1,397 research outputs found

    Associations between reaction time measures and white matter hyperintensities in very old age.

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    In old age, a relationship has been reported between intraindividual variability (IIV) in reaction time and white matter integrity as evidenced by white matter hyperintensities (WMH). However, it is unclear how far such associations are due to incipient neurodegenerative pathology in the samples investigated. The present study examined the relationship between IIV and WMH in older individuals (N=526) drawn from the Sydney Memory and Ageing Study. Using a complex reaction time (RT) task, greater IIV and mean-RT were related to a higher WMH burden in the frontal lobe. Critically, significant associations remained having taken future dementia into account suggesting that they were not explained by incipient dementia. Additionally, independent measures of executive function accounted for the association between RT metrics and WHM. The results are consistent with the view that frontally-supported cognitive processes are involved in IIV-WMH relations, and that RT measures are sensitive to compromise in white matter structures in non-demented older individuals

    Measurement of the analyzing power of proton-carbon elastic scattering in the CNI region at RHIC

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    The single transverse spin asymmetry, A_N, of the p-carbon elastic scattering process in the Coulomb Nuclear Interference (CNI) region was measured using an ultra thin carbon target and polarized proton beam in the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory (BNL). In 2004, data were collected to calibrate the p-carbon process at two RHIC energies (24 GeV, 100 GeV). A_N was obtained as a function of momentum transfer -t. The results were fit with theoretical models which allow us to assess the contribution from a hadronic spin flip amplitude.Comment: Contribution to the proceedings of the 16th International Spin Physics Symposium, spin2004 (Trieste

    Trends in diabetic retinopathy screening attendance and associations with vision impairment attributable to diabetes in a large nationwide cohort

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    AIMS: To investigate diabetic retinopathy screening attendance and trends in certified vision impairment caused by diabetic eye disease. METHODS: This was a retrospective study of attendance in three urban UK diabetic eye screening programmes in England. A survival analysis was performed to investigate time from diagnosis to first screen by age and sex. Logistic regression analysis of factors influencing screening attendance during a 15-month reporting period was conducted, as well as analysis of new vision impairment certifications (Certificate of Vision Impairment) in England and Wales from 2009 to 2019. RESULTS: Of those newly registered in the Routine Digital Screening pathway (n = 97 048), 80% attended screening within the first 12 months and 88% by 36 months. Time from registration to first eye screening was longer for people aged 18-34 years, and 20% were unscreened after 3 years. Delay in first screen was associated with increased risk of referable retinopathy. Although 95% of participants (n = 291 296) attended during the 15-month reporting period, uptake varied considerably. Younger age, social deprivation, ethnicity and duration of diabetes were independent predictors of non-attendance and referable retinopathy. Although the last 10 years has seen an overall reduction in vision impairment certification attributable to diabetic eye disease, the incidence of vision impairment in those aged <35 years was unchanged. CONCLUSIONS: Whilst the majority of participants are screened in a timely manner, there is considerable variation in uptake. Young adults, have sub-optimal attendance, and levels of vision impairment in this population have not changed over the last 10 years. There is an urgent need to explore barriers to/enablers of attendance in this group to inform policy initiatives and tailored interventions to address this issue

    Measurement of the analyzing power in pp elastic scattering in the peak CNI region at RHIC

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    We report the first measurements of the A_N absolute value and shape in the -t range from 0.0015 to 0.010GeV/c^2 with a precision better than 0.005 for each A_N data point using a polarized atomic hydrogen gas jet target and the 100 GeV RHIC proton beam.Comment: 4 pages, 5 figure

    Measurement of quasi-elastic 12C(p,2p) scattering at high momentum transfer

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    We measured the high-momentum quasi-elastic 12C(p,2p) reaction (at center of mass angle near 90 degrees) for 6 and 7.5 GeV/c incident protons. The three-momentum components of both final state protons were measured and the missing energy and momentum of the target proton in the nucleus were determined. The validity of the quasi-elastic picture was verified up to Fermi momenta of about 450 MeV/c, where it might be questionable. Transverse and longitudinal Fermi momentum distributions of the target proton were measured and compared to independent particle models which do not reproduce the large momentum tails. We also observed that the transverse Fermi distribution gets wider as the longitudinal component increases in the beam direction, in contrast to a simple Fermi gas model.Comment: 4 pages including 3 figure

    RHIC polarimetry

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    Polarimeters were developed to measure the polarization of the proton beam at RHIC in relative scale through the asymmetry measurement of the elastic proton-carbon scattering. Recoil carbon ions with kinetic energy of 400 ≀ E ≀ 900 keV were detected by silicon strip detectors installed at 90° with respect to the beam. The absolute polarization is given by normalizing against another polarimeter implemented at RHIC, namely a polarized hydrogen gas jet polarimeter. In this report, the details of polarization measurements, data analysis, and systematic uncertainties are discussed based on the data taken during ∫s = 200 GeV operation of Run 05 at RHIC

    IMF dependence of Saturn's auroras: modelling study of HST and Cassini data from 12–15 February 2008

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    To gain better understanding of auroral processes in Saturn's magnetosphere, we compare ultraviolet (UV) auroral images obtained by the Hubble Space Telescope (HST) with the position of the open-closed field line boundary in the ionosphere calculated using a magnetic field model that employs Cassini measurements of the interplanetary magnetic field (IMF) as input. Following earlier related studies of pre-orbit insertion data from January 2004 when Cassini was located ~ 1300 Saturn radii away from the planet, here we investigate the interval 12–15 February 2008, when UV images of Saturn's southern dayside aurora were obtained by the HST while the Cassini spacecraft measured the IMF in the solar wind just upstream of the dayside bow shock. This configuration thus provides an opportunity, unique to date, to determine the IMF impinging on Saturn's magnetosphere during imaging observations, without the need to take account of extended and uncertain interplanetary propagation delays. The paraboloid model of Saturn's magnetosphere is then employed to calculate the magnetospheric magnetic field structure and ionospheric open-closed field line boundary for averaged IMF vectors that correspond, with appropriate response delays, to four HST images. We show that the IMF-dependent open field region calculated from the model agrees reasonably well with the area lying poleward of the UV emissions, thus supporting the view that the poleward boundary of Saturn's auroral oval in the dayside ionosphere lies adjacent to the open-closed field line boundary
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