112 research outputs found
A solution to the problems of cusps and rotation curves in dark matter halos in the cosmological standard model
We discuss various aspects of the inner structure formation in virialized
dark matter (DM) halos that form as primordial density inhomogeneities evolve
in the cosmological standard model. The main focus is on the study of central
cusps/cores and of the profiles of DM halo rotation curves, problems that
reveal disagreements among the theory, numerical simulations, and observations.
A method that was developed by the authors to describe equilibrium DM systems
is presented, which allows investigating these complex nonlinear structures
analytically and relating density distribution profiles within a halo both to
the parameters of the initial small-scale inhomogeneity field and to the
nonlinear relaxation characteristics of gravitationally compressed matter. It
is shown that cosmological random motions of matter `heat up' the DM particles
in collapsing halos, suppressing cusp-like density profiles within developing
halos, facilitating the formation of DM cores in galaxies, and providing an
explanation for the difference between observed and simulated galactic rotation
curves. The analytic conclusions obtained within this approach can be confirmed
by the N-body model simulation once improved spatial resolution is achieved for
central halo regions.Comment: 44 pages, 16 figures, 1 tabl
Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk
Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting, proliferation and tissue growth to form a complex second vasculature. The Hippo pathway and effectors Yap and Taz control organ growth and regulate morphogenesis and cellular proliferation. Yap and Taz control angiogenesis but a role in lymphangiogenesis remains to be fully elucidated. Here we show that YAP displays dynamic changes in lymphatic progenitors and Yap1 is essential for lymphatic vascular development in zebrafish. Maternal and Zygotic (MZ) yap1 mutants show normal specification of lymphatic progenitors, abnormal cellular sprouting and reduced numbers of lymphatic progenitors emerging from the cardinal vein during lymphangiogenesis. Furthermore, Yap1 is indispensable for Vegfc-induced proliferation in a transgenic model of Vegfc overexpression. Paracrine Vegfc-signalling ultimately increases nuclear YAP in lymphatic progenitors to control lymphatic development. We thus identify a role for Yap in lymphangiogenesis, acting downstream of Vegfc to promote expansion of this vascular lineage.Lin Grimm, Hiroyuki Nakajima, Smrita Chaudhury, Neil I Bower, Kazuhide S Okuda, Andrew G Cox, Natasha L Harvey, Katarzyna Koltowska, Naoki Mochizuki, Benjamin M Hoga
Active Galactic Nuclei at the Crossroads of Astrophysics
Over the last five decades, AGN studies have produced a number of spectacular
examples of synergies and multifaceted approaches in astrophysics. The field of
AGN research now spans the entire spectral range and covers more than twelve
orders of magnitude in the spatial and temporal domains. The next generation of
astrophysical facilities will open up new possibilities for AGN studies,
especially in the areas of high-resolution and high-fidelity imaging and
spectroscopy of nuclear regions in the X-ray, optical, and radio bands. These
studies will address in detail a number of critical issues in AGN research such
as processes in the immediate vicinity of supermassive black holes, physical
conditions of broad-line and narrow-line regions, formation and evolution of
accretion disks and relativistic outflows, and the connection between nuclear
activity and galaxy evolution.Comment: 16 pages, 5 figures; review contribution; "Exploring the Cosmic
Frontier: Astrophysical Instruments for the 21st Century", ESO Astrophysical
Symposia Serie
On the spin distributions of CDM haloes
We used merger trees realizations, predicted by the extended Press-Schechter
theory, in order to study the growth of angular momentum of dark matter haloes.
Our results showed that: 1) The spin parameter resulting from the
above method, is an increasing function of the present day mass of the halo.
The mean value of varies from 0.0343 to 0.0484 for haloes with
present day masses in the range of to
. 2)The distribution of is close to
a log-normal, but, as it is already found in the results of N-body simulations,
the match is not satisfactory at the tails of the distribution. A new
analytical formula that approximates the results much more satisfactorily is
presented. 3) The distribution of the values of depends only weakly
on the redshift. 4) The spin parameter of an halo depends on the number of
recent major mergers. Specifically the spin parameter is an increasing function
of this number.Comment: 10 pages, 8 figure
Extended Theories of Gravity and their Cosmological and Astrophysical Applications
We review Extended Theories of Gravity in metric and Palatini formalism
pointing out their cosmological and astrophysical application. The aim is to
propose an alternative approach to solve the puzzles connected to dark
components.Comment: 44 pages, 11 figure
Seasonal acclimatization to temperature in cardueline finches
1. Seasonal variation in body constituents and utilization of lipid, protein, and carbohydrate during cold stress in American goldfinches were studied to determine relations of these functions to the pronounced seasonal shift in thermogenic capacity documented in a previous study (Dawson and Carey, 1976).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47119/1/360_2004_Article_BF00686746.pd
On the mechanisms governing gas penetration into a tokamak plasma during a massive gas injection
A new 1D radial fluid code, IMAGINE, is used to simulate the penetration of gas into a tokamak plasma during a massive gas injection (MGI). The main result is that the gas is in general strongly braked as it reaches the plasma, due to mechanisms related to charge exchange and (to a smaller extent) recombination. As a result, only a fraction of the gas penetrates into the plasma. Also, a shock wave is created in the gas which propagates away from the plasma, braking and compressing the incoming gas. Simulation results are quantitatively consistent, at least in terms of orders of magnitude, with experimental data for a D 2 MGI into a JET Ohmic plasma. Simulations of MGI into the background plasma surrounding a runaway electron beam show that if the background electron density is too high, the gas may not penetrate, suggesting a possible explanation for the recent results of Reux et al in JET (2015 Nucl. Fusion 55 093013)
Cytokine gene expression and molecular detection of Mycobacterium avium subspecies paratuberculosisin organs of experimentally infected mice
Correction: “The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms” Leukemia. 2022 Jul;36(7):1720–1748
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