633 research outputs found
Measurement of the Crab nebula polarization at 90 GHz as a calibrator for CMB experiments
CMB experiments aiming at a precise measurement of the CMB polarization, such
as the Planck satellite, need a strong polarized absolute calibrator on the sky
to accurately set the detectors polarization angle and the cross-polarization
leakage. As the most intense polarized source in the microwave sky at angular
scales of few arcminutes, the Crab nebula will be used for this purpose. Our
goal was to measure the Crab nebula polarization characteristics at 90 GHz with
unprecedented precision. The observations were carried out with the IRAM 30m
telescope employing the correlation polarimeter XPOL and using two orthogonally
polarized receivers. We processed the Stokes I, Q, and U maps from our
observations in order to compute the polarization angle and linear polarization
fraction. The first is almost constant in the region of maximum emission in
polarization with a mean value of alpha_Sky=152.1+/-0.3 deg in equatorial
coordinates, and the second is found to reach a maximum of Pi=30% for the most
polarized pixels. We find that a CMB experiment having a 5 arcmin circular beam
will see a mean polarization angle of alpha_Sky=149.9+/-0.2 deg and a mean
polarization fraction of Pi=8.8+/-0.2%.Comment: Accepted for publication in A&A, 9 pages, 4 figure
Clathrin promotes incorporation of cargo into coated pits by activation of the AP2 adaptor mu 2 kinase
Endocytic cargo such as the transferrin receptor is incorporated into clathrin-coated pits by associating, via tyrosine-based motifs, with the AP2 complex. Cargo-AP2 interactions occur via the mu2 subunit of AP2, which needs to be phosphorylated for endocytosis to occur. The most likely role for mu2 phosphorylation is in cargo recruitment because mu2 phosphorylation enhances its binding to internalization motifs. Here, we investigate the control of mu2 phosphorylation. We identify clathrin as a specific activator of the mu2 kinase and, in permeabilized cells, we show that ligand sequestration, driven by exogenous clathrin, results in elevated levels of mu2 phosphorylation. Furthermore, we show that AP2 containing phospho-mu2 is mainly associated with assembled clathrin in vivo, and that the level of phospho-mu2 is strongly reduced in a chicken B cell line depleted of clathrin heavy chain. Our results imply a central role for clathrin in the regulation of cargo selection via the modulation of phospho-mu2 levels
Exclusive production in ultraperipheral Pb+Pb collisions to NLO pQCD
We present the first NLO pQCD study of coherent exclusive
photoproduction in ultraperipheral heavy-ion collisions (UPCs) at the LHC.
Taking the generalized parton distributions (GPDs) in their forward limit, as
parton distribution functions (PDFs), we quantify the NLO contributions in the
rapidity-differential cross section, show that the real part of the amplitude
must not be neglected, study the gluon and quark contributions, chart the
scale-choice and PDF uncertainties, and compare the NLO results with LHC and
HERA data. We show that the scale dependence is significant but a scale choice
can be found with which we reproduce the 2.76 and 5.02 TeV UPC data. In
particular, we show that the process is clearly more sensitive to the nuclear
quark PDFs than thought before.Comment: 5 pages, 5 figures, contributed talk by T.L. at the XXIX
International Conference on Ultra-relativistic Nucleus-Nucleus Collisions,
Quark Matter 2022, 4-10 April, 2022, Krakow, Polan
Comparison of T1 mapping techniques for ECV quantification. histological validation and reproducibility of ShMOLLI versus multibreath-hold T1 quantification equilibrium contrast CMR
BACKGROUND: Myocardial extracellular volume (ECV) is elevated in fibrosis or infiltration and can be quantified by measuring the haematocrit with pre and post contrast T1 at sufficient contrast equilibrium. Equilibrium CMR (EQ-CMR), using a bolus-infusion protocol, has been shown to provide robust measurements of ECV using a multibreath-hold T1 pulse sequence. Newer, faster sequences for T1 mapping promise whole heart coverage and improved clinical utility, but have not been validated.
