PSICOMOTRICIDADE E EDUCAÇÃO MUSICAL: REFLEXÕES PARA O DESENVOLVIMENTO PSICOMOTOR DA CRIANÇA ATRAVÉS DO MÉTODO DE DALCROZE

O presente artigo tem como objetivo refletir, através de um estudo bibliográfico, sobre a relação entre a educação musical e a psicomotricidade, a partir do método de Dalcroze e do campo de educação psicomotora - Psicomotricidade Funcional. Aproximando as referidas vertentes e destacando propostas de atividades que podem contribuir para o desenvolvimento psicomotor da criança, pretendeu-se também ampliar as possibilidades de realização de um trabalho pedagógico por parte de professores de música e professores de escolas de educação infantil no que tange a utilização do lúdico, e respeitando a capacidade cognitiva, afetiva, social, emocional e motora da criança de acordo com a sua faixa etária

Combination of Melatonin and Metformin Hydrochloride for Treatment Polycystic Ovarian in Female Rats

Background: Polycystic ovary syndrome (PCOS) is a gynecological endocrine disorder, results in menstrual abnormalities, androgynism and infertility. In the case of women or others animals with PCOS wishing to treat infertility with the aim of becoming pregnant, the most commonly used is metformin hydrochloride. Recent studies have analyzed the combination of metformin hydrochloride with melatonin in oncological treatment but not to treatment of polycystic ovary syndrome (PCOS). The aim of the present study was to analyze the effectiveness of the combination of metformin hydrochloride and melatonin in the treatment of PCOS to improve the fertility of rats and your hormonal alterations.Materials, Methods & Results: This study was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. The protocol was approved by the Committee on the Ethics of Animal Experiments of the University of Federal Rural of Pernambuco (Permit Number: 23081.009130/2010). A total of 50 albino Wistar rats were used. The animal laboratory of an academic research environment, were randomly separated into five groups consisting of 10 females each. After inducing PCOS, the rats were treated with metformin hydrochloride, and/or melatonin, and the results compared with standard and ultrasound confirmed. The physiological similarities were confirmed by our academic researchers morphological science, and published to the association results of effects syndrome induction through constant lighting in reputable magazine recently. This article was analyzed histological of the implantation sites and ovaries, and the estradiol and progesterone levels on the seventh day of gestation, and the other rats for monitoring pregnancy and morphological identification of possible fetal abnormalities, weight measurement and quantification of offspring. The rats were anaesthetized with intraperitoneal injections of ketamine hydrochloride (80 mg/kg) and xylazine (6 mg/kg) to allow analysis of the reproductive organs. Main outcome measures: The study included histopathology, histochemical and quantitative (of the implantation sites) tests, ultrasound analysis, weight benchmarking and ovarian histology tests, as well as comparison of serum estradiol and progesterone levels, and the morphological assessment of offspring. Results paper shows pharmacological treatment reduced the time needed for pregnancy, increased the plasma progesterone levels, the number and weight of offspring, and reduced plasma estrogen levels and collagen fiber grade, improving blastocyst-endometrium interaction and fetal development.Discussion: Our team of researchers confirmed in a previous paper; in addition, the main experimental model used in research about PCOS in recent years, and considered appropriate combination of the drugs caused a physiological reaction similar to responses identified in healthy rats without induction of the POS control group. However, the clinical and physiological effectiveness of the combination should be further explored, especially with respect to the possible side effects on offspring. The treatment with a combination of metformin hydrochloride and melatonin was more effective against hormonal alterations produced by PCOS, allowing a normalization of biochemical parameters during pregnancy, than monotherapeutic treatment with these drugs. In conclusion, proposed drug combination is a viable option to treatment of polycystic ovary syndrome and improved fetal development. This article allows suggest that further research should be conducted to examine effects associated with these drugs in the treatment of diseases of the female reproductive system experimentally. Only such treatment later in animals and humans suggest

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Retocolite ulcerativa ou colite por citomegalovírus em paciente portador de doença renal crônica em hemodiálise

