks in West and Southern Africa; • Expanding the NEPAD water Centres of Excellence network to Central and Eastern Africa; • Strengthening institutional networking and improving research support to policy making in the water sector; • Supporting the implementation of the African Water Ministers’ declaration urging AUC and NEPAD Centers of Excellence to develop a “Human Capacity Development Programme for junior professional and technician level capacity challenges in the water sector”; • Developing an Atlas on Regional Water Cooperation. The project geographical scope covers three major regions: Southern Africa (7 countries), Western Africa (4 countries) and Eastern/Central Africa. The project is implemented by DG JRC (overall project management and scientific cluster) with UNESCO (human capacity development cluster). Within this project, a Workshop has been organized in Accra (Ghana) from October 31st to November 3rd, specifically devoted to the sharing among CoEs of scientific interests, competences and methods towards the effective planning of (scientific) activities, achievement and delivery of scientific tools and products to support (science-based) decision making processes. By means of scientific as well as technical presentations, round tables and participative sessions, the participants (35 people representing more than 30 Institutions among Universities, Research Centres, River Basin Authorities, Regional Economic Communities and key stakeholders on water issues, further to European research Institutions as CIRAD and CREAF) shared valuable experiences and competences, including case studies, around key thematic pillars, such as: Climate Issues (Session 1), African Water-Energy-Food nexus (Session 2), Groundwater (Session 3) and Water Governance&Diplomacy (Session 4). Workshop Proceedings gather all relevant contributions in the form of (extended) abstracts and short papers, providing a general overview of key relevant issues and partners scientific interests, turning to be a valuable resource for effective planning of next project steps.JRC.D.2-Water and Marine Resource

Summary of the Proceedings of the AquaKnow E-conference on Knowledge Management for Technical Cooperation in the Water Sector in Developing Countries

In the framework of the EC project called ¿AquaKnow¿ an e-conference was organised on knowledge management for technical cooperation in the water sector in developing countries. The e-conference was organised by DG AIDCO and DG JRC and was held in June 2008. The chairman of the conference was Dr. Jay Bhagwan, Director of the Water Use and Waste Management in the Water Research Commission in South Africa. Some 145 participants from 67 organisations active in the water sector in Africa, in Europe and in Latina America participated to this e-conference. The organisations were public, private, NGOs, research and high education institutions, etc... This e-conference was an unique event to bring together an important amount of field experiences in treating the knowledge related to the water sector in the context of technical cooperation oriented to capacity building in developing countries. This technical report resumes the many ideas put on the table and extracts some of the conclusions that were used in the design and development of the Aqua know Content Management System developed by the Water4Dev team of the IES institute of the DG JRC of the European Commission.JRC.DDG.H.3-Global environement monitorin

El desarrollo profesional masculino : una perspectiva de género en la orientación profesional

En este artículo se estudian algunas de las características del proceso de desarrollo profesional masculino. Para ello, se analiza la denominada «mística mas sistema de valores que. como consecuencia del proceso de socia-culina», o el una noción de masculinidad que influye directamente en-lización, conduce a la carrera y transiciones profesionales de los hombres. Tras este análisis, las autoras dedican un apartado a la reflexión sobre la relación entre dos roles muy importantes en la vida humana: uno el que se deriva del trabajo y otro del cuidado del hogar y la familia. Finalmente, presentan una reflexión sobre la necesidad de adoptar una perspectiva de género en la intervención orientadora.________________________________ In this article some characteristics of the process of male professional development are studied. In this, the so called «Mística Masculina», or system of values that led to the notion of masculinity, as a consequence of the process of socialization, that has a direct influence on the studies and professional transitions of men. Following this analysis, the authors reflect on the relation ship between two very important roles in the human life: one from the field of employment/work, another from the care of home and family. Finally, the authors outline an argument concerning the necessity to adopt a gender persd pective in the field of orientation

Intestinal microbiota and colorectal cancer

Colorectal cancer may be influenced by changes in the intestinal microbiota that affect the mucosa and cause an immune response capable of producing inflammatory effects. Although there are still few studies in this regard, it is necessary to emphasize the need to expand the studies on this topic and to state the usefulness of the new technologies based on metagenomics.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Aplicación unidad didáctica “distancia entre dos puntos”

