1,129 research outputs found

    Rare Kaon Decays in the 1/Nc1/N_c-Expansion

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    We study the unknown coupling constants that appear at order p4p^4 in the Chiral Perturbation Theory analysis of Kπγπl+lK \to \pi \gamma^* \to \pi l^+ l^-, K+π+γγK^{+-} \to \pi^{+-} \gamma \gamma and KππγK \to \pi \pi \gamma decays. To that end, we compute the chiral realization of the ΔS=1\Delta S \, = \, 1 Hamiltonian in the framework of the 1/Nc1/N_c-expansion of the low-energy action. The phenomenological implications are also discussed.Comment: 18 pages, LaTeX, CPT-92/P.279

    hypomyelination and congenital cataract neuroimaging features of a novel inherited white matter disorder

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    BACKGROUND AND PURPOSE: Hypomyelination and congenital cataract (HCC) is an autosomal recessive white matter disease caused by deficiency of hyccin, a membrane protein implicated in both central and peripheral myelination. We aimed to describe the neuroimaging features of this novel entity. MATERIALS AND METHODS: A systematic analysis of patients with unclassified leukoencephalopathies admitted to our institutions revealed 10 children with congenital cataract, slowly progressive neurologic impairment, and diffuse white matter abnormalities on neuroimaging. Psychomotor developmental delay was evident after the first year of life. Peripheral neuropathy was demonstrated by neurophysiologic studies in 9 children. The available neuroimaging studies were retrospectively reviewed. RESULTS: In all patients, neuroimaging revealed diffuse involvement of the supratentorial white matter associated with preservation of both cortical and deep gray matter structures. Supratentorial white matter hypomyelination was detected in all patients; 7 patients also had evidence of variably extensive areas of increased white matter water content. Deep cerebellar white matter hypomyelination was found in 6 patients. Older patients had evidence of white matter bulk loss and gliosis. Proton MR spectroscopy showed variable findings, depending on the stage of the disease. Sural nerve biopsy revealed hypomyelinated nerve fibers. Mutations in the DRCTNNB1A gene on chromosome 7p15.3, causing complete or severe deficiency of hyccin, were demonstrated in all patients. CONCLUSIONS: HCC is characterized by a combined pattern of primary myelin deficiency and secondary neurodegenerative changes. In the proper clinical setting, recognition of suggestive neuroimaging findings should prompt appropriate genetic investigations

    Ideal Spin Filters: Theoretical Study of Electron Transmission Through Ordered and Disordered Interfaces Between Ferromagnetic Metals and Semiconductors

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    It is predicted that certain atomically ordered interfaces between some ferromagnetic metals (F) and semiconductors (S) should act as ideal spin filters that transmit electrons only from the majority spin bands or only from the minority spin bands of the F to the S at the Fermi energy, even for F with both majority and minority bands at the Fermi level. Criteria for determining which combinations of F, S and interface should be ideal spin filters are formulated. The criteria depend only on the bulk band structures of the S and F and on the translational symmetries of the S, F and interface. Several examples of systems that meet these criteria to a high degree of precision are identified. Disordered interfaces between F and S are also studied and it is found that intermixing between the S and F can result in interfaces with spin anti-filtering properties, the transmitted electrons being much less spin polarized than those in the ferromagnetic metal at the Fermi energy. A patent application based on this work has been commenced by Simon Fraser University.Comment: RevTeX, 12 pages, 5 figure

    Prey naiveté to invasive lionfish Pterois volitans on Caribbean coral reefs

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    Native prey can be particularly vulnerable to consumption by exotic predators. Prey naiveté, the failure to recognize a novel predator due to lack of recent co-evolutionary history, likely facilitates the disproportionate impact that some exotic predators exert on prey populations. Lionfish Pterois volitans, exotic predators from the Pacific, have invaded coral reefs and other coastal habitats along the western Atlantic. Prey naiveté towards novel lionfish was tested in field experiments and with observations using closest approach distance as the anti-predator response. We quantified the distance of prey fishes to exotic lionfish in both the Atlantic and Pacific (invasive and native ranges of lionfish) as well as to native predators in the Atlantic. In the Atlantic, experiments indicated that Haemulon plumierii, prey of lionfish, generally display a closer approach distance to exotic than to native predators, and field observations of free-ranging fish revealed that at least 5 other species of small fishes (Halichoeres bivitattus, Halichoeres garnoti, Scarus taeniopterus, Stegastes leucostictus and Thalassoma bifasciatum) also might exhibit limited predatoravoidance behaviour towards invasive lionfish. We also found that 3 families of small fish (Labridae, Pomacentridae and Scaridae) maintained greater distances from lionfish in the Pacific compared with the Atlantic in both experimental and field observations. These results suggest prey naiveté to exotic lionfish by at least 8 species of fish (Abudefduf saxatilis, H. plumierii, H. bivitattus, H. garnoti, S. taeniopterus, Sparisoma aurofrenatum, S. leucostictus and T. bifasciatum) in the Atlantic, which could be contributing to the rapid expansion of this invasive species by enhancing its fitness and reproductive output through high predation efficiency