Ulcerative colitis (UC) is a chronic inflammatory bowel disorder affecting the colon and rectum with pathogenesis associated with immune disorders and immunosuppression-based treatment. The immune system of patients on hemodialysis (HD) is suppressed by the uremic environment and the use of immunosuppressives drugs can lead to opportunistic infections such as cytomegalovirus (CMV). CMV infection can lead to relapse or alter the course of UC. This article reports the case of a 42-year-old male patient with chronic kidney disease (CKD) with no defined etiology, in HD for 6 years, without any clinical intercurrence until then, who presented with severe pancolitis, with initial endoscopic and histological diagnosis of UC. He evolved refractory to clinical treatment, being submitted to total colectomy and ileostomy. The microscopic analysis of the surgical specimen revealed in addition to a chronic inflammatory process the presence of atypical endothelial cells suggestive of CMV infection, confirmed by immunohistochemistry. There was a clinical improvement after treatment with ganciclovir. The findings of this patient emphasize the importance of considering the possibility of UC and CMV colitis as a differential diagnosis in patients with CKD in HD who present with fever and bloody diarrhea, especially in those who do not respond to the initial clinical treatment. A retocolite ulcerativa (RCU) é um distúrbio intestinal inflamatório crônico que acomete o cólon e o reto, com patogênese associada a distúrbios imunológicos e tratamento baseado em imunossupressão. O sistema imune de pacientes em hemodiálise (HD) é suprimido pelo meio urêmico e o uso de imunossupressores pode levar a infecções oportunistas, como citomegalovírus (CMV). A infecção por CMV pode levar a recaída ou alterar o curso da RCU. O presente artigo relata o caso de um paciente do sexo masculino, 42 anos, portador de doença renal crônica (DRC) sem etiologia definida, em HD há seis anos, sem nenhuma intercorrência clínica até então, que apresentou um quadro grave de pancolite, com diagnóstico endoscópico e histopatológico inicial de RCU, evoluiu com refratariedade ao tratamento clínico, sendo submetido à colectomia total e ileostomia, tendo a análise microscópica da peça cirúrgica revelado além de processo inflamatório crônico, a presença de atipias em células endoteliais sugestivas de infecção viral por CMV, confirmada por imunohistoquímica, com melhora clínica após tratamento com ganciclovir. Os achados desse paciente enfatizam a importância de considerar a possibilidade de RCU e colite por CMV como diagnóstico diferencial nos pacientes com DRC em HD que apresentam febre e diarreia sanguinolenta, especialmente naqueles que não respondem ao tratamento clínico inicial.

Educação escolar e construção da consciência: a importância da formação e atuação intencionais do professor para um processo educativo de qualidade

O presente artigo procurou abordar as implicações do Projeto de Intervenção e Pesquisa realizado pela equipe GEIPEE-thc (Grupo de Estudos Intervenção e Pesquisa em Educação Escolar e Especial) Teoria histórico- Cultural da UNESP-Presidente Prudente numa escola pública municipal de Ensino Fundamental da cidade de Presidente Prudente/SP, que atende estudantes oriundos de diversos bairros considerados como áreas de exclusão social e pobreza, numa perspectiva de formação dos professores que avance a formação inicial de modo a contribuir com seu trabalho a apartir da realidade escolar vivenciadas por eles. No decorrer do projeto de intervenção foram realizadas importantes discussões entre os profissionais atuantes na escola para que o desenvolvimento dos indivíduos caminhasse em direção ao processo de humanização dos sujeitos escolares. As intervenções e pesquisa no interior da escola se deram por meio de aulas de Educação Física aplicadas pelo GEIPEE-thc que procurou analisar de forma realista e fidedigna, as condições histórico-sociais dos estudantes participantes do Projeto, suas atitudes e manifestações que vão contra valores humano-genéricos, assim como as situações educacionais vividas por esses sujeitos no interior da escola. Paralelamente foram realizados encontros com os professores das respectivas turmas nos momentos de HTPC (Horário de Trabalho Pedagógico Coletivo), com o intuito de propor momentos de reflexão sobre a prática pedagógica, tendo em vista a superação de dificuldades, conflitos e situações de violência e/ou indisciplina encontradas no decorrer de suas ações na sala de aula e em outros espaços da escola, sendo que tal momento será objeto de análise nesse artigo

Núcleos de Ensino da Unesp: artigos 2014: volume 4: os processos de interação na escola e educação inclusiva

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Núcleos de Ensino da Unesp: artigos 2013: volume 2: metodologias de ensino e a apropriação de conhecimento pelos alunos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP