104 research outputs found

    Interpreting the Labour Party: Approaches to Labour politics and history

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    Interpreting the Labour Party consists of twelve essays on some of the principal thinkers and schools of thought concerned with the political and historical development of the Labour Party and the wider labour movement. It examines the major methodologies and approaches in Labour studies and critically evaluates much of the most interesting scholarship in this area of study. The essays are written by contributors who have devoted many years to the study of the Labour Party, the trade union movement and the various ideologies associated with them. The collection begins with chapters that examine Labour's ideological journey and assess the impact of the "new political history" on views of the party. Later contributions focus on how the problematic concept of "Labourism" has been applied to the party by the New Left and analyse how Labour's union link has been conceptualised. Key thinkers analysed include Henry Pelling, Ross McKibbin, Ralph Miliband, Lewis Minkin, David Marquand, Perry Anderson and Tom Nairn. Each chapter situates its subject matter in the context of a broader intellectual legacy, including the works of Sidney and Beatrice Webb, Theodore Rothstein, Stuart Hall and Samuel Beer, among others. The book will be of interest to undergraduate students of British politics and political theory, and to academics concerned with Labour politics and history, trade union history and politics, research methodology and political analysis

    Looming struggles over technology for border control

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    New technologies under development, capable of inflicting pain on masses of people, could be used for border control against asylum seekers. Implementation might be rationalized by the threat of mass migration due to climate change, nuclear disaster or exaggerated fears of refugees created by governments. We focus on taser anti-personnel mines, suggesting both technological countermeasures and ways of making the use of such technology politically counterproductive. We also outline several other types of ‘non-lethal’ technology that could be used for border control and raise human rights concerns: high-powered microwaves, armed robots, wireless tasers, acoustic devices/vortex rings, ionizing and pulsed energy lasers, chemical calmatives, convulsants, bioregulators and malodurants. Whether all these possible border technologies will be implemented is a matter for speculation, but their serious human rights implications warrant advance scrutiny

    Making data a first class scientific output : data citation and publication by NERC's Environmental Data Centres

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    The NERC Science Information Strategy Data Citation and Publication project aims to develop and formalise a method for formally citing and publishing the datasets stored in its environmental data centres. It is believed that this will act as an incentive for scientists, who often invest a great deal of effort in creating datasets, to submit their data to a suitable data repository where it can properly be archived and curated. Data citation and publication will also provide a mechanism for data producers to receive credit for their work, thereby encouraging them to share their data more freely

    DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.

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    Loss-of-function mutations in DJ-1 (PARK7) gene account for about 1% of all familial Parkinson's disease (PD). While its physiological function(s) are not completely clear, DJ-1 protects neurons against oxidative stress in both in vitro and in vivo models of PD. The molecular mechanism(s) through which DJ-1 alleviates oxidative stress-mediated damage remains elusive. In this study, we identified Paraoxonase-2 (PON2) as an interacting target of DJ-1. PON2 activity is elevated in response to oxidative stress and DJ-1 is crucial for this response. Importantly, we showed that PON2 deficiency hypersensitizes neurons to oxidative stress induced by MPP+ (1-methyl-4-phenylpyridinium). Conversely, over-expression of PON2 protects neurons in this death paradigm. Interestingly, PON2 effectively rescues DJ-1 deficiency-mediated hypersensitivity to oxidative stress. Taken together, our data suggest a model by which DJ-1 exerts its antioxidant activities, at least partly through regulation of PON2

    Enhancing public service innovation through value co-creation: capacity building and the 'innovative imagination’

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    This article considers how a perspective on value co-creation, known as ‘service-dominant logic’ (S-D logic), contributes to theoretical and empirical understandings of the processes underlying social innovation and co-creation in public services. Specifically, this explores how adopting a service ecosystems perspective to interpret empirical data regarding participation experiences in a UK public service innovation programme, enhances understanding of learning and knowledge exchange processes, experimentation and value co-creation in public service innovation projects

    Final report on project SP1210: Lowland peatland systems in England and Wales – evaluating greenhouse gas fluxes and carbon balances

