707 research outputs found
Reconstruction of photon statistics using low performance photon counters
The output of a photodetector consists of a current pulse whose charge has
the statistical distribution of the actual photon numbers convolved with a
Bernoulli distribution. Photodetectors are characterized by a nonunit quantum
efficiency, i.e. not all the photons lead to a charge, and by a finite
resolution, i.e. a different number of detected photons leads to a
discriminable values of the charge only up to a maximum value. We present a
detailed comparison, based on Monte Carlo simulated experiments and real data,
among the performances of detectors with different upper limits of counting
capability. In our scheme the inversion of Bernoulli convolution is performed
by maximum-likelihood methods assisted by measurements taken at different
quantum efficiencies. We show that detectors that are only able to discriminate
between zero, one and more than one detected photons are generally enough to
provide a reliable reconstruction of the photon statistics for single-peaked
distributions, while detectors with higher resolution limits do not lead to
further improvements. In addition, we demonstrate that, for semiclassical
states, even on/off detectors are enough to provide a good reconstruction.
Finally, we show that a reliable reconstruction of multi-peaked distributions
requires either higher quantum efficiency or better capability in
discriminating high number of detected photons.Comment: 8 pages, 3 figure
Sensibility in the novels of James Fenimore Cooper
In the eighteenth and nineteenth centuries, the term "sensibility" denoted "quickness and acuteness of apprehension or feeling; sensitiveness" and the "capacity for refined emotion; delicate sensitiveness of taste; and readiness to feel compassion for suffering, and to be moved by the pathetic in literature or art" (OED). Although sensibility is not historically synonymous with "sentimentality," excessive sensibility can and often does degenerate into sentimentality. In American literature such exaggerated sensibility is a pervasive ingredient in the sentimental novel
Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research.
BackgroundThe National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use. The challenge is to prioritize chemicals for biomonitoring that may present health risk concerns.ObjectivesOur aim was to prioritize chemicals that may elicit child health effects of interest to ECHO but that have not been biomonitored nationwide and to identify gaps needing additional research.MethodsWe searched databases and the literature for chemicals in environmental media and in consumer products that were potentially toxic. We selected chemicals that were not measured in the National Health and Nutrition Examination Survey. From over 700 chemicals, we chose 155 chemicals and created eight chemical panels. For each chemical, we compiled biomonitoring and toxicity data, U.S. Environmental Protection Agency exposure predictions, and annual production usage. We also applied predictive modeling to estimate toxicity. Using these data, we recommended chemicals either for biomonitoring, to be deferred pending additional data, or as low priority for biomonitoring.ResultsFor the 155 chemicals, 97 were measured in food or water, 67 in air or house dust, and 52 in biospecimens. We found in vivo endocrine, developmental, reproductive, and neurotoxic effects for 61, 74, 47, and 32 chemicals, respectively. Eighty-six had data from high-throughput in vitro assays. Positive results for endocrine, developmental, neurotoxicity, and obesity were observed for 32, 11, 35, and 60 chemicals, respectively. Predictive modeling results suggested 90% are toxicants. Biomarkers were reported for 76 chemicals. Thirty-six were recommended for biomonitoring, 108 deferred pending additional research, and 11 as low priority for biomonitoring.DiscussionThe 108 deferred chemicals included those lacking biomonitoring methods or toxicity data, representing an opportunity for future research. Our evaluation was, in general, limited by the large number of unmeasured or untested chemicals. https://doi.org/10.1289/EHP5133
Following Guidelines for Drug-Resistant Tuberculosis: âYes, itâs a challengeâ
BACKGROUND: Drug-resistant tuberculosis (DR-TB) is a major contributor to antimicrobial resistance (AMR) globally and is projected to be responsible for up to a quarter of AMR-associated deaths in the future. Management of DR-TB is increasingly decentralised to primary healthcare settings, and simultaneously becoming more complex due to a growing range of treatment options (e.g. novel agents, shorter regimens). This is reflected in the numerous recent updates to international guidelines and as such understanding the barriers and enablers to how healthcare workers access and use guidelines is vital.
MATERIAL AND METHODS: We used an established psychological framework â the theoretical domains framework (TDF) â to construct and analyse an online survey and focus groups to explore healthcare workers current use of DR-TB guidelines in South Africa. We aimed to identify barriers and enablers with which to direct future attempts at improving guideline use.
