6,906 research outputs found
A Free-Form Lensing Grid Solution for A1689 with New Mutiple Images
Hubble Space Telescope imaging of the galaxy cluster Abell 1689 has revealed
an exceptional number of strongly lensed multiply-imaged galaxies, including
high-redshift candidates. Previous studies have used this data to obtain the
most detailed dark matter reconstructions of any galaxy cluster to date,
resolving substructures ~25 kpc across. We examine Abell 1689 (hereafter,
A1689) non-parametrically, combining strongly lensed images and weak
distortions from wider field Subaru imaging, and we incorporate member galaxies
to improve the lens solution. Strongly lensed galaxies are often locally
affected by member galaxies, however, these perturbations cannot be recovered
in grid based reconstructions because the lensing information is too sparse to
resolve member galaxies. By adding luminosity-scaled member galaxy deflections
to our smooth grid we can derive meaningful solutions with sufficient accuracy
to permit the identification of our own strongly lensed images, so our model
becomes self consistent. We identify 11 new multiply lensed system candidates
and clarify previously ambiguous cases, in the deepest optical and NIR data to
date from Hubble and Subaru. Our improved spatial resolution brings up new
features not seen when the weak and strong lensing effects are used separately,
including clumps and filamentary dark matter around the main halo. Our
treatment means we can obtain an objective mass ratio between the cluster and
galaxy components, for examining the extent of tidal stripping of the luminous
member galaxies. We find a typical mass-to-light ratios of M/L_B = 21 inside
the r<1 arcminute region that drops to M/L_B = 17 inside the r<40 arcsecond
region. Our model independence means we can objectively evaluate the
competitiveness of stacking cluster lenses for defining the geometric
lensing-distance-redshift relation in a model independent way.Comment: 23 pages with 25 figures Replced with MNRAS submitted version. Some
figures have been corrected and minor text edit
Resonances, and mechanisms of Theta-production
After explaining necessity of exotic hadrons, we discuss mechanisms which
could determine production of the exotic Theta-baryon. A possible important
role of resonances (producing the Theta in real or virtual decays) is
emphasized for various processes. Several experimental directions for studies
of such resonances, and the Theta itself, are suggested. We briefly discuss
also recent negative results on the Theta-baryon.Comment: 6 page
Transverse momentum spectra of identified particles in high energy collisions with statistical hadronisation model
A detailed analysis is performed of transverse momentum spectra of several
identified hadrons in high energy collisions within the framework of the
statistical model of hadronisation. The effect of the decay chain following
hadron generation is accurately taken into account. The considered
centre-of-mass energies range from ~ 10 to 30 GeV in hadronic collisions (pi+
p, pp and Kp) and from ~ 15 to 45 GeV in e+e- collisions. A clear consistency
is found between the temperature parameter extracted from the present analysis
and that obtained from fits to average hadron multiplicities in the same
collision systems. This finding indicates that in the hadronisation, the
production of different particle species and their momentum spectra are two
closely related phenomenons governed by one parameter.Comment: Talk given by F. Becattini in "Correlations and Fluctuations 2000",
12 pp., 11 figure
Expression and cellular localization of the transcription factor NeuroD1 in the developing and adult rat pineal gland
Circadian rhythms govern many aspects of mammalian physiology. The daily pattern of melatonin synthesis and secretion is one of the classic examples of circadian oscillations. It is mediated by a class of neuroendocrine cells known as pinealocytes which are not yet fully defined. An established method to evaluate functional and cytological characters is through the expression of lineageâspecific transcriptional regulators. NeuroD1 is a basic helixâloopâhelix transcription factor involved in the specification and maintenance of both endocrine and neuronal phenotypes. We have previously described developmental and adult regulation of NeuroD1 mRNA in the rodent pineal gland. However, the transcript levels were not influenced by the elimination of sympathetic input, suggesting that any rhythmicity of NeuroD1 might be found downstream of transcription. Here, we describe NeuroD1 protein expression and cellular localization in the rat pineal gland during development and the daily cycle. In embryonic and perinatal stages, protein expression follows the mRNA pattern and is predominantly nuclear. Thereafter, NeuroD1 is mostly found in pinealocyte nuclei in the early part of the night and in cytoplasm during the day, a rhythm maintained into adulthood. Additionally, nocturnal nuclear NeuroD1 levels are reduced after sympathetic disruption, an effect mimicked by the in vivo administration of αâ and ÎČâadrenoceptor blockers. NeuroD1 phosphorylation at two sites, Ser274 and Ser336, associates with nuclear localization in pinealocytes. These data suggest that NeuroD1 influences pineal phenotype both during development and adulthood, in an autonomic and phosphorylationâdependent manner.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111177/1/jpi12228.pd
Hadronic Masses and Regge Trajectories
A comprehensive phenomenological analysis of experimental data and some
theoretical models is presented here (for mesons) to critically discuss how
Regge trajectory parameters depend on flavor. Through analytic continuation of
physical trajectories (obtained from resonance data) into the space like
region, we derive the suppression factor for heavy flavor production. The case
of our D Regge exchange, both for D and production, is considered
in some detail. Good agreement with data is reached confirming that indeed the
slopes of heavier flavors decrease. This result suggests that the confinement
potential has a substantial dependence on the quark masses. In a simple
non-relativistic model, constrained to produce linear Regge trajectories, it is
shown that a linear quark mass dependence is required (in the confinement part
of the potential) in order for the slope to decrease in the appropriate way.Comment: 19 pages, 9 Figures, IV Table
Sub-mm detection of a high redshift Type 2 QSO
We report on the first SCUBA detection of a Type 2 QSO at z=3.660 in the
Chandra Deep Field South. This source is X-ray absorbed, shows only narrow
emission lines in the optical spectrum and is detected in the sub-mm: it is the
ideal candidate in an evolution scheme for AGN (e.g. Fabian (1999); Page et al.
