An iterative design method for Coalitional control networks with constraints on the shapley Value

9th World CongressThe International Federation of Automatic ControlCape Town, South Africa. August 24-29In this work, we introduce a new iterative design method for a coalitional control scheme for linear systems recently proposed. In this scheme, the links in the network infrastructure are enabled or disabled depending on their contribution to the overall system performance. As a consequence, the local controllers are divided dynamically into sets or coalitions that cooperate in order to attain their control tasks. The new design method allows the control system designer to include new constraints regarding the game theoretical tools of the control architecture, while optimizing the matrices that define the controller

Potencial pedagógico del Mobile Learning en el aula de música en secundaria

El presente estudio, basado en el proyecto musical nacido en el Centro de Formación del Profesorado de Castilla la Mancha en 2013, Crea la Banda Sonora de tu vida, pretende demostrar cómo el uso de dispositivos móviles en el aula de música en Secundaria, tiene un enorme potencial pedagógico y educativo, tomando como referencia las actuales metodologías educativas, como son las inteligencias múltiples, la inteligencia emocional, el trabajo colaborativo o el Mobile Learning, desde el aprendizaje por proyectos, el emprendimiento o la integración del modelo TPACK, desde una perspectiva relacional, proponiendo un modelo de enseñanza-aprendizaje que utilice adecuadamente el Mobile Learning. El uso generalizado en su vida cotidiana de dispositivos móviles en la población estudiada, alumnado de Secundaria, nos obliga en cierta medida a incorporarlos a la escuela, con una base metodológica adecuada, relacionando educación formal, informal y no formal, utilizando el Mobile Learning como una estrategia de aprendizaje, adscrita a la competencia de aprender a aprender y a las demás competencias del s. XXI.

An Application of Cooperative Game Theory to Distributed Control

18th World CongressThe International Federation of Automatic ControlMilano (Italy) August 28 - September 2, 2011In this paper we propose to study the underlying properties of a given distributed control scheme in which a set of agents switch between different communication strategies that define which network links are used in order to regulate to the origin a set of unconstrained linear systems. The problems of how to decide the time-varying communication strategy, share the benefits/costs and detect which are the most critical links in the network are solved using tools from game theory. The proposed scheme is demonstrated through a simulation example

NMR Spectroscopy Study of New Imidamide Derivatives as Nitric Oxide Synthase Inhibitors

En este artículo científico se describe la determinación espectroscópica inequívoca mediante Resonancia Magnética Nuclear de una serie de nuevos inhibidores de la Óxido Nítrico Sintasa con estructura de aril- y heteroaril-imidamidaVicerrectorado de Política Científica e Investigación de la Universidad de Granad

The influence of sulfuric environments on concretes elaborated with sulfate resistant cements and mineral admixtures. Part 1: Concrete exposed to Sodium Sulfate (Na2SO4) = Estudio de la influencia de los medios con presencia de sulfatos en hormigones con cementos sulforresistentes y adiciones minerales. Parte 1: Hormigones expuestos a sulfato sódico (Na2SO4)

The study of sulfate attack in concrete is considered vital for the preservation of the structural integrity of constructions. Its aggressive behaviour causes degradation of the cement matrix which changes the initial properties of the material. In this article, the sulfate resistance of concrete is studied. To that goal, four different concrete mixes were made with sulphur resistant cement. The concretes were tested for compressive strength, transport capacity of sulfates and microstructural properties. An experimental program was proposed in which the concrete samples were submerged in sodium sulphate (Na2SO4) solution. The obtained results were compared with reference values of concretes cured in calcium hydroxide [Ca(OH)2]. According to the results the concrete with ground granulated blast-furnace slag presented the best behavior when exposed to sodium sulphate (Na2SO4) solution. El estudio del ataque de sulfatos en el hormigón se considera de gran importancia para la conservación de la integridad estructural de las construcciones. Su agresividad se basa en la degradación de la matriz cementicia modificando las características iniciales de diseño. En el presente trabajo se estudia la resistencia del hormigón al ataque de sulfatos provenientes de sulfato sódico (Na2SO4). Para llevar a cabo la investigación se diseñaron cuatro dosificaciones de hormigón empleando cementos sulforresistentes y adiciones minerales. Se llevó a cabo una propuesta experimental donde las muestras de hormigón se sumergieron en disolución de sulfato sódico (Na2SO4) de concentración 1M. Posteriormente se realizaron ensayos de resistencia mecánica, capacidad de transporte de sulfatos y propiedades microestructurales, a distintas edades. Los resultados obtenidos se compararon con valores de referencia de mezclas de hormigón curadas expuestas a hi-dróxido cálcico [Ca(OH)2]. De acuerdo a los resultados obtenidos, el hormigón con escoria de alto horno presentó las mejores características de durabilidad frente a sulfatos provenientes de sulfato sódic

