64 research outputs found
Anion templates in synthesis and dynamic combinatorial libraries
- Author
- AV Eliseev
- B Hasenknopf
- B Hasenknopf
- C Reuter
- C Reuter
- C Seel
- CS Campos-Fernandez
- CS Campos-Fernandez
- D Meshcheryakov
- DH Busch
- DK Chand
- EA Katayev
- EA Katayev
- EA Katayev
- GA Melson
- GM Hubner
- H Amouri
- H Amouri
- J-M Lehn
- J-M Lehn
- J-M Lehn
- JA Wisner
- JS Fleming
- M Bru
- M Roitzsch
- MC Thompson
- MCT Fyfe
- MD Lankshear
- MD Lankshear
- MR Sambrook
- N Gimeno
- P Diaz
- PT Corbett
- R Vilar
- R Vilar
- R Vilar
- RL Paul
- S Anderson
- S Otto
- S Otto
- S Otto
- SJ Rowan
- SJ Rowan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2008
- Field of study
HIV patients stable on ART retain evidence of a high CMV load but changes to Natural Killer cell phenotypes reflect both HIV and CMV
- Author
- AA Bashirova
- C Campos
- CA Almeida
- CS Wagner
- D Heiden
- DB Tan
- DS Bae
- DW Hendricks
- G Alter
- G Alter
- I Helantera
- Jacinta Montgomery
- Jacquita S. Affandi
- JF Lima
- JS Affandi
- KL Springer
- L Azzoni
- L Berg
- M Cooper
- MJ Revilleza
- MR Goodier
- N Khan
- N Romo
- NK Bjorkstrom
- P Price
- Patricia Price
- PY Hsue
- Q Ouyang
- RL Ownby
- S Fernandez
- S Lopez-Verges
- Silvia Lee
- SJ Brunt
- TW Kuijpers
- WD Docke
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Background: Whilst ART corrects many effects of HIV disease, T cell populations retain features of accelerated immunological aging. Methods: Here we analyse phenotypic changes to natural killer (NK) cells in HIV patients who began ART with <200 CD4 T-cells/µl and maintained virological control for 12-17 years, compared with CMV seropositive and seronegative healthy control donors. Results: Humoral responses to CMV antigens (lysate, gB, IE-1) remain elevated in the patients (P <0.0001) despite the long duration of ART. Patient's NK cells responded poorly to K562 cells when assessed by CD107a and IFNγ, but this could not be attributed to CMV as responses were low in CMV-seronegative controls. Moreover HIV (and not CMV) increased expression of CD57 on CD56lo cells. Conclusions: Comparisons with published studies suggest that CMV accelerates age-related increases in CD57 expression but levels plateau by 60-70 years of age, so the effect of CMV disappears. In HIV patients the plateau is higher and perhaps reached sooner
Molecular characterization of hepatitis B virus X gene in chronic hepatitis B patients
- Author
- A Kay
- AS Lok
- BC Song
- Belen Bouzas
- C Grandjacques
- C Kreutz
- CM Chu
- CS Choi
- CT Yeh
- D Posada
- DL Swofford
- FB Hollinger
- GG Chen
- H Sumi
- H Yotsuyanagi
- I Chemin
- JD Thompson
- K Kidd-Ljunggren
- K Kidd-Ljunggren
- K Kidd-Ljunggren
- K Koike
- Luciana Barbini
- Luciana Tadey
- M Lindh
- M Lindh
- M Mizokami
- MM Ledesma
- MR Brunetto
- N Kawabe
- N Shinkai
- P Arauz-Ruiz
- P Leone FG
- PP Scaglioni
- R Jardi
- Rodolfo Campos
- S Datta
- S Gunther
- S Locarnini
- SC Pezzano
- Silvina Fernandez
- SP Tong
- TF Baumert
- V Venard
- VE Buckwold
- WN Chen
- Y Tanaka
- ZL Fang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/07/2012
- Field of study
BACKGROUND: HBV-X protein is associated with the pathogenesis of HBV related diseases, specially in hepatocellular carcinomas of chronic patients. Genetic variability of the X gene includes genotypic specific variations and mutations emerging during chronic infection. Its coding sequence overlaps important regions for virus replication, including the basal core promoter. Differences in the X gene may have implications in biological functions of the protein and thus, affect the evolution of the disease. There are controversial results about the consequences of mutations in this region and their relationship with pathogenesis. The purpose of this work was to describe the diversity of HBV-X gene in chronic hepatitis patients infected with different genotypes, according to liver disease. METHODS: HBV-X gene was sequenced from chronic hepatitis B patient samples, analyzed by phylogeny and genotyped. Nucleotide and aminoacid diversity was determined calculating intragenetic distances. Mutations at 127, 130 and 131 aminoacids were considered in relation to liver disease. RESULTS: The most prevalent genotype detected in this cohort was F (F1 and F4), followed by D and A. Most of the samples corresponding to genotypes A and F1 were HBeAg(+) and for genotypes D and F4, HBeAg(−) samples were represented in a higher percentage. Intragenetic distance values were higher in HBeAg(−) than in positive samples for all genotypes, and lower in overlapped regions, compared to single codification ones. Nucleotide and aminoacid diversities were higher in HBeAg(−), than in HBeAg(+) samples. CONCLUSIONS: Independently of the infecting genotypes, mutations at any of 127, 130 and/or 131 aminoacid positions and HBeAg(−) status were associated with mild liver disease in this cohort
TRY plant trait database - enhanced coverage and open access
- Author
- Aakala T
- Abedi M
- Acosta ATR
- Adamidis GC
- Adamson K
- Aiba M
- Albert CH
- Alcantara JM
- Alcazar CC
- Aleixo I
- Ali H
- Amiaud B
- Ammer C
- Amoroso MM
- Anand M
- Anderson C
- Anh TDL
- Anten N
- Antos J
- Apgaua DMG
- Ashman TL
- Asmara DH
- Asner GP
- Aspinwall M
- Atkin O
- Aubin I
- Baastrup-Spohr L
- Bahalkeh K
- Bahn M
- Baker T
- Baker WJ
- Bakker JP
- Baldocchi D
- Baltzer J
- Banerjee A
- Baranger A
- Barlow J
- Barneche DR
- Baruch Z
- Bastianelli D
- Battles J
- Bauerle W
- Bauters M
- Bazzato E
- Beckmann M
- Beeckman H
- Beierkuhnlein C
- Bekker R
- Belfry G
- Belluau M
- Beloiu M
- Benavides R
- Benomar L
- Berdugo-Lattke ML
- Berenguer E
- Bergamin R
- Bergmann J
- Berner L
- Bernhardt-Romermann M
- Bigler C
- Bjorkman AD
- Blackman C
- Blanco C
- Blonder B
- Blumenthal D
- Bocanegra-Gonzalez KT
- Boeckx P
- Bohlman S
- Bohning-Gaese K
- Boisvert-Marsh L
- Bond W
- Bond-Lamberty B
- Bonisch G
- Boom A
- Boonman CCF
- Bordin K
- Boughton EH
- Boukili V
