230 research outputs found
Regional brain development analysis through registration using anisotropic similarity, a constrained affine transformation
We propose a novel method to quantify brain growth in 3 arbitrary orthogonal directions of the brain or its sub-regions through linear registration. This is achieved by introducing a 9 degrees of freedom (dof) transformation called anisotropic similarity which is an affine transformation with constrained scaling directions along arbitrarily chosen orthogonal vectors. This gives the opportunity to extract scaling factors describing brain growth along those directions by registering a database of subjects onto a common reference. This information about directional growth brings insights that are not usually available in longitudinal volumetric analysis. The interest of this method is illustrated by studying the anisotropic regional and global brain development of 308 healthy subjects betwen 0 and 19 years old. A gender comparison of those scaling factors is also performed for four age-intervals. We demonstrate through these applications the stability of the method to the chosen reference and its ability to highlight growth differences accros regions and gender
Have you forgotten? A method to assess if machine learning models have forgotten data
In the era of deep learning, aggregation of data from several sources is a
common approach to ensuring data diversity. Let us consider a scenario where
several providers contribute data to a consortium for the joint development of
a classification model (hereafter the target model), but, now one of the
providers decides to leave. This provider requests that their data (hereafter
the query dataset) be removed from the databases but also that the model
`forgets' their data. In this paper, for the first time, we want to address the
challenging question of whether data have been forgotten by a model. We assume
knowledge of the query dataset and the distribution of a model's output. We
establish statistical methods that compare the target's outputs with outputs of
models trained with different datasets. We evaluate our approach on several
benchmark datasets (MNIST, CIFAR-10 and SVHN) and on a cardiac pathology
diagnosis task using data from the Automated Cardiac Diagnosis Challenge
(ACDC). We hope to encourage studies on what information a model retains and
inspire extensions in more complex settings.Comment: Accepted by MICCAI 202
Wave Function Microscopy of Quasibound Atomic States
In the 1980s Demkov, Kondratovich, and Ostrovsky and Kondratovich and
Ostrovsky proposed an experiment based on the projection of slow electrons
emitted by a photoionized atom onto a position-sensitive detector. In the case
of resonant excitation, they predicted that the spatial electron distribution
on the detector should represent nothing else but a magnified image of the
projection of a quasibound electronic state. By exciting lithium atoms in the
presence of a static electric field, we present in this Letter the first
experimental photoionization wave function microscopy images where signatures
of quasibound states are evident. Characteristic resonant features, such as
(i) the abrupt change of the number of wave function nodes across a resonance
and (ii) the broadening of the outer ring of the image (associated with
tunneling ionization), are observed and interpreted via wave packet
propagation simulations and recently proposed resonance tunneling mechanisms.
The electron spatial distribution measured by our microscope is a direct
macroscopic image of the projection of the microscopic squared modulus of the
electron wave that is quasibound to the atom and constitutes the first
experimental realization of the experiment proposed 30 years ago
Wave-function imaging of quasibound and continuum Stark states
Photoionization of an atom in the presence of a uniform static electric field
provides the unique opportunity to expand and visualize the atomic wave
function at a macroscopic scale. In a number of seminal publications dating
back to the 1980s, Fabrikant, Demkov, Kondratovich, and Ostrovsky showed that
this goal could be achieved by projecting slow (meV) photoionized electrons
onto a position-sensitive detector and underlined the distinction between
continuum and resonant contributions. The uncovering of resonant signatures
was achieved fairly recently in experiments on the nonhydrogenic lithium atoms
[Cohen et al., Phys. Rev. Lett. 110, 183001 (2013)]. The purpose of the
present article is the general description of these findings, with emphasis on
the various manifestations of resonant character. From this point of view,
lithium has been chosen as an illustrative example between the two limiting
cases of hydrogen, where resonance effects are more easily identified, and
heavy atoms like xenon, where resonant effects were not observed
ATLID Beam Steering Mechanism and derived new piezoelectric based devices for optical applications
ABSTRACT In Space & Defence (as well as in many others fields), there is a trend for miniaturisation in active optics requiring new actuators. Applications also often require the ability to withstand high vibrations and shocks levels, as well as vacuum compatibility for space applications. A new generation of small and smart actuators such as piezoelectric (piezo) actuators, are resolving this trend, thanks to their capacity to offer high energy density and to support both extreme and various requirements. This paper first presents the BSM mechanism and its requirements, the technologies involved in the design and the validation campaign results. Secondly, a derived XY piezoelectric positioning stage based on the same APA® and associated Strain Gage sensing technology is presented with its associated performances. Finally, a new piezoelectric motor based on the APA® technology, which allows the combination of long stroke while maintaining high resolution positioning of optical elements, is presented with experimental performances
Group testing with Random Pools: Phase Transitions and Optimal Strategy
The problem of Group Testing is to identify defective items out of a set of
objects by means of pool queries of the form "Does the pool contain at least a
defective?". The aim is of course to perform detection with the fewest possible
queries, a problem which has relevant practical applications in different
fields including molecular biology and computer science. Here we study GT in
the probabilistic setting focusing on the regime of small defective probability
and large number of objects, and . We construct and
analyze one-stage algorithms for which we establish the occurrence of a
non-detection/detection phase transition resulting in a sharp threshold, , for the number of tests. By optimizing the pool design we construct
algorithms whose detection threshold follows the optimal scaling . Then we consider two-stages algorithms and analyze their
performance for different choices of the first stage pools. In particular, via
a proper random choice of the pools, we construct algorithms which attain the
optimal value (previously determined in Ref. [16]) for the mean number of tests
required for complete detection. We finally discuss the optimal pool design in
the case of finite
Image guidance in neurosurgical procedures, the "Visages" point of view.
