The entanglement in one-dimensional random XY spin chain with Dzyaloshinskii-Moriya interaction

The impurities of exchange couplings, external magnetic fields and Dzyaloshinskii--Moriya (DM) interaction considered as Gaussian distribution, the entanglement in one-dimensional random $XY$ spin systems is investigated by the method of solving the different spin-spin correlation functions and the average magnetization per spin. The entanglement dynamics at central locations of ferromagnetic and antiferromagnetic chains have been studied by varying the three impurities and the strength of DM interaction. (i) For ferromagnetic spin chain, the weak DM interaction can improve the amount of entanglement to a large value, and the impurities have the opposite effect on the entanglement below and above critical DM interaction. (ii) For antiferromagnetic spin chain, DM interaction can enhance the entanglement to a steady value. Our results imply that DM interaction strength, the impurity and exchange couplings (or magnetic field) play competing roles in enhancing quantum entanglement.Comment: 12 pages, 3 figure

The Vela Pulsar and its Synchrotron Nebula

(Abridged) We present high-resolution Chandra X-ray observations of PSR B0833-45, the 89 ms pulsar associated with the Vela supernova remnant. We have acquired two observations separated by one month to search for changes in the pulsar and its environment following an extreme glitch in its rotation frequency. We find a well-resolved nebula with a toroidal morphology remarkably similar to that observed in the Crab Nebula, along with an axial Crab-like jet. Between the two observations the flux from the pulsar is found to be steady to within 0.75%; the 3 sigma limit on the fractional increase in the pulsar's X-ray flux is < ~10^-5 of the inferred glitch energy. We use this limit to constrain parameters of glitch models and neutron star structure. We do find a significant increase in the flux of the nebula's outer arc; if associated with the glitch, the inferred propagation velocity is > 0.7c, similar to that seen in the brightening of the Crab Nebula wisps. We propose an explanation for the X-ray structure of the Vela synchrotron nebula based on a model originally developed for the Crab Nebula. In a departure from the Crab model, the magnetization parameter "sigma" of the Vela pulsar wind is allowed to be of order unity; this is consistent with the simplest MHD transport of magnetic field from the pulsar to the nebula, where B < 4 X 10^-4 G. We review effects that may enhance the probability of alignment between the spin axis and space velocity of a pulsar, and speculate that short-period, slowly moving pulsars are just the ones best-suited to producing synchrotron nebulae with such aligned structures.Comment: 16 pages with 8 figures, uses LaTex, emulateapj.sty. Refereed version. To appear in The Astrophysical Journa

Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2

Aberrant mechanotransduction and compromised epithelial barrier function are associated with numerous human pathologies including inflammatory skin disorders. However, the cytoskeletal mechanisms regulating inflammatory responses in the epidermis are not well understood. Here we addressed this question by inducing a psoriatic phenotype in human keratinocytes and reconstructed human epidermis using a cytokine stimulation model. We show that the inflammation upregulates the Rho-myosin II pathway and destabilizes adherens junctions (AJs) promoting YAP nuclear entry. The integrity of cell-cell adhesion but not the myosin II contractilityper seis the determinative factor for the YAP regulation in epidermal keratinocytes. The inflammation-induced disruption of AJs, increased paracellular permeability, and YAP nuclear translocation are regulated by ROCK2, independently from myosin II activation. Using a specific inhibitor KD025, we show that ROCK2 executes its effects via cytoskeletal and transcription-dependent mechanisms to shape the inflammatory response in the epidermis

Monte Carlo Simulations of Globular Cluster Evolution. III. Primordial Binary Interactions

We study the dynamical evolution of globular clusters using our 2D Monte Carlo code with the inclusion of primordial binary interactions for equal-mass stars. We use approximate analytical cross sections for energy generation from binary-binary and binary-single interactions. After a brief period of slight contraction or expansion of the core over the first few relaxation times, all clusters enter a much longer phase of stable "binary burning" lasting many tens of relaxation times. The structural parameters of our models during this phase match well those of most observed globular clusters. At the end of this phase, clusters that have survived tidal disruption undergo deep core collapse, followed by gravothermal oscillations. Our results clearly show that the presence of even a small fraction of binaries in a cluster is sufficient to support the core against collapse significantly beyond the normal core collapse time predicted without the presence of binaries. For tidally truncated systems, collapse is easily delayed sufficiently that the cluster will undergo complete tidal disruption before core collapse. As a first step toward the eventual goal of computing all interactions exactly using dynamical three- and four-body integration, we have incorporated an exact treatment of binary-single interactions in our code. We show that results using analytical cross sections are in good agreement with those using exact three-body integration, even for small binary fractions where binary-single interactions are energetically most important.Comment: Accepted for publication in ApJ. Minor changes to reflect accepted version. 28 pages, 17 figures; some figures low resolution. Full resolution paper available at http://www.mit.edu/~fregeau/paper3.pd

