18 research outputs found

    Magnetic crystals and helical liquids in alkaline-earth fermionic gases

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    The joint action of a synthetic gauge potential and of atomic contact repulsion in a one-dimensional alkaline-earth(-like) fermionic gas with nuclear spin I leads to the existence of a hierarchy of fractional insulating and conducting states with intriguing properties. We unveil the existence and the features of those phases by means of both analytical bosonization techniques and numerical methods based on the density-matrix renormalization group algorithm. In particular, we show that the gapless phases can support helical modes, whereas the gapped states, which appear under certain conditions, are characterised both by density and magnetic order. Several distinct features emerge solely for spin I larger than 1/2, thus making their study with cold-atoms unique. We will finally argue that these states are related to the properties of an unconventional fractional quantum Hall effect in the thin-torus limit. The properties of this hierarchy of states can be experimentally studied in state-of-the-art cold-atom laboratories

    Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

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    Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.

    Quantum Oscillations and Magnetoresistance in Type-II Weyl Semimetals - Effect of a Field Induced Charge Density Wave

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    Recent experiments on type-II Weyl semimetals such as WTe2_2, MoTe2_2, Mox_xW1x_{1-x}Te2_2 and WP2_2 reveal remarkable transport properties in presence of a strong magnetic field, including an extremely large magnetoresistance and an unusual temperature dependence. Here, we investigate magnetotransport via the Kubo formula in a minimal model of a type-II Weyl semimetal taking into account the effect of a charge density wave (CDW) transition, which can arise even at weak coupling in the presence of a strong magnetic field because of the special Landau level dispersion of type-II Weyl systems. Consistent with experimental measurements we find an extremely large magnetoresistance with close to B2B^2 scaling at particle-hole compensation, while in the extreme quantum limit there is a transition to a qualitatively new scaling with approximately B0.75B^{0.75}. We also investigate the Shubnikov-de Haas effect and find that the amplitude of the resistivity quantum oscillations are greatly enhanced below the CDW transition temperature which is accompanied by an unusual non-monotonous (non-Lifshitz-Kosevich) temperature dependence

    Bulk-edge correspondence in fractional Chern insulators

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    It has been recently realized that strong interactions in topological Bloch bands give rise to the appearance of novel states of matter. Here we study connections between these systems—fractional Chern insulators and the fractional quantum Hall states—via generalization of a gauge-fixed Wannier-Qi construction in the cylinder geometry. Our setup offers a number of important advantages compared to the earlier exact diagonalization studies on a torus. Most notably, it gives access to edge states and to a single-cut orbital entanglement spectrum, hence to the physics of bulk-edge correspondence. It is also readily implemented in the state-of-the-art density matrix renormalization group method that allows for numerical simulations of significantly larger systems. We demonstrate our general approach on examples of flat-band models on ruby and kagome lattices at bosonic filling fractions ν = 1/2 and ν = 1, which show the signatures of (non)-Abelian phases, and establish the correspondence between the physics of edge states and the entanglement in the bulk. Notably, we find that the non-Abelian ν = 1 phase can be stabilized by purely on-site interactions in the presence of a confining potential

    Jack on a Devil’s Staircase

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    We review a simple mechanism for the formation of plateaux in the fractional quantum Hall effect. It arises from a map of the microscopic Hamilto- nian in the thin torus limit to a lattice gas model, solved by Hubbard. The map suggests a Devil\u2019s staircase pattern, and explains the observed asymmetries in the widths. Each plateau is a new ground state of the system: a periodic Slater state in the thin torus limit. We provide the unitary operator that maps such limit states to the full, effective ground states with same filling fraction. These Jack polynomials generalise Laughlin\u2019s ansatz, and are exact eigenstates of the Laplace-Beltrami operator. Why are Jacks sitting on the Devil\u2019s staircase? This is yet an intriguing problem. Talk given in Milan, Congresso di Dipartimento 2017 (L.G.M.)

    Discovery of a new type of topological Weyl fermion semimetal state in MoxW1-xTe2

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    [[abstract]]The recent discovery of a Weyl semimetal in TaAs offers the first Weyl fermion observed in nature and dramatically broadens the classification of topological phases. However, in TaAs it has proven challenging to study the rich transport phenomena arising from emergent Weyl fermions. The series MoxW1−xTe2 are inversion-breaking, layered, tunable semimetals already under study as a promising platform for new electronics and recently proposed to host Type II, or strongly Lorentz-violating, Weyl fermions. Here we report the discovery of a Weyl semimetal in MoxW1−xTe2 at x=25%. We use pump-probe angle-resolved photoemission spectroscopy (pump-probe ARPES) to directly observe a topological Fermi arc above the Fermi level, demonstrating a Weyl semimetal. The excellent agreement with calculation suggests that MoxW1−xTe2 is a Type II Weyl semimetal. We also find that certain Weyl points are at the Fermi level, making MoxW1−xTe2 a promising platform for transport and optics experiments on Weyl semimetals.[[notice]]補正完
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