The influence of sulfuric environments on concretes elaborated with sulfate resistant cements and mineral admixtures. Part 2: Concrete exposed to Magnesium Sulfate (MgSO4) = Estudio de la influencia de los medios con presencia de sulfatos en hormigones con cementos sulforresistentes y adiciones minerales. Parte 2.Hormigones expuestos a sulfato magnésico (MgSO4)

The present work studies the resistant of the concrete against magnesium sulfate (MgSO4) and compare the results with values obtained previously of the same concretes exposed to sodium sulfate (Na2SO4). Thus, it is possible analyze the influence of the cation type. To that end, four different concrete mixes were made with sulfur resistant cement and mineral admixtures (silica fume, fly ash and blast furnace slag). The concretes were submerged for different period in magnesium sulfate (MgSO4). After that, different tests were carried out to define mechanical and microstructural properties. The results obtained were compared with reference values of concretes cured in calcium hydroxide [Ca(OH)2]. According to the results, the concrete with blast furnace slag presented the best behavior front MgSO4, meanwhile the concretes with silica fume and fly ash were the most susceptible. The resistance of the concrete with blast furnace slag could be attributed to the characteristics of the hydrated silicates formed during the hydration time, which include aluminum in the chemical chain that hinder its chemical decomposition during the attack of magnesium. The magnesium sulfate solution was most aggressive than sodium sulfate solution. El presente trabajo estudia la resistencia de hormigones al ataque de sulfatos provenientes de sulfato magnésico (MgSO4) y compara estos valores con resultados previos de los mismos hormigones atacados con sulfato sódico (Na2SO4). De esta manera se estudia la interacción del catión que acompaña al ion sulfato durante su afectación a la matriz cementicia. Para lo anterior, se diseñaron cuatro dosificaciones empleando cementos sulforresistentes y adiciones minerales (humo de sílice, ceniza volante y escoria de alto horno). Los hormigones se sumergieron, por distintos periodos de tiempo, en disolución de sulfato magnésico (MgSO4) de concentración 1M, para después realizarles ensayos mecánicos y a nivel microestructural. Los valores obtenidos se compararon con los obtenidos en el hormigón de referencia curado en hidróxido cálcico. El hormigón con escoria de alto horno presentó el mejor comportamiento frente a MgSO4, siendo las mezclas de humo de sílice y ceniza volante las más susceptibles. La resistencia del hormigón con escoria se atribuye a las características de los silicatos hidratados formados durante la hidratación, los cuales incorporan aluminio en las cadenas impidiendo su descomposición ante un ataque por magnesio. El medio con sulfato magnésico mostro una mayor agresividad que el medio con sulfato sódico

Evaluation of impact-shock on gait after the implementation of two different training programs in older adults

Gait is negatively affected with increasing age. It is widely accepted that training produces physical-functional improvements in older adults, which can be assessed with numerous physical-functional tests. However, very few studies have been carried out using accelerometry to analyse the training effect on kinetic and kinematic variables in older adults, and there is no one that investigate the effects of two different training programs. Therefore, the aim of this study is to analyse the effects of an interval-walking program and a multicomponent program on the acceleration impacts, shock attenuation, step-length, stride frequency, and gait speed in older adults. Methods: 23 participants were divided into multicomponent training group [n = 12, 7 female, 71.58 (4.56) years] and interval-walking group [n = 11, 6 female, 69.64 (3.56) years]. We evaluated the participants using three triaxial accelerometers, placing one on the distal end of each tibia and one on the forehead. Findings: After 14 weeks' of training, the maximum acceleration values both for the head accelerometer and for the non-dominant tibia, as well as the attenuation in the same leg, increased in the multicomponent training group. The maximum acceleration values for the head and the stride frequency also increased in the intervalwalking group. Lower limb strength improved in both groups. Interpretation: Given the benefits we found for each of these programs, we encourage their consideration when planning older adults training programs and suggest that multicomponent programs should be introduced prior to the start of walking-based programs

Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors.

This work was supported by the grant from Comisión Interministerial de Ciencia y Tecnología, Ministerio de Economía y competitividad (MINECO) (SAF2017-84894-R), with funds from the European Union, and by the Ministerio de Economia y Competitividad, Instituto de Salud Carlos III (CIBER-CV).The authors also thank the Centro de Supercomputación de la Universidad de Granada (CSIRC) for the computing resources and the Granada University Library for the financial support to the APC.In search of new Nitric Oxide Synthase (NOS) inhibitor agents, two isosteric series of derivatives with an imidamide scaffold (one of them with a hydroxyl group and the other with a carbonyl one) were synthesized and evaluated on inducible (iNOS) and neuronal (nNOS) isoforms. These compounds have been designed by combining a kynurenamine framework with an amidine moiety in order to improve selectivity for the inducible isoform. In general, the in vitro inhibitory assays exhibited better inhibition values on the iNOS isoform, being the N-(3-(2-amino-5-methoxyphenyl)-3-hydroxypropyl)-4-(trifluoromethyl)benzimidamide 4i the most active inhibitor with the highest iNOS selectivity, without inhibiting eNOS. Docking studies on the two most active compounds suggest a different binding mode on both isozymes, supporting the experimentally observed selectivity towards the inducible isoform. Physicochemical in silico studies suggest that these compounds possess good drug-likeness properties.CSIRCCentro de Supercomputación de la Universidad de GranadaGranada University LibraryEuropean CommissionMinisterio de Economía y Competitividad SAF2017-84894-RInstituto de Salud Carlos IIIComisión Interministerial de Ciencia y Tecnologí