En el desarrollo de la Maestría en Educación Matemática (MAD3) de la Universidad de Los Andes, un grupo conformado por cuatro profesores de matemáticas diseñamos, implementamos y evaluamos la unidad didáctica denominada “Cálculo de la distancia entre dos puntos”. El diseño de la unidad didáctica se enmarca desde el análisis didáctico que se divide en cinco partes. Para el diseño tuvimos en cuenta el análisis de contenido que permite la elegir el tema, determinar la estructura conceptual, establecer los sistemas de representación, la fenomenología y documentos curriculares nacionales e institucionales en los que se involucra el tema. En segundo lugar, encontramos el análisis cognitivo mediante el cual realizamos las previsiones para el desarrollo de la unidad didáctica teniendo en cuenta la dimensión cognitiva y afectiva. En tercer lugar, tenemos el análisis de instrucción que corresponde al diseño de cada una de las tareas de aprendizaje para que se ajusten a los objetivos propuestos, a las expectativas de aprendizaje de nivel superior, las expectativas de tipo afectivo y se entrelacen por medio de la secuencia de tareas. En cuarto lugar, encontramos el análisis de actuación en el cual diseñamos los instrumentos que permiten evaluar el desarrollo de la unidad didáctica, estos instrumentos son diario del estudiante y diario del profesor. Finalmente, la evaluación de la implementación de la unidad didáctica por medio del sistema ACE4 que se alimenta de la información que se recopila de la implementación de cada una de las tareas de aprendizaje. La implementación de la unidad didáctica se llevó a cabo en el Colegio Santa Bárbara ubicado en la localidad de Ciudad Bolívar con estudiantes de grado octavo

Bayesian networks modelling in support to cross-cutting analysis of water supply and sanitation in developing countries

Despite the efforts made towards the Millennium Goals targets during the last decade, access to improved Water Supply or basic Sanitation remains still not accessible for millions of people across the World. This paper proposes a set of models that use 25 key variables from the WatSan4Dev dataset and country profiles involving Water Supply and Sanitation (Dondeynaz et al 2012). This paper proposes the use of Bayesian Network modelling methods because adapted to the management of non-normal distribution, and integrate a qualitative approach for data analysis. They also offer the advantage to integrate preliminary knowledge into the probabilistic models. The statistical performance of the proposed models ranges between 80 and 95% which is very satisfactory taking into account the strong heterogeneity of variables. Probabilistic scenarios run from the models allow a quantification of the relationships between human development, external support, governance aspects, economic activities and Water Supply and Sanitation (WSS) access. According to models proposed in this paper, a strong poverty reduction will induce an increment of the WSS access equal to 75-76% through: 1) the organisation of on-going urbanisation process to avoid slums development; and, 2) the improvement of health care for instance for children. On one side, improving governance, such as institutional efficiency, capacities to make and apply rules or control of corruption will also have a positive impact on WSS sustainable development. The first condition for an increment of the WSS access remains of course an improvement of the economic development with an increment of household income. Moreover, a significant country environmental commitment associated with civil society freedom of expression constitutes a favourable environment for sustainable WSS services delivery. Intensive agriculture through irrigation practises also appears as a mean for sustainable WSS thanks to multi-uses and complementarities. Strong and structured agriculture sector facilitates rural development in areas where WSS access often steps behind compared to urban areas . External financial support, named Official Development Aid (ODA), plays a role in WSS improvement but comes last in the sensitivity analyses of models. This aid supports first poor countries at 47%, and is associated to governance aspects: 1) political stability and 2) country environmental commitment and civil society degree of freedom. These governance aspects constitute a good framework for aid implementation in recipient countries. Modelling is run with the five groups of countries as defined in Dondeynaz et al 2012. Models for profile 4 (essential external support) and profile 5 (primary material consumption) are specifically detailed and analysed in this paper. For countries in profile 4, to fight against water scarcity and desertification pressure should be the priority. However, for countries in profile 5, efforts should first concentrate on political stability consolidation while supporting economic activity diversification. Nevertheless, for both profiles, reduction of poverty should remain the first priority as previously indicated.JRC.H.1-Water Resource

Case study of the intestinal microbiota using the XGN-MBI metagenomic assay

The microbiota of the colon and rectum is the most abundant and diverse of the human body, with a density of up to 1-2 kg of weight and a diversity that exceeds a thousand species. Metagenomics can be defined as the application of modern genomic techniques for the direct study of communities of microorganisms in their natural environment The aim of this study is to prove the usefulness of new technologies based on metagenomics, such as the XGN-MBI assay to realize gut microbiota studies.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech