116 research outputs found
Qu’apporte l’étude des town meetings à la quête d’une démocratie plus participative et délibérative?
Comme annoncé dans l’introduction, ce numéro spécial de Participations se clôt sur un entretien collectif, mené par Paula Cossart et Andrea Felicetti, rassemblant certains des plus éminents représentants de la recherche sur les town meetings de Nouvelle-Angleterre. Trois ensembles de questions ont été soumis à chaque interviewé, qui y a répondu individuellement par écrit. Hors corrections mineures, le texte des réponses n’a pas été modifié ; mais il a parfois été segmenté de manière à rendre la lecture plus fluide, et à mettre en évidence
les interactions entre les différentes perspectives présentes dans ces lignes. La version finale de ce texte a été éditée et approuvée par les chercheurs interrogés
The Vehicle, Fall 2009
Table of Contents
Poetry
AliveRashelle McNairpage 3
Train of ThoughtsJeanette Saribekianpage 4
Biding the TideMarlee Lutzpage 5
Rotten HarvestJessyca Revillapage 15
Nostalgia ODJustine Fittonpage 16
Beyond WordsAshley Wrightpage 26
Don\u27tMelinda Knightpage 27
Happy HourStephen Garciapage 35
UntitledDaniel Paquinpage 37
Vibrant SensationsAshton Tembypage 38
Scarecrow Sally on a Saturday NightDaniel Davispage 45
The FarmAshley Wrightpage 49
Anything ButJustine Fittonpage 51
CrashDanielle Shirtinopage 53
Weathering SatisfactionRashelle McNairpage 54
SeminarDaniel Davispage 71
Nature\u27s Mood SwingsJeanette Saribekianpage 72
The PerformanceMelinda Knightpage 68
AmaterasuMarlee Lutzpage 82
Prose
AirLauren Davidsonpage 6
The Twang of OrangesJ.T. Dawsonpage 18
ListenStephani Pescitellipage 29
The Rise and Fall of NickNickolas Alexanderpage 30
LossSimyona Deanovapage 39
Like DiamondsMark Rheaumepage 42
Moral FixationBryan Rolfsenpage 47
Reflections in College AlgebraNicole Reichertpage 52
LeashDaniel Paquinpage 56
I Lost My KeysJustine Fittonpage 75
A Third Grade EssayMark Rheaumepage 69
Be Careful, They BiteDaniel Davispage 84
Art
Limb BurgAlycia Rockeycover
AvesSamantha Flowerspage 14
Life-LuminescenceStephani Pescitellipage 25
MonopolyMegan Mathypage 28
Carousel NostalgiaAlycia Rockeypage 36
ShoesSarah Olsonpage 41
Waimea BayJarrod Taylorpage 50
Peacock Plumage Alycia Rockeypage 55
Building a HouseStephani Pescitellipage 70
ShellMegan Mathypage 74
From the VacationSamantha Flowerspage 73
Chicago CanopyAlycia Rockeypage 83
Features
Editor\u27s NoteLindsey Durbinpage 1
LazarusDr. David Radavichpage 2
James K. Johnson Creative Writing Awardpage 88
Winning Entries (Poetry)Matthew J. Schumakepage 89
Winning Entry (Nonfiction)Jennifer O\u27Neilpage 92
Interview, 2009 Chapbook WinnerDaniel Davispage 95
Contributorspage 99https://thekeep.eiu.edu/vehicle/1090/thumbnail.jp
The Vehicle, Fall 2009
Table of Contents
Poetry
AliveRashelle McNairpage 3
Train of ThoughtsJeanette Saribekianpage 4
Biding the TideMarlee Lutzpage 5
Rotten HarvestJessyca Revillapage 15
Nostalgia ODJustine Fittonpage 16
Beyond WordsAshley Wrightpage 26
Don\u27tMelinda Knightpage 27
Happy HourStephen Garciapage 35
UntitledDaniel Paquinpage 37
Vibrant SensationsAshton Tembypage 38
Scarecrow Sally on a Saturday NightDaniel Davispage 45
The FarmAshley Wrightpage 49
Anything ButJustine Fittonpage 51
CrashDanielle Shirtinopage 53
Weathering SatisfactionRashelle McNairpage 54
SeminarDaniel Davispage 71
Nature\u27s Mood SwingsJeanette Saribekianpage 72
The PerformanceMelinda Knightpage 68
AmaterasuMarlee Lutzpage 82
Prose
AirLauren Davidsonpage 6
The Twang of OrangesJ.T. Dawsonpage 18
ListenStephani Pescitellipage 29
The Rise and Fall of NickNickolas Alexanderpage 30
LossSimyona Deanovapage 39
Like DiamondsMark Rheaumepage 42
Moral FixationBryan Rolfsenpage 47
Reflections in College AlgebraNicole Reichertpage 52
LeashDaniel Paquinpage 56
I Lost My KeysJustine Fittonpage 75
A Third Grade EssayMark Rheaumepage 69
Be Careful, They BiteDaniel Davispage 84
Art
Limb BurgAlycia Rockeycover
AvesSamantha Flowerspage 14
Life-LuminescenceStephani Pescitellipage 25
MonopolyMegan Mathypage 28
Carousel NostalgiaAlycia Rockeypage 36
ShoesSarah Olsonpage 41
Waimea BayJarrod Taylorpage 50
Peacock Plumage Alycia Rockeypage 55
Building a HouseStephani Pescitellipage 70
ShellMegan Mathypage 74
From the VacationSamantha Flowerspage 73
Chicago CanopyAlycia Rockeypage 83
Features
Editor\u27s NoteLindsey Durbinpage 1