(2004)) of an early phase corresponding to the main growth of the host galaxy
and formation of the central black hole. The overall photometry (from the radio
to the X-ray energy band) of this source is well reproduced by the spectral
energy distribution (SED) of NGC 6240, while it is incompatible with the
spectrum of a Type 1 QSO (3C273) or a starburst galaxy (Arp 220). Its sub-mm
(850 \mu m) to X-ray (2 keV) spectral slope (alpha_SX) is close to the
predicted value for a Compton-thick AGN in which only 1% of the nuclear
emission emerges through scattering. Using the observed flux at 850 \mu m we
have derived a SFR=550--680 M_dust=4.2 10^8 M_odotComment: 6 Pages, 5 Figures, accepted for publication in MNRA
Deep Imaging of AXJ2019+112: The Luminosity of a ``Dark Cluster''
We detect a distant cluster of galaxies centered on the QSO lens and luminous
X-ray source AXJ2019+112, a.k.a. ``The Dark Cluster'' (Hattori et al 1997).
Using deep V,I Keck images and wide-field K_s imaging from the NTT, a tight red
sequence of galaxies is identified within a radius of 0.2 h^{-1} Mpc of the
known z=1.01 elliptical lensing galaxy. The sequence, which includes the
central elliptical galaxy, has a slope in good agreement with the model
predictions of Kodama et al (1998) for z~1. We estimate the integrated
rest-frame luminosity of the cluster to be L_V > 3.2 x 10^{11}h^{-2}L_{\sun}
(after accounting for significant extinction at the low latitude of this
field), more than an order of magnitude higher than previous estimates. The
central region of the cluster is deconvolved using the technique of Magain,
Courbin & Sohy (1998), revealing a thick central arc coincident with an
extended radio source. All the observed lensing features are readily explained
by differential magnification of a radio loud AGN by a shallow elliptical
potential. The QSO must lie just outside the diamond caustic, producing two
images, and the arc is a highly magnified image formed from a region close to
the center of the host galaxy, projecting inside the caustic. The
mass--to--light ratio within an aperture of 0.4 h ^{-1} Mpc is M_x/L_V=
224^{+112}_{-78}h(M/L_V)_{\sun}, using the X-ray temperature. The strong lens
model yields a compatible value, M/L_V= 372^{+94}_{-94}h(M/L_V)_{\sun}, whereas
an independent weak lensing analysis sets an upper limit of M/L_V <520
h(M/L_V)_{\sun}, typical of massive clusters.Comment: AAS Latex format, 24 pages, 9 figures. Fig 1a,b available at
http://astro.berkeley.edu/~benitezn/cluster.html . Submitted to ApJ on August
15t
JPCam: A 1.2Gpixel camera for the J-PAS survey
JPCam is a 14-CCD mosaic camera, using the new e2v 9k-by-9k 10microm-pixel
16-channel detectors, to be deployed on a dedicated 2.55m wide-field telescope
at the OAJ (Observatorio Astrofisico de Javalambre) in Aragon, Spain. The
camera is designed to perform a Baryon Acoustic Oscillations (BAO) survey of
the northern sky. The J-PAS survey strategy will use 54 relatively narrow-band
(~13.8nm) filters equi-spaced between 370 and 920nm plus 3 broad-band filters
to achieve unprecedented photometric red-shift accuracies for faint galaxies
over ~8000 square degrees of sky. The cryostat, detector mosaic and read
electronics is being supplied by e2v under contract to J-PAS while the
mechanical structure, housing the shutter and filter assembly, is being
designed and constructed by a Brazilian consortium led by INPE (Instituto
Nacional de Pesquisas Espaciais). Four sets of 14 filters are placed in the
ambient environment, just above the dewar window but directly in line with the
detectors, leading to a mosaic having ~10mm gaps between each CCD. The massive
500mm aperture shutter is expected to be supplied by the Argelander-Institut
fur Astronomie, Bonn. We will present an overview of JPCam, from the filter
configuration through to the CCD mosaic camera. A brief outline of the main
J-PAS science projects will be included.Comment: 11 pages and 9 figure
Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after FcÎłRII-mediated uptake
Plasmacytoid dendritic cells (pDCs) contribute to innate antiviral immune responses by producing type I interferons. Although human pDCs can induce T cell responses upon viral infection, it remains unclear if pDCs can present exogenous antigens. Here, we show that human pDCs exploit FcÎłRII (CD32) to internalize antigenâantibody complexes, resulting in the presentation of exogenous antigen to T cells. pDCs isolated from melanoma patients vaccinated with autologous monocyte-derived peptide- and keyhold limpet hemocyanin (KLH)âloaded dendritic cells, but not from nonvaccinated patients or patients that lack a humoral response against KLH, were able to stimulate KLH-specific T cell proliferation. Interestingly, we observed that internalization of KLH by pDCs depended on the presence of serum from vaccinated patients that developed an anti-KLH antibody response. Anti-CD32 antibodies inhibited antigen uptake and presentation, demonstrating that circulating anti-KLH antibodies binding to CD32 mediate KLH internalization. We conclude that CD32 is an antigen uptake receptor on pDCs and that antigen presentation by pDCs is of particular relevance when circulating antibodies are present. Antigen presentation by pDCs may thus modulate the strength and quality of the secondary phase of an immune response
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