661 research outputs found

    Student Recital: David Pearce, Trumpet; Rex Benson, Euphonium; Joe Hesh, Piano; Kent Wehman, Piano; April 28, 1974

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    Centennial East Recital HallSunday EveningApril 28, 19748:15 p.m

    Delay Jitter Bounds and Packet Scale Rate Guarantee for Expedited Forwarding

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    We consider the definition of the Expedited Forwarding Per-Hop Behaviour (EF PHB) as given in RFC 2598, and its impact on worst case end-to-end delay jitter. On one hand, the definition in RFC 2598 can be used to predict extremely low end-to-end delay jitter, independent of the network scale. On the other hand, we find that the worst case delay jitter can be made arbitrarily large, while each flow traverses at most a specified number of hops, if we allow networks to become arbitrarily large, this is in contradiction with the previous statement. We analyze where the contradiction originates, and find the explanation. It resides in the fact that the definition in RFC 2598 is not easily implementable in schedulers we know of, mainly because it is not formal enough, and also because it does not contain an error term. We propose a new definition for the EF PHB, called ``Packet Scale Rate Guarante

    Accelerated Evolution of the ASPM Gene Controlling Brain Size Begins Prior to Human Brain Expansion

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    Primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by global reduction in cerebral cortical volume. The microcephalic brain has a volume comparable to that of early hominids, raising the possibility that some MCPH genes may have been evolutionary targets in the expansion of the cerebral cortex in mammals and especially primates. Mutations in ASPM, which encodes the human homologue of a fly protein essential for spindle function, are the most common known cause of MCPH. Here we have isolated large genomic clones containing the complete ASPM gene, including promoter regions and introns, from chimpanzee, gorilla, orangutan, and rhesus macaque by transformation-associated recombination cloning in yeast. We have sequenced these clones and show that whereas much of the sequence of ASPM is substantially conserved among primates, specific segments are subject to high Ka/Ks ratios (nonsynonymous/synonymous DNA changes) consistent with strong positive selection for evolutionary change. The ASPM gene sequence shows accelerated evolution in the African hominoid clade, and this precedes hominid brain expansion by several million years. Gorilla and human lineages show particularly accelerated evolution in the IQ domain of ASPM. Moreover, ASPM regions under positive selection in primates are also the most highly diverged regions between primates and nonprimate mammals. We report the first direct application of TAR cloning technology to the study of human evolution. Our data suggest that evolutionary selection of specific segments of the ASPM sequence strongly relates to differences in cerebral cortical size

    Simulating the Formation of the Local Galaxy Population

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    We simulate the formation and evolution of the local galaxy population starting from initial conditions with a smoothed linear density field which matches that derived from the IRAS 1.2 Jy galaxy survey. Our simulations track the formation and evolution of all dark matter haloes more massive than 10e+11 solar masses out to a distance of 8000 km/s from the Milky Way. We implement prescriptions similar to those of Kauffmann et al. (1999) to follow the assembly and evolution of the galaxies within these haloes. We focus on two variants of the CDM cosmology: an LCDM and a tCDM model. Galaxy formation in each is adjusted to reproduce the I-band Tully-Fisher relation of Giovanelli et al. (1997). We compare the present-day luminosity functions, colours, morphology and spatial distribution of our simulated galaxies with those of the real local population, in particular with the Updated Zwicky Catalog, with the IRAS PSCz redshift survey, and with individual local clusters such as Coma, Virgo and Perseus. We also use the simulations to study the clustering bias between the dark matter and galaxies of differing type. Although some significant discrepancies remain, our simulations recover the observed intrinsic properties and the observed spatial distribution of local galaxies reasonably well. They can thus be used to calibrate methods which use the observed local galaxy population to estimate the cosmic density parameter or to draw conclusions about the mechanisms of galaxy formation. To facilitate such work, we publically release our z=0 galaxy catalogues, together with the underlying mass distribution.Comment: 25 pages, 20 figures, submitted to MNRAS. High resolution copies of figures 1 and 3, halo and galaxy catalogues can be found at http://www.mpa-garching.mpg.de/NumCos/CR/index.htm

    Detection and characterization of local inverted repeats regularities

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    To explore the inverted repeats regularities along the genome sequences, we propose a sliding window method to extract the concentration scores of inverted repeats periodic regularities and the total mass of possible inverted repeats pairs. We apply the method to the human genome and locate the regions with the potential for the formation of large number of hairpin/cruciform structures. The number of found windows with periodic regularities is small and the patterns of occurrence are chromosome specific.publishe

    Populating a cluster of galaxies - I. Results at z=0

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    We simulate the assembly of a massive rich cluster and the formation of its constituent galaxies in a flat, low-density universe. Our most accurate model follows the collapse, the star-formation history and the orbital motion of all galaxies more luminous than the Fornax dwarf spheroidal, while dark halo structure is tracked consistently throughout the cluster for all galaxies more luminous than the SMC. Within its virial radius this model contains about 2.0e7 dark matter particles and almost 5000 distinct dynamically resolved galaxies. Simulations of this same cluster at a variety of resolutions allow us to check explicitly for numerical convergence both of the dark matter structures produced by our new parallel N-body and substructure identification codes, and of the galaxy populations produced by the phenomenological models we use to follow cooling, star formation, feedback and stellar aging. This baryonic modelling is tuned so that our simulations reproduce the observed properties of isolated spirals outside clusters. Without further parameter adjustment our simulations then produce a luminosity function, a mass-to-light ratio, luminosity, number and velocity dispersion profiles, and a morphology-radius relation which are similar to those observed in real clusters. In particular, since our simulations follow galaxy merging explicitly, we can demonstrate that it accounts quantitatively for the observed cluster population of bulges and elliptical galaxies.Comment: 28 pages, submitted to MNRA

    Astrophysically Motivated Bulge-Disk Decompositions of SDSS Galaxies

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    We present a set of bulge-disk decompositions for a sample of 71,825 SDSS main-sample galaxies in the redshift range 0.003<z<0.05. We have fit each galaxy with either a de Vaucouleurs ('classical') or an exponential ('pseudo-') bulge and an exponential disk. Two dimensional Sersic fits are performed when the 2-component fits are not statistically significant or when the fits are poor, even in the presence of high signal-to-noise. We study the robustness of our 2-component fits by studying a bright subsample of galaxies and we study the systematics of these fits with decreasing resolution and S/N. Only 30% of our sample have been fit with two-component fits in which both components are non-zero. The g-r and g-i colours of each component for the two-component models are determined using linear templates derived from the r-band model. We attempt a physical classification of types of fits into disk galaxies, pseudo-bulges, classical bulges, and ellipticals. Our classification of galaxies agrees well with previous large B+D decomposed samples. Using our galaxy classifications, we find that Petrosian concentration is a good indicator of B/T, while overall Sersic index is not. Additionally, we find that the majority of green valley galaxies are bulge+disk galaxies. Furthermore, in the transition from green to red B+D galaxies, the total galaxy colour is most strongly correlated with the disk colour.Comment: 28 pages, 34 figures, MNRAS accepte
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