Data acquisition system for NASA LaRC impact dynamics research facility

A data system is designed to permit the simultaneous recording of 90 data channels on one 28 track magnetic tape recorder using a constant bandwidth FM multiplexing technique. Dynamic signals from transducers located in the test aircraft are amplified and fed to voltage controlled oscillators where they are converted to discrete FM signals. The signals from each group of five VCO's are fed to a mixer/distribution amplifier where they are combined into one composite signal and recorded, using direct recording techniques, on one magnetic tape recorder track. Millivolt signals from the recorders reproduce heads are amplified to one volt and then electronically switched to an FM demultiplexing system where appropriate frequency discrimination and signal filtering recover the original analog information

Theory Summary and Future Directions

Summary talk at the Lepton-Photon Symposium, Cornell University, Aug. 10-15, 1993.Comment: (Talk presented at the Lepton-Photon Symposium, Cornell University, Aug. 10-15, 1993.) 19 page

SB9: The Ninth Catalogue of Spectroscopic Binary Orbits

The Ninth Catalogue of Spectroscopic Binary Orbits (http://sb9.astro.ulb.ac.be) continues the series of compilations of spectroscopic orbits carried out over the past 35 years by Batten and collaborators. As of 2004 May 1st, the new Catalogue holds orbits for 2,386 systems. Some essential differences between this catalogue and its predecessors are outlined and three straightforward applications are presented: (1) Completeness assessment: period distribution of SB1s and SB2s; (2) Shortest periods across the H-R diagram; (3) Period-eccentricity relation.Comment: Accepte for publication in A&A, 6 pages, 6 figure

The visual orbits of the spectroscopic binaries HD 6118 and HD 27483 from the Palomar Testbed Interferometer

We present optical interferometric observations of two double-lined spectroscopic binaries, HD 6118 and HD 27483, taken with the Palomar Testbed Interferometer (PTI) in the K band. HD 6118 is one of the most eccentric spectroscopic binaries and HD 27483 a spectroscopic binary in the Hyades open cluster. The data collected with PTI in 2001-2002 allow us to determine astrometric orbits and when combined with the radial velocity measurements derive all physical parameters of the systems. The masses of the components are 2.65 +/- 0.27 M_Sun and 2.36 +/- 0.24 M_Sun for HD 6118 and 1.38 +/- 0.13 M_Sun and 1.39 +/- 0.13 M_Sun for HD 27483. The apparent semi-major axis of HD 27483 is only 1.2 mas making it the closest binary successfully observed with an optical interferometer.Comment: submitted to Ap

Electrophysiological effects of nicotinic and electrical stimulation of intrinsic cardiac ganglia in the absence of extrinsic autonomic nerves in the rabbit heart

BackgroundThe intrinsic cardiac nervous system is a rich network of cardiac nerves that converge to form distinct ganglia and extend across the heart and is capable of influencing cardiac function.ObjectiveThe goals of this study were to provide a complete picture of the neurotransmitter/neuromodulator profile of the rabbit intrinsic cardiac nervous system and to determine the influence of spatially divergent ganglia on cardiac electrophysiology.MethodsNicotinic or electrical stimulation was applied at discrete sites of the intrinsic cardiac nerve plexus in the Langendorff-perfused rabbit heart. Functional effects on sinus rate and atrioventricular conduction were measured. Immunohistochemistry for choline acetyltransferase (ChAT), tyrosine hydroxylase, and/or neuronal nitric oxide synthase (nNOS) was performed using whole mount preparations.ResultsStimulation within all ganglia produced either bradycardia, tachycardia, or a biphasic brady-tachycardia. Electrical stimulation of the right atrial and right neuronal cluster regions produced the largest chronotropic responses. Significant prolongation of atrioventricular conduction was predominant at the pulmonary vein-caudal vein region. Neurons immunoreactive (IR) only for ChAT, tyrosine hydroxylase, or nNOS were consistently located within the limits of the hilum and at the roots of the right cranial and right pulmonary veins. ChAT-IR neurons were most abundant (1946 ± 668 neurons). Neurons IR only for nNOS were distributed within ganglia.ConclusionStimulation of intrinsic ganglia, shown to be of phenotypic complexity but predominantly of cholinergic nature, indicates that clusters of neurons are capable of independent selective effects on cardiac electrophysiology, therefore providing a potential therapeutic target for the prevention and treatment of cardiac disease

Three-dimensional CFD simulations with large displacement of the geometries using a connectivity-change moving mesh approach

This paper deals with three-dimensional (3D) numerical simulations involving 3D moving geometries with large displacements on unstructured meshes. Such simulations are of great value to industry, but remain very time-consuming. A robust moving mesh algorithm coupling an elasticity-like mesh deformation solution and mesh optimizations was proposed in previous works, which removes the need for global remeshing when performing large displacements. The optimizations, and in particular generalized edge/face swapping, preserve the initial quality of the mesh throughout the simulation. We propose to integrate an Arbitrary Lagrangian Eulerian compressible flow solver into this process to demonstrate its capabilities in a full CFD computation context. This solver relies on a local enforcement of the discrete geometric conservation law to preserve the order of accuracy of the time integration. The displacement of the geometries is either imposed, or driven by fluid–structure interaction (FSI). In the latter case, the six degrees of freedom approach for rigid bodies is considered. Finally, several 3D imposed-motion and FSI examples are given to validate the proposed approach, both in academic and industrial configurations

SB9: The ninth catalogue of spectroscopic binary orbits

The Ninth Catalogue of Spectroscopic Binary Orbits (http://sb9.astro.ulb.ac.be) continues the series of compilations of spectroscopic orbits carried out over the past 35 years by Batten and collaborators. As of 2004 May 1st, the new Catalogue holds orbits for 2386 systems. Some essential differences between this catalogue and its predecessors are out-lined and three straightforward applications are presented: (1) completeness assessment: period distribution of SB1s and SB2s; (2) shortest periods across the H-R diagram; (3) period-eccentricity relation.Facultad de Ciencias Astronómicas y Geofísica

Biochemical studies on Francisella tularensis RelA in (p)ppGpp Biosynthesis

2 ABSTRACT The bacterial stringent response is induced by nutrient deprivation and is mediated by enzymes of the RSH superfamily that control concentrations of the "alarmones" (p)ppGpp. This regulatory pathway is present in the vast majority of pathogens and has been proposed as a potential antibacterial target. Current understanding of RelA mediated responses are based on biochemical studies using Escherichia coli as a model. In comparison, the Francisella tularensis RelA sequence contains a truncated regulatory C-terminal region and an unusual synthetase motif (EXSD). Biochemical analysis of Francisella tularensis RelA showed the similarities and differences of this enzyme compared to the model RelA from Escherichia coli. Purification of the enzyme yielded a stable dimer capable of reaching concentrations of 10 mg/mL. In contrast to other enzymes from the RelA/SpoT homologue superfamily, activity assays with F. tularensis RelA demonstrate a high degree of specificity for GTP as a pyrophosphate acceptor, with no measurable turnover for GDP. Steady state kinetic analysis of F. tularensis RelA gave saturation activity curves that best fitted a sigmoidal function. This kinetic profile can result from allosteric regulation and further measurements with potential allosteric regulators demonstrated activation by ppGpp with an EC 50 of 60 ± 1.9 μM. Activation of F. tularensis RelA by stalled ribosomal complexes formed with ribosomes purified from Escherichia coli MRE600 was observed, but interestingly, significantly weaker activation with ribosomes isolated from Francisella philomiragia

The HgMn Binary Star Phi Herculis: Detection and Properties of the Secondary and Revision of the Elemental Abundances of the Primary

Observations of the Mercury-Manganese star Phi Herculis with the Navy Prototype Optical Interferometer (NPOI) conclusively reveal the previously unseen companion in this single-lined binary system. The NPOI data were used to predict a spectral type of A8V for the secondary star Phi Her B. This prediction was subsequently confirmed by spectroscopic observations obtained at the Dominion Astrophysical Observatory. Phi Her B is rotating at 50 +/-3 km/sec, in contrast to the 8 km/sec lines of Phi Her A. Recognizing the lines from the secondary permits one to separate them from those of the primary. The abundance analysis of Phi Her A shows an abundance pattern similar to those of other HgMn stars with Al being very underabundant and Sc, Cr, Mn, Zn, Ga, Sr, Y, Zr, Ba, Ce, and Hg being very overabundant.Comment: Accepted to ApJ, 45 pages, 11 figure