434 research outputs found

    Pulmonary stretch receptor activity during partial liquid ventilation in cats with healthy lungs

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    Aim: To study whether pulmonary stretch receptor (PSR) activity in mechanically ventilated young cats with healthy lungs during partial liquid ventilation (PLV) is different from that during gas ventilation (GV). Methods: In 10 young cats (4.4 +/- 0.4 months, 2.3 +/- 0.3 kg; mean B SD), PSR instantaneous impulse frequency (PSR f(imp)) was recorded from single fibres in the vagal nerve during GV and PLV with perfluorocarbon (30 ml/kg) at increasing positive inspiratory pressures (PIP; 1.2, 1.8, 2.2 and 2.7 kPa), and at a positive end-expiratory pressure of 0.5 kPa. Results: All PSRs studied during GV maintained their phasic character with increased impulse frequency during inspiration during PLV. Peak PSR fimp was lower at PIP 1.2 kPa (p < 0.05) and at PIP 2.7 kPa (p = 0.10) during PLV than during GV, giving a lower number of PSR impulses at these two settings during PLV (p < 0.05). Conclusion: The phasic character of PSR activity is similar during GV and PLV. PSR activity is not higher during PLV than during GV in cats with healthy lungs, indicating no extensive stretching of the lung during PLV. Copyright (C) 2004 S. Karger AG, Basel

    Inference of hidden structures in complex physical systems by multi-scale clustering

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    We survey the application of a relatively new branch of statistical physics--"community detection"-- to data mining. In particular, we focus on the diagnosis of materials and automated image segmentation. Community detection describes the quest of partitioning a complex system involving many elements into optimally decoupled subsets or communities of such elements. We review a multiresolution variant which is used to ascertain structures at different spatial and temporal scales. Significant patterns are obtained by examining the correlations between different independent solvers. Similar to other combinatorial optimization problems in the NP complexity class, community detection exhibits several phases. Typically, illuminating orders are revealed by choosing parameters that lead to extremal information theory correlations.Comment: 25 pages, 16 Figures; a review of earlier work

