The effects of rotator cuff tear on shoulder proprioception

Purpose: To evaluate the effects of rotator cuff tear (RCT) and its severity on shoulder proprioception. Methods: We studied 132 consecutive patients (67 M-65 F; mean age ± SD, 66.03 ± 9.04; range, 43–78) who underwent arthroscopic rotator cuff repair. Tear size was determined intra-operatively. The control group included 82 subjects (38 M-44 F; mean age ± SD, 65.87 ± 8.06; range, 41–75) with no RCT. All participants, wearing an eye mask, were submitted to the evaluation of the joint position sense (JPS) at 30°, 60°, 90°, 120°, and 150° of shoulder forward flexion during the sitting position, using a digital inclinometer securely attached to the subject’s arm using hook-and-loop straps. The passive placement and active replacement method was used; the order of the tested angles was randomly selected. The entire test was repeated three times. The error score, by averaging the three trials, was measured as the absolute difference between the target angle and the observed angle. Statistics were performed. Results: The intraclass correlation coefficient for all degrees of flexion movement measured was > 0.90, exhibiting a very high correlation. We found significant differences between cases and controls regarding the results of joint position sense error at all measurements (p < 0.05). According to RCT size, we found significant differences between groups at 30° (F = 27.27, p < 0.001), 90° (F = 5.37, p = 0.006), 120° (F = 10.76, p < 0.001), and 150° (F = 30.93, p < 0.001) of shoulder flexion; in details, patients with massive RCT showed greater absolute error value than those with both small and large RCT at 30°, 90°, 120°, and 150° of shoulder flexion (p < 0.05). Conclusions: RCT provokes an alteration of shoulder proprioception, evaluated as the loss of joint position sense, and the impairment is related to tear severity

Doing Philanthropy at the Time of the Sustainable Development Goals: The Case of Fondazione Compagnia di San Paolo

This article outlines how strategic philanthropy can align its mission with the United Nations 2030 Agenda for Sustainable Development by describing the experience of the most important foundation of banking origin in Italy. Fondazione Compagnia di San Paolo marked a milestone in 2020 in aligning with the Agenda, applying the Sustainable Development Goals as a rigorous, internationally shared methodological framework and restructuring its operations to focus on three programmatic efforts — Planet, People, and Culture — aligned with those goals. To complete our examination of this transformation, we conducted a benchmark analysis involving nine case studies of foundations in Europe and the United States to identify the level of engagement and convergence of each with the 2030 Agenda framework. This article begins with an introduction to the topic of sustainability in the philanthropic sector, which is followed by a case study of the Compagnia di San Paolo’s path to adoption of the framework. It then measures the impact of its activities through quantitative indicators, highlighting the foundation’s transformation, and concludes with a comparison between Compagnia di San Paolo’s approaches and some international best practices to provide a better understanding of our long-term positioning in the international context

Preliminary validation of the Italian version of the original sport motivation scale

Candela, F., Zucchetti, G., & Villosio, C. (2014). Preliminary validation of the Italian version of the original Sport Motivation Scale. J. Hum. Sport Exerc., 9(1), pp.136-147. This study aims at develop and validate a preliminary Italian version of the original Sport Motivation Scale. The original scale was translated into Italian following transcultural procedures. The scale was administered to 228 athletes (55% females, n = 125, M age= 25, SD= 13) recruited in an Italian Sports Medicine Center. Confirmatory factor, internal consistency and correlation analysis among subscales were performed. Gender differences and associations between SMS subscales and psychological variables (coach leadership style, sport enjoyment, self-confidence in sport, attitude toward doping behaviors) were investigated. The analysis showed encouraging results about the validity and reliability of the Italian version of the SMS scale. Key words: MOTIVATION, SPORT MOTIVATION SCALE, ITALIAN VALIDATION

italian early adolescent females intrinsic motivation in sport an explorative study of psychological and sociorelational correlates

Abstract Using self-determination theory (SDT), this study simultaneously investigated the relationships between intrinsic motivation, psychological factors (sport enjoyment, social self-efficacy), and sociorelational factors (perceived coaching behaviors) by subsequently testing whether psychological factors mediate the relationships between social-relational factors and intrinsic motivation. One hundred and twentyseven early adolescent females from several teams of the Italian Volleyball Society completed a self-report questionnaire. Results showed that female athletes' intrinsic motivation was associated with a) sport enjoyment and b) perceived coaching behaviors (e.g., training and instruction, social support). Second, results showed that training-and-instruction coaches' leadership style affected intrinsic motivation via the females' enjoyment in sport. This study provided further insights into unknown associations among psychological, sociorelational factors and intrinsic motivation, highlighting the innovative role of sport enjoyment as a key factor for sustaining intrinsic motivation. Original and useful behavioral suggestions will be given to the coaches in order to sustain female athletes' sport enjoyment and their intrinsic motivation

RecO-mediated DNA homology search and annealing is facilitated by SsbA

Bacillus subtilis RecO plays a central role in recombinational repair and genetic recombination by (i) stimulating RecA filamentation onto SsbA-coated single-stranded (ss) DNA, (ii) modulating the extent of RecA-mediated DNA strand exchange and (iii) promoting annealing of complementary DNA strands. Here, we report that RecO-mediated strand annealing is facilitated by cognate SsbA, but not by a heterologous one. Analysis of non-productive intermediates reveals that RecO interacts with SsbA-coated ssDNA, resulting in transient ternary complexes. The self-interaction of ternary complexes via RecO led to the formation of large nucleoprotein complexes. In the presence of homology, SsbA, at the nucleoprotein, removes DNA secondary structures, inhibits spontaneous strand annealing and facilitates RecO loading onto SsbA–ssDNA complex. RecO relieves SsbA inhibition of strand annealing and facilitates transient and random interactions between homologous naked ssDNA molecules. Finally, both proteins lose affinity for duplex DNA. Our results provide a mechanistic framework for rationalizing protein release and dsDNA zippering as coordinated events that are crucial for RecA-independent plasmid transformation