THE MANAGEMENT AND CAPITALIZATION OF THE LANDSCAPING POTENTIAL OF THE CRUCII SQUARE FROM TIMISOARA CITY

The Crucii Square is situated in the Elisabetin district in the city of Timisoara, in a residential area. According to a map from 1849, the current Crucii Square is situated on the very line of the building injunction circle around the fortress of Timisoara. The square name originates from an old cross which was preserved until today. Taking into the age of the oldest trees, the square was set as a green space after 1920. The current landscaping consists in tracing and slabbing the allies and building a new hero monument, also dates from after 1920. The square’s surface is of 6255mp. In the present paper we carried out an estimate of the green space and determined the current vegetation state, since green cadastre is the only way to determine the real state of green spaces belonging to a city’s patrimony, including parks and squares as well as the entire street vegetation (Ciupa et al., 2005). The paper‘s character is thus that of a vegetation fund inventory, as well as organisational design based on ecologic and landscaping criteria. The paper also comprises a square landscaping proposal, highlighting the site’s historic character and the high vegetation value

XPAD: pixel detector for material sciences

Currently available 2D detectors do not make full use of the high flux and high brilliance of third generation synchrotron sources. The XPAD prototype, using active pixels, has been developed to fulfil the needs of materials science scattering experiments. At the time, its prototype is build of eight modules of eight chips. The threshold calibration of /spl ap/4 10/sup 4/ pixels is discussed. Applications to powder diffraction or SAXS experiments prove that it allows to record high quality data

XPAD: A Photons Counting Pixel Detector for Material Sciences and Small Animal imaging

A paraître dans NIMInternational audienceExperiments on high flux and high brilliance 3rd generation synchrotron X-ray sources are now limited by detector performance. Photon counting hybrid pixel detectors are being investigated as a solution to improve the dynamic range and the readout speed of the available 2D detectors. The XPAD2 is a large surface hybrid pixel detector (68 x 65 mm$^2$) with a dynamic response which ranges from 0.01 photons/pixel/s up to 10$^6$ photons/pixel/s. High resolution data have been recorded using the XPAD2. The comparison with data measured using a conventional setup shows a gain on measurement duration by a factor 20 and on dynamic range. A new generation of pixel detector (XPAD3) is presently under development. For this, a new electronic chip (the XPAD3) has been designed to improve spatial resolution by using 130 $\mu$m pixels and detector efficiency by using CdTe sensors. XPAD2 is also operated with PIXSCAN, a CT-scanner for mice

Making subaltern shikaris: histories of the hunted in colonial central India

Academic histories of hunting or shikar in India have almost entirely focused on the sports hunting of British colonists and Indian royalty. This article attempts to balance this elite bias by focusing on the meaning of shikar in the construction of the Gond ‘tribal’ identity in late nineteenth and early twentieth-century colonial central India. Coining the term ‘subaltern shikaris’ to refer to the class of poor, rural hunters, typically ignored in this historiography, the article explores how the British managed to use hunting as a means of state penetration into central India’s forest interior, where they came to regard their Gond forest-dwelling subjects as essentially and eternally primitive hunting tribes. Subaltern shikaris were employed by elite sportsmen and were also paid to hunt in the colonial regime’s vermin eradication programme, which targeted tigers, wolves, bears and other species identified by the state as ‘dangerous beasts’. When offered economic incentives, forest dwellers usually willingly participated in new modes of hunting, even as impact on wildlife rapidly accelerated and became unsustainable. Yet as non-indigenous approaches to nature became normative, there was sometimes also resistance from Gond communities. As overkill accelerated, this led to exclusion of local peoples from natural resources, to their increasing incorporation into dominant political and economic systems, and to the eventual collapse of hunting as a livelihood. All of this raises the question: To what extent were subaltern subjects, like wildlife, ‘the hunted’ in colonial India

A case of minimal change nephrotic syndrome with immunoglobulin A nephropathy transitioned to focal segmental glomerulosclerosis

A 50-year-old woman with a 1-month history of lower extremity edema and a 5 kg weight increase was admitted to our hospital with suspected nephrotic syndrome in October 1999. Urine protein level was 3.5 g per day, 10-15 erythrocytes in urine per high-power field, and serum albumin level 2.5 g/dl. Furthermore, an accumulation of pleural effusion was confirmed by chest X-ray. The results of a renal biopsy indicated slight mesangial proliferation in the glomeruli by light microscopy, and an immunofluorescence study confirmed the deposition of immunoglobulin (Ig) A and C3 in the mesangial area. Diffuse attenuation of foot processes and dense deposits in the mesangial area were observed by electron microscopy. Treatment with 40 mg/day of prednisolone was effective, and proteinuria was negative 1 month later. Because of this course, we diagnosed minimal change nephrotic syndrome complicated by mild-proliferative IgA nephropathy. In November 2000, there was a relapse of nephrotic syndrome, which was believed to be induced by an influenza vaccination, but response to increased steroid treatment was favorable, and proteinuria disappeared on day 13 of steroid increase. A second relapse in May 2001, showed steroid resistance with renal insufficiency, and an increase in the selectivity index to 0.195. Light microscopy revealed focal sclerotic lesions of the glomeruli, and an immunofluorescence study revealed attenuation of mesangial IgA and C3 deposition. These findings led to the diagnosis that minimal change nephrotic syndrome had transitioned to focal segmental glomerulosclerosis, whereby mesangial IgA deposition was reduced by immunosuppressive treatment. Subsequently, her renal function gradually worsened to the point of end-stage renal failure by 27 months after the second relapse of nephrotic syndrome

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

Photo-reorganization of some 3-alkoxy-2-(alkoxyphenyl)chromones

685-691A photo-reorganization of 3-alkoxy-2-(alkoxyphenyl)chromones to the isomeric angular tetracyclic compounds through the 1,4-biradical generated by the excited carbonyl group through the γ-hydrogen abstraction has been described. Substituent effect of the 3-alkoxy group and the effect of position of alkoxy group in the 2-phenyl ring are explained