547 research outputs found

    Effects of Landscape Design on Urban Microclimate and Thermal Comfort in Tropical Climate

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    A climate-responsive landscape design can create a more livable urban microclimate with adequate human comfortability. This paper aims to quantitatively investigate the effects of landscape design elements of pavement materials, greenery, and water bodies on urban microclimate and thermal comfort in a high-rise residential area in the tropic climate of Singapore. A comprehensive field measurement is undertaken to obtain real data on microclimate parameters for calibration of the microclimate-modeling software ENVI-met 4.0. With the calibrated ENVI-met, seven urban landscape scenarios are simulated and their effects on thermal comfort as measured by physiologically equivalent temperature (PET) are evaluated. It is found that the maximum improvement of PET reduction with suggested landscape designs is about 12°C, and high-albedo pavement materials and water bodies are not effective in reducing heat stress in hot and humid climate conditions. The combination of shade trees over grass is the most effective landscape strategy for cooling the microclimate. The findings from the paper can equip urban designers with knowledge and techniques to mitigate urban heat stress

    Design optimization considering variable thermal mass, insulation, absorptance of solar radiation, and glazing ratio using a prediction model and genetic algorithm

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    This paper presents the optimization of building envelope design to minimize thermal load and improve thermal comfort for a two-star green building in Wuhan, China. The thermal load of the building before optimization is 36% lower than a typical energy-efficient building of the same size. A total of 19 continuous design variables, including different concrete thicknesses, insulation thicknesses, absorbance of solar radiation for each exterior wall/roof and different window-to-wall ratios for each façade, are considered for optimization. The thermal load and annual discomfort degree hours are selected as the objective functions for optimization. Two prediction models, multi-linear regression (MLR) model and an artificial neural network (ANN) model, are developed to predict the building thermal performance and adopted as fitness functions for a multi-objective genetic algorithm (GA) to find the optimal design solutions. As compared to the original design, the optimal design generated by the MLRGA approach helps to reduce the thermal load and discomfort level by 18.2% and 22.4%, while the reductions are 17.0% and 22.2% respectively, using the ANNGA approach. Finally, four objective functions using cooling load, heating load, summer discomfort degree hours, and winter discomfort degree hours for optimization are conducted, but the results are no better than the two-objective-function optimization approach

    A Review of Recent Advances in Research on PM2.5 in China

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    PM2.5 pollution has become a severe problem in China due to rapid industrialization and high energy consumption. It can cause increases in the incidence of various respiratory diseases and resident mortality rates, as well as increase in the energy consumption in heating, ventilation, and air conditioning (HVAC) systems due to the need for air purification. This paper reviews and studies the sources of indoor and outdoor PM2.5, the impact of PM2.5 pollution on atmospheric visibility, occupational health, and occupants’ behaviors. This paper also presents current pollution status in China, the relationship between indoor and outdoor PM2.5, and control of indoor PM2.5, and finally presents analysis and suggestions for future research

    Development of Building Thermal Load and Discomfort Degree Hour Prediction Models Using Data Mining Approaches

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    Thermal load and indoor comfort level are two important building performance indicators, rapid predictions of which can help significantly reduce the computation time during design optimization. In this paper, a three-step approach is used to develop and evaluate prediction models. Firstly, the Latin Hypercube Sampling Method (LHSM) is used to generate a representative 19-dimensional design database and DesignBuilder is then used to obtain the thermal load and discomfort degree hours through simulation. Secondly, samples from the database are used to develop and validate seven prediction models, using data mining approaches including multilinear regression (MLR), chi-square automatic interaction detector (CHAID), exhaustive CHAID (ECHAID), back-propagation neural network (BPNN), radial basis function network (RBFN), classification and regression trees (CART), and support vector machines (SVM). It is found that the MLR and BPNN models outperform the others in the prediction of thermal load with average absolute error of less than 1.19%, and the BPNN model is the best at predicting discomfort degree hour with 0.62% average absolute error. Finally, two hybrid models—MLR (MLR + BPNN) and MLR-BPNN—are developed. The MLR-BPNN models are found to be the best prediction models, with average absolute error of 0.82% in thermal load and 0.59% in discomfort degree hour

    Efeito de jogos lúdico-recreativos de cooperação-oposição no nível da atividade física e nas interações em ciranças no 1º ciclo do ensino básico