    Acoustic cloak based on Bézier scatterers

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    [EN] Among the different approaches proposed to design acoustic cloaks, the one consisting on the use of an optimum distribution of discrete scatters surrounding the concealing object has been successfully tested. The feasibility of acoustic cloaks mainly depends on the number and shape of the scatterers surrounding the object to be cloaked. This work presents a method allowing the reduction of the number of discrete scatterers by optimizing their external shape, which is here defined by a combination of cubic Bézier curves. Based on scattering cancellation, a two-dimensional directional cloak consisting of just 20 Bézier scatters has been designed, fabricated and experimentally characterized. The method of fundamental solutions has been implemented to calculate the interaction of an incident plane wave with scatterers of arbitrary shape. The acoustic cloak here proposed shows a performance, in terms of averaged visibility, similar to that consisting of 120 scatterers with equal circular cross sections. The operational frequency of the proposed cloak is 5940 Hz with a bandwidth of about 110 Hz.J. Sanchez-Dehesa acknowledges the financial support by the Spanish Ministerio de Economia y Competitividad and the European Union Fondo Europeo para el Desarrollo Regional (FEDER) under Grant with Ref. TEC2014-53088-C3-1-R. Lu Zhimiao acknowledges the financial support from the program of China Scholarships Council (No. 201503170282), Wen Jihong, Cai Li and Lu Zhimiao acknowledge the support by National Natural Science Foundation of China (Grant Nos 51275519 and 11372346)Lu, Z.; Sanchis Martínez, L.; Wen, J.; Cai, L.; Bi, Y.; Sánchez-Dehesa Moreno-Cid, J. (2018). Acoustic cloak based on Bézier scatterers. Scientific Reports. 8. https://doi.org/10.1038/s41598-018-30888-7S8Cummer, S. A. & Schurig, D. One path to acoustic cloaking. New J. Phys. 9(3), 45 (2007).Cai, L.-W. & Sánchez-Dehesa Analysis of Cummer–Schurig acoustic cloaking. J. New J. Phys. 9(12), 450 (2007).Chen, H. & Chan, C. Acoustic cloaking in three dimensions using acoustic metamaterials. Appl. Phys. Lett. 91(18), 183518 (2007).Norris, A. N. Acoustic cloaking theory. Proc. R. Soc. A 464(2097), 2411–2434 (2008).Torrent, D. & Sánchez-Dehesa, J. Acoustic cloaking in two dimensions: a feasible approach. New J. Phys. 10(6), 063015 (2008).Zhang, S., Xia, C. & Fang, N. Broadband acoustic cloak for ultrasound waves. Phys. Rev. Lett. 106, 024301 Jan (2011).Popa, B.-I., Zigoneanu, L. & Cummer, S. A. Experimental acoustic ground cloak in air. Phys. Rev. Lett. 106, 253901 Jun (2011).Zigoneanu, L., Popa, B.-I. & Cummer, S. A. Design and measurements of a broadband two-dimensional acoustic lens. Nat. Mat 13, 352 (2014).Kan, W. et al. Broadband acoustic cloaking within an arbitrary hard cavity. Phys. Rev. Applied 3, 064019 Jun (2015).Scandrett, C. L., Boisvert, J. E. & Howarth, T. R. Acoustic cloaking using layered pentamode materials. J. Acoust. Soc. Am. 127(5), 2856–2864 (2010).Chen, Y. et al. Broadband solid cloak for underwater acoustics. Phys. Rev. B 95, 180104 May (2017).Alù, A. & Engheta, N. Achieving transparency with plasmonic and metamaterial coatings. Phys. Rev. E 72(1), 016623 (2005).Guild, M. D., Alu, A. & Haberman, M. R. Cancellation of acoustic scattering from an elastic sphere. J. Acoust. Soc. Am. 129(3), 1355–1365 (2011).García-Chocano, V. M. et al. Acoustic cloak for airborne sound by inverse design. Appl. Phys. Lett. 99(7), 074102 (2011).Sanchis, L. et al. Three-Dimensional Axisymmetric Cloak Based on the Cancellation of Acoustic Scattering from a Sphere. Phys. Rev. Lett. 110, 124301 Mar (2013).Andkjær, J. & Sigmund, O. Topology optimized for Airborne sound. ASME J. Vib. Acoust. 135(2), 041011 (2013).Guild, M. D. Acoustic Cloaking of Spherical Objects Unsing Thin Elastic Coatings. Univ. of Texas at Austin (2012).Guild, M. D., Haberman, M. R. & Alú, A. Plasmonic-type Acoustic cloak made of a bilaminate shell. Phys. Rev. B 86(10), 104302 (2012).Rohde, C. A. et al. Experimental demonstration of underwater acoustic scattering cancellation. Sci. Rep. 5, 13175 (2015).Popa, B.-I. & Cummer, S. A. Cloaking with optimized homogeneous anisotropic layers. Phys. Rev. A 79, 023806 Feb (2009).Urzhumov, Y., Landy, N., Driscoll, T., Basov, D. & Smith, D. R. Thin low-loss dielectric coatings for freespace cloaking. Opt. Lett. 38(10), 1606–1608 (2013).Andkjaer, J. & Sigmund, O. Topology optimized low-contrast all-dielectric optical cloak. Appl. Phys. Lett. 98(2), 021112 (2011).Climente, A., Torrent, D. & Sánchez-Dehesa, J. Sound focusing by gradient index sonic lenses. Applied Physics Letters 97(10), 104103 (2010).Håkansson, A., Sánchez-Dehesa, J. & Sanchis, L. Acoustic lens design by genetic algorithms Phys. Rev. B 70, 214302 Dec (2004).Håkansson, A., Cervera, F. & Sánchez-Dehesa, J. Sound focusing by flat acoustic lenses without negative refraction. Applied Physics Letters 86(5), 054102 (2005).Li, D., Zigoneanu, L., Popa, B.-I. & Cummer, S. A. Design of an acoustic metamaterial lens using genetic algorithms. The Journal of the Acoustical Society of America 132(4), 2823–2833 (2012).Prautzsch, H., Wolfgang Boehm, W. & Paluszny, M. Bézier and B-Spline Techniques. Springer Science & Business Media (2002).Andersen, P. R., Cutanda-Henríquez, V., Aage, N. & Sánchez-Dehesa, J. Viscothermal effects on an acoustic cloak based on scattering cancellation. Proceedings of the 6th International Conference on Noise and Vibration Emerging methods (NOVEM 2018 ), 171971, June (2018).Golberg, D. Genetic Algorithms in Search, Optimization and Learning. Addison Wesley, Reading, MA (1989).Kirkpatrick, S., Gelatt, C. D. & Vecchi, M. P. Optimization by simulated annealing. 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    Dystocia in Friesian cows and its effects on postpartum reproductive performance and milk production