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    Lowland peatlands represent one of the most carbon-rich ecosystems in the UK. As a result of widespread habitat modification and drainage to support agriculture and peat extraction, they have been converted from natural carbon sinks into major carbon sources, and are now amongst the largest sources of greenhouse gas (GHG) emissions from the UK land-use sector. Despite this, they have previously received relatively little policy attention, and measures to reduce GHG emissions either through re-wetting and restoration or improved management of agricultural land remain at a relatively early stage. In part, this has stemmed from a lack of reliable measurements on the carbon and GHG balance of UK lowland peatlands. This project aimed to address this evidence gap via an unprecedented programme of consistent, multi year field measurements at a total of 15 lowland peatland sites in England and Wales, ranging from conservation managed ‘near-natural’ ecosystems to intensively managed agricultural and extraction sites. The use of standardised measurement and data analysis protocols allowed the magnitude of GHG emissions and removals by peatlands to be quantified across this heterogeneous data set, and for controlling factors to be identified. The network of seven flux towers established during the project is believed to be unique on peatlands globally, and has provided new insights into the processes the control GHG fluxes in lowland peatlands. The work undertaken is intended to support the future development and implementation of agricultural management and restoration measures aimed at reducing the contribution of these important ecosystems to UK GHG emissions

    On the variability of cold region flooding

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    Cold region hydrological systems exhibit complex interactions with both climate and the cryosphere. Improving knowledge on that complexity is essential to determine drivers of extreme events and to predict changes under altered climate conditions. This is particularly true for cold region flooding where independent shifts in both precipitation and temperature can have significant influence on high flows. This study explores changes in the magnitude and the timing of streamflow in 18 Swedish Sub-Arctic catchments over their full record periods available and a common period (1990-2013). The Mann-Kendall trend test was used to estimate changes in several hydrological signatures (e.g. annual maximum daily flow, mean summer flow, snowmelt onset). Further, trends in the flood frequency were determined by fitting an extreme value type I (Gumbel) distribution to test selected flood percentiles for stationarity using a generalized least squares regression approach.Results highlight shifts from snowmelt-dominated to rainfall-dominated flow regimes with all significant trends (at the 5% significance level) pointing toward (1) lower magnitudes in the spring flood; (2) earlier flood occurrence; (3) earlier snowmelt onset; and (4) decreasing mean summer flows. Decreasing trends in flood magnitude and mean summer flows suggest widespread permafrost thawing and are supported by increasing trends in annual minimum daily flows. Trends in selected flood percentiles showed an increase in extreme events over the full periods of record (significant for only four catchments), while trends were variable over the common period of data among the catchments. An uncertainty analysis emphasizes that the observed trends are highly sensitive to the period of record considered. As such, no clear overall regional hydrological response pattern could be determined suggesting that catchment response to regionally consistent changes in climatic drivers is strongly influenced by their physical characteristics

    Evaluation of Mental Health First Aid from the Perspective Of Workplace End UseRs—EMPOWER: protocol of cluster randomised trial phase

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    Background: Mental Health First Aid (MHFA) is a mental health intervention that teaches people how to identify, understand and help someone who may be experiencing a mental health issue. Reviews of the implementation of MHFA found between 68 and 88% of trained Mental Health First Aiders had used their skills when in contact with someone experiencing mental health difficulties. Reviews evaluating the impact of MHFA suggest positive outcomes. However, to date, there has been no systematic, rigorous evaluation of the impact of MHFA on recipients of the intervention, the organisations providing it and the cost-effectiveness of MHFA overall. This trial will evaluate the effectiveness and cost-effectiveness of MHFA. Methods: The study is a multi-centred, two-arm clustered randomised controlled trial. Organisations will be randomly allocated to the control or intervention (estimated sample size 800 recipients). The intervention is the standard MHFA intervention provided by Mental Health First Aid England (MHFAE). The control condition will be organisations having a brief consultation from MHFAE on promoting mental health and well-being in the workplace. The primary outcome is health seeking behaviour, measured using the Actual Help Seeking Questionnaire, at 6 months’ follow-up. Data collection will be undertaken at baseline (T0), post-intervention—up to 3 months (T1), at 6 months (T2), 12 months (T3) and 24 months (T4). The primary analysis will be conducted on those participants who receive MHFA, a per protocol analysis. Discussion: The study is the first to evaluate the effect of MHFA in the workplace on employees with direct and indirect experience of the intervention, when compared with usual practice. Being also the first to assess, systematically, the social impact of MHFA and investigate its cost-effectiveness adds to the originality of the study. The study promises to yield important data, as yet unknown, regarding the effectiveness, cost-effectiveness, implementation issues, and the sustainability of MHFA in the workplace
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