Activities of the practice teaching organization and vocational teaching facilities in collaboration between the vocational school and units employing

The aim of this research is to evaluate the current level of preparation in the organization of practical training as well as the facilities that are available for practical vocational training. The collaboration in education between businesses and vocational schools is an effective strategy. As a result of the rapid transformation that has taken place in the socioeconomic context for professional skills and practical training among employees, a new educational strategy is required to address these demands in order to meet the needs of the workforce. A quantitative method was applied in this research. There were 570 individuals who were chosen at random. According to the findings, the majority of instructors and technicians possessed regulations for conducting practical teaching activities as well as suitable facilities and equipment for the purpose of vocational training. This study presents a number of suggestions for improving the standard of educational institutions as well as the professional growth opportunities available to teachers and lecturers. In addition, facility management and maintenance as well as optimize the instructional facilities and equipment are required

NGHIÊN CỨU KHẢ NĂNG HẤP THỤ CACBON CỦA RỪNG NGẬP MẶN VEN BIỂN HẢI PHÒNG

Mangrove is known as a big carbon sink in coastal areas. It is an important organic carbon source which provides for coastal ecosystems. The assessment of the carbon sequestration potential of mangrove contributes to making a scientific base for mangrove conservation and rehabilitation. In this study, the carbon sequestration of mangrove in the Hai Phong coastal areas was measured at three dominant species of mangrove Rhizophora stylosa Griff; Kandelia obovata Sheue, Liu Yong and Sonneratia caseolaris (L.) Engl. The result of the assessment was described by the net canopy photosynthesis (PN­), above and below ground biomass (AGB and BGB), and organic carbon content in sediment. The result showed that the PN ranged from 31.94 ± 1.59 tC.ha-1.yr-1 to 34.83 ± 1.95 tC.ha-1.yr-1 with the R. stylosa community being highest. Above and below ground biomass C stock ranged from 4.03 ± 0.31 t.ha-1 to 294.43 ± 24.67 t.ha-1 and from 2.38 ± 0.16 t.ha-1 to 114.16 ± 8.9 t.ha-1, respectively. S. caseolaris community had the highest biomass and R. stylosa community had the lowest biomass. The measurements of C stock in mangrove biomass for three species were R. stylosa (2.69 ± 0.19 t.ha-1); K. obovata (6.72 ± 0.34 t.ha-1) and S. caseolaris (171.61 ± 14.1 t.ha-1). The organic carbon content of sedimentscores at 10 cm depth ranged from 685.63 milligram.kg-1 of se. dry to 2676.64 milligram.kg-1 of se. dry and at 40 cm depth ranged from 937.38 milligram.kg-1 of se. dry to 2557.55 milligram.kg-1 of se. dry. The total organic carbon was stored highest in the R. stylosa community.Rừng ngập mặn là một bể chứa cacbon lớn khu vực ven biển, là một nguồn cung cấp cacbon hữu cơ quan trọng cho hệ sinh thái ven biển. Việc đánh giá khả năng hấp thụ và lưu giữ cacbon của rừng ngập mặn góp phần tạo cơ sở khoa học cho việc bảo tồn và phát triển rừng ngập mặn. Bài báo trình bày kết quả nghiên cứu khả lưu giữ cacbon của rừng ngập mặn ven biển Hải Phòng tại ba kiểu rừng đặc trưng: Đước vòi (Rhizophora stylosa Griff.); Trang (Kandelia obovata Sheue, Liu Yong) và Bần chua (Sonneratia caseolaris (L.) Engl.). Qua đó đánh giá mức độ lưu trữ cac bon qua quá trình quang hợp tán lá, sinh khối cây và trong trầm tích của ba kiểu rừng nói trên. Kết quả nghiên cứu cho thấy: lượng cacbon tích lũy qua quá trình quang hợp từ 31,94 ±          1,59 tC/ha/năm đến 34,83 ± 1,95 tC/ha/năm, trong đó cao nhất là quần xã Đước vòi (R. stylosa). Sinh khối trên (AGB) và sinh khối dưới (BGB) nằm trong khoảng tương ứng là 4,03 ± 0,31 t/ha đến 294,43 ± 24,67 t/ha và 2,38 ± 0,16 t/ha đến 114,16 ± 8,9 t/ha, Bần chua (S. caseolaris) có trữ lượng lớn nhất và thấp nhất là Đước vòi (R. stylosa). Hàm lượng cacbon hữu cơ trong trầm tích ở độ sâu 10 cm từ 685,63 mg/kg khô đến 2676,64 mg/kg khô; ở độ sâu 40 cm từ 937,38 mg/kg khô đến 2557,55 mg/kg khô, trong đó khả năng lưu trữ cacbon trong trầm tích của rừng Đước vòi (R. stylosa) là cao nhất