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    A total of 1,243 records for 585 dairy Friesian cows from 1997–2004 were used to study the factors affecting dystocia and its effects on reproductive performance and milk production. The overall incidence of dystocia was 6.9%. The percentage of dystocia decreased with increasing live body weight, age, and parity of cows (P < 0.05); however, it increased with increasing birth weight of calves (P < 0.05). The highest percentage of dystocia was detected in winter season, but the least percentage was in summer season (P < 0.05). The percentage of incidence of dystocia was significantly (P < 0.05) higher with winter feeding compared to summer ration (8.2% vs. 5.1%). The percentage of incidence of dystocia was significantly (P < 0.05) higher with twinning than single calving (15.5% vs. 6.5%), while not significantly affected by the sex of born calves. Incidence of dystocia had adverse effects on reproductive performance and milk yield. The service interval, service period, days open, and calving interval were significantly (P < 0.05) longer in cows afflicted with dystocia compared to normal cows. The conception rate was lower (P < 0.05), but the number of service per conception was higher (P < 0.05) in cows afflicted with dystocia compared to normal cows (60.5% vs. 73.0% and 3.4 vs. 2.7, respectively). Average daily milk yield was lower (P < 0.05) by 1 kg for cows with incidence of dystocia compared to normal cows

    Eu-Social Science: The Role of Internet Social Networks in the Collection of Bee Biodiversity Data

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    Background Monitoring change in species diversity, community composition and phenology is vital to assess the impacts of anthropogenic activity and natural change. However, monitoring by trained scientists is time consuming and expensive. Methodology/Principal Findings Using social networks, we assess whether it is possible to obtain accurate data on bee distribution across the UK from photographic records submitted by untrained members of the public, and if these data are in sufficient quantity for ecological studies. We used Flickr and Facebook as social networks and Flickr for the storage of photographs and associated data on date, time and location linked to them. Within six weeks, the number of pictures uploaded to the Flickr BeeID group exceeded 200. Geographic coverage was excellent; the distribution of photographs covered most of the British Isles, from the south coast of England to the Highlands of Scotland. However, only 59% of photographs were properly uploaded according to instructions, with vital information such as ‘tags’ or location information missing from the remainder. Nevertheless, this incorporation of information on location of photographs was much higher than general usage on Flickr (∼13%), indicating the need for dedicated projects to collect spatial ecological data. Furthermore, we found identification of bees is not possible from all photographs, especially those excluding lower abdomen detail. This suggests that giving details regarding specific anatomical features to include on photographs would be useful to maximise success. Conclusions/Significance The study demonstrates the power of social network sites to generate public interest in a project and details the advantages of using a group within an existing popular social network site over a traditional (specifically-designed) web-based or paper-based submission process. Some advantages include the ability to network with other individuals or groups with similar interests, and thus increasing the size of the dataset and participation in the project

    Matched Filters, Mate Choice and the Evolution of Sexually Selected Traits

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    Background Fundamental for understanding the evolution of communication systems is both the variation in a signal and how this affects the behavior of receivers, as well as variation in preference functions of receivers, and how this affects the variability of the signal. However, individual differences in female preference functions and their proximate causation have rarely been studied. Methodology/Principal Findings Calling songs of male field crickets represent secondary sexual characters and are subject to sexual selection by female choice. Following predictions from the “matched filter hypothesis” we studied the tuning of an identified interneuron in a field cricket, known for its function in phonotaxis, and correlated this with the preference of the same females in two-choice trials. Females vary in their neuronal frequency tuning, which strongly predicts the preference in a choice situation between two songs differing in carrier frequency. A second “matched filter” exists in directional hearing, where reliable cues for sound localization occur only in a narrow frequency range. There is a strong correlation between the directional tuning and the behavioural preference in no-choice tests. This second “matched filter” also varies widely in females, and surprisingly, differs on average by 400 Hz from the neuronal frequency tuning. Conclusions/Significance Our findings on the mismatch of the two “matched filters” would suggest that the difference in these two filters appears to be caused by their evolutionary history, and the different trade-offs which exist between sound emission, transmission and detection, as well as directional hearing under specific ecological settings. The mismatched filter situation may ultimately explain the maintenance of considerable variation in the carrier frequency of the male signal despite stabilizing selection