Remnant radio-loud AGN in the Herschel-ATLAS field

Only a small fraction of observed active galactic nuclei (AGN) display large-scale radio emission associated with jets, yet these radio-loud AGN have become increasingly important in models of galaxy evolution. In determining the dynamics and energetics of the radio sources over cosmic time, a key question concerns what happens when their jets switch off. The resulting ‘remnant' radio-loud AGN have been surprisingly evasive in past radio surveys, and therefore statistical information on the population of radio-loud AGN in their dying phase is limited. In this paper, with the recent developments of Low-Frequency Array (LOFAR) and the Very Large Array, we are able to provide a systematically selected sample of remnant radio-loud AGN in the Herschel-ATLAS field. Using a simple core-detection method, we constrain the upper limit on the fraction of remnants in our radio-loud AGN sample to 9 per cent, implying that the extended lobe emission fades rapidly once the core/jets turn off. We also find that our remnant sample has a wide range of spectral indices (−1.5 ⩽ α1400150 ⩽ −0.5), confirming that the lobes of some remnants may possess flat spectra at low frequencies just as active sources do. We suggest that, even with the unprecedented sensitivity of LOFAR, our sample may still only contain the youngest of the remnant population

A LOFAR-IRAS cross-match study : the far-infrared radio correlation and the 150-MHz luminosity as a star-formation rate

13 pages, 13 figures, accepted for publication in A&A, © ESO 2019Aims. We aim to study the far-infrared radio correlation (FIRC) at 150 MHz in the local Universe (at a median redshift z~0:05) and improve the use of the rest-frame 150-MHz luminosity, L150, as a star-formation rate (SFR) tracer, which is unaffected by dust extinction. Methods. We cross-match the 60-um selected Revised IRAS Faint Source Survey Redshift (RIFSCz) catalogue and the 150-MHz selected LOFAR value-added source catalogue in the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX) Spring Field. We estimate L150 for the cross-matched sources and compare it with the total infrared (IR) luminosity, LIR, and various SFR tracers. Results. We find a tight linear correlation between log L150 and log LIR for star-forming galaxies, with a slope of 1.37. The median qIR value (defined as the logarithm of the LIR to L150 ratio) and its rms scatter of our main sample are 2.14 and 0.34, respectively. We also find that log L150 correlates tightly with the logarithm of SFR derived from three different tracers, i.e., SFR_Halpha based on the Halpha line luminosity, SFR_60 based on the rest-frame 60-um luminosity and SFR_IR based on LIR, with a scatter of 0.3 dex. Our best-fit relations between L150 and these SFR tracers are, log L150 (Lsun) = 1.35(0.06) x log SFR_Halpha (Msun/yr) + 3.20(0.06), log L150 (Lsun) = 1.31(0.05) x log SFR_60 (Msun/yr) + 3.14(0.06), and log L150 (Lsun) = 1.37(0.05) x log SFR_IR (Msun/yr) + 3.09(0.05), which show excellent agreement with each other.Peer reviewedFinal Accepted Versio

Factor XII and Upar Upregulate Neutrophil Functions to Influence Wound Healing

Coagulation factor XII (FXII) deficiency is associated with decreased neutrophil migration, but the mechanisms remain uncharacterized. Here, we examine how FXII contributes to the inflammatory response. In 2 models of sterile inflammation, FXII-deficient mice (F12–/–) had fewer neutrophils recruited than WT mice. We discovered that neutrophils produced a pool of FXII that is functionally distinct from hepatic-derived FXII and contributes to neutrophil trafficking at sites of inflammation. FXII signals in neutrophils through urokinase plasminogen activator receptor–mediated (uPAR-mediated) Akt2 phosphorylation at S474 (pAktS474). Downstream of pAkt2S474, FXII stimulation of neutrophils upregulated surface expression of αMβ2 integrin, increased intracellular calcium, and promoted extracellular DNA release. The sum of these activities contributed to neutrophil cell adhesion, migration, and release of neutrophil extracellular traps in a process called NETosis. Decreased neutrophil signaling in F12–/– mice resulted in less inflammation and faster wound healing. Targeting hepatic F12 with siRNA did not affect neutrophil migration, whereas WT BM transplanted into F12–/– hosts was sufficient to correct the neutrophil migration defect in F12–/– mice and restore wound inflammation. Importantly, these activities were a zymogen FXII function and independent of FXIIa and contact activation, highlighting that FXII has a sophisticated role in vivo that has not been previously appreciated