Evaluating model teacher education and training at Vietnam's universities of technology and education

The traditional educational paradigm has become outdated as a result of changes in both the cultural and socioeconomic setting. A more sustainable and acceptable teacher is needed in education. A quantitative study was conducted. 95 administrators and teachers at the University of Technology and Education participated in this study with the aim of analyzing the current status of the teacher education model at the institution. According to the findings of the study, the model for educator preparation has been put into practice primarily through the processes of planning, organizing and directing activities related to educator preparation as well as inspecting and assessing the quality of education. The outcomes of the study indicate that it is essential to design educational programs that are appropriate for the present context. In particular, the study suggests that one of the most important steps towards achieving success is to incorporate technology into teaching methods. The process of educating teachers with the right degree of expertise and skills should be emphasized by educators and policymakers by developing relationships with other educational institutions and allowing teachers to participate in internships

Outpatient antibiotic prescribing for acute respiratory infections in Vietnamese primary care settings by the WHO AWaRe (Access, Watch and Reserve) classification: An analysis using routinely collected electronic prescription data

Background: This study aims to investigate patterns of antibiotic prescribing and to determine patient-specific factors associated with the choice of antibiotics by the World Health Organization's Access-Watch-Reserve (WHO AWaRe) class for acute respiratory infections (ARIs) in rural primary care settings in northern Vietnam. Methods: We retrospectively reviewed health records for outpatients who were registered with the Vietnamese Health Insurance Scheme, visited one of 112 commune health centres in 6 rural districts of Nam Dinh province, Vietnam during 2019, and were diagnosed with ARIs. Patient-level prescription data were collected from the electronic patient databases. We used descriptive statistics to investigate patterns of antibiotic prescribing, with the primary outcomes including total antibiotic prescriptions and prescriptions by WHO AWaRe group. We identified patient-specific factors associated with watch-group antibiotic prescribing through multivariable logistic regression analysis. Findings: Among 193,010 outpatient visits for ARIs observed in this study, 187,144 (97.0%) resulted in an antibiotic prescription, of which 172,976 (92.5%) were access-antibiotics, 10,765 (5.6%) were watch-antibiotics, 3366 (1.8%) were not-recommended antibiotics. No patients were treated with reserve-antibiotics. The proportion of watch-antibiotic prescription was highest amongst children under 5-years old (18.1%, compared to 9.5% for 5–17-years, 4.9% for 18–49-years, 4.3% for 50–64-years, and 3.7% for 65-and-above-years). In multivariable logistic regression, children, district, ARI-type, comobid chronic respiratory illness, and follow-up visit were associated with higher likelihood of prescribing watch-group antibiotics. Interpretation: The alarmingly high proportion of antibiotic prescriptions for ARIs in primary care, and the frequent use of watch-antibiotics for children, heighten concerns around antibiotic overuse at the community level. Antimicrobial stewardship interventions and policy attention are needed in primary care settings to tackle the growing threat of antibiotic resistance

Implementation of point-of-care testing of C-reactive protein concentrations to improve antibiotic targeting in respiratory illness in Vietnamese primary care: a pragmatic cluster-randomised controlled trial