    Habitat Association and Seasonality in a Mosaic and Bimodal Hybrid Zone between Chorthippus brunneus and C. jacobsi (Orthoptera: Acrididae)

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    Understanding why some hybrid zones are bimodal and others unimodal can aid in identifying barriers to gene exchange following secondary contact. The hybrid zone between the grasshoppers Chorthippus brunneus and C. jacobsi contains a mix of allopatric parental populations and inter-mingled bimodal and unimodal sympatric populations, and provides an ideal system to examine the roles of local selection and gene flow between populations in maintaining bimodality. However, it is first necessary to confirm, over a larger spatial scale, previously identified associations between population composition and season and habitat. Here we use cline-fitting of one morphological and one song trait along two valley transects, and intervening mountains, to confirm previously identified habitat associations (mountain versus valley) and seasonal changes in population composition. As expected from previous findings of studies on a smaller spatial scale, C. jacobsi dominated mountain habitats and mixed populations dominated valleys, and C. brunneus became more prevalent in August. Controlling for habitat and incorporating into the analysis seasonal changes in cline parameters and the standard errors of parental trait values revealed wider clines than previous studies (best estimates of 6.4 to 24.5 km in our study versus 2.8 to 4.7 km in previous studies) and increased percentage of trait variance explained (52.7% and 61.5% for transects 1 and 2 respectively, versus 17.6%). Revealing such strong and consistent patterns within a complex hybrid zone will allow more focused examination of the causes of variation in bimodality in mixed populations, in particular the roles of local selection versus habitat heterogeneity and gene flow between differentiated populations

    Association of food security status with overweight and dietary intake: exploration of White British and Pakistani-origin families in the Born in Bradford cohort.

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    BACKGROUND: Food insecurity has been associated with dietary intake and weight status in UK adults and children although results have been mixed and ethnicity has not been explored. We aimed to compare prevalence and trajectories of weight and dietary intakes among food secure and insecure White British and Pakistani-origin families. METHODS: At 12 months postpartum, mothers in the Born in Bradford cohort completed a questionnaire on food security status and a food frequency questionnaire (FFQ) assessing their child's intake in the previous month; at 18 months postpartum, mothers completed a short-form FFQ assessing dietary intake in the previous 12 months. Weights and heights of mothers and infants were assessed at 12-, 24-, and 36-months postpartum, with an additional measurement of children taken at 4-5 years. Associations between food security status and dietary intakes were assessed using Wilcoxon-Mann-Whitney for continuous variables and χ2 or Fisher's exact tests for categorical variables. Quantile and logistic regression were used to determine dietary intakes adjusting for mother's age. Linear mixed effects models were used to assess longitudinal changes in body mass index (BMI) in mothers and BMI z-scores in children. RESULTS: At 12 months postpartum, White British mothers reported more food insecurity than Pakistani-origin mothers (11% vs 7%; p < 0.01) and more food insecure mothers were overweight. Between 12 and 36 months postpartum, BMI increased more among food insecure Pakistani-origin mothers (β = 0.77 units, [95% Confidence Interval [CI]: 0.40, 1.10]) than food secure (β = 0.44 units, 95% CI: 0.33, 0.55). This was also found in Pakistani-origin children (BMI z-score: food insecure β = 0.40 units, 95% CI: 0.22, 0.59; food secure β = 0.25 units, 95% CI: 0.20, 0.29). No significant increases in BMI were observed for food secure or insecure White British mothers while BMI z-score increased by 0.17 (95% CI: 0.13, 0.21) for food secure White British children. Food insecure mothers and children had dietary intakes of poorer quality, with fewer vegetables and higher consumption of sugar-sweetened drinks. CONCLUSIONS: Food security status is associated with body weight and dietary intakes differentially by ethnicity. These are important considerations for developing targeted interventions
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