- Bowman DMJS
- Bravo S
- Brendel MR
- Broadley MR
- Brown KA
- Bruelheide H
- Brumnich F
- Bruun HH
- Bruy D
- Buchanan SW
- Bucher SF
- Buchmann N
- Buitenwerf R
- Bunker DE
- Burger J
- Burrascano S
- Burslem DFRP
- Butterfield BJ
- Byun C
- Caccianiga M
- Cadotte M
- Cailleret M
- Camac J
- Camarero JJ
- Campany C
- Campetella G
- Campos JA
- Cano-Arboleda L
- Canullo R
- Carbognani M
- Carlucci MB
- Carvalho F
- Casanoves F
- Castagneyrol B
- Catford JA
- Cavender-Bares J
- Cerabolini BEL
- Cervellini M
- Chacon-Madrigal E
- Chapin FS
- Chapin K
- Chelli S
- Chen AP
- Chen SC
- Cherubini P
- Chianucci F
- Choat B
- Chung KS
- Chytry M
- Ciccarelli D
- Coll L
- Collins CG
- Conti L
- Coomes D
- Cornelissen JHC
- Cornwell WK
- Corona P
- Coyea M
- Craine J
- Craven D
- Cromsigt JPGM
- Csecserits A
- Cufar K
- Cuntz M
- da Silva AC
- Dahlin KM
- Dainese M
- Dalke I
- Dalle Fratte M
- Danihelka J
- Dannoura M
- Dawson S
- de Beer AJ
- de Dios VR
- De Frutos A
- de Gasper AL
- De Long JR
- Dechant B
- Delagrange S
- Delpierre N
- Derroire G
- Dias AS
- Diaz S
- Diaz-Toribio MH
- Dimitrakopoulos PG
- Dobrowolski M
- Doktor D
- Domingues TF
- Dong N
- Dransfield J
- Dressler S
- Drevojan P
- Duarte L
- Ducouret E
- Dullinger S
- Durka W
- Duursma R
- Dymova O
- E-Vojtko A
- Eckstein RL
- Ejtehadi H
- Elser J
- Emilio T
- Engemann K
- Erfanian MB
- Erfmeier A
- Esquivel-Muelbert A
- Esser G
- Estiarte M
- Fagan WF
- Fagundez J
- Falster DS
- Fan Y
- Fang JY
- Farris E
- Fazlioglu F
- Feng YH
- Fernandez-Mendez F
- Ferrara C
- Ferreira J
- Fidelis A
- Finegan B
- Firn J
- Flowers TJ
- Flynn DFB
- Fontana V
- Forey E
- Forgiarini C
- Francois L
- Frangipani M
- Frank D
- Frenette-Dussault C
- Freschet GT
- Fry EL
- Fyllas NM
- Gachet S
- Gallagher R
- Ganade G
- Ganga F
- Garcia-Palacios P
- Gargaglione V
- Garnier E
- Garrido JL
- Garvizu GS
- Gea-Izquierdo G
- Gibson D
- Gillison AN
- Giroldo A
- Glasenhardt MC
- Gleason S
- Gliesch M
- Goldberg E
- Goldel B
- Gonzalez-Akre E
- Gonzalez-Andujar JL
- Gonzalez-Melo A
- Gonzalez-Robles A
- Graae BJ
- Granda E
- Graves S
- Green WA
- Gregor T
- Gross N
- Guerin GR
- Gunther A
- Gutierrez AG
- Haddock L
- Haines A
- Hall J
- Hambuckers A
- Han WX
- Harrison SP
- Hattingh W
- Hawes JE
- He PC
- He TH
- Heberling JM
- Helm A
- Hempel S
- Hentschel J
- Herault B
- Heres AM
- Herz K
- Heuertz M
- Hickler T
- Hietz P
- Higuchi P
- Hipp AL
- Hirons A
- Hock M
- Hogan JA
- Holl K
- Honnay O
- Hornstein D
- Hou EQ
- Hough-Snee N
- Hovstad KA
- Ichie T
- Igic B
- Illa E
- Isaac M
- Ishihara M
- Ivanov L
- Ivanova L
- Iversen CM
- Izquierdo J
- Jackson B
- Jackson RB
- Jactel H
- Jagodzinski AM
- Jandt U
- Jansen S
- Jenkins T
- Jentsch A
- Jespersen JRP
- Jiang GF
- Johansen JL
- Johnson D
- Jokela EJ
- Joly CA
- Jordan GJ
- Joseph GS
- Junaedi D
- Junker RR
- Justes E
- Kabzems R
- Kane J
- Kaplan Z
- Kattenborn T
- Kattge J
- Kavelenova L
- Kearsley E
- Kempel A
- Kenzo T
- Kerkhoff A
- Khalil MI
- Kinlock NL
- Kissling WD
- Kitajima K
- Kitzberger T
- Kjoller R
- Klein T
- Kleyer M
- Klimesova J
- Klipel J
- Kloeppel B
- Klotz S
- Knops JMH
- Kohyama T
- Koike F
- Kollmann J
- Komac B
- Komatsu K
- Konig C
- Kraft NJB
- Kramer K
- Kreft H
- Kuhn I
- Kumarathunge D
- Kuppler J
- Kurokawa H
- Kurosawa Y
- Kuyah S
- Laclau JP
- Lafleur B
- Lallai E
- Lamb E
- Lamprecht A
- Larkin DJ
- Laughlin D
- Lavorel S
- Le Bagousse-Pinguet Y
- le Maire G
- le Roux E
- le Roux PC
- Leadley P
- Lee T
- Lens F
- Lewis SL
- Lhotsky B
- Li XE
- Li YZ
- Lichstein JW
- Liebergesell M
- Lim JY
- Lin YS
- Linares JC
- Liu CJ
- Liu DJ
- Liu U
- Livingstone S
- Llusia J
- Lohbeck M
- Lopez-Garcia A
- Lopez-Gonzalez G
- Lososova Z
- Louault F
- Lukacs BA
- Lukes P
- Luo YJ
- Lussu M
- Ma SY
- Mack M
- Maire V
- Makela A
- Makinen H
- Malhado ACM
- Mallik A
- Manning P
- Manzoni S
- Marchetti Z
- Marchino L
- Marcilio-Silva V
- Marcon E
- Marignani M
- Markesteijn L
- Marques M
- Martin A
- Martinez-Garza C
- Martinez-Vilalta J
- Maskova T
- Mason K
- Mason N
- Massad TJ
- Masse J
- Mayrose I
- Mazzochini GG
- McCarthy J
- McCormack ML
- McCulloh K
- McFadden IR
- McGill BJ
- McPartland MY
- Medeiros JS
- Medlyn B
- Meerts P
- Mehrabi Z
- Meir P
- Melo FPL
- Mencuccini M
- Meredieu C
- Messier J
- Meszaros I
- Metsaranta J
- Michaletz ST
- Michelaki C
- Migalina S
- Milla R
- Miller JED
- Minden V
- Ming R
- Mokany K
- Moles AT
- Molnar VA
- Molofsky J
- Molz M
- Montgomery RA
- Monty A
- Moravcova L
- Moreno-Martinez A
- Moretti M
- Mori AS
- Mori S
- Morris D
- Morrison J
- Mucina L
- Mueller S
- Muir CD
- Muller SC
- Munoz F
- Myers-Smith IH
- Myster RW
- Nagano M
- Naidu S
- Narayanan A
- Natesan B
- Negoita L
- Nelson AS
- Neuschulz EL
- Ni J
- Niedrist G
- Nieto J
- Niinemets U
- Nolan R
- Nottebrock H
- Nouvellon Y
- Novakovskiy A
- Nystuen KO
- O'Grady A
- O'Hara K
- O'Reilly-Nugent A
- Oakley S
- Oberhuber W
- Ohtsuka T
- Oliveira R
- Ollerer K
- Olson ME
- Onipchenko V
- Onoda Y
- Onstein RE
- Ordonez JC
- Osada N
- Ostonen I
- Ottaviani G
- Otto S
- Overbeck GE
- Ozinga WA
- Pahl AT
- Paine CET
- Pakeman RJ
- Papageorgiou AC
- Parfionova E
- Partel M
- Patacca M
- Paula S
- Paule J
- Pauli H
- Pausas JG
- Peco B
- Penuelas J
- Perea A
- Pereira CMR
- Peri PL
- Petisco-Souza AC
- Petraglia A
- Petritan AM
- Phillips OL
- Pierce S
- Pillar VD
- Pinho BX
- Pisek J
- Pomogaybin A
- Poorter H
- Portsmuth A
- Poschlod P
- Potvin C
- Pounds D
- Powell AS
- Power SA
- Prentice IC
- Prinzing A
- Puglielli G
- Pysek P
- Raevel V
- Rammig A
- Ransijn J
- Ray CA
- Reich PB
- Reichstein M
- Reid DEB
- Rejou-Mechain M
- Ribeiro S
- Richardson S
- Riibak K
- Rillig MC
- Riviera F
- Robert EMR
- Roberts S
- Robroek B
- Roddy A
- Rodrigues AV
- Rogers A
- Rollinson E
- Rolo V
- Romermann C
- Ronzhina D
- Roscher C
- Rosell JA
- Rosenfield MF
- Rossi C
- Roy DB
- Royer-Tardif S
- Ruger N
- Ruiz-Peinado R
- Rumpf SB
- Rusch GM
- Ryo M
- Sack L
- Saldana A
- Salgado-Negret B
- Salguero-Gomez R