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    No presente estudo, a amostra foi constituída por 10 crianças, 5 rapazes (n=5; 5,8 ± 0,4 anos de idade) e 5 raparigas (n=5; 5,6 ± 0,5 anos de idade), de uma escola do 1.ºCiclo do Ensino Básico. O objetivo do presente trabalho passa por quantificar as interações – através do Social Network Analysis - e o nível de atividade física das crianças – através de acelerómetros - durante diferentes jogos lúdico-recreativos de cooperação-oposição. Os resultados sugerem que, na atividade física, o “Posse de Bola” foi o jogo em que as crianças realizaram um maior número de passos, enquanto no “Jogo do Meinho” e no “Jogo Livre” as crianças passaram mais tempo em atividade vigorosa. Ao nível das métricas de Social Network Analysis: no jogo “Posse de Bola” grupo de 5 foi onde as crianças interagiram com os pares, sem necessitarem de muitos intermediários (CC); grupo de 5 do “Golo Fácil” e “Posse de Bola”, foram os jogos onde as crianças foram fundamentais para manter as intermediações das interações entre os passes (BC); no jogo “Jogo Livre” grupo de 5 foi onde as crianças tiveram tendência para interagir com uma criança em específico (PP); o “Jogo do Meinho” no grupo de 5 foi onde as crianças interagiram mais com uns colegas do que com outros (CLC); os grupos de 5 foi onde as crianças interagiram entre si, tendo colegas em comum nas suas interações (TO); a maioria dos grupos de 5, em todos os jogos, foi onde as crianças interagiram com as crianças que se apresentavam similares nas interação (AC); os grupos de 5 do “Jogo do Meinho”, “Golo Fácil” e “Posse de Bola”, foi onde se verificou um melhor nível de interações entre as crianças, existindo uma maior homogeneidade (ND); os grupos de 10 do “Jogo do Meinho” e “Golo Fácil”, foram os jogos onde as crianças tiveram tendência para interagir com os mesmos pares (T); os grupos de 5 e 10 foi onde as crianças tiveram tendência para interagir com quem interagiu com elas (R) e, por fim, os grupos de 5, foi onde mais crianças interagiram de uma forma direta entre si (GP)

    Rare B Decays with a HyperCP Particle of Spin One

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    In light of recent experimental information from the CLEO, BaBar, KTeV, and Belle collaborations, we investigate some consequences of the possibility that a light spin-one particle is responsible for the three Sigma^+ -> p mu^+ mu^- events observed by the HyperCP experiment. In particular, allowing the new particle to have both vector and axial-vector couplings to ordinary fermions, we systematically study its contributions to various processes involving b-flavored mesons, including B-Bbar mixing as well as leptonic, inclusive, and exclusive B decays. Using the latest experimental data, we extract bounds on its couplings and subsequently estimate upper limits for the branching ratios of a number of B decays with the new particle. This can serve to guide experimental searches for the particle in order to help confirm or refute its existence.Comment: 17 pages, 3 figures; discussion on spin-0 case modified, few errors corrected, main conclusions unchange

    Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70

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    Various subsets of invariant natural killer T (iNKT) cells with different cytokine productions develop in the mouse thymus, but the factors driving their differentiation remain unclear. Here we show that hypomorphic alleles of Zap70 or chemical inhibition of Zap70 catalysis leads to an increase of IFN-gamma-producing iNKT cells (NKT1 cells), suggesting that NKT1 cells may require a lower TCR signal threshold. Zap70 mutant mice develop IL-17-dependent arthritis. In a mouse experimental arthritis model, NKT17 cells are increased as the disease progresses, while NKT1 numbers negatively correlates with disease severity, with this protective effect of NKT1 linked to their IFN-gamma expression. NKT1 cells are also present in the synovial fluid of arthritis patients. Our data therefore suggest that TCR signal strength during thymic differentiation may influence not only IFN-gamma production, but also the protective function of iNKT cells in arthritis

    Learning Transcriptional Regulatory Relationships Using Sparse Graphical Models

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    Understanding the organization and function of transcriptional regulatory networks by analyzing high-throughput gene expression profiles is a key problem in computational biology. The challenges in this work are 1) the lack of complete knowledge of the regulatory relationship between the regulators and the associated genes, 2) the potential for spurious associations due to confounding factors, and 3) the number of parameters to learn is usually larger than the number of available microarray experiments. We present a sparse (L1 regularized) graphical model to address these challenges. Our model incorporates known transcription factors and introduces hidden variables to represent possible unknown transcription and confounding factors. The expression level of a gene is modeled as a linear combination of the expression levels of known transcription factors and hidden factors. Using gene expression data covering 39,296 oligonucleotide probes from 1109 human liver samples, we demonstrate that our model better predicts out-of-sample data than a model with no hidden variables. We also show that some of the gene sets associated with hidden variables are strongly correlated with Gene Ontology categories. The software including source code is available at http://grnl1.codeplex.com
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