Reconciling the stratigraphy and depositional history of the Lycian orogen-top basins, SW Anatolia

Terrestrial fossil records from the SWAnatolian basins are crucial both for regional correlations and palaeoenvironmental reconstructions. By reassessing biostratigraphic constraints and incorporating new fossil data, we calibrated and reconstructed the late Neogene andQuaternary palaeoenvironments within a regional palaeogeographical framework. The culmination of the Taurides inSWAnatolia was followed by a regional crustal extension from the late Tortonian onwards that created a broad array of NE-trending orogen-top basins with synchronic associations of alluvial fan, fluvial and lacustrine deposits. The terrestrial basins are superimposed on the upper Burdigalian marine units with a c. 7 myr of hiatus that corresponds to a shift from regional shortening to extension. The initial infill of these basins is documented by a transition from marginal alluvial fans and axial fluvial systems into central shallow-perennial lakes coinciding with a climatic shift from warm/humid to arid conditions. The basal alluvial fan deposits abound in fossil macro-mammals of an early Turolian (MN11–12; late Tortonian) age. The Pliocene epoch in the region was punctuated by subhumid/humid conditions resulting in a rise of local base levels and expansion of lakes as evidenced by marsh-swamp deposits containing diverse fossilmammal assemblages indicating late Ruscinian (lateMN15; late Zanclean) ageWe are grateful for the support of the international bilateral project between The Scientific and Technological Research Council of Turkey (TUBITAK) and The Russian Scientific Foundation (RFBR) with grant a number of 111Y192. M.C.A. is grateful to the Turkish Academy of Sciences (TUBA) for a GEBIP (Young Scientist Award) grant. T.K. and S.M. are grateful to the Ege University Scientific Research Center for the TTM/002/2016 and TTM/001/2016 projects. M.C.A., H.A., S.M. and M.B. have obtained Martin and Temmick Fellowships at Naturalis Biodiversity Center (Leiden). F.A.D. is supported by a Mehmet Akif Ersoy University Scientific Research Grant. T.A.N. is supported by an Alexander-von-Humboldt Scholarship. L.H.O. received support from TUBITAK under the 2221 program for visiting scientists

Investigation Of Electronic Portal Imaging Based In-Vivo Dose Verification For Prostate Sbrt

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A Feasibility Study Of Epid-Based In-Vivo Dosimetry System In Machine Specific Quality Assurance

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Application Of Extended Ct Scale And Metal Artefact Reduction Methods On Radiotherapy Planning

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Dosimetric And Mechanical Stability Of Cyberknife Robotic Radiosurgery Unit: 5 Years’ Clinical Experience

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Subdermal nitrous oxide delivery increases skin microcirculation and random flap survival in rats

Random skin flaps are essential tools in reconstructive surgery. In this study, we investigated the effect of subdermal nitrous oxide (N2O) application on random flap survival. In this experimental study, we used 21 female rats in three groups. In the N2O and air groups, gases were administrated under the proposed dorsal flap areas daily for seven days. Following the treatment period, flaps were raised and inserted back into their place from the dorsal skin. In the control group, the flaps were elevated and inserted back to their place without any pretreatment. Calculation of necrotic flap areas, histological examination and microangiography was performed to evaluate the results 7 days after the flap surgery. The average of necrotic flap area in the N2O, air and control group was 13.45%, 37.67% and 46.43%, respectively. (N2O vs air p = .044; N2O vs control p = .003). The average number of capillary formations identified in the histological analysis was 7.0 +/- 1.58, 3.75 +/- 2.36 and 4.4 +/- 0.54 in the N2O, air and control group, respectively. (N2O vs air p = .017; N2O vs control p = .037). The average number of capillary structures identified in the angiography images were 6.3 +/- 1.52, 1.6 +/- 1.15 and 1.3 +/- 0.57 in the N2O, air and control group, respectively. (N2O vs air p = .04; N2O vs control p = .02). We conclude that subdermal N2O application increases random flap survival through an increase in the skin microcirculation and could be promising for future clinical applications

Late Pleistocene–Holocene evolution of the northern shelf of the Sea of Marmara

Chirp sub-bottom profiling, multibeam bathymetric mapping and a combination of faunal and isotopic analysis of molluscs and foraminifera in sediment cores on the northern shelf of the Sea of Marmara (SoM) provide evidence of sea-level excursions, water exchanges between the adjacent Mediterranean and Black Seas, and oscillating salinity over the last 160ka bp. During the marine isotope stages MIS-2, MIS-3, MIS-4 and MIS-6 the SoM disconnected from the Mediterranean Sea and evolved into a lake. During MIS-1, MIS-5 and MIS-7, the SoM reconnected and became salty once again. Sapropels formed shortly after each invasion of Mediterranean saltwater observed in our cores. Concurrent suboxic–dysoxic conditions prevailed over quite shallow substrates on the shelf. Ancient shorelines are pervasive at −85m on the northern shelf and in the region of Prince Islands coincident with the elevation of the modern bedrock sill in the Çanakkale (Dardanelles) Strait. At times when global (eustatic) sea level dropped below this sill, the surface of the SoM stabilized at its outlet and freshened. Thus this particular shoreline is interpreted as the edge of the most recent SoM lake that existed from about 75ka bp to 12ka bp. The freshening is observed in very light (−6‰) values of δ18O measured on freshwater molluscs and the complete absence of foraminifera. Two brief lacustrine episodes during MIS-5 suggest that the level of the Çanakkale outlet might have been as shallow as −50m in the past, a likelihood supported by submerged terraces along its margins bounding the modern central channel and the presence of an euryhaline biofacies in Unit L4.1 corresponding to MIS-5b. δ18O profiles and carbon-14 dating show that salinification of the SoM and the blossoming of bioherms evolved rapidly after the latest connection with the Mediterranean at 12ka bp. However, freshening proceeded more slowly once the connection was severed