Long term follow up results of sequential left internal thoracic artery grafts on severe left anterior descending artery disease

<p>Abstract</p> <p>Purpose</p> <p>Several alternative procedures have been proposed to achieve complete revascularization in the presence of diffuse left anterior descending coronary artery (LAD) disease. With the extensive use of internal thoracic artery grafts in coronary artery bypass procedures, sequential anastomosis of the left internal thoracic artery (LITA) to LAD has gained popularity in these challenging cases. The long term results of sequential LITA to LAD anstomosis were examined in this study.</p> <p>Patients and Methods</p> <p>In order to determine the long term results of the sequential revascularization of LAD by LITA graft, 41 out of 49 patients operated between January 2001 and December 2005 were selected for control coronary arteriography. The median period for control coronary arteriography was 64 months.</p> <p>Results</p> <p>Seventy five anastomoses were found to be fully patent (91,46%) among the 82 sequential LITA anastomoses (41 LITA grafts) on the LAD at a median follow-up period of 64 months (53 to 123 months). Among the 41 LITA grafts used for this purpose, 36 were found intact (complete patency of the proximal and distal anastomoses) (87,8%). Two LITA grafts (4 anastomoses) were found to be totally occluded (4,87%). The proximal anastomosis of the LITA graft was observed to be 90% stenotic in one patient (1,21%). In one patient tight stenosis of the distal anastomosis line was observed (1,21%), while in another patient 70% narrowing of LITA lumen after the proximal anastomosis was detected (1,21%).</p> <p>Conclusion</p> <p>We strongly beleive that sequential LITA grafting of LAD is a safe alternative in the presence of severe LAD disease to achieve complete revascularization of the anterior myocardium with patency rates not much differing from conventional single LITA to LAD anastomosis.</p

The bright end of the infrared luminosity functions and the abundance of hyperluminous infrared galaxies

16 pages, 11 figures, accepted for publication in A&A as part of the LOFAR Deep Fields Paper Splash. © 2020 The European Southern Observatory (ESO)We provide the most accurate estimate yet of the bright end of the infrared (IR) luminosity functions (LFs) and the abundance of hyperluminous IR galaxies (HLIRGs) with IR luminosities > 10^13 L_solar, thanks to the combination of the high sensitivity, angular resolution, and large area of the LOFAR Deep Fields, which probes an unprecedented dynamic range of luminosity and volume. We cross-match Herschel sources and LOFAR sources in Bootes (8.63 deg^2), Lockman Hole (10.28 deg^2), and ELAIS-N1 (6.74 deg^2) with rms sensitivities of around 32, 22, and 20 mJy per beam, respectively. We divide the matched samples into unique and multiple categories. For the multiple matches, we de-blend the Herschel fluxes using the LOFAR positions and the 150-MHz flux densities as priors. We perform spectral energy distribution (SED) fitting, combined with multi-wavelength counterpart identifications and photometric redshift estimates, to derive IR luminosities. The depth of the LOFAR data allows us to identify highly complete (around 92% completeness) samples of bright Herschel sources with a simple selection based on the 250 micron flux density (45, 40, and 35 mJy in Bootes, Lockman Hole, and ELAIS-N1, respectively). Most of the bright Herschel sources fall into the unique category (i.e. a single LOFAR counterpart). For the multiple matches, there is excellent correspondence between the radio emission and the far-IR emission. We find a good agreement in the IR LFs with a previous study out to z around 6 which used de-blended Herschel data. Our sample gives the strongest and cleanest indication to date that the population of HLIRGs has surface densities of around 5 to 18 / deg^2 (with variations due to a combination of the applied flux limit and cosmic variance) and an uncertainty of a factor of 2. In comparison, the GALFORM semi-analytic model significantly under-predicts the abundance of HLIRGs.Peer reviewe