METHODS: Multibreathhold T1 quantification with heart rate correction and single breath-hold T1 mapping using Shortened Modified Look-Locker Inversion recovery (ShMOLLI) were used in equilibrium contrast CMR to generate ECV values and compared in 3 ways.Firstly, both techniques were compared in a spectrum of disease with variable ECV expansion (n=100, 50 healthy volunteers, 12 patients with hypertrophic cardiomyopathy, 18 with severe aortic stenosis, 20 with amyloid). Secondly, both techniques were correlated to human histological collagen volume fraction (CVF%, n=18, severe aortic stenosis biopsies). Thirdly, an assessment of test:retest reproducibility of the 2 CMR techniques was performed 1 week apart in individuals with widely different ECVs (n=10 healthy volunteers, n=7 amyloid patients).
RESULTS: More patients were able to perform ShMOLLI than the multibreath-hold technique (6% unable to breath-hold). ECV calculated by multibreath-hold T1 and ShMOLLI showed strong correlation (r(2)=0.892), little bias (bias -2.2%, 95%CI -8.9% to 4.6%) and good agreement (ICC 0.922, range 0.802 to 0.961, p<0.0001). ECV correlated with histological CVF% by multibreath-hold ECV (r(2)= 0.589) but better by ShMOLLI ECV (r(2)= 0.685). Inter-study reproducibility demonstrated that ShMOLLI ECV trended towards greater reproducibility than the multibreath-hold ECV, although this did not reach statistical significance (95%CI -4.9% to 5.4% versus 95%CI -6.4% to 7.3% respectively, p=0.21).
CONCLUSIONS: ECV quantification by single breath-hold ShMOLLI T1 mapping can measure ECV by EQ-CMR across the spectrum of interstitial expansion. It is procedurally better tolerated, slightly more reproducible and better correlates with histology compared to the older multibreath-hold FLASH techniques
Exclusive J/psi : photoproduction in ultraperipheral Pb plus Pb collisions at the CERN Large Hadron Collider calculated at next-to-leading order perturbative QCD
We present the first next-to-leading-order (NLO) perturbative QCD (pQCD) study of rapidity-differential cross sections of coherent exclusive photoproduction of J/psi mesons in heavy-ion ultraperipheral collisions (UPCs) at the CERN Large Hadron Collider (LHC), d sigma /dy(Pb + Pb -> Pb + J/psi + Pb). For this, we account for the photon-nucleon NLO cross sections at the forward limit, the t dependence using a standard nuclear form factor, and the photon fluxes of the colliding nuclei. Approximating the generalized parton distributions with their forward-limit parton distribution functions (PDFs), we quantify the NLO contributions in the cross sections, show that the real part of the amplitude and quark-PDF contributions must not be neglected, quantify the uncertainties arising from the scale choice and PDFs, and compare our results with ALICE, CMS, and LHCb J/psi photoproduction data in Pb + Pb UPCs, exclusive J/psi photoproduction data from HERA, and LHCb data in p + p. The scale dependence in d sigma /dy(Pb + Pb & RARR; Pb + J/psi + Pb) is significant, but we can find a scale choice that reproduces the Pb + Pb UPC data at both 2.76 and 5.02 TeV collision energies. This process has traditionally been suggested to be a direct probe of nuclear gluon distributions. We show that the situation changes rather dramatically from LO to NLO: the NLO cross sections reflect the nuclear effects of both gluons and quarks in a complicated manner, where the relative signs of the LO and NLO terms in the amplitude play a significant role.Peer reviewe
The Role of Personality Traits in Young Adult Fruit and Vegetable Consumption
This project investigated how individual differences in the big-five personality traits (neuroticism, extraversion, openness to experience, conscientiousness, and agreeableness) predicted plant-food consumption in young adults. A total of 1073 participants from two samples of young adults aged 17â25 reported their daily servings of fruits, vegetables, and two unhealthy foods for comparison purposes using an Internet daily diary for 21 or 13 days (micro-longitudinal, correlational design). Participants also completed the Neuroticism, Extraversion, Openness Five Factor Inventory (NEO-FFI) measure of personality, and demographic covariates including gender, age, ethnicity, and body mass index (BMI). Analyses used hierarchical regression to predict average daily fruit and vegetable consumption as separate dependent variables from the demographic covariates (step 1) and the five personality traits (step 2). Results showed that young adults higher in openness and extraversion, and to some extent conscientiousness, ate more fruits and vegetables than their less open, less extraverted, and less conscientious peers. Neuroticism and agreeableness were unrelated to fruit and vegetable consumption. These associations were unique to eating fruit and vegetables and mostly did not extend to unhealthy foods tested. Young adult women also ate more fruit and vegetables than young adult men. Results suggest that traits associated with greater intellect, curiosity, and social engagement (openness and extraversion), and to a lesser extent, discipline (conscientiousness) are associated with greater plant-food consumption in this population. Findings reinforce the importance of personality in establishing healthy dietary habits in young adulthood that could translate into better health outcomes later in life
