1,081 research outputs found

    Transformational Leadership Assessment of Nurse Managers and Assistant Nurse Managers

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    Transformational Leadership behaviors are essential to build and sustain a healthy work environment in healthcare. Nurse Managers who possess transformational leadership behaviors lead nursing teams with a higher degree of engagement, work satisfaction, and retention. The purpose of this project was to perform an assessment of transformational leadership characteristics among nurse managers and assistant nurse managers, develop an educational program to teach transformational leadership behaviors, and incorporate a transformational leadership assessment into the orientation onboarding process of new nurse managers and assistant nurse managers. The Full Range Leadership Model (FRLM) asserts leaders should use multiple leadership characteristics or behaviors to effectively lead teams. A voluntary convenience sample of 21 Registered Nurses who held a nurse manger or assistant nurse manager role participated in this project. The tool used to assess leadership characteristics was the Multifactor Leadership Questionnaire-5X (MLQ-5X). Of the participants who attended the two presentations which were intended to review the MLQ-5X leadership characteristic assessment results, no one indicated the ability to discuss the importance of transformational leadership behaviors prior to the education, while 65% of the attendees indicated the ability to discuss the importance of transformational leadership behaviors following the education. In addition, 100% of the Nurse Manager and Assistant Nurse Manager participants who attended the education indicated the MLQ-5X leadership assessment tool should be administered to all newly hired nurse managers and assistant nurse managers as part an onboarding educational plan. Of the participants attending the two presentations to share transformational leadership behaviors to retain registered nursing staff, 82% indicated the presentation was “absolutely” beneficial. No one indicated the education was not beneficial to their individual leadership education

    Signalling pathways and mechanistic cues highlighted by transcriptomic analysis of primordial, primary, and secondary ovarian follicles in domestic cat

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    In vitro growth (IVG) of dormant primordial ovarian follicles aims to produce mature competent oocytes for assisted reproduction. Success is dependent on optimal in vitro conditions complemented with an understanding of oocyte and ovarian follicle development in vivo. Complete IVG has not been achieved in any other mammalian species besides mice. Furthermore, ovarian folliculogenesis remains sparsely understood overall. Here, gene expression patterns were characterised by RNA-sequencing in primordial (PrF), primary (PF), and secondary (SF) ovarian follicles from Felis catus (domestic cat) ovaries. Two major transitions were investigated: PrF-PF and PF-SF. Transcriptional analysis revealed a higher proportion in gene expression changes during the PrF-PF transition. Key influencing factors during this transition included the interaction between the extracellular matrix (ECM) and matrix metalloproteinase (MMPs) along with nuclear components such as, histone HIST1H1T (H1.6). Conserved signalling factors and expression patterns previously described during mammalian ovarian folliculogenesis were observed. Species-specific features during domestic cat ovarian folliculogenesis were also found. The signalling pathway terms "PI3K-Akt", "transforming growth factor-β receptor", "ErbB", and "HIF-1" from the functional annotation analysis were studied. Some results highlighted mechanistic cues potentially involved in PrF development in the domestic cat. Overall, this study provides an insight into regulatory factors and pathways during preantral ovarian folliculogenesis in domestic cat.Peer reviewe

    Signalling pathways and mechanistic cues highlighted by transcriptomic analysis of primordial, primary, and secondary ovarian follicles in domestic cat

    Get PDF
    In vitro growth (IVG) of dormant primordial ovarian follicles aims to produce mature competent oocytes for assisted reproduction. Success is dependent on optimal in vitro conditions complemented with an understanding of oocyte and ovarian follicle development in vivo. Complete IVG has not been achieved in any other mammalian species besides mice. Furthermore, ovarian folliculogenesis remains sparsely understood overall. Here, gene expression patterns were characterised by RNA-sequencing in primordial (PrF), primary (PF), and secondary (SF) ovarian follicles from Felis catus (domestic cat) ovaries. Two major transitions were investigated: PrF-PF and PF-SF. Transcriptional analysis revealed a higher proportion in gene expression changes during the PrF-PF transition. Key influencing factors during this transition included the interaction between the extracellular matrix (ECM) and matrix metalloproteinase (MMPs) along with nuclear components such as, histone HIST1H1T (H1.6). Conserved signalling factors and expression patterns previously described during mammalian ovarian folliculogenesis were observed. Species-specific features during domestic cat ovarian folliculogenesis were also found. The signalling pathway terms "PI3K-Akt", "transforming growth factor-beta receptor", "ErbB", and "HIF-1" from the functional annotation analysis were studied. Some results highlighted mechanistic cues potentially involved in PrF development in the domestic cat. Overall, this study provides an insight into regulatory factors and pathways during preantral ovarian folliculogenesis in domestic cat

    Adolescentes en Chile: propuesta de armonizaciĂłn de su condiciĂłn de relativamente incapaces con el reconocimiento de su autonomĂ­a progresiva