This paper gives an overview of the evolution of clinical
neuroinformatics in the domain of neurosurgery. It shows how
image guided neurosurgery (IGNS) is evolving according to the integration of new imaging modalities before, during and after the surgical procedure and how this acts as the premise of the Operative Room of the future. These different issues, as addressed by the VisAGeS INRIA/INSERM U746 research team (http://www.irisa.fr/visages), are presented and discussed in order to exhibit the benefits of an integrated work between physicians (radiologists, neurologists and neurosurgeons) and computer scientists to give adequate answers toward a more effective use of
images in IGNS
TERRISCOPE: AN OPTICAL REMOTE SENSING RESEARCH PLATFORM USING AIRCRAFT AND UAS FOR THE CHARACTERIZATION OF CONTINENTAL SURFACES
ONERA is developing TERRISCOPE, a new platform to characterize the environment and the continental surfaces by optical remote sensing using manned aircrafts and UAS (Unmanned Airborne System). The objective of TERRISCOPE is to make available to the scientific community combinations of optical measurements remotely sensed with the best level state-of-the-art sensors. Different kinds of sensors have already been acquired or are still being acquired: Hyperspectral sensors (0.5–2.5 μm range), visible high resolution cameras, multispectral infrared cameras and airborne laser scanners. Each sensor is declined in two versions: one high performance for manned aircrafts and one more compact for UAS. This paper describes the whole equipment, and presents the main characteristics and performances of the carriers, the sensors and the processing chain. Possible sensors combinations on airplanes and UAS are also presented, as well as preliminary results
Carbon K-edge x-ray emission spectroscopy of gas phase ethylenic molecules
We report on the C K-edge x-ray absorption spectra and the resonant (RXES) and non-resonant (NXES) x-ray emission spectra of ethylene, allene and butadiene in the gas phase. The RXES and NXES show clear differences for the different molecules. Overall both types of spectra are more structured for ethylene and allene, than for butadiene. Using density functional theory–restricted open shell configuration interaction single calculations, we simulate the spectra with remarkable agreement with the experiment. We identify the spectral features as being due to transitions involving localised 1s orbitals. For allene, there are distinct spectral bands that reflect transitions predominantly from either the central or terminal carbon atoms. These results are discussed in the context of ultrafast x-ray studies aimed at detecting the passage through conical intersections in polyatomic molecules
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XUV excitation followed by ultrafast non-adiabatic relaxation in PAH molecules as a femto-astrochemistry experiment
Highly excited molecular species are at play in the chemistry of interstellar media and are involved in the creation of radiation damage in a biological tissue. Recently developed ultrashort extreme ultraviolet light sources offer the high excitation energies and ultrafast time-resolution required for probing the dynamics of highly excited molecular states on femtosecond (fs) (1 fs=10−15s) and even attosecond (as) (1 as=10−18 s) timescales. Here we show that polycyclic aromatic hydrocarbons (PAHs) undergo ultrafast relaxation on a few tens of femtoseconds timescales, involving an interplay between the electronic and vibrational degrees of freedom. Our work reveals a general property of excited radical PAHs that can help to elucidate the assignment of diffuse interstellar absorption bands in astrochemistry, and provides a benchmark for the manner in which coupled electronic and nuclear dynamics determines reaction pathways in large molecules following extreme ultraviolet excitation
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