    State sampling dependence of the Hopfield network inference

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    The fully connected Hopfield network is inferred based on observed magnetizations and pairwise correlations. We present the system in the glassy phase with low temperature and high memory load. We find that the inference error is very sensitive to the form of state sampling. When a single state is sampled to compute magnetizations and correlations, the inference error is almost indistinguishable irrespective of the sampled state. However, the error can be greatly reduced if the data is collected with state transitions. Our result holds for different disorder samples and accounts for the previously observed large fluctuations of inference error at low temperatures.Comment: 4 pages, 1 figure, further discussions added and relevant references adde

    Pore-scale Modeling of Viscous Flow and Induced Forces in Dense Sphere Packings

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    We propose a method for effectively upscaling incompressible viscous flow in large random polydispersed sphere packings: the emphasis of this method is on the determination of the forces applied on the solid particles by the fluid. Pore bodies and their connections are defined locally through a regular Delaunay triangulation of the packings. Viscous flow equations are upscaled at the pore level, and approximated with a finite volume numerical scheme. We compare numerical simulations of the proposed method to detailed finite element (FEM) simulations of the Stokes equations for assemblies of 8 to 200 spheres. A good agreement is found both in terms of forces exerted on the solid particles and effective permeability coefficients

    SATSal: A Multi-Level Self-Attention Based Architecture for Visual Saliency Prediction

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    Human visual Attention modelling is a persistent interdisciplinary research challenge, gaining new interest in recent years mainly due to the latest developments in deep learning. That is particularly evident in saliency benchmarks. Novel deep learning-based visual saliency models show promising results in capturing high-level (top-down) human visual attention processes. Therefore, they strongly differ from the earlier approaches, mainly characterised by low-level (bottom-up) visual features. These developments account for innate human selectivity mechanisms that are reliant on both high- and low-level factors. Moreover, the two factors interact with each other. Motivated by the importance of these interactions, in this project, we tackle visual saliency modelling holistically, examining if we could consider both high- and low-level features that govern human attention. Specifically, we propose a novel method SAtSal (Self-Attention Saliency). SAtSal leverages both high and low-level features using a multilevel merging of skip connections during the decoding stage. Consequently, we incorporate convolutional self-attention modules on skip connection from the encoder to the decoder network to properly integrate the valuable signals from multilevel spatial features. Thus, the self-attention modules learn to filter out the latent representation of the salient regions from the other irrelevant information in an embedded and joint manner with the main encoder-decoder model backbone. Finally, we evaluate SAtSal against various existing solutions to validate our approach, using the well-known standard saliency benchmark MIT300. To further examine SAtSal's robustness on other image types, we also evaluate it on the Le-Meur saliency painting benchmark

    The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria

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    Infection with Plasmodium vivax results in strong activation of monocytes, which are important components of both the systemic inflammatory response and parasite control. The overall goal of this study was to define the role of monocytes during P. vivax malaria. Here, we demonstrate that P. vivax-infected patients display significant increase in circulating monocytes, which were defined as CD14(+)CD16- (classical), CD14(+)CD16(+) (inflammatory), and CD14loCD16(+) (patrolling) cells. While the classical and inflammatory monocytes were found to be the primary source of pro-inflammatory cytokines, the CD16(+) cells, in particular the CD14(+)CD16(+) monocytes, expressed the highest levels of activation markers, which included chemokine receptors and adhesion molecules. Morphologically, CD14(+) were distinguished from CD14lo monocytes by displaying larger and more active mitochondria. CD14(+)CD16(+) monocytes were more efficient in phagocytizing P. vivax-infected reticulocytes, which induced them to produce high levels of intracellular TNF-alpha and reactive oxygen species. Importantly, antibodies specific for ICAM-1, PECAM-1 or LFA-1 efficiently blocked the phagocytosis of infected reticulocytes by monocytes. Hence, our results provide key information on the mechanism by which CD14(+)CD16(+) cells control parasite burden, supporting the hypothesis that they play a role in resistance to P. vivax infection

    Automorphic Equivalence within Gapped Phases of Quantum Lattice Systems

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    Gapped ground states of quantum spin systems have been referred to in the physics literature as being `in the same phase' if there exists a family of Hamiltonians H(s), with finite range interactions depending continuously on s[0,1]s \in [0,1], such that for each ss, H(s) has a non-vanishing gap above its ground state and with the two initial states being the ground states of H(0) and H(1), respectively. In this work, we give precise conditions under which any two gapped ground states of a given quantum spin system that 'belong to the same phase' are automorphically equivalent and show that this equivalence can be implemented as a flow generated by an ss-dependent interaction which decays faster than any power law (in fact, almost exponentially). The flow is constructed using Hastings' 'quasi-adiabatic evolution' technique, of which we give a proof extended to infinite-dimensional Hilbert spaces. In addition, we derive a general result about the locality properties of the effect of perturbations of the dynamics for quantum systems with a quasi-local structure and prove that the flow, which we call the {\em spectral flow}, connecting the gapped ground states in the same phase, satisfies a Lieb-Robinson bound. As a result, we obtain that, in the thermodynamic limit, the spectral flow converges to a co-cycle of automorphisms of the algebra of quasi-local observables of the infinite spin system. This proves that the ground state phase structure is preserved along the curve of models H(s),0s1H(s), 0\leq s\leq 1.Comment: Updated acknowledgments and new email address of S
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