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    From the constitutional need to integrate the concept of progressive autonomy of the minor in the internal regulations, the authors propose the plausibility, for the Chilean case, of understanding the aforementioned principle compatible with the system of protection based on disability and invalidation, provided that each one is assigned a separate field of application: the first for extra-economic acts and interests, the second for property businesses. This interpretative proposal allows the preservation of the advantages of the private law´s incapacitation/invalidation system applicable to the acts carried out by a relatively incapable minor-adult, on one hand, with the necessary recognition of the decisions of the progressively autonomous adolescent in the personal sphere, on the other.Frente al requerimiento constitucional de integrar el concepto de autonomía progresiva del menor de edad en la normativa civil interna, los autores plantean la plausibilidad, para el caso chileno, de entender compatible ese principio con el sistema de protección basado en la incapacidad y la invalidación, a condición de que se asigne a cada uno un campo aplicativo separado: el primero para los actos e intereses extrapatrimoniales, el segundo para los negocios patrimoniales. Esta propuesta interpretativa permitiría conservar las ventajas del sistema civil de incapacitación invalidación aplicable a los actos realizados por un menor adulto relativamente incapaz, por un lado, con el necesario reconocimiento de las decisiones del adolescente progresivamente autónomo en el ámbito personal, por otro

    Racial Categories in Medical Practice: How Useful Are They?

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    Is it good medical practice for physicians to "eyeball" a patient's race when assessing their medical status or even to ask them to identify their race

    "Stirred, Not Shaken: An Assessment Remixology"

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    Curatorial note from Digital Pedagogy in the Humanities: Delagrange et al. suggest a clear, implementable procedure for navigating the complex process of [assessment](/keyword/assessment) for remix assignments. In the tab “Evolving Rubric,” Delagrange outlines a set of steps for instructors and students to collaboratively create a grading rubric. In addition, she provides examples of student work that can help sharpen students’ analysis of the criteria included in the assessment. Part of the larger 2013 collection Digital Writing Assessment and Evaluation, “Stirred, Not Shaken” also contributes a set of sample assignments and evaluation processes for remix projects in writing courses and describes additional expository and reflective writing assignments that expand students’ concepts of remix practices and circulation. In addition to these assignments, authors put forward a narrative describing the implementation of fair use and an assessment of the role of remix in larger institutional learning outcomes

    The potential of painting: unlocking Disenfranchised Grief for people living with dementia

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    As part of the “Creative Well” programme at Betsi Cadwaladr University Health Board (BCUHN) North Wales, artist/researchers Megan Wyatt and Susan Liggett qualitatively investigated how painting can access a means of communication for people living with Dementia. In a workshop setting within a gallery environment at Ruthin Crafts Centre, participants living with dementia were facilitated on a one to one basis the opportunity to paint alongside the artist/researchers. The participants were from a wellestablished art group called “Lost in Art” that is managed by Denbighshire Arts Service. During the workshops, a number of experiences were articulated. These included experiences of illness, crisis and loss. They were captured through observations, interviews, visual art and video to contribute to new understandings and models of engagement through art for people living with dementia and their carers. Focusing on theory and practice in arts based research and the social sciences, this paper investigates the potential of painting to unlock experiences such as disenfranchised grief for people living with dementia. The conclusions do not measure how and if participants felt disenfranchised grief but rather provide an alternative to augment the body of knowledge surrounding how people living with dementia can communicate feelings of disenfranchised grief through painting. Objective: In this presentation I aim to outline the main findings from the above paper that is to be published in an academic journal later in the year on Illness Crisis and Loss published by Sage

    Sialylation of campylobacter jejuni lipo-oligosaccharides: impact on phagocytosis and cytokine production in mice

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    <p>Background: Guillain-Barré syndrome (GBS) is a post-infectious polyradiculoneuropathy, frequently associated with antecedent Campylobacter jejuni (C. jejuni) infection. The presence of sialic acid on C. jejuni lipo-oligosaccharide (LOS) is considered a risk factor for development of GBS as it crucially determines the structural homology between LOS and gangliosides, explaining the induction of cross-reactive neurotoxic antibodies. Sialylated C. jejuni are recognised by TLR4 and sialoadhesin; however, the functional implications of these interactions in vivo are unknown.</p> <p>Methodology/Principal Findings: In this study we investigated the effects of bacterial sialylation on phagocytosis and cytokine secretion by mouse myeloid cells in vitro and in vivo. Using fluorescently labelled GM1a/GD1a ganglioside-mimicking C. jejuni strains and corresponding (Cst-II-mutant) control strains lacking sialic acid, we show that sialylated C. jejuni was more efficiently phagocytosed in vitro by BM-MΦ, but not by BM-DC. In addition, LOS sialylation increased the production of IL-10, IL-6 and IFN-β by both BM-MΦ and BM-DC. Subsequent in vivo experiments revealed that sialylation augmented the deposition of fluorescent bacteria in splenic DC, but not macrophages. In addition, sialylation significantly amplified the production of type I interferons, which was independent of pDC.</p> <p>Conclusions/Significance: These results identify novel immune stimulatory effects of C. jejuni sialylation, which may be important in inducing cross-reactive humoral responses that cause GBS</p&gt
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