- Santa-Regina I
- Santacruz-Garcia AC
- Santos J
- Sardans J
- Scalon MC
- Schamp B
- Scherer-Lorenzen M
- Schleuning M
- Schmid B
- Schmidt M
- Schmitt S
- Schneider JV
- Schowanek SD
- Schrader J
- Schrodt F
- Schuldt B
- Schurr F
- Semchenko M
- Seymour C
- Sfair JC
- Sharpe JM
- Sheppard CS
- Sheremetiev S
- Shiodera S
- Shipley B
- Shovon TA
- Siebenkas A
- Sierra C
- Silva M
- Silva V
- Sitzia T
- Sjoman H
- Slot M
- Smith NG
- Sodhi D
- Soltis D
- Soltis P
- Somers B
- Sonnier G
- Sorensen MV
- Sosinski EE
- Soudzilovskaia NA
- Souza AF
- Spasojevic M
- Sperandii MG
- Stan AB
- Stegen J
- Steinbauer K
- Stephan JG
- Sterck F
- Stojanovic DB
- Strydom T
- Suarez ML
- Svenning JC
- Svitkova I
- Svitok M
- Svoboda M
- Swaine E
- Swenson N
- Tabarelli M
- Takagi K
- Tappeiner U
- Tarifa R
- Tarin T
- Tautenhahn S
- Tauugourdeau S
- Tavsanoglu C
- te Beest M
- Tedersoo L
- Thiffault N
- Thom D
- Thomas E
- Thompson K
- Thornton PE
- Thuiller W
- Tichy L
- Tissue D
- Tjoelker MG
- Tng DYP
- Tobias J
- Torok P
- Torres-Ruiz JM
- Tothmeresz B
- Treurnicht M
- Trivellone V
- Trolliet F
- Trotsiuk V
- Tsakalos JL
- Tsiripidis I
- Tysklind N
- Umehara T
- Usoltsev V. A.
- Vadeboncoeur M
- Vaezi J
- Valderrama MY
- Valladares F
- Vamosi J
- van Bodegom PM
- van Breugel M
- Van Cleemput E
- van de Weg M
- van der Merwe S
- van der Plas F
- van der Sande MT
- van Kleunen M
- Van Meerbeek K
- Vanderwel M
- Vanselow KA
- Varhammar A
- Varone L
- Vassilev K
- Vellend M
- Veneklaas EJ
- Verbeeck H
- Verheyen K
- Vibrans A
- Vieira I
- Villacis J
- Violle C
- Vivek P
- Wagner K
- Waldram M
- Waldron A
- Walker AP
- Waller M
- Walther G
- Wang F
- Wang H
- Wang WQ
- Watkins H
- Watkins J
- Weber U
- Weedon JT
- Wei LP
- Weigelt P
- Weiher E
- Wells AW
- Wellstein C
- Wenk E
- Werner GDA
- Westoby M
- Westwood A
- White PJ
- Whitten M
- Williams M
- Winkler DE
- Winter K
- Wirth C
- Womack C
- Wright IJ
- Wright J
- Wright SJ
- Ximenes F
- Yamada T
- Yamaji K
- Yanai R
- Yankov N
- Yguel B
- Zanini KJ
- Zanne AE
- Zeleny D
- Zhao YP
- Zheng J
- Zheng JM
- Zieminska K
- Zirbel CR
- Zizka G
- Zo-Bi IC
- Zotz G
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/01/2020
- Field of study
Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
Polyatomic anion versus acetonitrile in coordinating ability: structural properties of AgX-bearing 1,4-bis(2-isonicotinoyloxyethyl)piperazine (X− = NO3 −, CF3SO3 −, ClO4 −, BF4 −, and PF6 −)
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- Abellán AN
- Abellán AN
- Abellán AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- Alcázar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- Alegría L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
- Almudevar PM
- Almudévar PM
- Altıntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
- Amor LL
- Amorim V
- Anand RK
- Andersen LW
- Andersson S
- Andoh K
- Andrade AH
- Andrade AH
- Andrade AH
- Andrade G
- Andreis DT
- Andreis DT
- Annane D
- Antonelli M
- Antoniadou A
- Antonio C
- Antonucci E
- Antón DG
- Anzueto A
- Appiani F
- Aquevedo A
- Aragon C
- Araujo NJ
- Araujo VF
- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
- Arias CC
- Arias N
- Arias-Verdu MD
- Arias-Verdu MD
- Arias-Verdu MD
- Armaganidis A
- Arora MK
- Arora N
- Arrigo M
- Arslantas MK
- Artiguenave M
- Aslanian P
- Aspide R
- Asyralyyeva G
- Ataman S
- Ataman S
- Atchade E
- Atchade E
- Atchasiri S
- Athapattu P
- Atkins G
- Aublanc M
- Aublanc M
- Augustin P
- Augustin P
- Auquier P
- Avilés-Jurado FX
- Avramidis V
- Ayala LY
- Aydin M
- Azevedo JC
- Azevedo JR
- Aznar GP
- Babalis D
- Babini G
- Bachli EB
- Bader A
- Bader A
- Baena J
- Baidya DK
- Baikova VN
- Bakker J
- Balcázar LC
- Balcázar LC
- Baldassarri R
- Baldwin CE
- Balik M
- Ball I
- Ballin A
- Balsera B
- Banderas-Bravo ME
- Banderas-Bravo ME
- Bandert A
- Bangstad IL
- Baptista N
- Baquero JD
- Barbadillo S
- Barberet G
- Barberet G
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- Cariou A
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- Carmona AF
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- Carratalá A
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- Carreño R
- Carvalho JP
- Carvalho KV
- Casals XN
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- Castellanos A
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- Castillo-Lorente E
- Castillo-Lorente E
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- Chernyshuk S
- Chevret S
- Chhor V
- Chiang CC
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- Chiou KR
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- Chiu LC
- Chiumello D
- Chiurazzi C
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- Cho Y
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- Choi YY
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- Chou W
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- Christopher KB
- Chrétien JM
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- Colombo A
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- Combes A
- Concha P
- Connolly B
- Constan A
- Constan A
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- Conti G
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- Cordón J
- Corona A
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- Corzo L
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- Cui N
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- Curiel-Balsera E
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- Curtis A
- Cuthbertson BH
- Cutuli SL
- Câmara M
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- da Silva VZ
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- Dalhuisen A
- Dalorzo M
- Damas P
- Dambrosio M
- Damås JK
- Das Neves A
- David H
- Davis C
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- Day A
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- De Backer A
- De Brito-Ashurst I
- De Cassai A
- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
