Avaliação da sustentabilidade da suinocultura: um estudo em Santa Catarina, Brasil

This study aimed to identify the sustainability practices of pig creation on rural properties in the West region of the state of Santa Catarina, Brazil. The analysis included the system of sustainability indicators in pig farming. Although managers comply with the regulations and legislation, there are practical difficulties related to the destination of production waste, water use, expenditure controls, and social interaction. The sustainability analysis allowed investigating 30 properties and using a scale of 0-10 points, rate factors related to organizational, social, and environmental practices. Nine rural properties had a general performance, indicating characteristics of in search for sustainability, while 21 obtained a performance between 2.5 and 5.0 points, indicating fragilities in organizational, environmental, and social practices. It highlights the importance of analyzing sustainability indicators as a mechanism to control and implement better practices to assist in the search for sustainable development.O objetivo deste estudo foi identificar práticas sustentáveis de produção de suínos em áreas rurais da região oeste do estado de Santa Catarina no Brasil. Foi analisado o sistema de indicadores de sustentabilidade na suinocultura. Embora os gestores cumpram regras e regulamentos, existem dificuldades práticas com a alocação de resíduos de produção, consumo de água, controle de gastos e interações sociais. A análise de sustentabilidade nos permite pegar um total de 30 propriedades e usar uma escala de 0 a 10 pontos para avaliar fatores relacionados a práticas organizacionais, sociais e ambientais. Nove propriedades rurais obtiveram pontuação geral indicando as características de busca do desenvolvimento sustentável, enquanto 21 pontuaram entre 2,5 e 5,0, indicando a fragilidade das práticas organizacionais, ambientais e sociais. Salienta a importância da análise de indicadores de sustentabilidade como mecanismo de controle e implementação de melhores práticas para moderar o desenvolvimento sustentável

Molecular simulations of carbohydrates and protein–carbohydrate interactions: motivation, issues and prospects

The characterization of the 3D structure of oligosaccharides, their conjugates and analogs is particularly challenging for traditional experimental methods. Molecular simulation methods provide a basis for interpreting sparse experimental data and for independently predicting conformational and dynamic properties of glycans. Here, we summarize and analyze the issues associated with modeling carbohydrates, with a detailed discussion of four of the most recently developed carbohydrate force fields, reviewed in terms of applicability to natural glycans, carbohydrate–protein complexes and the emerging area of glycomimetic drugs. In addition, we discuss prospectives and new applications of carbohydrate modeling in drug discovery