112 research outputs found

    A solution to the problems of cusps and rotation curves in dark matter halos in the cosmological standard model

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    We discuss various aspects of the inner structure formation in virialized dark matter (DM) halos that form as primordial density inhomogeneities evolve in the cosmological standard model. The main focus is on the study of central cusps/cores and of the profiles of DM halo rotation curves, problems that reveal disagreements among the theory, numerical simulations, and observations. A method that was developed by the authors to describe equilibrium DM systems is presented, which allows investigating these complex nonlinear structures analytically and relating density distribution profiles within a halo both to the parameters of the initial small-scale inhomogeneity field and to the nonlinear relaxation characteristics of gravitationally compressed matter. It is shown that cosmological random motions of matter `heat up' the DM particles in collapsing halos, suppressing cusp-like density profiles within developing halos, facilitating the formation of DM cores in galaxies, and providing an explanation for the difference between observed and simulated galactic rotation curves. The analytic conclusions obtained within this approach can be confirmed by the N-body model simulation once improved spatial resolution is achieved for central halo regions.Comment: 44 pages, 16 figures, 1 tabl

    Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

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    Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting, proliferation and tissue growth to form a complex second vasculature. The Hippo pathway and effectors Yap and Taz control organ growth and regulate morphogenesis and cellular proliferation. Yap and Taz control angiogenesis but a role in lymphangiogenesis remains to be fully elucidated. Here we show that YAP displays dynamic changes in lymphatic progenitors and Yap1 is essential for lymphatic vascular development in zebrafish. Maternal and Zygotic (MZ) yap1 mutants show normal specification of lymphatic progenitors, abnormal cellular sprouting and reduced numbers of lymphatic progenitors emerging from the cardinal vein during lymphangiogenesis. Furthermore, Yap1 is indispensable for Vegfc-induced proliferation in a transgenic model of Vegfc overexpression. Paracrine Vegfc-signalling ultimately increases nuclear YAP in lymphatic progenitors to control lymphatic development. We thus identify a role for Yap in lymphangiogenesis, acting downstream of Vegfc to promote expansion of this vascular lineage.Lin Grimm, Hiroyuki Nakajima, Smrita Chaudhury, Neil I Bower, Kazuhide S Okuda, Andrew G Cox, Natasha L Harvey, Katarzyna Koltowska, Naoki Mochizuki, Benjamin M Hoga

    Active Galactic Nuclei at the Crossroads of Astrophysics

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    Over the last five decades, AGN studies have produced a number of spectacular examples of synergies and multifaceted approaches in astrophysics. The field of AGN research now spans the entire spectral range and covers more than twelve orders of magnitude in the spatial and temporal domains. The next generation of astrophysical facilities will open up new possibilities for AGN studies, especially in the areas of high-resolution and high-fidelity imaging and spectroscopy of nuclear regions in the X-ray, optical, and radio bands. These studies will address in detail a number of critical issues in AGN research such as processes in the immediate vicinity of supermassive black holes, physical conditions of broad-line and narrow-line regions, formation and evolution of accretion disks and relativistic outflows, and the connection between nuclear activity and galaxy evolution.Comment: 16 pages, 5 figures; review contribution; "Exploring the Cosmic Frontier: Astrophysical Instruments for the 21st Century", ESO Astrophysical Symposia Serie

    On the spin distributions of Λ\LambdaCDM haloes

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    We used merger trees realizations, predicted by the extended Press-Schechter theory, in order to study the growth of angular momentum of dark matter haloes. Our results showed that: 1) The spin parameter λ\lambda' resulting from the above method, is an increasing function of the present day mass of the halo. The mean value of λ\lambda' varies from 0.0343 to 0.0484 for haloes with present day masses in the range of 109h1M 10^9\mathrm{h}^{-1}M_{\odot} to 1014h1M10^{14}\mathrm{h}^{-1}M_{\odot}. 2)The distribution of λ\lambda' is close to a log-normal, but, as it is already found in the results of N-body simulations, the match is not satisfactory at the tails of the distribution. A new analytical formula that approximates the results much more satisfactorily is presented. 3) The distribution of the values of λ\lambda' depends only weakly on the redshift. 4) The spin parameter of an halo depends on the number of recent major mergers. Specifically the spin parameter is an increasing function of this number.Comment: 10 pages, 8 figure

    Extended Theories of Gravity and their Cosmological and Astrophysical Applications

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    We review Extended Theories of Gravity in metric and Palatini formalism pointing out their cosmological and astrophysical application. The aim is to propose an alternative approach to solve the puzzles connected to dark components.Comment: 44 pages, 11 figure

    On the mechanisms governing gas penetration into a tokamak plasma during a massive gas injection

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    A new 1D radial fluid code, IMAGINE, is used to simulate the penetration of gas into a tokamak plasma during a massive gas injection (MGI). The main result is that the gas is in general strongly braked as it reaches the plasma, due to mechanisms related to charge exchange and (to a smaller extent) recombination. As a result, only a fraction of the gas penetrates into the plasma. Also, a shock wave is created in the gas which propagates away from the plasma, braking and compressing the incoming gas. Simulation results are quantitatively consistent, at least in terms of orders of magnitude, with experimental data for a D 2 MGI into a JET Ohmic plasma. Simulations of MGI into the background plasma surrounding a runaway electron beam show that if the background electron density is too high, the gas may not penetrate, suggesting a possible explanation for the recent results of Reux et al in JET (2015 Nucl. Fusion 55 093013)

    Correction: “The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms” Leukemia. 2022 Jul;36(7):1720–1748

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    Overview of the JET results in support to ITER

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