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- De Pascale G
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- De Sanctis F
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- De Sousa I
- de Vera AP
- de Wilde W
- De Zani D
- Deblier I
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- Del Arco A
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- Del Rosario CG
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- Elbers PW
- Elgendy M
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- Engelberts D
- ENVIN-HELICS Study Group
- Erb J
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- Eroles AA
- Escalada SH
- Escalada SH
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- Escribá A
- Escórcio S
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- Espinasse F
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- Fernández IF
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- Ferri F
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- Filipe E
- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
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- Floccard B
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- FROG ICU Investigators
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- GETGAG Working Group
- GETGAG/SEMICYUC
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- González-Jiménez AI
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- Hung WT
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- Hung WT
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- Ignacio ML
- Iida A
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- Imanaka H
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- Ince C
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- IPREA Study Group
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- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
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- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
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- Jensen JU
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- Jeong IY
- Jeong WY
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- Jiao LR
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- Joachim J
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- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
- Judickas S
- Juez A
- Juliarena A
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- Jun IG
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- Jung KW
- Junior JM
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- Kaminsky GE
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- Kara A
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- Katabami K
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- Kim HJ
- Kim JM
- Kim JM
- Kim JW
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- Knafelj R
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- Ko SB
- Kobayashi A
- Koco E
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- Kodate A
- Kodate A
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- Kolnikova I
- Komuro T
- Kondili E
- Kongpolprom N
- Kooner G
- Kostalas M
- Kosuk ME
- Kotsopoulos A
- Kou PS
- Kouatchet A
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- Kox M
- Kraegpoeth A
- Krenn CG
- Krishna B
- Kristof J
- Kruger A
- Kruger A
- Krüger A
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- Ku NS
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- Kubota K
- Kuebler WM
- Kulaga EV
- Kulkarni AP
- Kumari BK
- Kumbamu A
- Kunze-Szikszay N
- Kurmukov IA
- Kurth T
- Kurtz P
- Kurtz P
- Kwon HM
- Kwon HM
- Kwon WY
- Kwon WY
- Kwon WY
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- Kyle UG
- Kyle UG
- Labaune MA
- Labra C
- Lacerda P
- Laerkner E
- Lafaurie M
- Lafuente E
- Lagonidis D
- Lagos R
- Lahmer T
- Lai CC
- Lai CH
- Lake K
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- Lapteva K
- Larsson JS
- Latini R
- Latini R
- Latini R
- Latorre J
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- Lau YH
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- Lauretta MP
- Laureys S
- Lavrentieva A
- Lawrence N
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- Lee WY
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- Leitao AL
- Leite RT
- Leonard H
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- Lheureux O
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- Liao X
- Lichtenstein D
- Lim TH
- Limuti R
- Lin KC
- Lin KC
- Lin KC
- Lin KC
- Lin KL
- Lin PH
- Lin SC
- Lin SC
- Lin SC
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- Lin WC
- Lin WC
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- Lischinsky A
- Lissonde F
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- Liu CP
- Liu CP
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- Llorente B
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- Lobo-Civico A
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- Lombardo MD
- Londoño JG
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- Lortat-Jacob B
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- Lotay R
- Loudet CI
- Louf-Durier A
- Louf-Durier A
- Louis B
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- Lozano JA
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- Lucinio NM
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- Lukaszewicz AC
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- Ly H
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- López AR
- López L
- López MA
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- MacKay A
- MacKay A
- Mackey G
- Mackey G
- MacPhee I
- Macrì M
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- Maekawa K
- Maekawa K
- Maekawa K
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- Maghsoudi B
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- Marcos-Zambrano LJ
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- Martín-Loeches I
- Martínez F
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- Martínez MV
