The sub-mJy radio sky in the Extended Chandra Deep Field South: source population

The sub-mJy radio population is a mixture of active systems, that is star forming galaxies (SFGs) and active galactic nuclei (AGNs). We study a sample of 883 radio sources detected at 1.4 GHz in a deep Very Large Array survey of the Extended Chandra Deep Field South (E-CDFS) that reaches a best rms sensitivity of 6 microJy. We have used a simple scheme to disentangle SFGs, radio-quiet (RQ), and radio-loud (RL) AGNs based on the combination of radio data with Chandra X-ray data and mid-infrared observations from Spitzer. We find that at flux densities between about 30 and 100 microJy the radio population is dominated by SFGs (~60%) and that RQ AGNs become increasingly important over RL ones below 100 microJy. We also compare the host galaxy properties of the three classes in terms of morphology, optical colours and stellar masses. Our results show that both SFG and RQ AGN host galaxies have blue colours and late type morphology while RL AGNs tend to be hosted in massive red galaxies with early type morphology. This supports the hypothesis that radio emission in SFGs and RQ AGNs mainly comes from the same physical process: star formation in the host galaxy.Comment: 13 pages, 11 figures, 1 table, accepted for publication in MNRA

Star formation properties of sub-mJy radio sources

We investigate the star formation properties of ~800 sources detected in one of the deepest radio surveys at 1.4 GHz. Our sample spans a wide redshift range (~0.1 - 4) and about four orders of magnitude in star formation rate (SFR). It includes both star forming galaxies (SFGs) and active galactic nuclei (AGNs), further divided into radio-quiet and radio-loud objects. We compare the SFR derived from the far infrared luminosity, as traced by Herschel, with the SFR computed from their radio emission. We find that the radio power is a good SFR tracer not only for pure SFGs but also in the host galaxies of RQ AGNs, with no significant deviation with redshift or specific SFR. Moreover, we quantify the contribution of the starburst activity in the SFGs population and the occurrence of AGNs in sources with different level of star formation. Finally we discuss the possibility of using deep radio survey as a tool to study the cosmic star formation history.Comment: 18 pages, 14 figures, 1 table (available in its entirety as ancillary data

The VLA 1.4GHz Survey of the Extended Chandra Deep Field South: Second Data Release

Deep radio observations at 1.4GHz for the Extended Chandra Deep Field South were performed in June through September of 2007 and presented in a first data release (Miller et al. 2008). The survey was made using six separate pointings of the Very Large Array (VLA) with over 40 hours of observation per pointing. In the current paper, we improve on the data reduction to produce a second data release (DR2) mosaic image. This DR2 image covers an area of about a third of a square degree and reaches a best rms sensitivity of 6 uJy and has a typical sensitivity of 7.4 uJy per 2.8" by 1.6" beam. We also present a more comprehensive catalog, including sources down to peak flux densities of five or more times the local rms noise along with information on source sizes and relevant pointing data. We discuss in some detail the consideration of whether sources are resolved under the complication of a radio image created as a mosaic of separate pointings each suffering some degree of bandwidth smearing, and the accurate evaluation of the flux densities of such sources. Finally, the radio morphologies and optical/near-IR counterpart identifications (Bonzini et al. 2012) are used to identify 17 likely multiple-component sources and arrive at a catalog of 883 radio sources, which is roughly double the number of sources contained in the first data release.Comment: to appear in the Astrophysical Journal Supplement Series; 41 page

Out-of-hospital cardiac arrests in a large metropolitan area : synergistic effect of exposure to air particulates and high temperature

Aims: Air pollution and climate change are intrinsically linked to emerging hazards for global health. High air particulate matter (PM) levels may trigger out-of-hospital cardiac arrest (OHCA). High temperature could act synergistically with PM in determining OHCA. The aim of the present study was to investigate the effect of PM exposure alone, and in combination with temperature, on the risk of OHCA, in a large European metropolitan area with population >4 million. Methods: We evaluated the association between short-term PM exposure, temperature, and the risk of OHCA over a two-year study period, allowing us to investigate 5761 events using a time-stratified case-crossover design combined with a distributed lag non-linear model. Results: Higher risk of OHCA was associated with short-term exposure to PM10. The strongest association was experienced three days before the cardiac event where the estimated change in risk was 1.70% (0.48\u20132.93%) per 10 \ub5g/m3 of PM. The cumulative exposure risk over the lags 0\u20136 was 8.5% (0.0\u201317.9%). We observed a joint effect of PM and temperature in triggering cardiac arrests, with a maximum effect of 14.9% (10.0\u201320.0%) increase, for high levels of PM before the cardiac event, in the presence of high temperature. Conclusion: The present study helps to clarify the controversial role of PM as OHCA determinant. It also highlights the role of increased temperature as a key factor in triggering cardiac events. This evidence suggests that tackling both air pollution and climate change might have a relevant impact in terms of public health

Linking the X-ray and infrared properties of star-forming galaxies at z < 1.5

We present the most complete study to date of the X-ray emission from star formation in high-redshift (median z = 0.7; z −3 in both hard and soft X-ray bands. From the sources which are star formation dominated, only a small fraction are individually X-ray detected and for the bulk of the sample we calculate average X-ray luminosities through stacking. We find an average soft X-ray to infrared ratio of log ?L SX /L IR ? = −4.3 and an average hard X-ray to infrared ratio of log?L HX /L IR ?=−3.8.WereportthattheX-ray/IRcorrelationisapproximatelylinearthrough the entire range of L IR and z probed and, although broadly consistent with the local (z < 0.1) one, it does display some discrepancies. We suggest that these discrepancies are unlikely to be physical, i.e. due to an intrinsic change in the X-ray properties of star-forming galaxies with cosmic time, as there is no significant evidence for evolution of the L X /L IR ratio with redshift. Instead, they are possibly due to selection effects and remaining AGN contamination. We also examine whether dust obscuration in the galaxy plays a role in attenuating X-rays from star formation, by investigating changes in the L X /L IR ratio as a function of the average dust temperature. We conclude that X-rays do not suffer any measurable attenuation in the host galaxy

Exploring the Prognostic Role of Ki67 Proliferative Index in Merkel Cell Carcinoma of the Skin: Clinico-Pathologic Analysis of 84 Cases and Review of the Literature.