A game theoretical randomized method for large-scale systems partitioning

© 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.In this paper, a game theory-based partitioning algorithm for large-scale systems (LSS) is proposed. More specifically, a game over nodes is introduced in a model predictive control framework. The Shapley value of this game is used to rank the communication links of the control network based on their impact on the overall system performance. A randomized method to estimate the Shapley value of each node and also an efficient redistribution of the resulting value to the links involved are considered to relieve the combinatorial explosion issues related to LSS. Once the partitioning solution is obtained, a sensitivity analysis is proposed to give a measure of its performance. Likewise, a greedy fine tuning procedure is considered to increase the optimality of the partitioning results. The full Barcelona drinking water network (DWN) is analyzed as a real LSS case study showing the effectiveness of the proposed approach in comparison with other partitioning schemes available in the literature.Peer ReviewedPostprint (author's final draft

Um estudo descritivo dos resultados obstétricos e neonatais em dois modelos de assistência ao parto em primíparas

Introduction: In the 20th century, childbirth went from being attended at home to the hospital setting. Inappropriate and unnecessary interventions were uncritically adopted, leading to a dehumanization of childbirth. This is the model that currently exists in most Spanish hospitals, which has been questioned by the World Health Organization as early as 1996. Objective: The aim is to describe the differences in obstetrical and neonatal results across two different models of maternity care (biomedical model and humanised birth). Method: A correlational descriptive and multicenter study was carried out. A convenience sample of 205 primiparous women, 110 biomedical model and 95 humanised model, were recruited. Obstetrical and neonatal results were compared in two hospitals with different models of maternity care in Spain. Results: The humanised model of maternity care produces better obstetrical outcomes (spontaneous beginning of labour, normal vaginal birth, intact perineum and I degree tear and less episiotomies) than the biomedical model. There were no differences in neonatal outcomes. Conclusion: The benefits of implementing a humanised model of delivery care should be considered by health policy makers and reflected in the woman and her baby.Introducción: En el siglo XX el parto pasó de ser atendido en casa al ámbito hospitalario. Se adoptaron de forma acrítica intervenciones inapropiadas e innecesarias que condujeron a una deshumanización del parto. Este es el modelo que existe actualmente en la mayoría de los hospitales españoles y que fue cuestionado por la OMS ya en 1996. Objetivo: Describir las diferencias que existen en los resultados obstétricos y neonatales en primíparas en dos modelos distintos de asistencia al parto (biomédico y humanizado). Método: Se llevó a cabo un estudio descriptivo, de corte transversal. Se obtuvo una muestra por conveniencia de 205 primíparas, 110 del modelo biomédico y 95 del humanizado. Se compararon los resultados obstétricos y neonatales en dos hospitales con modelos diferentes de asistencia al parto en España. Resultados: En el modelo humanizado de asistencia al parto se obtuvieron unos mejores resultados obstétricos (inicio espontáneo, parto eutócico, periné íntegro o desgarro de I grado y menos episiotomías) que en el biomédico. No hubo diferencias en los resultados neonatales. Conclusión: Los beneficios de instaurar un modelo humanizado de asistencia al parto deberían ser considerados por los responsables de políticas sanitarias y reflejados en la mujer y su criatura.Introdução: No século XX, o parto deixou de ser realizado em casa para ser realizado no ambiente hospitalar. Intervenções inadequadas e desnecessárias foram adotadas acriticamente, levando a uma desumanização do parto. Este é o modelo que existe atualmente na maioria dos hospitais espanhóis e que foi questionado pela Organização Mundial da Saúde já em 1996. Objetivo: O objetivo principal desse estudo é descrever as diferenças existentes nos resultados obstétricos e neonatais em primíparas em dois modelos distintos de assistência ao parto (biomédico e humanizado). Método: Foi realizado um estudo descritivo, transversal. Obteve-se uma amostra por conveniência de 205 primíparas, 110 do modelo biomédico e 95 do modelo humanizado. Os resultados obstétricos e neonatais foram comparados em dois hospitais com diferentes modelos de assistência ao parto na Espanha. Resultados: No modelo humanizado de assistência ao parto obtiveram-se melhores resultados obstétricos (início espontâneo, parto eutócico, períneo íntegro ou laceração grau I e menos episiotomias) do que no modelo biomédico. Não houve diferença nos resultados neonatais. Conclusão: Os benefícios da implementação de um modelo humanizado de assistência ao parto devem ser considerados pelos formuladores de políticas de saúde e refletidos na mulher e em seu bebê