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- Mejías CR
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- Melo N
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- Menendez R
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- Mercat A
- Mercat A
- Mergulhão PJ
- Merino-Vega D
- Messenger D
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- Midwinter MJ
- Mignot T
- Miguelena PR
- Mihara Y
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- Okayama Research Investigation Organizing Network (ORION)investigators
- Olaechea P
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- Olivares F
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- Oobayashi W
- Orden VA
- Ori C
- Orlando A
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- Philips BJ
- Phongpagdi P
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- Prazeres PH
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- Rood PJ
- Ros Martínez J
- Rosario LE
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- Rossini P
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- Sabetian G
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- Struijs A
- Stubbs C
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- Suchomel P
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- Tabatabaei HR
- Tabei SH
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- Taccone FS
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- Tapponnier R
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- Temprano-Gómez I
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- Tjepkema-Cloostermans MC
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- Tofiño AL
- Toh CH
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- Tomas E
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- WIND study group
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- Yang JS
- Yang YL
- Yasuda H
- Yatabe T
- Yebenes JC
- Yeh YC
- Yemets H
- Yergaliyeva A
- Yılmaz G
- Yilmazer F
- Yodice P
- Yokoyama M
- Yonis H
- Yonis H
- Yonis H
- Yoon SZ
- Yoruk F
- Yoshida K
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
- Zahorec M
- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
- Zeroual N
- Zerva L
- Zhang J
- Zhou JC
- Zhou JC
- Zhou JX
- Zhovnir V
- Zibandah N
- Zijlstra F
- Zimmerman J
- Zogheib E
- Zogheib E
- Zogheib E
- Zullino V
- Zwaag J
- Zýková I
- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
- Author
- Ab Majid MA
- Ab Rahman AS
- Ab Rahman R
- Abayasinghe C
- Abbott T
- Abdullah NH
- Abdur-Rahman L
- Abeloos J
- Abernethy C
- Abidin UN
- Abrunhosa A
- Absar M
- Adam S
- Adams D
- Adams G
- Adamson M
- Adekola O
- Adelaja Y
- Ademola A
- Adenekan A
- Adenike O
- Adeolu AA
- Adetoye A
- Adewale B
- Adigun T
- Adolfsson A
- Aflori L
- Africander C
- Afshari A
- Agarwal V
- Agodirin O
- Aguero Vera M
- Aguzzoli C
- Ahmad A
- Ahmad N
- Ahmad T
- Ahmad T
- Ahmad Y
- Ahmed A
- Ahmed J
- Ai Y
- Aignatoaie M
- Aimoniotou-Georgiou E
- Akanmu O
- Akerman N
- Akinwale M
- Akring I
- Al 'Amri K
- Al Anizi M
- Al hussaini S
- Al-Soudaine Y
- Aladin H
- Alagbe-Briggs O
- Alaman Laguarda G
- Albaj S
- Alcock D
- Alcock L
- Aldecoa C
- Aldecoa C
- Aleixo FB
- Alexander H
- Alexander M
- Alexander-Sefre F
- Alherz F
- Ali H
- Ali M
- Ali S
- Alias A
- Alias AH
- Alias RLR
- Alit MA
- Allen S
- Allen SJ
- Allison J
- Alloj C
- Allorto NL
- Allsop J
- Almeida W
- Alonso E
- Alphonsus C
- Alvares D
- Alves MJ
- Amador JCB
- Ameer Y
- Amendola CP
- Ami N
- Amstrup-Hansen L
- Anagnou A
- Andersen C
- Anderson C
- Anderson C
- Anderson F
- Anderson P
- Andreadaki E
- Andreou A
- Andreou P
- Andrew A
- Andrews E
- Angermair S
- Angus K
- Anillo V
- Antal O
- Antill P
- Antoniadou E
- Antonina W
- Apagaki E
- Apostolou K
- Applewhaite C
- Aquino LPG
- Ar P
- Arawwawala D
- Ardern D
- Argue R
- Arkalaki E
- Armaganidis A
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- Armstrong R
- Arnaoutoglou C
- Arnaoutoglou E
- Arnold G
- Arrandale L
- Arrich J
- Arrigo M
- Arshad H
- Arshad MA
- Arumugam S
- Arustei M
- Arvaniti K
- Arya A
- Arya S
- Asimakos A
- Asudo F
- Athanasakis E
- Atiku M
- Attrill E
- Attwood C
- Auer P
- Avidan M
- Avila Sanchez FJ
- Avila EJD
- Avis J
- Awad H
- Axioti E
- Ayyaz H
- Azam UAA
- Azambuja P
- Azevedo C
- Aziz FZ
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- Chlorou D
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- Dumitrascu CO
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- Whysall K
- Wibrandt I
- Wickboldt N
- Wickenhauser R
- Wid WM
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- Xu G-J
- Xu L
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- Xu Q
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- Xue R
- Yagnik A
- Yan Y
- Yang J
- Yang L
- Yang Q
- Yang S
- Yang T
- Yang Y
- Yao S
- Yao Y
- Yap HL
- Yarwood J
- Yassaee A
- Ye H
- Ye H
- Yegnaram S
- Yeh E
- Yin N
- Yip CP
- Yong J
- Yu HC
- Yu S
- Yu T
- Yu Y
- Yuan D
- Yuan F
- Yuan J
- Yuan J
- Yuan Y
- Yuliana A
- Zaimi D
- Zakynthinos S
- Zamudio D
- Zangrillo A
- Zapata DDM
- Zbitnew G
- Zeidan L
- Zeng Q
- Zerman L
- Zettergren J
- Zhang B
- Zhang E
- Zhang H
- Zhang H
- Zhang H
- Zhang J
- Zhang K
- Zhang L
- Zhang M
- Zhang M
- Zhang Q
- Zhang R
- Zhang S
- Zhang W
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhao B
- Zhao B
- Zhao C
- Zhao J
- Zhao J
- Zhao L
- Zhao L
- Zhao S
- Zhao T
- Zhao W
- Zhao W
- Zhao X
- Zhen J
- Zheng K
- Zheng L
- Zheng T
- Zhong Y
- Zhou C
- Zhou D
- Zhou H
- Zhou H
- Zhou J
- Zhou J
- Zhou J
- Zhou X-J
- Zhu X
- Zhu X
- Zhu Y
- Zhu Z
- Zhuang X
- Zilis G
- Zin NHM
- Zingerle N
- Zingg U
- Zoerner F
- Zonneveldt H
- Zou X
- Zoulamoglou M
- Zsisku L
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
TRY plant trait database - enhanced coverage and open access
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- Aakala T
- Abedi M
- Acosta ATR
- Adamidis GC
- Adamson K
- Aiba M
- Albert CH
- Alcantara JM
- Alcazar CC
- Aleixo I
- Ali H
- Amiaud B
- Ammer C
- Amoroso MM
- Anand M
- Anderson C
- Anh TD-L
- Anten N
- Antos J
- Apgaua DMG
- Ashman T-L
- Asmara DH
- Asner GP
- Aspinwall M
- Atkin O
- Aubin I
- Baastrup-Spohr L
- Bahalkeh K
- Bahn M
- Baker T
- Baker WJ
- Bakker JP
- Baldocchi D
- Baltzer J
- Banerjee A
- Baranger A
- Barlow J
- Barneche DR
- Baruch Z
- Bastianelli D
- Battles J
- Bauerle W
- Bauters M
- Bazzato E
- Beckmann M
- Beeckman H
- Beierkuhnlein C
- Bekker R
- Belfry G
- Belluau M
- Beloiu M
- Benavides R
- Benomar L
- Berdugo-Lattke ML
- Berenguer E
- Bergamin R
- Bergmann J
- Berner L
- Bernhardt-Roemermann M
- Bigler C
- Bjorkman AD
- Blackman C
- Blanco C
- Blonder B
- Blumenthal D
- Bocanegra-Gonzalez KT
- Boeckx P
- Boehning-Gaese K
- Boenisch G
- Bohlman S
- Boisvert-Marsh L
- Bond W
- Bond-Lamberty B
- Boom A
- Boonman CCF
- Bordin K
- Boughton EH
- Boukili V
- Bowman DMJS
- Bravo S
- Brendel MR
- Broadley MR
- Brown KA
- Bruelheide H
- Brumnich F
- Bruun HH
- Bruy D
- Buchanan SW
- Bucher SF
- Buchmann N
- Buerger J
- Buitenwerf R
- Bunker DE
- Burrascano S
- Burslem DFRP
- Butterfield BJ
- Byun C
- Caccianiga M
- Cadotte M
- Cailleret M
- Camac J
- Campany C
- Campetella G
- Campos JA
- Cano-Arboleda L
- Canullo R
- Carbognani M
- Carlos S
- Carlucci MB
- Carolina Santacruz-Garcia A
- Carvalho F
- Casanoves F
- Castagneyrol B
- Catford JA
- Cavender-Bares J
- Cerabolini BEL
- Cervellini M
- Chacon-Madrigal E
- Chapin FS
- Chapin K
- Chelli S
- Chen A
- Chen S-C
- Cherubini P
- Chianucci F
- Choat B
- Chung K-S
- Chytry M
- Ciccarelli D
- Coll L
- Collins CG
- Conti L
- Coomes D
- Cornelissen JHC
- Cornwell WK
- Corona P
- Coyea M
- Craine J
- Craven D
- Cromsigt JPGM
- Csecserits A
- Cufar K
- Cuntz M
- da Silva AC
- Dahlin KM
- Dainese M
- Dalke I
- Dalle Fratte M
- Danihelka J
- Dannoura M
- Dawson S
- de Beer AJ
- De Frutos A
- De Long JR
- Dechant B
- Delagrange S
- Delpierre N
- Derroire G
- Dias AS
- Diaz S
- Diaz-Toribio MH
- Dimitrakopoulos PG
- Dobrowolski M
- Doktor D
- Domingues TF
- Dong N
- Dransfield J
- Dressler S
- Drevojan P
- Duarte L
- Ducouret E
- Dullinger S
- Durka W
- Duursma R
- Dymova O
- E-Vojtko A
- Eckstein RL
- Ejtehadi H
- Elser J
- Emilio T
- Engemann K
- Erfanian MB
- Erfmeier A
- Esquivel-Muelbert A
- Esser G
- Estiarte M
- Fagan WF
- Fagundez J
- Falster DS
- Fan Y
- Fang J
- Farris E
- Fazlioglu F
- Feng Y
- Fernandez-Mendez F
- Ferrara C
- Ferreira J
- Fidelis A
- Finegan B
- Firn J
- Flowers TJ
- Flynn DFB
- Fontana V
- Forey E
- Forgiarini C
- Francois L
- Frangipani M
- Frank D
- Frenette-Dussault C
- Freschet GT
- Fry EL
- Fyllas NM
- Gachet S
- Gallagher R
- Ganade G
- Ganga F
- Garcia-Palacios P
- Gargaglione V
- Garnier E
- Gea-Izquierdo G
- Gibson D
- Gillison AN
- Giroldo A
- Glasenhardt M-C
- Gleason S
- Gliesch M
- Goeldel B
- Goldberg E
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- Gonzalez-Andujar JL
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- Graae BJ
- Granda E
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- Gregor T
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- Guenther A
- Guerin GR
- Gutierrez AG
- Haddock L
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- Hambuckers A
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- Harrison SP
- Hattingh W
- Hawes JE
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- Heberling JM
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- Kloeppel B
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- Knops JMH
- Koenig C
- Kohyama T
- Koike F
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- Komac B
- Komatsu K
- Kraft NJB
- Kramer K
- Kreft H
- Kuehn I
- Kumarathunge D
- Kuppler J
- Kurokawa H
- Kurosawa Y
- Kuyah S
- Laclau J-P
- Lafleur B
- Lallai E
- Lamb E
- Lamprecht A
- Larkin DJ
- Laughlin D
- Laura Suarez M
- Lavorel S
- Le Bagousse-Pinguet Y
- le Maire G
- le Roux E
- le Roux PC
- Leadley P
- Lee T
- Lens F
- Lewis SL
- Lhotsky B
- Li X
- Li Y
- Lichstein JW
- Liebergesell M
- Lim JY
- Lin Y-S
- Linares JC
- Liu C
- Liu D
- Liu U
- Livingstone S
- Llusia J
- Lohbeck M
- Lopez-Garcia A
- Lopez-Gonzalez G
- Lososova Z
- Louault F
- Luis de Gasper A
- Luis Garrido J
- Luis Peri P
- Lukacs BA
- Lukes P
- Luo Y
- Lussu M
- Ma S
- Mack M
- Maire V
- Makela A
- Makinen H
- Mallik A
- Manning P
- Manzoni S
- Marchetti Z
- Marchino L
- Marcilio-Silva V
- Marcon E
- Marignani M
- Markesteijn L
- Marques M
- Martin A
- Martinez-Garza C
- Martinez-Vilalta J
- Maskova T
- Mason K
- Mason N
- Massad TJ
- Masse J
- Mayrose I
- Mazzochini GG
- McCarthy J
- McCormack ML
- McCulloh K
- McFadden IR
- McGill BJ
- McPartland MY
- Medeiros JS
- Medlyn B
- Meerts P
- Mehrabi Z
- Meir P
- Melo FPL
- Mencuccini M
- Mendes Malhado AC
- Meredieu C
- Messier J
- Meszaros I
- Metsaranta J
- Michaletz ST
- Michelaki C
- Migalina S
- Milla R
- Miller JED
- Minden V
- Ming R
- Mokany K
- Moles AT
- Molnar A
- Molofsky J
- Molz M
- Montgomery RA
- Monty A
- Moravcova L
- Moreno-Martinez A
- Moretti M
- Mori AS
- Mori S
- Morris D
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- Mucina L
- Mueller S
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- Myers-Smith IH
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- Rosenfield MF
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- Rueger N
- Ruiz-Peinado R
- Rumpf SB
- Rusch GM
- Ryo M
- Sack L
- Saldana A
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- Santa-Regina I
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- Scalon MC
- Schamp B
- Scherer-Lorenzen M
- Schleuning M
- Schmid B
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- Schneider JV
- Schowanek SD
- Schrader J
- Schrodt F
- Schuldt B
- Schurr F
- Selaya Garvizu G
- Semchenko M
- Seymour C
- Sfair JC
- Sharpe JM
- Sheppard CS
- Sheremetiev S
- Shiodera S
- Shipley B
- Shovon TA
- Siebenkaes A
- Silva M
- Silva V
- Sitzia T
- Sjoman H
- Slot M
- Smith NG
- Sodhi D
- Soltis D
- Soltis P
- Somers B
