240 research outputs found

    Samarbeid med brukere for å utvikle teknologi som skal støtte læring på arbeidsplassen : Case: Statoil Detaljhandel

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    COOPERATION WITH USERS TO DEVELOP TECHNOLOGY TO SUPPORT LEARNING AT WORK Case: Statoil Detaljhandel I was given the opportunity to join in on a project called LAP: Learning and building knowledge at work. In LAP the focus is on increasing skills on the workplace as well as supporting knowledge sharing in the organization. I joined the project as an observer, and was given the opportunity to follow different activities and happenings. As a start, we made observations at two different gas stations. To follow up, it was arranged three different focus groups where the workers got their opportunity to share their thoughts on how the future gas station should look. They were encouraged to think about technical solutions that should support learning in the everyday work. As a further step, some of the participants from the focus groups and some new participants joined a design workshop, where they were to realise the ideas from the focus groups and eventual new ideas into cardboard computers and likes. The goal of the project was to design a system to support learning at work. The participants came up with the idea of a database that should contain information on all the products that the gas stations hold, as well as descriptions on how to manage different tasks, such as changing a light bulb on a car. In my essay I have added some theory about learning, which was crucial for this project. I have also written about participatory design. The theory was used in the analysis to describe phenomena that was recognised in the actions performed. The analysis is grounded in the focus group and the design workshop, which is both described in detail. The thesis is written in Norwegian and has the title: “Samarbeid med brukere for å utvikle teknologi som skal støtte læring på arbeidsplassen. Case: Statoil Detaljhandel”

    Trends in caesarean section and instrumental deliveries in relation to Body Mass Index: a clinical survey during 1978 - 2001

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    <p>Abstract</p> <p>Background</p> <p>During the last 20 years the rate of CS has increased in Sweden as it has in many other countries. The proportion of pregnant women suffering from a high BMI has also increased rapidly during the same time period. It would therefore be of interest to study both how and if these two observations are related to each other. The aim was therefore to study trends in mode of caesarean section (CS) and instrumental deliveries among women in three BMI groups over a time span of almost 25 years with special focus on the observed body weight of pregnant women.</p> <p>Method</p> <p>The design is a retrospective cohort study using medical records of consecutively delivered women at two delivery wards in South East Sweden during the years 1978, 1986, 1992, 1997 and 2001.</p> <p>Results</p> <p>No significant time-trends were found for CS and instrumental delivery within each BMI-group for the time period studied. The proportion of women with BMI ≥ 25 delivered by means of CS or instrumental delivery increased quite dramatically from 1978 to 2001 (χ<sup>2 </sup>test for trend; p < 0.001 for both CS and instrumental deliveries). The mean birth weight in relation to BMI and year of study among women delivered by means of CS decreased, a trend that was most evident between 1997 and 2001 (F-test; p = 0.005, p = 0.004, and p = 0.003 for BMI < 20, 20-24.9, and ≥ 25, respectively).</p> <p>Conclusion</p> <p>Overweight and obese pregnant women constitute a rapidly growing proportion of the total number of CS and instrumental deliveries. Planning and allocation of health resources must be adjusted to this fact and its implications.</p

    Dagtilbudene for eldre i Fredrikstad kommune : en kartleggingsundersøkelse

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    På bakgrunn av den betydelige omorganiseringen dagsentertjenesten for eldre i Fredrikstad har vært gjenstand for de siste årene, ble det tatt initiativ fra politisk og faglig hold i kommunen til å gjøre en kartleggingsundersøkelse av tjenesten. Hovedintensjonen var å få et grunnlag for å kunne planlegge et kvalitativt godt tilbud for eldre i fremtiden. Undersøkelsen er gjennomført av ansatte og studenter ved HiØ, sykepleierutdanningen. Rapporten er basert på data fra intervju- og spørreskjemaundersøkelser hvor ansatte og brukere av dagsentrene og avdelingsledere i hjemmesykepleien er respondenter. Sentrale funn viser at brukerne er meget tilfredse med dagtilbudet. De får dekket sitt ernæringsbehov, og betydningen av å treffe andre mennesker fremheves. Undersøkelsen viser at det er behov for å skape en tjeneste som er forutsigbar, og transporten kan for enkelte oppleves som en belastning ved at den tar for lang tid. Fysisk opptrening/rehabilitering savnes av mange. Virksomhetene har store utfordringer for å kunne gi de demente og deres pårørende et godt tilbud, og det er at behov for ytterligere kartlegging av situasjonen til hjemmeboende aldersdemente. Undersøkelsen viser at små enheter med få ansatte har klare begrensninger. Det bør være ansatte med helsefaglig bakgrunn ved dagsentrene, og mye tyder på at vernepleiefaglig kompetanse er viktig