Background In previous trials, point-of-care testing of C-reactive protein (CRP) concentrations safely reduced antibiotic use in non-severe acute respiratory infections in primary care. However, these trials were done in a research-oriented context with close support from research staff, which could have influenced prescribing practices. To better inform the potential for scaling up point-of-care testing of CRP in respiratory infections, we aimed to do a pragmatic trial of the intervention in a routine care setting. Methods We did a pragmatic, cluster-randomised controlled trial at 48 commune health centres in Viet Nam between June 1, 2020, and May 12, 2021. Eligible centres served populations of more than 3000 people, handled 10–40 respiratory infections per week, had licensed prescribers on site, and maintained electronic patient databases. Centres were randomly allocated (1:1) to provide point-of-care CRP testing plus routine care or routine care only. Randomisation was stratified by district and by baseline prescription level (ie, the proportion of patients with suspected acute respiratory infections to whom antibiotics were prescribed in 2019). Eligible patients were aged 1–65 years and visiting the commune health centre for a suspected acute respiratory infection with at least one focal sign or symptom and symptoms lasting less than 7 days. The primary endpoint was the proportion of patients prescribed an antibiotic at first attendance in the intention-to-treat population. The per-protocol analysis included only people who underwent CRP testing. Secondary safety outcomes included time to resolution of symptoms and frequency of hospitalisation. This trial is registered with ClinicalTrials.gov, NCT03855215. Findings 48 commune health centres were enrolled and randomly assigned, 24 to the intervention group (n=18 621 patients) and 24 to the control group (n=21 235). 17 345 (93·1%) patients in the intervention group were prescribed antibiotics, compared with 20 860 (98·2%) in the control group (adjusted relative risk 0·83 [95% CI 0·66–0·93]). Only 2606 (14%) of 18 621 patients in the intervention group underwent CRP testing and were included in the per-protocol analysis. When analyses were restricted to this population, larger reductions in prescribing were noted in the intervention group compared with the control group (adjusted relative risk 0·64 [95% CI 0·60–0·70]). Time to resolution of symptoms (hazard ratio 0·70 [95% CI 0·39–1·27]) and frequency of hospitalisation (nine in the intervention group vs 17 in the control group; adjusted relative risk 0·52 [95% CI 0·23–1·17]) did not differ between groups. Interpretation Use of point-of-care CRP testing efficaciously reduced prescription of antibiotics in patients with non-severe acute respiratory infections in primary health care in Viet Nam without compromising patient recovery. The low uptake of CRP testing suggests that barriers to implementation and compliance need to be addressed before scale-up of the intervention. Funding Australian Government, UK Government, and the Foundation for Innovative New Diagnostics

A novel IGHMBP2 variant and clinical diversity in Vietnamese SMARD1 and CMT2S patients

BackgroundPathogenic variants in the IGHMBP2 gene are associated with two distinct autosomal recessive neuromuscular disorders: spinal muscular atrophy with respiratory distress type 1 (SMARD1; OMIM #604320) and Charcot–Marie–Tooth type 2S (CMT2S; OMIM #616155). SMARD1 is a severe and fatal condition characterized by infantile-onset respiratory distress, diaphragmatic palsy, and distal muscular weakness, while CMT2S follows a milder clinical course, with slowly progressive distal muscle weakness and sensory loss, without manifestations of respiratory disorder.MethodsWhole-exome sequencing of the IGHMBP2 gene was performed for eight Vietnamese patients with IGHMBP2-related neuromuscular disorders including five patients with SMARD1 and the others with CMT2S.ResultsWe identified one novel IGHMBP2 variant c.1574T > C (p.Leu525Pro) in a SMARD1 patient. Besides that, two patients shared the same pathogenic variants (c.1235 + 3A > G/c.1334A > C) but presented completely different clinical courses: one with SMARD1 who deceased at 8 months of age, the other with CMT2S was alive at 3 years old without any respiratory distress.ConclusionThis study is the first to report IGHMBP-2-related neuromuscular disorders in Vietnam. A novel IGHMBP2 variant c.1574T > C (p.Leu525Pro) expressing SMARD1 phenotype was detected. The presence of three patients with the same genotype but distinct clinical outcomes suggested the interaction of variants and other factors including relating modified genes in the mechanism of various phenotypes

Spatiotemporal evolution of SARS-CoV-2 Alpha and Delta variants during large nationwide outbreak of COVID-19, Vietnam, 2021