- Sonnier G
- Sorensen MV
- Sosinski EE
- Soudzilovskaia NA
- Souza AF
- Spasojevic M
- Sperandii MG
- Stan AB
- Stegen J
- Steinbauer K
- Stephan JG
- Sterck F
- Stojanovic DB
- Strydom T
- Svenning J-C
- Svitkova I
- Svitok M
- Svoboda M
- Swaine E
- Swenson N
- Tabarelli M
- Takagi K
- Tappeiner U
- Tarifa R
- Tarin T
- Tautenhahn S
- Tauugourdeau S
- Tavsanoglu C
- te Beest M
- Tedersoo L
- Thiffault N
- Thom D
- Thomas E
- Thompson K
- Thornton PE
- Thuiller W
- Tichy L
- Tissue D
- Tjoelker MG
- Tng DYP
- Tobias J
- Torok P
- Torres-Ruiz JM
- Tothmeresz B
- Treurnicht M
- Trivellone V
- Trolliet F
- Trotsiuk V
- Tsakalos JL
- Tsiripidis I
- Tysklind N
- Umehara T
- Usoltsev V
- Vadeboncoeur M
- Vaezi J
- Valladares F
- Vamosi J
- van Bodegom PM
- van Breugel M
- Van Cleemput E
- van de Weg M
- van der Merwe S
- van der Plas F
- van der Sande MT
- van Kleunen M
- Van Meerbeek K
- Vanderwel M
- Vanselow KA
- Varhammar A
- Varone L
- Vasquez Valderrama MY
- Vassilev K
- Vellend M
- Veneklaas EJ
- Verbeeck H
- Verheyen K
- Vibrans A
- Vieira I
- Villacis J
- Violle C
- Vivek P
- Wagner K
- Waldram M
- Waldron A
- Walker AP
- Waller M
- Walther G
- Wang F
- Wang H
- Wang W
- Watkins H
- Watkins J
- Weber U
- Weedon JT
- Wei L
- Weigelt P
- Weiher E
- Wells AW
- Wellstein C
- Wenk E
- Werner GDA
- Westoby M
- Westwood A
- White PJ
- Whitten M
- Williams M
- Winkler DE
- Winter K
- Wirth C
- Womack C
- Wright IJ
- Wright J
- Wright SJ
- Ximenes F
- Yamada T
- Yamaji K
- Yanai R
- Yankov N
- Yguel B
- Zanini KJ
- Zanne AE
- Zeleny D
- Zhao Y-P
- Zheng J
- Zheng J
- Zieminska K
- Zirbel CR
- Zizka G
- Zo-Bi IC
- Zotz G
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/01/2020
- Field of study
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits—almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
- Author
- Aase Handberg
- Abhijna R Ballal
- Abhimanyu Thakur
- Abuelreich Sarah
- Achille Anselmo
- Adam L Maddox
- Adityas Purnianto
- Adrian E Morelli
- Adrian L Harris
- Adriana F Paes Leme
- Adriana T Larregina
- Afrodité Németh
- Afsareen Bano
- Agnieszka Razim
- Agustin Enciso-Martinez
- Ahmed Ge Ibrahim
- Ahmed Somaida
- Aija Linē
- Ainhoa Alberro
- Ajay P Singh
- Akbar L Marzan
- Akhil Srivastava
- Akira Yokoi
- Al Charest
- Alain R Brisson
- Alan J Zimmerman
- Albano Cáceres-Verschae
- Aled Clayton
- Aleksandra Inic-Kanada
- Aleksei Tikhonov
- Alena Ivanova
- Alessandra Ciullo
- Alessandro Gori
- Alessio Noghero
- Alex J Rai
- Alexander Otahal
- Alexander R Ivanov
- Alexis G Murillo Carrasco
- Alice Gualerzi
- Alicia Galinsoga
- Alicia Llorente
- Aliosha I Figueroa-Valdés
- Alireza Fazeli
- Alissa M Weaver
- Alok Raghav
- Alvaro Compañ-Bertomeu
- Amanda Khoo
- Amanda Salviano-Silva
- Amandine Bonifay
- Amankeldi A Salybekov
- Amélie Nadeau
- Amin Zakeri
- Amirmohammad Nasiri Kenari
- Amit K Srivastava
- Amy A Baxter
- Amy C Kauffman
- Amy H Buck
- An Hendrix
- Ana C Torrecilhas
- Ana I Salazar-Puerta
- Ana O'Loghlen
- Anabela Cordeiro-da-Silva
- Anaïs Bécot
- Anders T Boysen
- Andras G Miklosi
- Andras Saftics
- András I Försönits
- Andre J van Wijnen
- Andrea Galisova
- Andrea Ridolfi
- Andrea Zendrini
- Andreas Möller
- Andreia M Silva
- Andreina Schoeberlein
- Andreu Matamoros-Angles
- Andrew Devitt
- Andrew F Hill
- Andrew Lai
- Andrew Rowland
- André Cronemberger-Andrade
- André Görgens
- Andries Zijlstra
- Angela M Zivkovic
- Angelica Ortiz
- Angelo Musicò
- Ann M Wehman
- Anna Antoniou
- Anna C Berardi
- Anna Cifuentes-Rius
- Anna D Krasnodembskaya
- Anna Koncz
- Anna M Schmid
- Anna Romolo
- Annaïg J Rozo
- Annalisa Radeghieri
- Annie Frelet-Barrand
- Annika Pfeiffer
- Anthony W Ferrante Jr
- Antje M Zickler
- Antoine Karoichan
- Antonella Bongiovanni
- Antonia Hufnagel
- Antonia Reale
- Antonio da Silva Novaes
- Antonio Marcilla
- Apolonija Bedina-Zavec
- Apurba Dev
- Asa M Wheelock
- Ashish Kumar
- Ashley E Russell
- Ashok K Shetty
- Asima Bhattacharyya
- Attila Oláh
- Augusto Zani
- Aurelia Rughetti
- Aurelio Lorico
- Aurélie Ledreux
- Avital A Rodal
- Ayesha Saleem
- Ákos M Lőrincz
- Áurea M Gabriel
- Bagabas Reem
- Baharak Hosseinkhani
- Bahnisikha Barman
- Bairen Pang
- Bas Wm van Balkom
- Batuhan T Bozkurt
- Beate Vestad
- Benedetta Bussolati
- Benjamin Jurek
- Benjamin Mary
- Bergese Paolo
- Berglind E Benediktsdóttir
- Bernadett R Bodnár
- Bernd Giebel
- Bert Dhondt
- Berta Puig
- Beth Coyle
- Beth Holder
- Bianca C Pachane
- Biao Lu
- Bingdong Sui
- Birke J Benedikter
- Blenkiron Cherie
- Bo Li
- Bojana Milutinovic
- Bong Hwan Sung
- Bonita H Powell
- Brachyahu M Kestecher
- Bradley Whitehead
- Brian Dobosh
- Bridges Esther M.
- Brucale Marco
- Bruce A Stanton
- Burger Dylan
- Bussolati Benedetta
- Buzas Edit I.
- Byeong Hyeon Choi
- Cai Houjian
- Camille Ettelaie
- Camille V Trinidad
- Cansu Gorgun
- Carla Mazzeo
- Carlos Salomon
- Carmen Campos-Silva
- Carmen Carceller
- Carmen Fernandez-Becerra
- Carmen Jerónimo
- Carney Randy P.
- Carolina Balbi
- Carolina Soekmadji
- Caroline Gilbert
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- Catherine Martel
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- Celine Elie-Caille
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- Kruh‐Garcia Nicole A.
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- Manuel Varas-Godoy
- Manuela Basso
- Marc-André Langlois
- Marca Hm Wauben
- Marcel I Ramirez
- Marcela A Cucher
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- Maria Noé Garcia
- Mariama Mbengue
- Marianne S Joerger-Messerli
- Marieke T Roefs
- Marija Holcar
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- Marina Cretich
- Mario Gimona
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- Marit Inngjerdingen
- María Fernández-Rhodes
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- Mark C Allenby
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- Marni D Boppart
- Marta Garcia-Contreras
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- Martens‐Uzunova Elena S.