LazarusDr. David Radavichpage 2
James K. Johnson Creative Writing Awardpage 88
Winning Entries (Poetry)Matthew J. Schumakepage 89
Winning Entry (Nonfiction)Jennifer O\u27Neilpage 92
Interview, 2009 Chapbook WinnerDaniel Davispage 95
Contributorspage 99https://thekeep.eiu.edu/vehicle/1090/thumbnail.jp
The PHENIX Experiment at RHIC
The physics emphases of the PHENIX collaboration and the design and current
status of the PHENIX detector are discussed. The plan of the collaboration for
making the most effective use of the available luminosity in the first years of
RHIC operation is also presented.Comment: 5 pages, 1 figure. Further details of the PHENIX physics program
available at http://www.rhic.bnl.gov/phenix
Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome
Loss of function in the Scn1a gene leads to a severe epileptic encephalopathy called Dravet syndrome (DS). Reduced excitability in cortical inhibitory neurons is thought to be the major cause of DS seizures. Here, in contrast, we show enhanced excitability in thalamic inhibitory neurons that promotes the non-convulsive seizures that are a prominent yet poorly understood feature of DS. In a mouse model of DS with a loss of function in Scn1a, reticular thalamic cells exhibited abnormally long bursts of firing caused by the downregulation of calcium-activated potassium SK channels. Our study supports a mechanism in which loss of SK activity causes the reticular thalamic neurons to become hyperexcitable and promote non-convulsive seizures in DS. We propose that reduced excitability of inhibitory neurons is not global in DS and that non-GABAergic mechanisms such as SK channels may be important targets for treatment.In a mouse model of Dravet syndrome (DS) resulting from voltage-gated sodium channel deficiency, Ritter-Makinson et al. find that inhibitory neurons of the reticular thalamic nucleus are paradoxically hyperexcitable due to compensatory reductions in a potassium SK current. Boosting this SK current treats non-convulsive seizures in DS mice
Baryons: What, When and Where?
We review the current state of empirical knowledge of the total budget of
baryonic matter in the Universe as observed since the epoch of reionization.
Our summary examines on three milestone redshifts since the reionization of H
in the IGM, z = 3, 1, and 0, with emphasis on the endpoints. We review the
observational techniques used to discover and characterize the phases of
baryons. In the spirit of the meeting, the level is aimed at a diverse and
non-expert audience and additional attention is given to describe how space
missions expected to launch within the next decade will impact this scientific
field.Comment: Proceedings Review for "Astrophysics in the Next Decade: JWST and
Concurrent Facilities", ed. X. Tielens, 38 pages, 10 color figures. Revised
to address comments from the communit
Novel genetic loci associated with hippocampal volume
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness
Age at first birth in women is genetically associated with increased risk of schizophrenia
Prof. Paunio on PGC:n jäsenPrevious studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic association between schizophrenia and age at first birth in women (AFB). Here, we use independent data from the UK Biobank (N = 38,892) to replicate the finding of an association between predicted genetic risk of schizophrenia and AFB in women, and to estimate the genetic correlation between schizophrenia and AFB in women stratified into younger and older groups. We find evidence for an association between predicted genetic risk of schizophrenia and AFB in women (P-value = 1.12E-05), and we show genetic heterogeneity between younger and older AFB groups (P-value = 3.45E-03). The genetic correlation between schizophrenia and AFB in the younger AFB group is -0.16 (SE = 0.04) while that between schizophrenia and AFB in the older AFB group is 0.14 (SE = 0.08). Our results suggest that early, and perhaps also late, age at first birth in women is associated with increased genetic risk for schizophrenia in the UK Biobank sample. These findings contribute new insights into factors contributing to the complex bio-social risk architecture underpinning the association between parental age and offspring mental health.Peer reviewe
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