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions

Six-membered ring systems: with O and/or S atoms

A large variety of publications have emerged in 2012 involving O- and S-6- membered ring systems. The increasing number of reviews and other communica- tions dedicated to natural and synthetic derivatives and their biological significance highlights the importance of these heterocycles. Reviews on natural products involve biosynthesis and isolation of enantiomeric derivatives h12AGE4802i, biosynthesis, isolation, synthesis, and biological studies on the pederin family h12NPR980i and xanthones obtained from fungi, lichens, and bacteria h12CR3717i and on the potential chemotherapeutic value of phyto- chemical products and plant extracts as antidiabetic h12NPR580i, antimicrobial, and resistance-modifying agents h12NPR1007i. A more specific review covers a structure–activity relationship of endoperoxides from marine origin and their antitry- panosomal activity h12OBC7197i. New synthetic routes to naturally occurring, biologically active pyran derivatives have been the object of several papers. Different approaches have been discussed for the total synthesis of tetrahydropyran-containing natural products (")-zampanolide h12CEJ16868, 12EJO4130, 12OL3408i, (")-aspergillides A and B h12H(85)587, 12H(85)1255, 12TA252i, (þ)-neopeltolide h12JOC2225, 12JOC9840, 12H(85) 1255i, or their macrolactone core h12OBC3689, 12OL2346i. The total synthesis of bistramide A h12CEJ7452i and (þ)-kalihinol A h12CC901i and the stereoselec- tive synthesis of a fragment of bryostatin h12S3077, 12TL6163i have also been sur- veyed. Other papers relate the total synthesis of naturally occurring carbocyclic and heterocyclic-fused pyran compounds, such as (")-dysiherbaine h12CC6295i, penos- tatin B h12OL244i, Greek tobacco lactonic products, and analogues h12TL4293i and on the structurally intriguing limonoids andhraxylocarpins A–E h12CEJ14342i. The stereocontrolled synthesis of fused tetrahydropyrans was used in the preparation of blepharocalyxin D h12AGE3901i. Polyphenolic heterocyclic compounds have also received great attention in 2012. The biological activities and the chemistry of prenylated caged xanthones h12PCB78i, the occurrence of sesquiterpene coumarins h12PR77i, and the medicinal properties of the xanthone mangiferin h12MRME412i have been reviewed. An overview on the asymmetric syntheses of flavanones and chromanones h12EJO449i, on the synthesis and reactivity of flavones h12T8523i and xanthones h12COC2818i, on the synthesis and biosynthesis of biocoumarins h12T2553i, and on the synthesis and applications of flavylium compounds h12CSR869i has been discussed. The most recent developments in the synthesis and applications of sultones, a very important class of sulfur compounds, were reported h12CR5339i. A review on xanthene-based fluorescent probes for sensing cations, anions, bio- logical species, and enzyme activity has described the spiro-ring-opening approach with a focus on the major mechanisms controlling their luminescence behavior h12CR1910i. The design and synthesis of other derivatives to be used as sensors of gold species h12CC11229i and other specific metal cations h12PC823i have also been described. Recent advances related to coumarin-derived fluorescent chemosen- sors for metal ions h12COC2690i and to monitoring in vitro analysis and cellular imaging of monoamine oxidase activity h12CC6833i have been discussed. The study of various organic chromophores allowed the synthesis of novel dica- tionic phloroglucinol-type bisflavylium pigments h12SL2053i, and the optical and spectroscopic properties of several synthetic 6-aryldibenzo[b,d]pyrylium salts were explored h12TL6433i. Discussion of specific reactions leading to O- and S-membered heterocyclic compounds covers intramolecular radical cyclization h12S2475i and asymmetric enamine and dienamine catalysis h12EJO865i, oxa-Michael h12CSR988i and dom- ino Knoevenagel–hetero-Diels–Alder (hDA) reactions h12T5693i, and the versatility in cycloadditions as well as nucleophilic reactions using o-quinones h12CSR1050i. The use of specific reagents relevant to this chapter includes molecular iodine h12CEJ5460, 12COS561i, samarium diiodide–water for selective reductive transfor- mations h12CC330i, o-quinone methides as versatile intermediates h12CEJ9160i, InCl3 as catalyst h12T8683i, and gold and platinum p-acid mediated insertion of alkynes into carbon–heteroatom s-bonds h12S3401i. The remainder of this chapter discusses the most studied transformations on O- and S-6-membered heterocycles