- Martijn Jc van Herwijnen
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- Martin Olivier
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- Marvin Droste
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- Masako Harada
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- Massimo Bottini
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- Saugstad Julie A.
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- Stephanie F Rutter
- Stephanie Jung
- Stephanie M Bollard
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- Steven M Jay
- Stuart Hunt
- Subbaya Subramanian
- Subhadip Ghatak
- Sujan K Mondal
- Sujata Mohanty
- Sukhbir Kaur
- Suman Dutta
- Sun Young Lee
- Suresh Mathivanan
- Surya Shrivastava
- Susann Allelein
- Susanne Gabrielsson
- Susanne Krasemann
- Susmita Sahoo
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- Sveva Bollini
- Swasti Tiwari
- Swift Simon
- Sylwia Bobis-Wozowicz
- Syrine Arif
- Tae Ryong Lee
- Taeyoung Kang
- Takahiro Ochiya
- Takanori Eguchi
- Tamás Beke-Somfai
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- Tania Limongi
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- Ter‐Ovanesyan Dmitry
- Thabiso E Motaung
- Thanh Kha Phan
- Theresa L Whiteside
- Théry Clotilde
- Thibaud Dauphin
- Thomas Kislinger
- Thomas Michael Shiju
- Thupten Tsering
- Tiana F Koukoulis
- Tijana Jovanovic-Talisman
- Timothea Konstantinou
- Timothy V Domashevich
- Tine Hiorth Schøyen
- Tobias Tertel
- Tom Ap Driedonks
- Tom G Keulers
- Tommaso Neri
- Tomofumi Yamamoto
- Tong Wang
- Torrecilhas Ana C.
- Tosar Juan P.
- Trude Aspelin
- Tsuneya Ikezu
- Ursula S Sandau
- Useckaite Zivile
- Uta Erdbrügger
- Valentina R Minciacchi
- Valentina Zappulli
- Valeria Barreca
- Valle Francesco
- van der Pol Edwin
- van Herwijnen Martijn J. C.
- Varga Zoltan
- Vasiliki Mahairaki
- Vasiliy S Chernyshev
- Vatsal Deliwala
- Veer Bala Gupta
- Vendula Pospichalova
- Vengala Rao Yenuganti
- Venkatesh Kumar Chetty
- Vera A Tang
- Vera Mugoni
- Vera Tscherrig
- Verity J Ford
- Verline Justilien
- Veronica Huber
- Veronika Kralj-Iglic
- Veronika Stoka
- Victor Bodart-Santos
- Vijaya Sunkara
- Vikramsingh Gujar
- Viktoria Szeifert
- Viktoria Weber
- Vincent Hyenne
- Vincent Yeung
- Vincenza Dolo
- Violaine Moreau
- Vito G D'Agostino
- Vivek Kumar Gupta
- Vladimir Bokun
- Vroniqa Ku'ulei-Lyn Faustino
- Vytautas Žėkas
- Wai-Leng Lee
- Wanessa F Altei
- Wauben Marca H. M.
- Wehman Ann M.
- Wei Duan
- Wei Guo
- Wei Seong Toh
- Welsh Joshua A.
- Wen-Wei Chang
- Wilfrid Boireau
- Wilfried W Bazié
- Willem Stoorvogel
- Williams Sarah
- Witwer Kenneth W.
- Wolfgang Holnthoner
- Wyatt N Vreeland
- Xabier Osteikoetxea
- Xandra O Breakefield
- Xavier Loyer
- Xiaomei Yan
- Xiaoqin Wang
- Xinhua Lei
- Xinlei Li
- Xiuming Liang
- Yagmur Yildizhan
- Yang You
- Yasuo Inoshima
- Yi Wen
- Yinghong Zhou
- Yingtang Gao
- Yiyao Huang
- Yoel Sadovsky
- Yohan Kim
- Yong Song Gho
- Yongkang Yang
- Yonis Bare
- Yoon-Kyoung Cho
- Yoshinobu Takakura
- Young-Gyun Park
- Yu Fujita
- Yu Xiao
- Yuki Yamamoto
- Yumi Kumagai
- Yunjie Wu
- Yunxi Chen
- Yusuke Yamamoto
- Yusuke Yoshioka
- Yvan Courageux
- Yvonne Couch
- Zach Troyer
- Zendrini Andrea
- Zheng Lei
- Zheng Zhao
- Zijlstra Andries
- Zimmerman Alan J.
- Zivile Useckaite
- Zoltan Varga
- Zoltán Varga
- Zoltán Wiener
- Zucai Suo
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly
Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies
- Author
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- Abe T.
- Abelha P.
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- Zogheib E. H.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background: Geoeconomic variations in epidemiology, the practice of ventilation, and outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data of four large observational studies. Methods: In this pooled analysis we harmonised individual patient data from the ERICC, LUNG SAFE, PRoVENT, and PRoVENT-iMiC prospective observational studies, which were conducted from June, 2011, to December, 2018, in 534 ICUs in 54 countries. We used the 2016 World Bank classification to define two geoeconomic regions: middle-income countries (MICs) and high-income countries (HICs). ARDS was defined according to the Berlin criteria. Descriptive statistics were used to compare patients in MICs versus HICs. The primary outcome was the use of low tidal volume ventilation (LTVV) for the first 3 days of mechanical ventilation. Secondary outcomes were key ventilation parameters (tidal volume size, positive end-expiratory pressure, fraction of inspired oxygen, peak pressure, plateau pressure, driving pressure, and respiratory rate), patient characteristics, the risk for and actual development of acute respiratory distress syndrome after the first day of ventilation, duration of ventilation, ICU length of stay, and ICU mortality. Findings: Of the 7608 patients included in the original studies, this analysis included 3852 patients without ARDS, of whom 2345 were from MICs and 1507 were from HICs. Patients in MICs were younger, shorter and with a slightly lower body-mass index, more often had diabetes and active cancer, but less often chronic obstructive pulmonary disease and heart failure than patients from HICs. Sequential organ failure assessment scores were similar in MICs and HICs. Use of LTVV in MICs and HICs was comparable (42\ub74% vs 44\ub72%; absolute difference \u20131\ub769 [\u20139\ub758 to 6\ub711] p=0\ub767; data available in 3174 [82%] of 3852 patients). The median applied positive end expiratory pressure was lower in MICs than in HICs (5 [IQR 5\u20138] vs 6 [5\u20138] cm H2O; p=0\ub70011). ICU mortality was higher in MICs than in HICs (30\ub75% vs 19\ub79%; p=0\ub70004; adjusted effect 16\ub741% [95% CI 9\ub752\u201323\ub752]; p<0\ub70001) and was inversely associated with gross domestic product (adjusted odds ratio for a US$10 000 increase per capita 0\ub780 [95% CI 0\ub775\u20130\ub786]; p<0\ub70001). Interpretation: Despite similar disease severity and ventilation management, ICU mortality in patients without ARDS is higher in MICs than in HICs, with a strong association with country-level economic status. Funding: No funding
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