RESULTS: There were 19 responses to the online survey and 14 participants in two focus groups. 28% used the most up-to-date national guidelines, 79% accessed guidelines primarily on electronic devices. The TDF domains of âSocial Influencesâ (mean Likert score = 4.3) and âBeliefs about Consequencesâ (4.2) were key enablers, with healthcare workers encouraged to use guidelines and also recognising the value in doing so. âEnvironmental Resourcesâ (3.7) and âKnowledgeâ (3.3) were key barriers with limited, or variable access to guidelines and lack of confidence using them being notable issues. This was most noted for certain subgroups: children, HIV co-infected, pregnant women (2.7).
DISCUSSION: Current use of DR-TB guidelines in South Africa is suboptimal. Planned interventions should focus on overcoming the identified key barriers and might include an increased use of digital tools
Lack of Foraging Site Fidelity Between Years by Common Nighthawks (Chordeiles minor)
Birds in the family Caprimulgidae generally exhibit high nest site fidelity, but it is not known if fidelity extends to foraging sites, especially for Common Nighthawks (Chordeiles minor), which are otherwise one of the most studied species. Common Nighthawks are ecologically distinct from other caprimulgids, being one of the few true aerial hawking species and among the longest distance migrants in the group. We predicted these birds would exhibit fidelity between years to a foraging site in British Columbia, Canada, where they forage in large numbers on a nightly basis and the same individuals return nightly. We banded individuals and, for a subset of birds, attached transmitters programmed to activate upon return to the foraging area the next year. We estimate we marked approximately 10% of the birds foraging at the site, but did not recapture a single marked bird despite capturing potentially 50% of birds foraging at that site over the two subsequent years. Furthermore, we did not detect any of the subset of birds with radiotransmitters, indicating they did not return to the foraging site in the year following initial capture. Our data suggest low fidelity between years to a foraging site, in contrast with the published records for nesting by this species and
with the general expectations for the group.National Geographic Society || Natural Sciences and Engineering Research Council of Canada || Texas Tech University || Southern Illinois Universit
Young Radio Pulsars in Galactic Globular Clusters
Currently three isolated radio pulsars and one binary radio pulsar with no
evidence of any previous recycling are known in 97 surveyed Galactic globular
clusters. As pointed out by Lyne et al., the presence of these pulsars cannot
be explained by core-collapse supernovae, as is commonly assumed for their
counterparts in the Galactic disk. We apply a Bayesian analysis to the results
from surveys for radio pulsars in globular clusters and find the number of
potentially observable non-recycled radio pulsars present in all clusters to be
< 3600. Accounting for beaming and retention considerations, the implied birth
rate for any formation scenario for all 97 clusters is < 0.25 pulsars per
century assuming a Maxwellian distribution of velocities with a dispersion of
10 km s^{-1}. The implied birth rates for higher velocity dispersions are
substantially higher than inferred for such pulsars in the Galactic disk. This
suggests that the velocity dispersion of young pulsars in globular clusters is
significantly lower than those of disk pulsars. These numbers may be
substantial overestimates due to the fact that the currently known sample of
young pulsars is observed only in metal-rich clusters. We propose that young
pulsars may only be formed in globular clusters with metallicities with
log[Fe/H] > -0.6. In this case, the potentially observable population of such
young pulsars is 447^{+1420}_{-399} (the error bars give the 95% confidence
interval) and their birth rate is 0.012^{+0.037}_{-0.010} pulsars per century.
The mostly likely creation scenario to explain these pulsars is the electron
capture supernova of a OMgNe white dwarf.Comment: 13 Pages, 6 Figures, 4 Tables, to appear in Ap
Quantum polarization tomography of bright squeezed light
We reconstruct the polarization sector of a bright polarization squeezed beam
starting from a complete set of Stokes measurements. Given the symmetry that
underlies the polarization structure of quantum fields, we use the unique SU(2)
Wigner distribution to represent states. In the limit of localized and bright
states, the Wigner function can be approximated by an inverse three-dimensional
Radon transform. We compare this direct reconstruction with the results of a
maximum likelihood estimation, finding an excellent agreement.Comment: 15 pages, 5 figures. Contribution to New Journal of Physics, Focus
Issue on Quantum Tomography. Comments welcom
Student Satisfaction and Performance in an Online Teacher Certification Program
The article presents a study which demonstrates the effectiveness of an online post baccalaureate teacher certification program developed by a Wisconsin university. The case method approach employing multiple methods and multiple data sources were used to investigate the degree to which pre-service teachers were prepared to teach. It was concluded that the study supports online delivery as an effective means of teacher preparation, but it was limited in the number of students followed into their first year of teaching
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