THE SOLIDS FLOW IN THE RISER OF A CFB VIEWED BY POSITRON EMISSION PARTICLE TRACKING (PEPT)

The PEPT study of the riser of a CFB determines (i) the acceleration length and time, (ii) the upwards and downwards velocities; (ii) the population densities; (iii) the flow pattern at the riser bottom; and (iv) the existence of different flow regimes for associated operating conditions of gas flow rate (U) and solids circulation flux (G)

THE TRANSPORT DISENGAGEMENT HEIGHT (TDH) IN A BUBBLING FLUIDIZED BED (BFB)

Bubbles bursting at the surface of a BFB project particles into the freeboard. Coarser particles fall back, the solids loading declines with height in the freeboard, and fines are ultimately carried over. The height of declining solids loading is the TDH, measured in this research by Positron Emission Particle Tracking, and modeled from a balance of forces on ejected particles. Model predictions and PEPT-data are in good agreement. Empirical equations overestimate the TDH

Bringing Order to Special Cases of Klee's Measure Problem

Klee's Measure Problem (KMP) asks for the volume of the union of n axis-aligned boxes in d-space. Omitting logarithmic factors, the best algorithm has runtime O*(n^{d/2}) [Overmars,Yap'91]. There are faster algorithms known for several special cases: Cube-KMP (where all boxes are cubes), Unitcube-KMP (where all boxes are cubes of equal side length), Hypervolume (where all boxes share a vertex), and k-Grounded (where the projection onto the first k dimensions is a Hypervolume instance). In this paper we bring some order to these special cases by providing reductions among them. In addition to the trivial inclusions, we establish Hypervolume as the easiest of these special cases, and show that the runtimes of Unitcube-KMP and Cube-KMP are polynomially related. More importantly, we show that any algorithm for one of the special cases with runtime T(n,d) implies an algorithm for the general case with runtime T(n,2d), yielding the first non-trivial relation between KMP and its special cases. This allows to transfer W[1]-hardness of KMP to all special cases, proving that no n^{o(d)} algorithm exists for any of the special cases under reasonable complexity theoretic assumptions. Furthermore, assuming that there is no improved algorithm for the general case of KMP (no algorithm with runtime O(n^{d/2 - eps})) this reduction shows that there is no algorithm with runtime O(n^{floor(d/2)/2 - eps}) for any of the special cases. Under the same assumption we show a tight lower bound for a recent algorithm for 2-Grounded [Yildiz,Suri'12].Comment: 17 page

Can Changes in Eye Movement Scanning Alter the Age-Related Deficit in Recognition Memory?

Older adults typically exhibit poorer face recognition compared to younger adults. These recognition differences may be due to underlying age-related changes in eye movement scanning. We examined whether older adults’ recognition could be improved by yoking their eye movements to those of younger adults. Participants studied younger and older faces, under free viewing conditions (bases), through a gaze-contingent moving window (own), or a moving window which replayed the eye movements of a base participant (yoked). During the recognition test, participants freely viewed the faces with no viewing restrictions. Own-age recognition biases were observed for older adults in all viewing conditions, suggesting that this effect occurs independently of scanning. Participants in the bases condition had the highest recognition accuracy, and participants in the yoked condition were more accurate than participants in the own condition. Among yoked participants, recognition did not depend on age of the base participant. These results suggest that successful encoding for all participants requires the bottom-up contribution of peripheral information, regardless of the locus of control of the viewer. Although altering the pattern of eye movements did not increase recognition, the amount of sampling of the face during encoding predicted subsequent recognition accuracy for all participants. Increased sampling may confer some advantages for subsequent recognition, particularly for people who have declining memory abilities

Identification of a novel distal regulatory element of the human Neuroglobin gene by the chromosome conformation capture approach

Neuroglobin (NGB) is predominantly expressed in the brain and retina. Studies suggest that NGB exerts protective effects to neuronal cells and is implicated in reducing the severity of stroke and Alzheimer's disease. However, little is known about the mechanisms which regulate the cell type-specific expression of the gene. In this study, we hypothesized that distal regulatory elements (DREs) are involved in optimal expression of the NGB gene. By chromosome conformation capture we identified two novel DREs located -70 kb upstream and +100 kb downstream from the NGB gene. ENCODE database showed the presence of DNaseI hypersensitive and transcription factors binding sites in these regions. Further analyses using luciferase reporters and chromatin immunoprecipitation suggested that the -70 kb region upstream of the NGB gene contained a neuronalspecific enhancer and GATA transcription factor binding sites. Knockdown of GATA-2 caused NGB expression to drop dramatically, indicating GATA-2 as an essential transcription factor for the activation of NGB expression. The crucial role of the DRE in NGB expression activation was further confirmed by the drop in NGB level after CRISPR-mediated deletion of the DRE. Taken together, we show that the NGB gene is regulated by a cell type-specific loop formed between its promoter and the novel DRE

Effect of nano and micro-silica on bond behaviour of steel and polypropylene fibres in high volume fly ash mortar

