Examining Links between Social Anxiety and Relational Aggression in Adolescence: The Influence of Rumination and Anger

Social anxiety is linked to more covert forms of aggressive behavior, particularly reactive and relational aggression in early adolescent and young adult samples. Adolescents with social anxiety and those who engage in reactive relational aggression are also more likely to have difficulties regulating emotions (e.g., anger) and show maladaptive cognitive coping styles (e.g., rumination). The goal of the present study was to assess the relationship between social anxiety and reactive relational aggression in adolescents (14-17 years), combining the form and function of aggression, and to examine trait anger and anger rumination as underlying factors that may explain the relationship between social anxiety and reactive relational aggression. The current study hypothesized that adolescents with social anxiety would engage in reactive relational aggression through the use of anger rumination, and this relationship would only be present in adolescents with higher levels of trait anger. High school adolescents in grades 9 to 12 (N=105; Mage = 15.43; 61% female) were recruited through their local school and community to complete a 30-minute, battery of questionnaires examining social anxiety, trait anger, anger rumination, and reactive relational aggression. Adolescents completed questionnaires anonymously via an online survey platform, Qualtrics, and were subsequently compensated for their time. Results supported study hypotheses. Simple regression analyses found that social anxiety was positively related to trait anger, anger rumination and reactive relational aggression. Trait anger and anger rumination were also positively correlated with reactive relational aggression. A conditional process analysis was conducted to test the major study hypothesis. Adolescents with social anxiety were more likely to engage in reactive relational aggression if they ruminated about experiences that created anger, and this relationship was present in adolescents with higher levels of trait anger. Gender differences were also explored. Higher rates of social anxiety and anger rumination were found in females. No other gender differences were found. Overall, socially anxious adolescents showed a greater tendency to engage in reactive relational aggression adding to the current literature. Difficulties regulating negative emotions, like anger, and ineffective cognitive coping strategies, such as anger rumination, were precipitating factors that likely maintained socially anxious and aggressive behaviors

Recency of Faulting and Subsurface Architecture of the San Diego Bay Pull-Apart Basin, California, USA

In Southern California, plate boundary motion between the North American and Pacific plates is distributed across several sub-parallel fault systems. The offshore faults of the California Continental Borderland (CCB) are thought to accommodate ∼10–15% of the total plate boundary motion, but the exact distribution of slip and the mechanics of slip partitioning remain uncertain. The Newport-Inglewood-Rose Canyon fault is the easternmost fault within the CCB whose southern segment splays out into a complex network of faults beneath San Diego Bay. A pull-apart basin model between the Rose Canyon and the offshore Descanso fault has been used to explain prominent fault orientations and subsidence beneath San Diego Bay; however, this model does not account for faults in the southern portion of the bay or faulting east of the bay. To investigate the characteristics of faulting and stratigraphic architecture beneath San Diego Bay, we combined a suite of reprocessed legacy airgun multi-channel seismic profiles and high-resolution Chirp data, with age and lithology controls from geotechnical boreholes and shallow sub-surface vibracores. This combined dataset is used to create gridded horizon surfaces, fault maps, and perform a kinematic fault analysis. The structure beneath San Diego Bay is dominated by down-to-the-east motion on normal faults that can be separated into two distinct groups. The strikes of these two fault groups can be explained with a double pull-apart basin model for San Diego Bay. In our conceptual model, the western portion of San Diego Bay is controlled by a right-step between the Rose Canyon and Descanso faults, which matches both observations and predictions from laboratory models. The eastern portion of San Diego Bay appears to be controlled by an inferred step-over between the Rose Canyon and San Miguel-Vallecitos faults and displays distinct fault strike orientations, which kinematic analysis indicates should have a significant component of strike-slip partitioning that is not detectable in the seismic data. The potential of a Rose Canyon-San Miguel-Vallecitos fault connection would effectively cut the stepover distance in half and have important implications for the seismic hazard of the San Diego-Tijuana metropolitan area (population ∼3 million people)

STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+T cell dysregulation and accumulation

The association between cancer and autoimmune disease is unexplained, exemplified by T cell large granular lymphocytic leukemia (T-LGL) where gain-of-function (GOF) somatic STAT3 mutations correlate with co -exist-ing autoimmunity. To investigate whether these mutations are the cause or consequence of CD8+ T cell clonal expansions and autoimmunity, we analyzed patients and mice with germline STAT3 GOF mutations. STAT3 GOF mutations drove the accumulation of effector CD8+ T cell clones highly expressing NKG2D, the receptor for stress-induced MHC-class-I-related molecules. This subset also expressed genes for granzymes, perforin, interferon-y, and Ccl5/Rantes and required NKG2D and the IL-15/IL-2 receptor IL2RB for maximal accumula-tion. Leukocyte-restricted STAT3 GOF was sufficient and CD8+ T cells were essential for lethal pathology in mice. These results demonstrate that STAT3 GOF mutations cause effector CD8+ T cell oligoclonal accumu-lation and that these rogue cells contribute to autoimmune pathology, supporting the hypothesis that somatic mutations in leukemia/lymphoma driver genes contribute to autoimmune disease.Peer reviewe

An ultra-wide bandwidth (704 to 4 032 MHz) receiver for the Parkes radio telescope

We describe an ultra-wide-bandwidth, low-frequency receiver recently installed on the Parkes radio telescope. The receiver system provides continuous frequency coverage from 704 to 4032 MHz. For much of the band ( ${∼}60$ ), the system temperature is approximately 22 K and the receiver system remains in a linear regime even in the presence of strong mobile phone transmissions. We discuss the scientific and technical aspects of the new receiver, including its astronomical objectives, as well as the feed, receiver, digitiser, and signal processor design. We describe the pipeline routines that form the archive-ready data products and how those data files can be accessed from the archives. The system performance is quantified, including the system noise and linearity, beam shape, antenna efficiency, polarisation calibration, and timing stability

Infection after medical abortion: a review of the literature.

Medical abortion regimens have become widely used, but the frequency of infection after medical abortion is not well documented. This systematic review provides data on infectious complications after medical abortion. We searched Medline for articles written before July 2003 to determine the frequency of infection after medical abortion up to 26 weeks of gestation. We reviewed all articles and extracted data on the frequency of infection from 65 studies. The frequency of diagnosed and/or treated infection after medical abortion was very low (0.92%, N = 46,421) and varied among regimens. Results of this review confirm that, with respect to infectious complications, medical abortion is a safe and effective option for first- and second-trimester pregnancy termination. After accounting for regional variations in diagnosis, there is little difference in frequency of infection among the regimens reviewed. Future studies should report clear diagnosis and treatment standards for infection so that more precise information becomes available