The exact prediction of outcome of patients with Merkel cell carcinoma (MCC) of the skin is difficult to determine, although several attempts have been made to identify clinico-pathologic prognostic factors. The Ki67 proliferative index is a well-known marker routinely used to define the prognosis of patients with neuroendocrine neoplasms. However, its prognostic value has been poorly investigated in MCC, and available published results are often contradictory mainly because restricted to small series in the absence of standardized methods for Ki67 evaluation. For this reason, we explored the potential prognostic role of Ki67 proliferative index in a large series of MCCs using the WHO standardized method of counting positive cells in at least 500 tumor cells in hot spot areas on camera-captured printed images. In addition, since MCC may be considered as the cutaneous counterpart of digestive neuroendocrine carcinomas (NECs), we decided to stratify MCCs using the available and efficient Ki67 threshold of 55%, which was found prognostic in digestive NECs. This choice was also supported by the Youden index analysis. In addition, we analyzed the prognostic value of other clinico-pathologic parameters using both univariate and multivariate analysis. Ki67 index appeared significantly associated with prognosis at univariate analysis together with stage IV, lack of MCPyV, and p63 expression, but not at the multivariate analysis, where survival resulted independently influenced by p63 expression and tumor stage, only

Association between leukocyte telomere shortening and exposure to traffic pollution: a cross-sectional study on traffic officers and indoor office workers

BACKGROUND: Telomere shortening in blood leukocytes has been associated with increased morbidity and death from cardiovascular disease and cancer, but determinants of shortened telomeres, a molecular feature of biological aging, are still largely unidentified. Traffic pollution has been linked with both cardiovascular and cancer risks, particularly in older subjects. Whether exposure to traffic pollution is associated with telomere shortening has never been evaluated. METHODS: We measured leukocyte telomere length (LTL) by real-time PCR in blood DNA from 77 traffic officers exposed to high levels of traffic pollutants and 57 office workers (referents). Airborne benzene and toluene, as tracers for traffic exposure, were measured using personal passive samplers and gas-chromatography/flame-ionization detector analysis. We used covariate-adjusted multivariable models to test the effects of the exposure on LTL and obtain adjusted LTL means and 95\% Confidence Intervals (CIs). RESULTS: Adjusted mean LTL was 1.10 (95\%CI 1.04-1.16) in traffic officers and 1.27 in referents (95\%CI 1.20-1.35) [p < 0.001]. LTL decreased in association with age in both traffic officers (p = 0.01) and referents (p = 0.001), but traffic officers had shorter LTL within each age category. Among traffic officers, adjusted mean relative LTL was shorter in individuals working in high (n = 45, LTL = 1.02, 95\%CI 0.96-1.09) compared to low traffic intensity (n = 32, LTL = 1.22, 95\%CI 1.13-1.31) [p < 0.001]. In the entire study population, LTL decreased with increasing levels of personal exposure to benzene (p = 0.004) and toluene (p = 0.008). CONCLUSION: Our results indicate that leukocyte telomere length is shortened in subjects exposed to traffic pollution, suggesting evidence of early biological aging and disease risk

VizieR Online Data Catalog: ECDFS sources optical/IR counterparts (Bonzini+, 2013)

We consider a sample of 883 radio sources detected at 1.4GHz in a deep Very Large Array (VLA) survey of the Extended Chandra Deep Field-South (E-CDFS) that reaches a best rms sensitivity of 6uJy. We used deep Spitzer InfraRed Array Camera (IRAC) and Multiband Imaging Photometer for Spitzer (MIPS) data. The IRAC data were obtained as part of the Spitzer IRAC/MUSYC Public Legacy Survey in the Extended CDF-South (SIMPLE) survey (Damen et al., 2011ApJ...727....1D, Cat. J/ApJ/727/1). It covers an area of about 1600 arcmin2 centred on the E-CDFS. The typical 5σ flux density limits are 1.1, 1.3, 6.3 and 7.6uJy at 3.6, 4.5, 5.8 and 8.0um, respectively. We also use MIPS 24um data from the Far-Infrared Deep Extragalactic Legacy (FIDEL) survey (Dickinson & FIDEL Team, 2007AAS...211.5216D). The E-CDFS has been mapped in the X-ray band by Chandra. A total of 129 radio sources have a counterpart in the 4 Ms observations of the CDFS presented in Xue et al. (2011ApJS..195...10X, Cat. J/ApJS/195/10) and another 99 in the main E-CDFS catalogue by Lehmer et al. (2005ApJS..161...21L, Cat. J/ApJS/161/21) obtained with shallower (250ks) observations in each of four pointings. The list of the X-ray counterparts of the radio sources is given in Bonzini et al. (2012ApJS..203...15B, Cat. J/ApJS/203/15)