Future changes in tropical cyclone activity in the North Indian Ocean projected by high-resolution MRI-AGCMs

Open Access at publisher's web site: http://www.springerlink.com/content/b682734237171631

2022 report from the Auger-TA working group on UHECR arrival directions

After over 60 years, the powerful engines that accelerate ultra-high-energy cosmic rays (UHECRs) to the formidable energies at which we observe them from Earth remain mysterious. Assuming standard physics, we expect UHECR sources to lie within the local Universe (up to a few hundred~Mpc). The distribution of matter in the local Universe is anisotropic, and we expect this anisotropy to be imprinted on the distribution of UHECR arrival directions. Even though intervening intergalactic and Galactic magnetic fields deflect charged UHECRs and can distort these anisotropies, some amount of information on the distribution of the sources is preserved. In this proceedings contribution, we present the results of the joint Pierre Auger Observatory and Telescope Array searches for (a) the largest-scale anisotropies (the harmonic dipole and quadrupole) and (b) correlations with a sample of nearby starburst galaxies and the 2MRS catalogue tracing stellar mass within~250~Mpc. This analysis updates our previous results with the most recent available data, notably with the addition of 3~years of new Telescope Array data. The main finding is a correlation between the arrival directions of $12.1\%_{-3.1\%}^{+4.5\%}$~of UHECRs detected with $E \geq 38$~EeV by~Auger or with~$E \gtrsim 49$~EeV by~TA and the positions of nearby starburst galaxies on a ${15.1\text{deg}}_{-3.0\text{deg}}^{+4.6\text{deg}}$~angular scale, with a $4.7\sigma$~post-trial significance, up from $4.2\sigma$ obtained in our previous study.Comment: proceedings of the 6th International Symposium on Ultra High Energy Cosmic Rays (UHECR2022), 3-7 October 2022, L'Aquila, Ital

Phenomenology of convection-parameterization closure

Peer reviewe

Putting to rest WISHE-ful misconceptions for tropical cyclone intensification

The purpose of this article is twofold. The first is to point out and correct several misconceptions about the putative WISHE mechanism of tropical cyclone intensification that currently are being taught to atmospheric science students, to tropical weather forecasters, and to laypeople who seek to understand how tropical cyclones intensify. The mechanism relates to the simplest problem of an initial cyclonic vortex in a quiescent environment. This first part is important because the credibility of tropical cyclone science depends inter alia on being able to articulate a clear and consistent picture of the hypothesized intensification process and its dependencies on key flow parameters. The credibility depends also on being able to test the hypothesized mechanisms using observations, numerical models, or theoretical analyses. The second purpose of the paper is to carry out new numerical experiments using a state-of-the-art numerical model to test a recent hypothesis invoking the WISHE feedback mechanism during the rapid intensification phase of a tropical cyclone. The results obtained herein, in conjunction with prior work, do not support this recent hypothesis and refute the view that the WISHE intensification mechanism is the essential mechanism of tropical cyclone intensification in the idealized problem that historically has been used to underpin the paradigm. This second objective is important because it presents a simple way of testing the hypothesized intensification mechanism and shows that the mechanism is neither essential nor the dominant mode of intensification for the prototype intensification problem. In view of the operational, societal, and scientific interest in the physics of tropical cyclone intensification, we believe this paper will be of broad interest to the atmospheric science community and the findings should be useful in both the classroom setting and frontier research

MMP28 (epilysin) as a novel promoter of invasion and metastasis in gastric cancer

Background\ud The purpose of this study was to investigate invasion and metastasis related genes in gastric cancer.\ud \ud Methods\ud The transwell migration assay was used to select a highly invasive sub-line from minimally invasive parent gastric cancer cells, and gene expression was compared using a microarray. MMP28 upregulation was confirmed using qRT-PCR. MMP28 immunohistochemistry was performed in normal and gastric cancer specimens. Invasiveness and tumor formation of stable cells overexpressing MMP28 were tested in vitro and in vivo.\ud \ud Results\ud MMP28 was overexpressed in the highly invasive sub-cell line. Immunohistochemistry revealed MMP28 expression was markedly increased in gastric carcinoma relative to normal epithelia, and was significantly associated with depth of tumor invasion, lymph node metastasis and poorer overall survival. Ectopic expression of MMP28 indicated MMP28 promoted tumor cell invasion in vitro and increased gastric carcinoma metastasis in vivo.\ud \ud Conclusions\ud This study indicates MMP28 is frequently overexpressed during progression of gastric carcinoma, and contributes to tumor cell invasion and metastasis. MMP28 may be a novel therapeutic target for prevention and treatment of metastases in gastric cancer

Design, upgrade and characterization of the silicon photomultiplier front-end for the AMIGA detector at the Pierre Auger Observatory

AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory to complement the study of ultra-high-energy cosmic rays (UHECR) by measuring the muon content of extensive air showers (EAS). It consists of an array of 61 water Cherenkov detectors on a denser spacing in combination with underground scintillation detectors used for muon density measurement. Each detector is composed of three scintillation modules, with 10 m2 detection area per module, buried at 2.3 m depth, resulting in a total detection area of 30 m2. Silicon photomultiplier sensors (SiPM) measure the amount of scintillation light generated by charged particles traversing the modules. In this paper, the design of the front-end electronics to process the signals of those SiPMs and test results from the laboratory and from the Pierre Auger Observatory are described. Compared to our previous prototype, the new electronics shows a higher performance, higher efficiency and lower power consumption, and it has a new acquisition system with increased dynamic range that allows measurements closer to the shower core. The new acquisition system is based on the measurement of the total charge signal that the muonic component of the cosmic ray shower generates in the detector