Perfectionism, achievement motives, and attribution of success and failure in female soccer players
While some researchers have identified adaptive perfectionism as a key characteristic to achieving elite performance in sport, others see perfectionism as a maladaptive characteristic that undermines, rather than helps, athletic performance. Arguing that perfectionism in sport contains both adaptive and maladaptive facets, the present article presents a study of N 5 74 female soccer players investigating how two facets of perfectionismâperfectionistic strivings and negative reactions to imperfection (Stoeber, Otto, Pescheck, Becker, & Stoll, 2007)âare related to achievement motives and attributions of success and failure. Results show that striving for perfection was related to hope of success and self-serving attributions (internal attribution of success). Moreover, once overlap between the two facets of perfectionism was controlled for, striving for perfection was inversely related to fear of failure and self-depreciating attributions (internal attribution of failure). In contrast,
negative reactions to imperfection were positively related to fear of failure and self-depreciating attributions (external attribution of success) and inversely related to self-serving attributions (internal attribution of success and external attribution of failure). It is concluded that striving for perfection in sport is associated with an adaptive pattern of positive motivational orientations and self-serving attributions of success and failure, which
may help athletic performance. In contrast, negative reactions to imperfection are associated with a maladaptive
pattern of negative motivational orientations and self-depreciating attributions, which is likely to undermine athletic performance. Consequently, perfectionism in sport may be adaptive in those athletes who strive for perfection, but can control their negative reactions when performance is less than perfect
Perfectionism and achievement goals in young Finnish ice-hockey players aspiring to make the Under-16 national team
Research on perfectionism suggests that is it useful to differentiate between perfectionistic strivings and perfectionistic concerns. Regarding the 2 x 2 achievement goal framework, the usefulness of this differentiation was recently demonstrated in a study with university student athletes (Stoeber, Stoll, Pescheck, & Otto, 2008, Study 2), in which it was found that perfectionistic strivings were associated with mastery-approach and performance-approach goals and perfectionistic concerns with mastery-avoidance, performance-approach, and performance-avoidance goals. Because the study was largely exploratory and only used non-elite athletes, the aim of the present research was to replicate and extend these findings by investigating a sample of 138 young, elite ice-hockey players, while adding further measures of perfectionism and using structural equation modelling (SEM) to confirm the relationships between perfectionistic strivings, perfectionistic concerns,and the 2 x 2 achievement goals. The SEM results showed that, in elite athletes also, perfectionistic strivings are associated with mastery-approach and performance-approach goals, whereas perfectionistic concerns are associated with masteryavoidance,
performance-approach, and performance-avoidance goals. Our findings corroborate the importance of differentiating between perfectionistic strivings and perfectionistic concerns when studying perfectionism in sports, because
only perfectionistic concerns (and not perfectionistic strivings) are associated with maladaptive patterns of achievement goals
Perfectionism and psychological distress: A modeling approach to understanding their therapeutic relationship
The present study assessed the effectiveness of a web-based psychoeducational intervention protocol for decreasing levels of perfectionism and psychological distress. Different levels of therapeutic intervention (no treatment, general stress management intervention, general stress management intervention plus cognitive behavioral intervention) were provided to perfectionistic participants over a 10-week period. It was found via a longitudinal structural equation model that higher levels of therapeutic intervention predicted greater improvements in perfectionism and psychological distress. Further, amount of improvement in trait perfectionism and perfectionistic automatic thoughts was highly related to amount of improvement in psychological distress. The findings attest to the potential usefulness of a web-based intervention that combines a general stress management intervention with a cognitive behavioral intervention.Social Sciences and Humanities Research Council (SSHRC
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