    Period prevalence and perceived side Effects of hormonal contraceptive use and the menstrual cycle in elite athletes

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    Purpose: To identify the period prevalence of hormonal contraceptive (HC) use and characterise the perceived side effects associated with the menstrual cycle and HC use. Methods: 430 elite female athletes completed a questionnaire to assess; the period prevalence of HC use, the reasons for initiation and discontinuation of HCs and the side effects experienced by HC and non-HC users. Descriptive statistics, between-group comparisons and associations between categorical variables were calculated. Results: 49.5% of athletes were currently using HCs and 69.8% had used HCs at some point. Combined oral contraceptives were most commonly used (68.1%), with 30.0% using progestin-only contraceptives (implant = 13.1%; injection = 3.7%; intrauterine system = 2.8%). Perceived negative side effects were more common with progestin-only HC use (39.1%) compared to combined HC use (17.8%; P = 0.001) and were most prevalent in implant users (53.6%; P = 0.004). HC users reported perceived positive side effects relating to the ability to predict and/or manipulate the timing, frequency and amount of menstrual bleeding. Non-HC users had a menstrual cycle length of 29± 5 d and 77.4% reported negative side effects during their menstrual cycle, primarily during days 1-2 of menstruation (81.6%). Conclusions: Approximately half of elite athletes used HCs and progestin- only contraceptive users reported greater incidences of negative side effects, especially with the implant. Due to the high inter-individual variability in reported side effects, athletes and practitioners should maintain an open dialogue to pursue the best interests of the athlete

    Bee Venom Induces Unfolded Protein Response in A172 Glioblastoma Cell Line

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    Background: Glioblastoma is a type of brain tumor with poor response to available therapies, and shows high rate of mortality. Despite remarkable advancements in our knowledge about cytogenetic and pathophysiologic features of glioblastoma, current treatment strategies are mainly based on cytotoxic drugs; however, these therapeutic approaches are facing progressive failure because of the resistant nature of glioblastomas. In the recent years, however, promising results have emerged owing to targeted therapies toward molecular pathways within cancerous cells. Unfolded Protein Response (UPR) is a remarkable signaling pathway that triggers both apoptosis and survival pathways within cells, and therefore induces UPR-related apoptotic pathways in cancer cells by ER stress inducers. Objectives: Recently, the role of Bee venom (Bv), which contains powerful bioactive peptides, in inducing UPR-related apoptosis was revealed in cancer cell lines. Nevertheless, currently there are no reports of Bv potential ability in induction of UPR apoptotic routes in glioblastoma. The aim of current study was to evaluate possible role of Bee venome in inducing of UPR pathway within A172 glioblastoma cell line. Materials and Methods: We treated the A172 glioblastoma cell line with different Bv doses, and assessed UPR-related genes expression by real-time Polymerase Chain Reaction (PCR). Results: The IC50 of Bv for the studied cell line was 28 μg/mL. Furthermore, we observed that Bv can induce UPR target genes (Grp94 and Gadd153) over-expression through a dose-dependent mechanism. Conclusions: Our results suggest the potential role of Bv as a therapeutic agent for glioblastomas. Keywords: Glioblastoma; A172 Cell Line; Unfolded Protein Response; Bee Veno

    Persistence of back pain symptoms after pregnancy and bone mineral density changes as measured by quantitative ultrasound - a two year longitudinal follow up study