Studies on the response of a water-Cherenkov detector of the Pierre Auger Observatory to atmospheric muons using an RPC hodoscope

Extensive air showers, originating from ultra-high energy cosmic rays, have been successfully measured through the use of arrays of water-Cherenkov detectors (WCDs). Sophisticated analyses exploiting WCD data have made it possible to demonstrate that shower simulations, based on different hadronic-interaction models, cannot reproduce the observed number of muons at the ground. The accurate knowledge of the WCD response to muons is paramount in establishing the exact level of this discrepancy. In this work, we report on a study of the response of a WCD of the Pierre Auger Observatory to atmospheric muons performed with a hodoscope made of resistive plate chambers (RPCs), enabling us to select and reconstruct nearly 600 thousand single muon trajectories with zenith angles ranging from 0 to 55. Comparison of distributions of key observables between the hodoscope data and the predictions of dedicated simulations allows us to demonstrate the accuracy of the latter at a level of 2%. As the WCD calibration is based on its response to atmospheric muons, the hodoscope data are also exploited to show the long-term stability of the procedure

Design, upgrade and characterization of the silicon photomultiplier front-end for the AMIGA detector at the Pierre Auger Observatory

AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory to complement the study of ultra-high-energy cosmic rays (UHECR) by measuring the muon content of extensive air showers (EAS). It consists of an array of 61 water Cherenkov detectors on a denser spacing in combination with underground scintillation detectors used for muon density measurement. Each detector is composed of three scintillation modules, with 10 m2 detection area per module, buried at 2.3 m depth, resulting in a total detection area of 30 m2 . Silicon photomultiplier sensors (SiPM) measure the amount of scintillation light generated by charged particles traversing the modules. In this paper, the design of the front-end electronics to process the signals of those SiPMs and test results from the laboratory and from the Pierre Auger Observatory are described. Compared to our previous prototype, the new electronics shows a higher performance, higher efficiency and lower power consumption, and it has a new acquisition system with increased dynamic range that allows measurements closer to the shower core. The new acquisition system is based on the measurement of the total charge signal that the muonic component of the cosmic ray shower generates in the detector.Fil: Aab, A.. Radboud Universiteit Nijmegen; Países BajosFil: Abreu, P.. Instituto Superior Tecnico; PortugalFil: Aglietta, M.. Istituto Nazionale di Astrofisica; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Albury, J. M.. University of Adelaide; AustraliaFil: Allekotte, Ingomar. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; ArgentinaFil: Almela, A.. Universidad Nacional de San Martín; Argentina. Universidad Tecnológica Nacional; ArgentinaFil: Alvarez Muñiz, J.. Universidad de Santiago de Compostela; EspañaFil: Alves Batista, R.. Radboud Universiteit Nijmegen; Países BajosFil: Anastasi, G. A.. Università di Torino; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Anchordoqui, Luis A.. City University of New York; Estados UnidosFil: Andrada, Betiana Eugenia. Universidad Nacional de San Martín; ArgentinaFil: Andringa, S.. Instituto Superior Tecnico; PortugalFil: Aramo, C.. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Araújo Ferreira, P. R.. Rwth Aachen University; AlemaniaFil: Asorey, H.. Universidad Nacional de San Martín; ArgentinaFil: Assis, P.. Instituto Superior Tecnico; PortugalFil: Avila, G.. Observatorio Pierre Auger; ArgentinaFil: Badescu, A. M.. University Politehnica Of Bucharest; RumaniaFil: Bakalova, A.. The Czech Academy Of Sciences; República ChecaFil: Balaceanu, A.. “Horia Hulubei” National Institute for Physics and Nuclear Engineering, Bucharest-Magurele; RumaniaFil: Barbato, F.. Università degli Studi di Napoli Federico II; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Barreira Luz, R. J.. Instituto Superior Tecnico; PortugalFil: Becker, K. H.. Bergische Universität Wuppertal; AlemaniaFil: Bellido, J. A.. University of Adelaide; AustraliaFil: Berat, C.. Universite Grenoble Alpes; FranciaFil: Bertaina, M. E.. Università di Torino; Italia. Istituto Nazionale di Fisica Nucleare; ItaliaFil: Bertou, Xavier Pierre Louis. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; ArgentinaFil: Biermann, P. L.. Max Planck Institute For Radio Astronomy; AlemaniaFil: Bister, T.. Rwth Aachen University; AlemaniaFil: Gollan Scilipotti, Fernando Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Tecnología en Detección y Astropartículas. Comisión Nacional de Energía Atómica. Instituto de Tecnología en Detección y Astropartículas. Universidad Nacional de San Martín. Instituto de Tecnología en Detección y Astropartículas; Argentin

Reconstruction of events recorded with the surface detector of the Pierre Auger Observatory

Cosmic rays arriving at Earth collide with the upper parts of the atmosphere, thereby inducing extensive air showers. When secondary particles from the cascade arrive at the ground, they are measured by surface detector arrays. We describe the methods applied to the measurements of the surface detector of the Pierre Auger Observatory to reconstruct events with zenith angles less than 60 using the timing and signal information recorded using the water-Cherenkov detector stations. In addition, we assess the accuracy of these methods in reconstructing the arrival directions of the primary cosmic ray particles and the sizes of the induced showers