Associations between neighborhood park space and cognition in older adults vary by US location: The Multi-Ethnic Study of Atherosclerosis

We used cross-sectional Multi-Ethnic Study of Atherosclerosis data from six US cities/counties and adjusted multilevel linear regression to examine park space-cognition associations among non-demented older adults (n = 4084). We found that greater neighborhood park space 1-mile around the residence (measured continuously) was associated with better processing speed in the overall sample (estimate: 0.48; 95% CI: 0.03, 0.92). However, greater neighborhood park space (½-mile around residence) was associated with worse global cognition in Los Angeles, California (estimate: -2.66; 95% CI: -4.70, −0.62) and worse processing speed in Forsyth County, North Carolina (estimate: -0.72; 95% CI: -1.37, −0.08). Dichotomizing at the mean, having ≥6% park space (½-mile around residence) was associated with better global cognition in Saint Paul, Minnesota (estimate: 0.21; 95% CI: 0.05, 0.38), and better processing speed in New York City (estimate: 0.19; 95% CI: 0.04, 0.35). Park space-cognition associations varied by city/county, suggesting problems with pooling multiple sites without accounting for geographic context or regionally-varying park characteristics (e.g., quality)

Concentrações de imunoglobulinas G em colostro de vacas mestiças holandês-zebu Colostral immunoglobulin G concentrations in crossbred holstein-zebu dairy cows

Oitenta e oito vacas leiteiras mestiças holandês-zebu (HZ) foram distribuídas de acordo com a percentagem de grau de sangue holandês em quatro grupos: Grupo 1 = animais com menos de 70% de grau de sangue holandês (19 vacas); Grupo 2 = animais com 75% de grau de sangue holandês, que equivale a ¾ HZ (46 vacas); Grupo 3 = mestiços entre 80 e 90% de grau de sangue holandês, que corresponderam a 13/16 HZ e 7/8 HZ (11 vacas); Grupo 4 = vacas com mais de 90% de grau de sangue holandês (12 vacas). Após o parto, amostras de colostro da primeira ordenha foram colhidas e, posteriormente, submetidas à imunodifusão radial simples para determinações dos níveis de imunoglobulinas G (IgG). Os resultados obtidos permitiram concluir que as concentrações de IgG não são influenciadas pelos graus de sangue estudados e seus valores médios (145,94mg/m<img src="http:/img/fbpe/cr/v31n6/a19img01.gif">) são muito superiores aos relatados para animais de raças taurinas puras. Por esse motivo, não se justifica o emprego de métodos artificiais de fornecimento do colostro em se tratando de mestiços HZ. Ademais, o nível elevado de IgG observado no colostro sugere que a adoção da prática da mamada natural assistida seja adequada para assegurar que, na maioria das vezes, os neonatos não venham a apresentar falhas de transferência de imunidade passiva.<br>Eighty-eight healthy crossbred holstein-zebu (HZ) dairy cows were distributed in four groups as follow: Group 1 = less than 70% HZ (19 cows); Group 2 = 75% HZ animals, corresponding to ¾ HZ (46 cows); Group 3 = crossbred animals between 80 to 90% HZ, corresponding to 13/16 HZ and 7/8 HZ (11 cows); Group 4 = cows more than 90% HZ (12 animals). After birth, colostrum samples were obtained from each cow and than were analyzed for immunoglobulin G (IgG) concentration by single radial immunodifusion assay. IgG colostral concentrations were not influenced by group of crossbred HZ and its mean concentration (145.97mg/m<img src="http:/img/fbpe/cr/v31n6/a19img01.gif">) were higher than that related for purebreds Bos taurus dairy cows. Considering these results, it was concluded that artificial methods of feeding colostrum to crossbred HZ calves are not necessary. Probably, assisted natural sucking as soon after birth as possible is enough to get passive immune transfer