105 research outputs found
Object Oriented Terrain Databases For Visual Simulators
Report on a project to develop methodologies and solutions to the problem of representation and utilization of dynamic terrain on a real-time simulator
Killing tensors in pp-wave spacetimes
The formal solution of the second order Killing tensor equations for the
general pp-wave spacetime is given. The Killing tensor equations are integrated
fully for some specific pp-wave spacetimes. In particular, the complete
solution is given for the conformally flat plane wave spacetimes and we find
that irreducible Killing tensors arise for specific classes. The maximum number
of independent irreducible Killing tensors admitted by a conformally flat plane
wave spacetime is shown to be six. It is shown that every pp-wave spacetime
that admits an homothety will admit a Killing tensor of Koutras type and, with
the exception of the singular scale-invariant plane wave spacetimes, this
Killing tensor is irreducible.Comment: 18 page
Measuring Small Distances in N=2 Sigma Models
We analyze global aspects of the moduli space of K\"ahler forms for =(2,2)
conformal -models. Using algebraic methods and mirror symmetry we study
extensions of the mathematical notion of length (as specified by a K\"ahler
structure) to conformal field theory and calculate the way in which lengths
change as the moduli fields are varied along distinguished paths in the moduli
space. We find strong evidence supporting the notion that, in the robust
setting of quantum Calabi-Yau moduli space, string theory restricts the set of
possible K\"ahler forms by enforcing ``minimal length'' scales, provided that
topology change is properly taken into account. Some lengths, however, may
shrink to zero. We also compare stringy geometry to classical general
relativity in this context.Comment: 62 pp. with 6 figs., LaTeX and epsf.te
Group Process and Organizational Environment: Student Organizations in the University
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68768/2/10.1177_089976407400300305.pd
Simulation of Drosophila Circadian Oscillations, Mutations, and Light Responses by a Model with VRI, PDP-1, and CLK
A model of Drosophila circadian rhythm generation was developed to represent
feedback loops based on transcriptional regulation of per, Clk (dclock), Pdp-1,
and vri (vrille). The model postulates that histone acetylation kinetics make
transcriptional activation a nonlinear function of [CLK]. Such a nonlinearity
is essential to simulate robust circadian oscillations of transcription in our
model and in previous models. Simulations suggest two positive feedback loops
involving Clk are not essential for oscillations, because oscillations of [PER]
were preserved when Clk, vri, or Pdp-1 expression was fixed. Eliminating the
negative feedback loop in which PER represses per expression abolished
oscillations. Simulations of per or Clk null mutations and of vri, Clk, or
Pdp-1 heterozygous null mutations altered model behavior in ways similar to
experimental data. The model simulated a photic phase-response curve resembling
experimental curves, and oscillations entrained to simulated light-dark cycles.
The model makes experimental predictions, some of which could be tested in
transgenic Drosophila.Comment: Accepted to Biophysical Journal, 1/16/04. Single PDF file, 7 figures
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Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone
The 2013-2015 Ebola virus disease (EVD) epidemic is caused by the Makona variant of Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus evolution and transmission and offered important information for outbreak response. Here, we analyze sequences from 232 patients sampled over 7 months in Sierra Leone, along with 86 previously released genomes from earlier in the epidemic. We confirm sustained human-to-human transmission within Sierra Leone and find no evidence for import or export of EBOV across national borders after its initial introduction. Using high-depth replicate sequencing, we observe both host-to-host transmission and recurrent emergence of intrahost genetic variants. We trace the increasing impact of purifying selection in suppressing the accumulation of nonsynonymous mutations over time. Finally, we note changes in the mucin-like domain of EBOV glycoprotein that merit further investigation. These findings clarify the movement of EBOV within the region and describe viral evolution during prolonged human-to-human transmission
Missing Links: Referrer Behavior and Job Segregation
How does referral recruitment contribute to job segregation, and what can organizations do about it?
Current theory on network effects in the labor market emphasizes the job-seeker perspective, focusing on the
segregated nature of job-seekersâ information and contact networks, and leaves little role for organizational
influence. But employee referrals are necessarily initiated from within a firm by referrers. We argue that
referrer behavior is the missing link that can help organizations manage the segregating effects of referring.
Adopting the referrerâs perspective of the process, we develop a computational model which integrates a set
of empirically documented referrer behavior mechanisms gleaned from extant organizational case studies.
Using this model, we compare the segregating effects of referring when these behaviors are inactive to the
effects when the behaviors are active. We show that referrer behaviors substantially boost the segregating
effects of referring. This impact of referrer behavior presents an opportunity for organizations. Contrary to
popular wisdom, we show that organizational policies designed to influence referrer behaviors can mitigate
most if not all of the segregating effects of referring
Implementation of Evidence-Based Practice in Community Behavioral Health: Agency Director Perspectives
Despite a growing supply of evidence-based mental health treatments, we have little evidence about how to implement them in real-world care. This qualitative pilot study captured the perspectives of agency directors on the challenge of implementing evidence-based practices in community mental health agencies. Directors identified challenges as limited access to research, provider resistance, and training costs. Director leadership, support to providers, and partnerships with universities were leverage points to implement evidenced-based treatments. Directorsâ mental models of EBP invoked such concepts as agency reputation, financial solvency, and market niche. Findings have potential to shape implementation interventions.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/61161/1/Implementation.pd
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