1,414 research outputs found

    Exploring Mars Glass Tube Anomalies

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    This practical article provides information regarding the use of Edward de Bono CoRT thinking skills to broaden and enhance critical and creative thinking skills in twice exceptional students using the Mars Glass Tube Mystery as a vehicle to explore possibilities and spark creative thinking. The exceptionalities addressed in this lesson plan are gifted learners who have one or more additional exceptionalities of slow processing speed and / or poor fine motor skills. Throughout the lesson, the Mars Mystery photos leveraged both prior knowledge and student curiosity to create an engaging activity for the participants. CoRT thinking skills provided a robust structure for guiding meaningful discussions, a means of encouraging deeper thought, and facilitating productive group discourse. The mystery-focused lesson encouraged imagination, allowing students to not only stretch independent thought but to actively participate in sharing and validating each other’s ideas and to explore creativity as a way to express ideas and generate conclusions

    Computer-supported Exploration of a Categorical Axiomatization of Modeloids

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    A modeloid, a certain set of partial bijections, emerges from the idea to abstract from a structure to the set of its partial automorphisms. It comes with an operation, called the derivative, which is inspired by Ehrenfeucht-Fra\"iss\'e games. In this paper we develop a generalization of a modeloid first to an inverse semigroup and then to an inverse category using an axiomatic approach to category theory. We then show that this formulation enables a purely algebraic view on Ehrenfeucht-Fra\"iss\'e games.Comment: 24 pages; accepted for conference: Relational and Algebraic Methods in Computer Science (RAMICS 2020

    PV cell angle optimization for energy generation-consumption matching in a solar powered cellular network

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    An inherent problem of solar-energy-powered-smallcell base stations (SBSs) is that the energy generation of the photovoltaic (PV) cell does not match the energy consumption of the SBS in time. In this paper, we propose to optimize the PV cell orientation angle to achieve a good match between the energy generation and consumption profiles on a daily time scale. The optimization is formulated as an integer linear programming problem. We also derive an expression for the correlation between the energy generation and consumption profiles to evaluate their general interaction independent of the exact PV cell or SBS deployment setup. The numerical evaluation of the proposed angle optimization in a business area in London in summer/winter shows that the optimal PV cell orientation in summer contradicts the conventional assumption of south facing being optimal in the northern hemisphere. Instead, a southwest orientation should be chosen in summer due to its ability to shift the energy generation peak towards the energy consumption peak in the afternoon at a SBS in central London. This is in accordance with the prediction given by our derived correlation between the solar energy generation and consumption profiles

    The Effect of Bicarbonate Administration via Continuous Venovenous Hemofiltration on Acid-Base Parameters in Ventilated Patients

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    Background. Acute kidney injury (AKI) and metabolic acidosis are common in the intensive care unit. The effect of bicarbonate administration on acid-base parameters is unclear in those receiving continuous venovenous hemofiltration (CVVH) and mechanical ventilatory support. Methods. Metabolic and ventilatory parameters were prospectively examined in 19 ventilated subjects for up to 96 hours following CVVH initiation for AKI at an academic tertiary care center. Mixed linear regression modeling was performed to measure changes in pH, partial pressure of carbon dioxide (pCO2), serum bicarbonate, and base excess over time. Results. During the 96-hour study period, pCO2 levels remained stable overall (initial pCO2 42.0 ± 14.6 versus end-study pCO2 43.8 ± 16.1 mmHg; P=0.13 for interaction with time), for those with initial pCO2 ≀40 mmHg (31.3 ± 5.7 versus 35.0 ± 4.8; P=0.06) and for those with initial pCO2 >40 mmHg (52.7 ± 12.8 versus 53.4 ± 19.2; P=0.57). pCO2 decreased during the immediate hours following CVVH initiation (42.0 ± 14.6 versus 37.3 ± 12.6 mmHg), though this change was nonsignificant (P=0.052). Conclusions. We did not detect a significant increase in pCO2 in response to the administration of bicarbonate via CVVH in a ventilated population. Additional studies of larger populations are needed to confirm this finding

    Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors

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    The eukaryotic RNA exosome participates extensively in RNA processing and degradation. In human cells, three accessory factors (RBM7, ZCCHC8 and hMTR4) interact to form the nuclear exosome targeting (NEXT) complex, which directs a subset of non-coding RNAs for exosomal degradation. Here we elucidate how RBM7 is incorporated in the NEXT complex. We identify a proline-rich segment of ZCCHC8 as the interaction site for the RNA-recognition motif (RRM) of RBM7 and present the crystal structure of the corresponding complex at 2.0 resolution. On the basis of the structure, we identify a proline-rich segment within the splicing factor SAP145 with strong similarity to ZCCHC8. We show that this segment of SAP145 not only binds the RRM region of another splicing factor SAP49 but also the RRM of RBM7. These dual interactions of RBM7 with the exosome and the spliceosome suggest a model whereby NEXT might recruit the exosome to degrade intronic RNAs

    SzĂĄmtan

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    PF-13 Fracture Fixation between Os Lumbalis II and III on a Three Month Old Kitten Using Parallel Technique

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    Spinal fractures, luxations, and fracture- luxations in dogs and cats are common and are often the result of vehicular injury. Other frequent causes of injury include animal attacks or falling from a height. Reports that describe the distribution of spinal column injuries indicate that they affect the lumbar vertebrae most frequently, followed by sacrococcygeal, thoracic, and cervical vertebrae2,3

    Separating underwater ambient noise from flow noise recorded on stereo acoustic tags attached to marine mammals

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    A.M.v.B.B. and P.B. were funded by The Netherlands Ministry of Defence. Fieldwork efforts and support for P.M. and F.S. was provided by the US Office of Naval Research [award numbers N00014-08-1-0984 and N00014-10-1-0355]. P.W. received a PhD studentship with matched funding from The Netherlands Ministry of Defence (administered by The Netherlands Organisation for Applied Scientific Research, TNO) and UK Natural Environment Research Council [NE/J500276/1].Sound-recording acoustic tags attached to marine animals are commonly used in behavioural studies. Measuring ambient noise is of interest to efforts to understand responses of marine mammals to anthropogenic underwater sound, or to assess their communication space. Noise of water flowing around the tag reflects the speed of the animal, but hinders ambient noise measurement. Here, we describe a correlation-based method for stereo acoustic tags to separate the relative contributions of flow and ambient noise. The uncorrelated part of the noise measured in digital acoustic recording tag (DTAG) recordings related well to swim speed of a humpback whale (Megaptera novaeangliae), thus providing a robust measure of flow noise over a wide frequency bandwidth. By removing measurements affected by flow noise, consistent ambient noise estimates were made for two killer whales (Orcinus orca) with DTAGs attached simultaneously. The method is applicable to any multi-channel acoustic tag, enabling application to a wide range of marine species.Publisher PDFPeer reviewe
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