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    <p>Abstract</p> <p>Background</p> <p>Previous research has shown a loss of bone mineral density (BMD) during pregnancy. This loss has been correlated to the occurrence of back pain symptoms during pregnancy. The objective of this study was to evaluate whether persistence of back pain symptoms 2 years after pregnancy could be associated with BMD changes as measured by quantitative USG of the os calcis.</p> <p>Methods</p> <p>A cohort of patients who reported significant back pain symptoms during pregnancy were surveyed for persistent back pain symptoms 24 to 28 months after the index pregnancy. Os calcis BMD was measured by quantitative ultrasound and compared with the BMD values during pregnancy.</p> <p>Results</p> <p>A cohort of 60 women who had reported significant back pain symptoms in their index pregnancy completed a 24-28 months follow-up survey and BMD reassessment. Persistence of significant back pain symptoms was seen in 24 (40%) of this cohort. These women had higher BMD loss during pregnancy compared to those without further pain (0.047 Vs 0.030 g/cm<sup>2</sup>; p = 0.03). Those that remained pain free after pregnancy appeared to have completely recovered their BMD loss in pregnancy, while those with persistent pain had lower BMD values (ΔBMD - 0.007 Vs - 0.025 g/cm<sup>2</sup>; p = 0.023) compared to their early pregnancy values.</p> <p>Conclusion</p> <p>Persistence of back pain symptoms after pregnancy could be related to an inability to recover fully from BMD loss during the index pregnancy.</p

    ‘Ripple’ Effect on Infant zBMI Trajectory of an Internet-based Weight Loss Program for Low-income Postpartum Women

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    Background: Weight loss interventions can have positive ‘ripple’ effects on untreated partners in the home, but ripple effects on infants are unknown. Objective: To examine whether a 12-month internet-based weight loss intervention for postpartum mothers had a positive ripple effect on participants’ infants. Methods: A 12-month cluster randomized, assessor-blind, clinical trial enrolling 371 postpartum women at 12 Women, Infants, Children clinics in CA. Clinics were randomized to standardWomen, Infants, Children or an internet-based weight loss intervention for mothers. Results: A total of 333 of the 371 (89.8%) mothers assented for infant participation. Infants were 5.3 ± 3.2 months; 75.9% were Hispanic and 64% were breastfeeding. Infant retention was 272/333 (82.7%) at 6 months post enrollment and 251/333 (75.3%) at 12 months post enrollment. In intent-to-treat analysis, a significant interaction between group and time was observed (p = 0.008) with the offspring of intervention mothers exhibiting lower zBMI change from study entry through 6 months (0.23 [CI, 0.03, 0.44] vs. 0.65 [0.50, 0.79] zBMI change, respectively; p = 0.001) but was not significant through 12 months (p = 0.16). Regardless of group, maternal reports at the final assessment indicated that infants (aged =17.2 ± 3.4 months) consumed sweetened beverages (0.93 ± 1.5/week), juice (2.0 ± 1.4/day), ‘junk food’ (7.8 ± 5.4/week) and fast food (2/month), and 46.7% of the infants had a TV in their bedroom. Conclusions: An internet-based weight loss program for low-income, postpartum mothers had a positive ‘ripple’ effect on the zBMI of infants in the home during the first 6 months of treatment

    Pregnancy related back pain, is it related to aerobic fitness? A longitudinal cohort study

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    <p>Abstract</p> <p>Background</p> <p>Low back pain with onset during pregnancy is common and approximately one out of three women have disabling pain. The pathogenesis of the pain condition is uncertain and there is no information on the role of physical fitness. Whether poorer physical conditioning is a cause or effect of back pain is also disputed and information from prospective studies needed.</p> <p>Methods</p> <p>A cohort of pregnant women, recruited from maternal health care centers in central Sweden, were examined regarding estimated peak oxygen uptake by cycle ergometer test in early pregnancy, reported physical activity prior to pregnancy, basic characteristics, back pain during pregnancy and back pain postpartum.</p> <p>Results</p> <p>Back pain during the current pregnancy was reported by nearly 80% of the women. At the postpartum appointment this prevalence was 40%. No association was displayed between estimated peak oxygen uptake and incidence of back pain during and after pregnancy, adjusted for physical activity, back pain before present pregnancy, previous deliveries, age and weight. A significant inverse association was found between estimated peak oxygen uptake and back pain intensity during pregnancy and a direct association post partum, in a fully adjusted multiple linear regression analysis.</p> <p>Conclusions</p> <p>Estimated peak oxygen uptake and reported physical activity in early pregnancy displayed no influence on the onset of subsequent back pain during or after pregnancy, where the time sequence support the hypothesis that poorer physical deconditioning is not a cause but a consequence of the back pain condition. The mechanism for the attenuating effect of increased oxygen uptake on back pain intensity is uncertain.</p
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