This paper presents the effects of nano silica (NS), micro silica (MS) and combined NS and MS on bond behaviour of steel and polypropylene (PP) fibres in high volume fly ash (HVFA) mortar. Three types of bend configuration of hook-end steel fibre commercially available are considered, while the PP fibre was crimped shape. Three different fly ash contents of 40%, 50% and 60% (by wt) as partial replacement of ordinary Portland cement (OPC) are considered in HVFA mortar, while a control mortar containing 100% OPC was also considered. The NS and the MS was added as 2% and 10% (by wt), respectively as partial replacement of OPC in HVFA mortar containing 40% fly ash. In the case of combined NS and MS, 2% NS and 10% MS was used as partial replacement of OPC in HVFA mortar. However, in the case of HVFA mortars containing 40% fly ash and different NS and MS, total OPC content of 60% was kept constant in all HVFA mixes containing NS, MS and NS + MS. This was considered to compare these mixes with HVFA mortar containing 40% fly ash. Results indicate that maximum pull-out force of both steel and PP fibres decreases with increase in fly ash contents in HVFA mortars at both 7 and 28 days.The addition of 2% NS and 10% MS showed almost similar improvement in the maximum pull-out force of steel and PP fibres at both ages in HVFA mortar containing 40% fly ash. The combined use of 2%NS + 10%MS also improved the maximum pull-out force and higher than 2% NS and 10% MS. The reduction in large capillary pores in HVFA mortars containing nano and micro silica observed in Mercury Intrusion Porosity test improved the bond of steel and PP fibres in those mortar due to formation of additional calcium silicate hydrate (C-S-H) gel is believed to be the reason behind this improvement. The maximum pull-out force also increased with increase in number of bends in the hook-end of steel fibre in all mortars in this study at both 7 and 28 days. Extra energy absorbed by the higher number of bends is the reason of such improvement in maximum pull-out force. However, in the case of absorbed energy mixed results are observed in the case of different number of bends in steel fibre ends. Good correlations also exist between the maximum pull-out forces of all three types of steel fibres with compressive strength of mortars showing strong influence on the bond behaviour

Does anticholinergics drug burden relate to global neuro-disability outcome measures and length of hospital stay?

Primary objective: To assess the relationship between disability, length of stay (LOS) and anticholinergic burden (ACB) with people following acquired brain or spinal cord injury. Research design: A retrospective case note review assessed total rehabilitation unit admission. Methods and procedures: Assessment of 52 consecutive patients with acquired brain/spinal injury and neuropathy in an in-patient neuro-rehabilitation unit of a UK university hospital. Data analysed included: Northwick Park Dependency Score (NPDS), Rehabilitation complexity Scale (RCS), Functional Independence Measure and Functional Assessment Measure FIM-FAM (UK version 2.2), LOS and ACB. Outcome was different in RCS, NPDS and FIM-FAM between admission and discharge. Main outcomes and results: A positive change was reported in ACB results in a positive change in NPDS, with no significant effect on FIM-FAM, either Motor or Cognitive, or on the RCS. Change in ACB correlated to the length of hospital stay (regression correlation = −6.64; SE = 3.89). There was a significant harmful impact of increase in ACB score during hospital stay, from low to high ACB on NPDS (OR = 9.65; 95% CI = 1.36–68.64) and FIM-FAM Total scores (OR = 0.03; 95% CI = 0.002–0.35). Conclusions: There was a statistically significant correlation of ACB and neuro-disability measures and LOS amongst this patient cohort

Type IIB Solutions with Interpolating Supersymmetries

We study type IIB supergravity solutions with four supersymmetries that interpolate between two types widely considered in the literature: the dual of Becker and Becker's compactifications of M-theory to 3 dimensions and the dual of Strominger's torsion compactifications of heterotic theory to 4 dimensions. We find that for all intermediate solutions the internal manifold is not Calabi-Yau, but has SU(3) holonomy in a connection with a torsion given by the 3-form flux. All 3-form and 5-form fluxes, as well as the dilaton, depend on one function appearing in the supersymmetry spinor, which satisfies a nonlinear differential equation. We check that the fields corresponding to a flat bound state of D3/D5-branes lie in our class of solutions. The relations among supergravity fields that we derive should be useful in studying new gravity duals of gauge theories, as well as possibly compactifications.Comment: 27pp, v2 REVTeX4, typographical fixes and minor clarifications, v3 added ref, modified discussion of RR axion slightl

The Fall of Stringy de Sitter

Kachru, Kallosh, Linde, & Trivedi recently constructed a four-dimensional de Sitter compactification of IIB string theory, which they showed to be metastable in agreement with general arguments about de Sitter spacetimes in quantum gravity. In this paper, we describe how discrete flux choices lead to a closely-spaced set of vacua and explore various decay channels. We find that in many situations NS5-brane meditated decays which exchange NSNS 3-form flux for D3-branes are comparatively very fast.Comment: 35 pp (11 pp appendices), 5 figures, v3. fixed minor typo